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Items: 1 to 20 of 34

1.
Sequential administration of XPO1 and ATR inhibitors enhances therapeutic response in TP53-mutated colorectal cancer
Akira Inoue, Frederick S. Robinson, Rosalba Minelli, Hideo Tomihara, Bahar Salimian Rizi, Johnathon L. Rose, Takahiro Kodama, Sanjana Srinivasan, Angela L. Harris, Andy M. Zuniga, Robert A. Mullinax, Xiaoyan Ma, Sahil Seth, Joseph R. Daniele, Michael D. Peoples, Sara Loponte, Kadir C. Akdemir, Tin Oo Khor, Ningping Feng, Jason Roszik, Mary M. Sobieski, David Brunell, Clifford Stephan, Virginia Giuliani, Angela K. Deem, Takashi Shingu, Yonathan Lissanu Deribe, David G. Menter, Timothy P. Heffernan, Andrea Viale, Christopher A. Bristow, Scott Kopetz, Giulio F. Draetta, Giannicola Genovese, Alessandro Carugo
Gastroenterology. Author manuscript; available in PMC 2022 Jul 1.
Published in final edited form as: Gastroenterology. 2021 Jul; 161(1): 196–210. Published online 2021 Mar 19. doi: 10.1053/j.gastro.2021.03.022
PMCID:
PMC8238881
AbstractArticlePDF–2.6M
2.
A novel circular RNA, circXPO1, promotes lung adenocarcinoma progression by interacting with IGF2BP1
Qi Huang, Haifa Guo, Shaodong Wang, Yi Ma, Haiming Chen, Hao Li, Jiawei Li, Xiao Li, Fan Yang, Mantang Qiu, Song Zhao, Jun Wang
Cell Death Dis. 2020 Dec; 11(12): 1031. Published online 2020 Dec 2. doi: 10.1038/s41419-020-03237-8
PMCID:
PMC7710735
AbstractArticlePDF–2.1M
3.
Association of XPO1 Overexpression with NF-κB and Ki67 in Colorectal Cancer
Mohammed Aladhraei, Abdulla Kassem Al-Thobhani, Naravat Poungvarin, Prasit Suwannalert
Asian Pac J Cancer Prev. 2019; 20(12): 3747–3754. doi: 10.31557/APJCP.2019.20.12.3747
PMCID:
PMC7173379
AbstractArticlePDF–914K
4.
Targeting Nuclear Exporter Protein XPO1/CRM1 in Gastric Cancer
Rachel Sexton, Zaid Mahdi, Rahman Chaudhury, Rafic Beydoun, Amro Aboukameel, Husain Y. Khan, Erkan Baloglu, William Senapedis, Yosef Landesman, Anteneh Tesfaye, Steve Kim, Philip A. Philip, Asfar S. Azmi
Int J Mol Sci. 2019 Oct; 20(19): 4826. Published online 2019 Sep 28. doi: 10.3390/ijms20194826
PMCID:
PMC6801932
AbstractArticlePDF–3.4M
5.
Prognostic roles of the transcriptional expression of exportins in hepatocellular carcinoma
Lubiao Chen, Yanlin Huang, Liang Zhou, Yifan Lian, Jialiang Wang, Dongmei Chen, Huan Wei, Mingsheng Huang, Yuehua Huang
Biosci Rep. 2019 Aug 30; 39(8): BSR20190827. Prepublished online 2019 Aug 1. Published online 2019 Aug 19. doi: 10.1042/BSR20190827
PMCID:
PMC6702357
AbstractArticlePDF–1.8M
6.
XPO1 inhibitor KPT-330 synergizes with Bcl-xL inhibitor to induce cancer cell apoptosis by perturbing rRNA processing and Mcl-1 protein synthesis
Zhi-Chuan Zhu, Ji-Wei Liu, Can Yang, Miao Zhao, Zhi-Qi Xiong
Cell Death Dis. 2019 Jun; 10(6): 395. Published online 2019 May 21. doi: 10.1038/s41419-019-1627-9
PMCID:
PMC6529444
AbstractArticlePDF–3.4M
7.
Anti-tumor efficacy of Selinexor (KPT-330) in gastric cancer is dependent on nuclear accumulation of p53 tumor suppressor
Vinod Vijay Subhash, Mei Shi Yeo, Lingzhi Wang, Shi Hui Tan, Foong Ying Wong, Win Lwin Thuya, Woei Loon Tan, Praveen C. Peethala, Mu Yar Soe, David S. P. Tan, Nisha Padmanabhan, Erkan Baloglu, Sharon Shacham, Patrick Tan, H. Phillip Koeffler, Wei Peng Yong
Sci Rep. 2018; 8: 12248. Published online 2018 Aug 16. doi: 10.1038/s41598-018-30686-1
PMCID:
PMC6095850
AbstractArticlePDF–1.5M
8.
Nuclear export of ubiquitinated proteins via the UBIN-POST system
Shoshiro Hirayama, Munechika Sugihara, Daisuke Morito, Shun-ichiro Iemura, Tohru Natsume, Shigeo Murata, Kazuhiro Nagata
Proc Natl Acad Sci U S A. 2018 May 1; 115(18): E4199–E4208. Published online 2018 Apr 16. doi: 10.1073/pnas.1711017115
PMCID:
PMC5939056
AbstractArticlePDF–1.8M
9.
Expression of CRM1 and CDK5 shows high prognostic accuracy for gastric cancer
Yu-Qin Sun, Jian-Wei Xie, Hong-Teng Xie, Peng-Chen Chen, Xiu-Li Zhang, Chao-Hui Zheng, Ping Li, Jia-Bin Wang, Jian-Xian Lin, Long-Long Cao, Chang-Ming Huang, Yao Lin
World J Gastroenterol. 2017 Mar 21; 23(11): 2012–2022. Published online 2017 Mar 21. doi: 10.3748/wjg.v23.i11.2012
PMCID:
PMC5360642
AbstractArticlePDF–1.1M
10.
Suppressing activity of tributyrin on hepatocarcinogenesis is associated with inhibiting the p53-CRM1 interaction and changing the cellular compartmentalization of p53 protein
Juliana F. Ortega, Aline de Conti, Volodymyr Tryndyak, Kelly S. Furtado, Renato Heidor, Maria Aderuza Horst, Laura Helena Gasparini Fernandes, Paulo Eduardo Latorre Martins Tavares, Marta Pogribna, Svitlana Shpyleva, Frederick A. Beland, Igor P. Pogribny, Fernando Salvador Moreno
Oncotarget. 2016 Apr 26; 7(17): 24339–24347. Published online 2016 Mar 22. doi: 10.18632/oncotarget.8248
PMCID:
PMC5029705
AbstractArticlePDF–1.9M
11.
CRM-1 knockdown inhibits extrahepatic cholangiocarcinoma tumor growth by blocking the nuclear export of p27Kip1
Jian Luo, Yongjun Chen, Qiang Li, Bing Wang, Yanqiong Zhou, Hongzhen Lan
Int J Mol Med. 2016 Aug; 38(2): 381–390. Published online 2016 Jun 7. doi: 10.3892/ijmm.2016.2628
PMCID:
PMC4935460
AbstractArticlePDF–1.2M
12.
RNA Export through the NPC in Eukaryotes
Masumi Okamura, Haruko Inose, Seiji Masuda
Genes (Basel) 2015 Mar; 6(1): 124–149. Published online 2015 Mar 20. doi: 10.3390/genes6010124
PMCID:
PMC4377836
AbstractArticlePDF–12M
13.
KPT-330 inhibitor of XPO1-mediated nuclear export has anti-proliferative activity in hepatocellular carcinoma
Yun Zheng, Sigal Gery, Haibo Sun, Sharon Shacham, Michael Kauffman, H. Phillip Koeffler
Cancer Chemother Pharmacol. Author manuscript; available in PMC 2015 Sep 1.
Published in final edited form as: Cancer Chemother Pharmacol. 2014 Sep; 74(3): 487–495. Published online 2014 Jul 17. doi: 10.1007/s00280-014-2495-8
PMCID:
PMC4146741
AbstractArticlePDF–879K
14.
KPT-330 has antitumour activity against non-small cell lung cancer
H Sun, N Hattori, W Chien, Q Sun, M Sudo, G L E-Ling, L Ding, S L Lim, S Shacham, M Kauffman, T Nakamaki, H P Koeffler
Br J Cancer. 2014 Jul 15; 111(2): 281–291. Published online 2014 Jun 19. doi: 10.1038/bjc.2014.260
PMCID:
PMC4102938
AbstractArticlePDF–1.6M
15.
CRM1 and its ribosome export adaptor NMD3 localize to the nucleolus and affect rRNA synthesis
Baoyan Bai, Henna M Moore, Marikki Laiho
Nucleus. 2013 Jul 1; 4(4): 315–325. Published online 2013 Jun 12. doi: 10.4161/nucl.25342
PMCID:
PMC3810339
AbstractArticlePDF–3.6M
16.
Postage for the messenger: Designating routes for Nuclear mRNA Export
Barbara J. Natalizio, Susan R. Wente
Trends Cell Biol. Author manuscript; available in PMC 2014 Aug 1.
Published in final edited form as: Trends Cell Biol. 2013 Aug; 23(8): 365–373. Published online 2013 Apr 11. doi: 10.1016/j.tcb.2013.03.006
PMCID:
PMC3729607
AbstractArticlePDF–954K
17.
Regulation of Nuclear Import/Export of Carbohydrate Response Element-binding Protein (ChREBP): INTERACTION OF AN α-HELIX OF ChREBP WITH THE 14-3-3 PROTEINS AND REGULATION BY PHOSPHORYLATION
Haruhiko Sakiyama, R. Max Wynn, Wan-Ru Lee, Masashi Fukasawa, Hiroyuki Mizuguchi, Kevin H. Gardner, Joyce J. Repa, Kosaku Uyeda
J Biol Chem. 2008 Sep 5; 283(36): 24899–24908. doi: 10.1074/jbc.M804308200
PMCID:
PMC3259841
AbstractArticlePDF–481K
18.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
19.
Nucleocytoplasmic Shuttling of Dysbindin-1, a Schizophrenia-related Protein, Regulates Synapsin I Expression
Erkang Fei, Xiaochuan Ma, Cuiqing Zhu, Ting Xue, Jie Yan, Yuxia Xu, Jiangning Zhou, Guanghui Wang
J Biol Chem. 2010 Dec 3; 285(49): 38630–38640. Published online 2010 Oct 4. doi: 10.1074/jbc.M110.107912
PMCID:
PMC2992295
AbstractArticlePDF–1.2M
20.
A phosphatase cascade by which natural rewards and drugs of abuse regulate nucleosomal response in the mouse
Alexandre Stipanovich, Emmanuel Valjent, Miriam Matamales, Akinori Nishi, Jung-Hyuck Ahn, Matthieu Maroteaux, Jesus Bertran-Gonzalez-, Karen Brami-Cherrier, Hervé Enslen, Anne-Gaëlle Corbillé, Odile Filhol, Angus C. Nairn, Paul Greengard, Denis Hervé, Jean-Antoine Girault
Nature. Author manuscript; available in PMC 2009 Dec 20.
Published in final edited form as: Nature. 2008 Jun 12; 453(7197): 879–884. Published online 2008 May 21. doi: 10.1038/nature06994
PMCID:
PMC2796210
AbstractArticlePDF–2.0M

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