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Select item 105220211.

Notch pathway mutants do not equivalently perturb mouse embryonic retinal development

Bernadett Bosze, Julissa Suarez-Navarro, Illiana Cajias, Joseph A. Brzezinski IV, Nadean L. Brown

PLoS Genet. 2023 Sep; 19(9): e1010928. Published online 2023 Sep 26. doi: 10.1371/journal.pgen.1010928

PMCID:: PMC10522021

Abstract Article PDF–5.9M

Select item 103791332.

Nuclear Receptor Subfamily 2 Group E Member 3 (NR2E3): Role in Retinal Development and Disease

Maria Toms, Natasha Ward, Mariya Moosajee

Genes (Basel) 2023 Jul; 14(7): 1325. Published online 2023 Jun 23. doi: 10.3390/genes14071325

PMCID:: PMC10379133

Abstract Article PDF–4.4M

Select item 84635943.

In vivo analysis of onset and progression of retinal degeneration in the Nr2e3^rd7/rd7 mouse model of enhanced S-cone sensitivity syndrome

Giulia Venturini, Despina Kokona, Beatrice L. Steiner, Emanuele G. Bulla, Joel Jovanovic, Martin S. Zinkernagel, Pascal Escher

Sci Rep. 2021; 11: 19032. Published online 2021 Sep 24. doi: 10.1038/s41598-021-98271-7

Correction in:: Sci Rep. 2021; 11: 20668.

PMCID:: PMC8463594

Abstract Article PDF–6.2M

Select item 83866004.

Mice deficient in UXT exhibit retinitis pigmentosa-like features via aberrant autophagy activation

Mingyu Pan, Yue Yin, Xinxia Wang, Quanyi Wang, Lele Zhang, Haiyang Hu, Chen Wang

Autophagy. 2021; 17(8): 1873–1888. Published online 2020 Aug 2. doi: 10.1080/15548627.2020.1796015

PMCID:: PMC8386600

Abstract Article PDF–8.5M

Select item 78384185.

Absence of S100A4 in the mouse lens induces an aberrant retina-specific differentiation program and cataract

Rupalatha Maddala, Junyuan Gao, Richard T. Mathias, Tylor R. Lewis, Vadim Y. Arshavsky, Adriana Levine, Jonathan M. Backer, Anne R. Bresnick, Ponugoti V. Rao

Sci Rep. 2021; 11: 2203. Published online 2021 Jan 26. doi: 10.1038/s41598-021-81611-y

PMCID:: PMC7838418

Abstract Article PDF–6.5M

Select item 74832676.

Nr2e3 is a genetic modifier that rescues retinal degeneration and promotes homeostasis in multiple models of retinitis pigmentosa

Sujun Li, Shyamtanu Datta, Emily Brabbit, Zoe Love, Victoria Woytowicz, Kyle Flattery, Jessica Capri, Katie Yao, Siqi Wu, Michael Imboden, Arun Upadhyay, Rasappa Arumugham, Wallace B. Thoreson, Margaret M. DeAngelis, Neena B. Haider

Gene Ther. 2021; 28(5): 223–241. Published online 2020 Mar 2. doi: 10.1038/s41434-020-0134-z

Correction in:: Gene Ther. 2024; 31(11-12): 630–632.

PMCID:: PMC7483267

Abstract Article PDF–6.3M

Select item 74014437.

Cd9 Protects Photoreceptors from Injury and Potentiates Edn2 Expression

Toshiro Iwagawa, Yuko Aihara, Daisy Umutoni, Yukihiro Baba, Akira Murakami, Kenji Miyado, Sumiko Watanabe

Invest Ophthalmol Vis Sci. 2020 Mar; 61(3): 7. Published online 2020 Mar 9. doi: 10.1167/iovs.61.3.7

PMCID:: PMC7401443

Abstract Article PDF–5.0M

Select item 72270288.

Mouse Models of Inherited Retinal Degeneration with Photoreceptor Cell Loss

Gayle B. Collin, Navdeep Gogna, Bo Chang, Nattaya Damkham, Jai Pinkney, Lillian F. Hyde, Lisa Stone, Jürgen K. Naggert, Patsy M. Nishina, Mark P. Krebs

Cells. 2020 Apr; 9(4): 931. Published online 2020 Apr 10. doi: 10.3390/cells9040931

PMCID:: PMC7227028

Abstract Article PDF–5.4M

Select item 70606709.

Foxn4 is a temporal identity factor conferring mid/late-early retinal competence and involved in retinal synaptogenesis

Shuting Liu, Xiaoning Liu, Shengguo Li, Xiuting Huang, Haohua Qian, Kangxin Jin, Mengqing Xiang

Proc Natl Acad Sci U S A. 2020 Mar 3; 117(9): 5016–5027. Published online 2020 Feb 18. doi: 10.1073/pnas.1918628117

PMCID:: PMC7060670

Abstract Article PDF–4.2M

Select item 702899610.

Chromatin remodeling protein HELLS is critical for retinoblastoma tumor initiation and progression

Loredana Zocchi, Aditi Mehta, Stephanie C. Wu, Jie Wu, Yijun Gu, Jingtian Wang, Susie Suh, Robert C. Spitale, Claudia A. Benavente

Oncogenesis. 2020 Feb; 9(2): 25. Published online 2020 Feb 18. doi: 10.1038/s41389-020-0210-7

PMCID:: PMC7028996

Abstract Article PDF–1.3M

Select item 672519911.

The Rod Photoreceptor-Specific Nuclear Receptor Nr2e3 Represses Transcription of Multiple Cone-Specific Genes

Jichao Chen, Amir Rattner, Jeremy Nathans

J Neurosci. 2005 Jan 5; 25(1): 118–129. doi: 10.1523/JNEUROSCI.3571-04.2005

PMCID:: PMC6725199

Abstract Article PDF–1003K

Select item 672502312.

The Genomic Response to Retinal Disease and Injury: Evidence for Endothelin Signaling from Photoreceptors to Glia

Amir Rattner, Jeremy Nathans

J Neurosci. 2005 May 4; 25(18): 4540–4549. doi: 10.1523/JNEUROSCI.0492-05.2005

PMCID:: PMC6725023

Abstract Article PDF–507K

Select item 660792813.

Identification of Genes With Enriched Expression in Early Developing Mouse Cone Photoreceptors

Diego F. Buenaventura, Adrianne Corseri, Mark M. Emerson

Invest Ophthalmol Vis Sci. 2019 Jul; 60(8): 2787–2799. doi: 10.1167/iovs.19-26951

PMCID:: PMC6607928

Abstract Article PDF–4.3M

Select item 659387914.

NR2E3 is a key component in p53 activation by regulating a long noncoding RNA DINO in acute liver injuries

Tilak Khanal, Yuet-Kin Leung, Wang Jiang, Nicolai Timchenko, Shuk-Mei Ho, Kyounghyun Kim

FASEB J. 2019 Jul; 33(7): 8335–8348. Published online 2019 Apr 16. doi: 10.1096/fj.201801881RR

PMCID:: PMC6593879

Abstract Article

Select item 614339415.

Requirements for Neurogenin2 during mouse postnatal retinal neurogenesis

Angelica M. Kowalchuk, Kate A. Maurer, Farnaz Shoja-Taheri, Nadean L. Brown

Dev Biol. Author manuscript; available in PMC 2019 Oct 15.

Published in final edited form as: Dev Biol. 2018 Oct 15; 442(2): 220–235. Published online 2018 Jul 24. doi: 10.1016/j.ydbio.2018.07.020

PMCID:: PMC6143394

Abstract Article PDF–1.3M

Select item 614078516.

An FRMD4B variant suppresses dysplastic photoreceptor lesions in models of enhanced S-cone syndrome and of Nrl deficiency

Yang Kong, Lihong Zhao, Jeremy R Charette, Wanda L Hicks, Lisa Stone, Patsy M Nishina, Jürgen K Naggert

Hum Mol Genet. 2018 Oct 1; 27(19): 3340–3352. Published online 2018 Jun 27. doi: 10.1093/hmg/ddy238

PMCID:: PMC6140785

Abstract Article PDF–2.8M

Select item 569311117.

Small molecule Photoregulin3 prevents retinal degeneration in the Rho^P23H mouse model of retinitis pigmentosa

Paul A Nakamura, Andy A Shimchuk, Shibing Tang, Zhizhi Wang, Kole DeGolier, Sheng Ding, Thomas A Reh

eLife. 2017; 6: e30577. Published online 2017 Nov 17. doi: 10.7554/eLife.30577

PMCID:: PMC5693111

Abstract Article PDF–2.2M

Select item 562591418.

Samd7 is a cell type-specific PRC1 component essential for establishing retinal rod photoreceptor identity

Yoshihiro Omori, Shun Kubo, Tetsuo Kon, Mayu Furuhashi, Hirotaka Narita, Taro Kominami, Akiko Ueno, Ryotaro Tsutsumi, Taro Chaya, Haruka Yamamoto, Isao Suetake, Shinji Ueno, Haruhiko Koseki, Atsushi Nakagawa, Takahisa Furukawa

Proc Natl Acad Sci U S A. 2017 Sep 26; 114(39): E8264–E8273. Published online 2017 Sep 12. doi: 10.1073/pnas.1707021114