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Items: 1 to 20 of 28

1.
SMAD4 target genes are part of a transcriptional network that integrates the response to BMP and SHH signaling during early limb bud patterning
Julie Gamart, Iros Barozzi, Frédéric Laurent, Robert Reinhardt, Laurène Ramos Martins, Thomas Oberholzer, Axel Visel, Rolf Zeller, Aimée Zuniga
Development. 2021 Dec 1; 148(23): dev200182. Published online 2021 Dec 3. doi: 10.1242/dev.200182
PMCID:
PMC8714076
AbstractArticle
2.
Chronic Disruption of the Late Cholesterol Synthesis Leads to Female-Prevalent Liver Cancer
Kaja Blagotinšek Cokan, Žiga Urlep, Gregor Lorbek, Madlen Matz-Soja, Cene Skubic, Martina Perše, Jera Jeruc, Peter Juvan, Tadeja Režen, Damjana Rozman
Cancers (Basel) 2020 Nov; 12(11): 3302. Published online 2020 Nov 9. doi: 10.3390/cancers12113302
PMCID:
PMC7695248
AbstractArticlePDF–5.2M
3.
BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)
Kou Motani, Hidetaka Kosako
J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323
PMCID:
PMC7415991
AbstractArticlePDF–2.0M
4.
Retinoic acid-induced CYP51 nuclear translocation promotes meiosis prophase I process and is correlated to the expression of REC8 and STAG3 in mice
Xinyi Mu, Jia Wen, Qian Chen, Zhengpin Wang, Yijing Wang, Meng Guo, Yi Yang, JinRui Xu, Zhiqing Wei, Guoliang Xia, Mengye Yang, Chao Wang
Biol Open. 2018 Nov 15; 7(11): bio035626. Published online 2018 Nov 15. doi: 10.1242/bio.035626
PMCID:
PMC6262859
AbstractArticlePDF–19M
5.
Lanosterol modulates TLR4 mediated innate immune responses in macrophages
Elisa Araldi, Marta Fernández-Fuertes, Alberto Canfrán-Duque, Wenwen Tang, Gary W Cline, Julio Madrigal-Matute, Jordan S. Pober, Miguel A. Lasunción, Dianqing Wu, Carlos Fernández-Hernando, Yajaira Suárez
Cell Rep. Author manuscript; available in PMC 2017 Aug 11.
Published in final edited form as: Cell Rep. 2017 Jun 27; 19(13): 2743–2755. doi: 10.1016/j.celrep.2017.05.093
PMCID:
PMC5553565
AbstractArticlePDF–1.5M
6.
Normalization of Hepatic Homeostasis in the Npc1nmf164 Mouse Model of Niemann-Pick Type C Disease Treated with the Histone Deacetylase Inhibitor Vorinostat
Andrew B. Munkacsi, Natalie Hammond, Remy T. Schneider, Dinindu S. Senanayake, Katsumi Higaki, Kirill Lagutin, Stephen J. Bloor, Daniel S. Ory, Robert A. Maue, Fannie W. Chen, Antonio Hernandez-Ono, Nicole Dahlson, Joyce J. Repa, Henry N. Ginsberg, Yiannis A. Ioannou, Stephen L. Sturley
J Biol Chem. 2017 Mar 17; 292(11): 4395–4410. Published online 2016 Dec 28. doi: 10.1074/jbc.M116.770578
PMCID:
PMC5377760
AbstractArticlePDF–2.8M
7.
Disrupting Hepatocyte Cyp51 from Cholesterol Synthesis Leads to Progressive Liver Injury in the Developing Mouse and Decreases RORC Signalling
Žiga Urlep, Gregor Lorbek, Martina Perše, Jera Jeruc, Peter Juvan, Madlen Matz-Soja, Rolf Gebhardt, Ingemar Björkhem, Jason A. Hall, Richard Bonneau, Dan R. Littman, Damjana Rozman
Sci Rep. 2017; 7: 40775. Published online 2017 Jan 18. doi: 10.1038/srep40775
PMCID:
PMC5241696
AbstractArticlePDF–2.0M
8.
Mfsd2a Is a Transporter for the Essential ω-3 Fatty Acid Docosahexaenoic Acid (DHA) in Eye and Is Important for Photoreceptor Cell Development
Bernice H. Wong, Jia Pei Chan, Amaury Cazenave-Gassiot, Rebecca W. Poh, Juat Chin Foo, Dwight L. A. Galam, Sujoy Ghosh, Long N. Nguyen, Veluchamy A. Barathi, Sia W. Yeo, Chi D. Luu, Markus R. Wenk, David L. Silver
J Biol Chem. 2016 May 13; 291(20): 10501–10514. Published online 2016 Mar 22. doi: 10.1074/jbc.M116.721340
PMCID:
PMC4865901
AbstractArticlePDF–5.4M
9.
A compendium of expression patterns of cholesterol biosynthetic enzymes in the mouse embryo
Melda Şişecioğlu, Harun Budak, Lars Geffers, Murat Çankaya, Mehmet Çiftci, Christina Thaller, Gregor Eichele, Ömer İrfan Küfrevioğlu, Hasan Özdemir
J Lipid Res. 2015 Aug; 56(8): 1551–1559. doi: 10.1194/jlr.M059634
PMCID:
PMC4513996
AbstractArticlePDF–3.4M
10.
Lessons from Hepatocyte-Specific Cyp51 Knockout Mice: Impaired Cholesterol Synthesis Leads to Oval Cell-Driven Liver Injury
Gregor Lorbek, Martina Perše, Jera Jeruc, Peter Juvan, Francisco M. Gutierrez-Mariscal, Monika Lewinska, Rolf Gebhardt, Rok Keber, Simon Horvat, Ingemar Björkhem, Damjana Rozman
Sci Rep. 2015; 5: 8777. Published online 2015 Mar 5. doi: 10.1038/srep08777
PMCID:
PMC4350092
AbstractArticlePDF–8.1M
11.
Identification of Natural RORγ Ligands that Regulate the Development of Lymphoid Cells
Fabio R. Santori, Pengxiang Huang, Serge A. van de Pavert, Eugene F. Douglass, Jr, David J. Leaver, Brad A. Haubrich, Rok Keber, Gregor Lorbek, Tanja Konijn, Brittany N. Rosales, Simon Horvat, Damjana Rozman, Alain Rahier, Reina E. Mebius, Fraydoon Rastinejad, W. David Nes, Dan R. Littman
Cell Metab. Author manuscript; available in PMC 2016 Feb 3.
Published in final edited form as: Cell Metab. 2015 Feb 3; 21(2): 286–297. doi: 10.1016/j.cmet.2015.01.004
PMCID:
PMC4317570
AbstractArticlePDF–1.8M
12.
Hidden Disease Susceptibility and Sexual Dimorphism in the Heterozygous Knockout of Cyp51 from Cholesterol Synthesis
Monika Lewinska, Peter Juvan, Martina Perse, Jera Jeruc, Spela Kos, Gregor Lorbek, Ziga Urlep, Rok Keber, Simon Horvat, Damjana Rozman
PLoS One. 2014; 9(11): e112787. Published online 2014 Nov 13. doi: 10.1371/journal.pone.0112787
PMCID:
PMC4231084
AbstractArticlePDF–7.1M
13.
Male germ cell-specific knockout of cholesterogenic cytochrome P450 lanosterol 14α-demethylase (Cyp51)
Rok Keber, Jure Ačimovič, Gregor Majdič, Helena Motaln, Damjana Rozman, Simon Horvat
J Lipid Res. 2013 Jun; 54(6): 1653–1661. doi: 10.1194/jlr.M035717
PMCID:
PMC3646466
AbstractArticlePDF–994K
14.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
15.
Mouse Knockout of the Cholesterogenic Cytochrome P450 Lanosterol 14α-Demethylase (Cyp51) Resembles Antley-Bixler Syndrome
Rok Keber, Helena Motaln, Kay D. Wagner, Nataša Debeljak, Minoo Rassoulzadegan, Jure Ačimovič, Damjana Rozman, Simon Horvat
J Biol Chem. 2011 Aug 19; 286(33): 29086–29097. Published online 2011 Jun 25. doi: 10.1074/jbc.M111.253245
PMCID:
PMC3190716
AbstractArticlePDF–4.8M
16.
Three-dimensional visualisation of testis cord morphogenesis, a novel tubulogenic mechanism in development
Alexander N. Combes, Emmanuelle Lesieur, Vincent R. Harley, Andrew H. Sinclair, Melissa H. Little, Dagmar Wilhelm, Peter Koopman
Dev Dyn. Author manuscript; available in PMC 2011 Oct 9.
Published in final edited form as: Dev Dyn. 2009 May; 238(5): 1033–1041. doi: 10.1002/dvdy.21925
PMCID:
PMC3189492
AbstractArticlePDF–2.5M
17.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
18.
A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo
Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio
PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582
PMCID:
PMC3022534
AbstractArticlePDF–3.8M
19.
Statins Promote the Degradation of Extracellular Amyloid β-Peptide by Microglia via Stimulation of Exosome-associated Insulin-degrading Enzyme (IDE) Secretion
Irfan Y. Tamboli, Esther Barth, Leonie Christian, Martin Siepmann, Sathish Kumar, Sandesh Singh, Karen Tolksdorf, Michael T. Heneka, Dieter Lütjohann, Patrick Wunderlich, Jochen Walter
J Biol Chem. 2010 Nov 26; 285(48): 37405–37414. Published online 2010 Sep 28. doi: 10.1074/jbc.M110.149468
PMCID:
PMC2988346
AbstractArticlePDF–5.3M
20.
Differential expression and function of ABCG1 and ABCG4 during development and aging
Dragana D. Bojanic, Paul T. Tarr, Greg D. Gale, Desmond J. Smith, Dean Bok, Bryan Chen, Steven Nusinowitz, Anita Lövgren-Sandblom, Ingemar Björkhem, Peter A. Edwards
J Lipid Res. 2010 Jan; 51(1): 169–181. doi: 10.1194/jlr.M900250-JLR200
PMCID:
PMC2789777
AbstractArticlePDF–1.7M

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