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Items: 1 to 20 of 406

1.
Single-cell RNA transcriptomics in mice reveals embryonic origin of fibrosis due to maternal obesity
Md Nazmul Hossain, Yao Gao, Xinrui Li, Liang Zhao, Xiangdong Liu, Jeanene Marie de Avila, Mei-Jun Zhu, Min Du
eBioMedicine. 2024 Nov; 109: 105421. Published online 2024 Oct 30. doi: 10.1016/j.ebiom.2024.105421
PMCID:
PMC11565040
AbstractArticlePDF–4.9M
2.
Hydrogen sulfide inhibits skeletal muscle ageing by up‐regulating autophagy through promoting deubiquitination of adenosine 5’‐monophosphate (AMP)‐activated protein kinase α1 via ubiquitin specific peptidase 5
Jia‐He Yang, Jun Gao, Ya‐Qi E, Li‐Jie Jiao, Ren Wu, Qiu‐Yi Yan, Zi‐Yi Wei, Guo‐Liang Yan, Jin‐Long Liang, Hong‐Zhu Li
J Cachexia Sarcopenia Muscle. 2024 Oct; 15(5): 2118–2133. Published online 2024 Aug 27. doi: 10.1002/jcsm.13560
PMCID:
PMC11446701
AbstractArticlePDF–12M
3.
AMPK targets PDZD8 to trigger carbon source shift from glucose to glutamine
Mengqi Li, Yu Wang, Xiaoyan Wei, Wei-Feng Cai, Jianfeng Wu, Mingxia Zhu, Yongliang Wang, Yan-Hui Liu, Jinye Xiong, Qi Qu, Yan Chen, Xiao Tian, Luming Yao, Renxiang Xie, Xiaomin Li, Siwei Chen, Xi Huang, Cixiong Zhang, Changchuan Xie, Yaying Wu, Zheni Xu, Baoding Zhang, Bin Jiang, Zhi-Chao Wang, Qinxi Li, Gang Li, Shu-Yong Lin, Li Yu, Hai-Long Piao, Xianming Deng, Jiahuai Han, Chen-Song Zhang, Sheng-Cai Lin
Cell Res. 2024 Oct; 34(10): 683–706. Published online 2024 Jun 19. doi: 10.1038/s41422-024-00985-6
PMCID:
PMC11442470
AbstractArticlePDF–6.2M
4.
Apaf1-deficient cortical neurons exhibit defects in axonal outgrowth
Daniela De Zio, Francesca Molinari, Salvatore Rizza, Lucia Gatta, Maria Teresa Ciotti, Anna Maria Salvatore, Søs Grønbæk Mathiassen, Andrzej W. Cwetsch, Giuseppe Filomeni, Giuseppe Rosano, Elisabetta Ferraro
Cell Mol Life Sci. 2015 Nov; 72(21): 4173–4191. Published online 2015 May 15. doi: 10.1007/s00018-015-1927-x
PMCID:
PMC11113842
AbstractArticlePDF–1.8M
5.
A novel AMPK-dependent FoxO3A-SIRT3 intramitochondrial complex sensing glucose levels
Alessia Peserico, Fulvio Chiacchiera, Valentina Grossi, Antonio Matrone, Dominga Latorre, Marta Simonatto, Aurora Fusella, James G. Ryall, Lydia W. S. Finley, Marcia C. Haigis, Gaetano Villani, Pier Lorenzo Puri, Vittorio Sartorelli, Cristiano Simone
Cell Mol Life Sci. 2013 Jun; 70(11): 2015–2029. Published online 2013 Jan 3. doi: 10.1007/s00018-012-1244-6
PMCID:
PMC11113715
AbstractArticlePDF–1.3M
6.
SLC7A11-ROS/αKG-AMPK axis regulates liver inflammation through mitophagy and impairs liver fibrosis and NASH progression
Tingting Lv, Xiude Fan, Chang He, Suwei Zhu, Xiaofeng Xiong, Wei Yan, Mei Liu, Hongwei Xu, Ruihua Shi, Qin He
Redox Biol. 2024 Jun; 72: 103159. Published online 2024 Apr 16. doi: 10.1016/j.redox.2024.103159
PMCID:
PMC11047786
AbstractArticlePDF–22M
7.
Loss of AMPK activity induces organelle dysfunction and oxidative stress during oocyte aging
Lin-Lin Hu, Mei-Hua Liao, Ya-Xi Liu, Chun-Hua Xing, Lan-Lan Nong, Feng-Lian Yang, Shao-Chen Sun
Biol Direct. 2024; 19: 29. Published online 2024 Apr 23. doi: 10.1186/s13062-024-00471-4
PMCID:
PMC11036640
AbstractArticlePDF–11M
8.
The AMPK-related kinase NUAK1 controls cortical axons branching by locally modulating mitochondrial metabolic functions
Marine Lanfranchi, Sozerko Yandiev, Géraldine Meyer-Dilhet, Salma Ellouze, Martijn Kerkhofs, Raphael Dos Reis, Audrey Garcia, Camille Blondet, Alizée Amar, Anita Kneppers, Hélène Polvèche, Damien Plassard, Marc Foretz, Benoit Viollet, Kei Sakamoto, Rémi Mounier, Cyril F. Bourgeois, Olivier Raineteau, Evelyne Goillot, Julien Courchet
Nat Commun. 2024; 15: 2487. Published online 2024 Mar 21. doi: 10.1038/s41467-024-46146-6
PMCID:
PMC10958033
AbstractArticlePDF–5.0M
9.
Activity-dependent compartmentalization of dendritic mitochondria morphology through local regulation of fusion-fission balance in neurons in vivo
Daniel M. Virga, Stevie Hamilton, Bertha Osei, Abigail Morgan, Parker Kneis, Emiliano Zamponi, Natalie J. Park, Victoria L. Hewitt, David Zhang, Kevin C. Gonzalez, Fiona M. Russell, D. Grahame Hardie, Julien Prudent, Erik Bloss, Attila Losonczy, Franck Polleux, Tommy L. Lewis, Jr
Nat Commun. 2024; 15: 2142. Published online 2024 Mar 8. doi: 10.1038/s41467-024-46463-w
PMCID:
PMC10923867
AbstractArticlePDF–7.3M
10.
Endothelial H2S-AMPK dysfunction upregulates the angiocrine factor PAI-1 and contributes to lung fibrosis
Xiangqi Chen, Han Wang, Chuan Wu, Xiaoyan Li, Xiaojuan Huang, Yafeng Ren, Qiang Pu, Zhongwei Cao, Xiaoqiang Tang, Bi-Sen Ding
Redox Biol. 2024 Apr; 70: 103038. Published online 2024 Jan 11. doi: 10.1016/j.redox.2024.103038
PMCID:
PMC10811458
AbstractArticlePDF–14M
11.
AMPKα1 negatively regulates osteoclastogenesis and mitigates pathological bone loss
Mariana S.P. Ribeiro, Lucas G.R. Venturini, Cesar A. Speck-Hernandez, Paulo V.G. Alabarse, Thais Xavier, Thaise M. Taira, Letícia F. Duffles, Fernando Q. Cunha, Sandra Y. Fukada
J Biol Chem. 2023 Dec; 299(12): 105379. Published online 2023 Oct 21. doi: 10.1016/j.jbc.2023.105379
PMCID:
PMC10692901
AbstractArticlePDF–2.5M
12.
Constitutively activated AMPKα1 protects against skeletal aging in mice by promoting bone‐derived IGF‐1 secretion
Yiqi Yang, Kai Yuan, Yihao Liu, Qishan Wang, Yixuan Lin, Shengbing Yang, Kai Huang, Tianyou Kan, Yuxin Zhang, Mingming Xu, Zhifeng Yu, Qiming Fan, Yugang Wang, Hanjun Li, Tingting Tang
Cell Prolif. 2023 Oct; 56(10): e13476. Published online 2023 Apr 11. doi: 10.1111/cpr.13476
PMCID:
PMC10542616
AbstractArticlePDF–15M
13.
NLRP14 Safeguards Calcium Homeostasis via Regulating the K27 Ubiquitination of Nclx in Oocyte‐to‐Embryo Transition
Tie‐Gang Meng, Jia‐Ni Guo, Liu Zhu, Yike Yin, Feng Wang, Zhi‐Ming Han, Lei Lei, Xue‐Shan Ma, Yue Xue, Wei Yue, Xiao‐Qing Nie, Zheng‐Hui Zhao, Hong‐Yong Zhang, Si‐Min Sun, Ying‐Chun Ouyang, Yi Hou, Heide Schatten, Zhenyu Ju, Xiang‐Hong Ou, Zhen‐Bo Wang, Catherine C. L. Wong, Zhonghan Li, Qing‐Yuan Sun
Adv Sci (Weinh) 2023 Sep; 10(27): 2301940. Published online 2023 Jul 26. doi: 10.1002/advs.202301940
PMCID:
PMC10520637
AbstractArticlePDF–6.6M
14.
KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility
Juan Gu, Pingyang Ke, Haokun Guo, Jing Liu, Yan Liu, Xin Tian, Zhuo Huang, Xin Xu, Demei Xu, Yuanlin Ma, Xuefeng Wang, Fei Xiao
Cell Death Differ. 2023 Jul; 30(7): 1726–1741. Published online 2023 May 4. doi: 10.1038/s41418-023-01174-5
PMCID:
PMC10307852
AbstractArticlePDF–8.8M
15.
Downregulation of hepatic ceruloplasmin ameliorates NAFLD via SCO1-AMPK-LKB1 complex
Liping Xie, Yanmei Yuan, Simiao Xu, Sijia Lu, Jinyang Gu, Yanping Wang, Yibing Wang, Xianjing Zhang, Suzhen Chen, Jian Li, Junxi Lu, Honglin Sun, Ruixiang Hu, Hailong Piao, Wen Wang, Cunchuan Wang, Jing Wang, Na Li, Morris F. White, Liu Han, Weiping Jia, Ji Miao, Junli Liu
Cell Rep. Author manuscript; available in PMC 2023 May 2.
Published in final edited form as: Cell Rep. 2022 Oct 18; 41(3): 111498. doi: 10.1016/j.celrep.2022.111498
PMCID:
PMC10153649
AbstractArticlePDF–1.6M
16.
Alpha-SNAP (M105I) mutation promotes neuronal differentiation of neural stem/progenitor cells through overactivation of AMPK
Felipe A. Bustamante-Barrientos, Maxs Méndez-Ruette, Luis Molina, Tania Koning, Pamela Ehrenfeld, Carlos B. González, Ursula Wyneken, Roberto Henzi, Luis Federico Bátiz
Front Cell Dev Biol. 2023; 11: 1061777. Published online 2023 Apr 11. doi: 10.3389/fcell.2023.1061777
PMCID:
PMC10127105
AbstractArticlePDF–4.2M
17.
Monocytes re-enter the bone marrow during fasting and alter the host response to infection
Henrike Janssen, Florian Kahles, Dan Liu, Jeffrey Downey, Laura Koekkoek, Vladimir Roudko, Darwin D’Souza, Cameron S. McAlpine, Lennard Halle, Wolfram C. Poller, Christopher T. Chan, Shun He, John E. Mindur, Mate Kiss, Sumnima Singh, Atsushi Anzai, Yoshiko Iwamoto, Rainer H. Kohler, Kashish Chetal, Ruslan I. Sadreyev, Ralph Weissleder, Seunghee Kim-Schulze, Miriam Merad, Matthias Nahrendorf, Filip K. Swirski
Immunity. Author manuscript; available in PMC 2024 Apr 11.
Published in final edited form as: Immunity. 2023 Apr 11; 56(4): 783–796.e7. Published online 2023 Feb 23. doi: 10.1016/j.immuni.2023.01.024
PMCID:
PMC10101885
AbstractArticlePDF–2.5M
18.
Ssu72 phosphatase is essential for thermogenic adaptation by regulating cytosolic translation
Eun-Ji Park, Hyun-Soo Kim, Do-Hyoung Lee, Su-Min Kim, Joon-Sup Yoon, Ji-Min Lee, Se Jin Im, Ho Lee, Min-Woo Lee, Chang-Woo Lee
Nat Commun. 2023; 14: 1097. Published online 2023 Feb 25. doi: 10.1038/s41467-023-36836-y
PMCID:
PMC9968297
AbstractArticlePDF–4.4M
19.
AMPK regulates homeostasis of invasion and viability in trophoblasts by redirecting glucose metabolism: Implications for pre‐eclampsia
Ping Xu, Yangxi Zheng, Jiujiang Liao, Mingyu Hu, Yike Yang, Baozhen Zhang, Mark D. Kilby, Huijia Fu, Yamin Liu, Fumei Zhang, Liling Xiong, Xiyao Liu, Huili Jin, Yue Wu, Jiayu Huang, Tingli Han, Li Wen, Rufei Gao, Yong Fu, Xiujun Fan, Hongbo Qi, Philip N. Baker, Chao Tong
Cell Prolif. 2023 Feb; 56(2): e13358. Published online 2022 Dec 8. doi: 10.1111/cpr.13358
PMCID:
PMC9890534
AbstractArticlePDF–14M
20.
AMPK integrates metabolite and kinase-based immunometabolic control in macrophages
Iain R. Phair, Raid B. Nisr, Andrew J.M. Howden, Magdalena Sovakova, Noor Alqurashi, Marc Foretz, Douglas Lamont, Benoit Viollet, Graham Rena
Mol Metab. 2023 Feb; 68: 101661. Published online 2022 Dec 28. doi: 10.1016/j.molmet.2022.101661
PMCID:
PMC9842865
AbstractArticlePDF–3.1M

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