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Items: 1 to 20 of 49

1.
Chr21 protein–protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer’s disease
Julia Viard, Yann Loe-Mie, Rachel Daudin, Malik Khelfaoui, Christine Plancon, Anne Boland, Francisco Tejedor, Richard L Huganir, Eunjoon Kim, Makoto Kinoshita, Guofa Liu, Volker Haucke, Thomas Moncion, Eugene Yu, Valérie Hindie, Henri Bléhaut, Clotilde Mircher, Yann Herault, Jean-François Deleuze, Jean-Christophe Rain, Michel Simonneau, Aude-Marie Lepagnol-Bestel
Life Sci Alliance. 2022 Dec; 5(12): e202101205. Published online 2022 Aug 1. doi: 10.26508/lsa.202101205
PMCID:
PMC9348576
AbstractArticlePDF–3.0M
2.
The proximal proteome of 17 SARS-CoV-2 proteins links to disrupted antiviral signaling and host translation
Jordan M. Meyers, Muthukumar Ramanathan, Ronald L. Shanderson, Aimee Beck, Laura Donohue, Ian Ferguson, Margaret G. Guo, Deepti S. Rao, Weili Miao, David Reynolds, Xue Yang, Yang Zhao, Yen-Yu Yang, Catherine Blish, Yinsheng Wang, Paul A. Khavari
PLoS Pathog. 2021 Oct; 17(10): e1009412. Published online 2021 Oct 1. doi: 10.1371/journal.ppat.1009412
PMCID:
PMC8513853
AbstractArticlePDF–4.1M
3.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
4.
Impact of cytosine methylation on DNA binding specificities of human transcription factors
Yimeng Yin, Ekaterina Morgunova, Arttu Jolma, Eevi Kaasinen, Biswajyoti Sahu, Syed Khund-Sayeed, Pratyush K. Das, Teemu Kivioja, Kashyap Dave, Fan Zhong, Kazuhiro R. Nitta, Minna Taipale, Alexander Popov, Paul A. Ginno, Silvia Domcke, Jian Yan, Dirk Schübeler, Charles Vinson, Jussi Taipale
Science. Author manuscript; available in PMC 2021 Mar 30.
Published in final edited form as: Science. 2017 May 5; 356(6337): eaaj2239. doi: 10.1126/science.aaj2239
PMCID:
PMC8009048
AbstractArticlePDF–2.6M
5.
Reciprocal activation of HEY1 and NOTCH4 under SOX2 control promotes EMT in head and neck squamous cell carcinoma
Takahito Fukusumi, Theresa W. Guo, Shuling Ren, Sunny Haft, Chao Liu, Akihiro Sakai, Mizuo Ando, Yuki Saito, Sayed Sadat, Joseph A. Califano
Int J Oncol. 2021 Feb; 58(2): 226–237. Published online 2020 Dec 10. doi: 10.3892/ijo.2020.5156
PMCID:
PMC7864008
AbstractArticlePDF–1.3M
6.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
7.
MiR-769 Inhibits Colorectal Cancer Cell Proliferation and Invasion by Targeting HEY1
Chao Han, Yingming Song, Changhong Lian
Med Sci Monit. 2018; 24: 9232–9239. Published online 2018 Dec 19. doi: 10.12659/MSM.911663
PMCID:
PMC6320662
AbstractArticlePDF–1.6M
8.
The NOTCH4-HEY1 pathway induces epithelial mesenchymal transition in head and neck squamous cell carcinoma
Takahito Fukusumi, Theresa W Guo, Akihiro Sakai, Mizuo Ando, Shuling Ren, Sunny Haft, Chao Liu, Panomwat Amornphimoltham, J. Silvio Gutkind, Joseph A Califano
Clin Cancer Res. Author manuscript; available in PMC 2019 Feb 1.
Published in final edited form as: Clin Cancer Res. 2018 Feb 1; 24(3): 619–633. Published online 2017 Nov 16. doi: 10.1158/1078-0432.CCR-17-1366
PMCID:
PMC6171749
AbstractArticlePDF–1.3M
9.
Nuclear Factor I Represses the Notch Effector HEY1 in Glioblastoma
Miranda Brun, Saket Jain, Elizabeth A. Monckton, Roseline Godbout
Neoplasia. 2018 Oct; 20(10): 1023–1037. Published online 2018 Sep 6. doi: 10.1016/j.neo.2018.08.007
PMCID:
PMC6138789
AbstractArticlePDF–3.3M
10.
USP11 regulates PML stability to control Notch-induced malignancy in brain tumours
Hsin-Chieh Wu, Yu-Ching Lin, Cheng-Hsin Liu, Hsiang-Ching Chung, Ya-Ting Wang, Ya-Wen Lin, Hsin-I. Ma, Pang-Hsien Tu, Sean E. Lawler, Ruey-Hwa Chen
Nat Commun. 2014; 5: 3214. Published online 2014 Feb 3. doi: 10.1038/ncomms4214
Correction in:
Nat Commun. 2017; 8: 16167.
PMCID:
PMC5645609
AbstractArticlePDF–3.0M
11.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
12.
HEY1 functions are regulated by its phosphorylation at Ser-68
Irene López-Mateo, Amaia Arruabarrena-Aristorena, Cristina Artaza-Irigaray, Juan A. López, Enrique Calvo, Borja Belandia
Biosci Rep. 2016 Jun; 36(3): e00343. Prepublished online 2016 Apr 27. Published online 2016 Jun 3. doi: 10.1042/BSR20160123
PMCID:
PMC5293587
AbstractArticlePDF–1.8M
13.
Phosphorylation of the chromatin remodeling factor DPF3a induces cardiac hypertrophy through releasing HEY repressors from DNA
Huanhuan Cui, Jenny Schlesinger, Sophia Schoenhals, Martje Tönjes, Ilona Dunkel, David Meierhofer, Elena Cano, Kerstin Schulz, Michael F. Berger, Timm Haack, Salim Abdelilah-Seyfried, Martha L. Bulyk, Sascha Sauer, Silke R. Sperling
Nucleic Acids Res. 2016 Apr 7; 44(6): 2538–2553. Published online 2015 Nov 17. doi: 10.1093/nar/gkv1244
PMCID:
PMC4824069
AbstractArticlePDF–6.1M
14.
The BioPlex Network: A Systematic Exploration of the Human Interactome
Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2016 Jul 16.
Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043
PMCID:
PMC4617211
AbstractArticlePDF–2.2M
15.
C8orf4 negatively regulates self-renewal of liver cancer stem cells via suppression of NOTCH2 signalling
Pingping Zhu, Yanying Wang, Ying Du, Lei He, Guanling Huang, Geng Zhang, Xinlong Yan, Zusen Fan
Nat Commun. 2015; 6: 7122. Published online 2015 May 19. doi: 10.1038/ncomms8122
PMCID:
PMC4479000
AbstractArticlePDF–3.4M
16.
Hey bHLH Proteins Interact with a FBXO45 Containing SCF Ubiquitin Ligase Complex and Induce Its Translocation into the Nucleus
Daniela Salat, Anja Winkler, Henning Urlaub, Manfred Gessler
PLoS One. 2015; 10(6): e0130288. Published online 2015 Jun 12. doi: 10.1371/journal.pone.0130288
PMCID:
PMC4466309
AbstractArticlePDF–7.8M
17.
Hairy/enhancer-of-split related with YRPW motif protein 1 promotes osteosarcoma metastasis via matrix metallopeptidase 9 expression
A Tsuru, T Setoguchi, Y Matsunoshita, H Nagao-Kitamoto, S Nagano, M Yokouchi, S Maeda, Y Ishidou, T Yamamoto, S Komiya
Br J Cancer. 2015 Mar 31; 112(7): 1232–1240. Published online 2015 Mar 5. doi: 10.1038/bjc.2015.84
PMCID:
PMC4385965
AbstractArticlePDF–1.4M
18.
Serum Induces Transcription of Hey1 and Hey2 Genes by Alk1 but Not Notch Signaling in Endothelial Cells
Kerstin Wöltje, Markus Jabs, Andreas Fischer
PLoS One. 2015; 10(3): e0120547. Published online 2015 Mar 23. doi: 10.1371/journal.pone.0120547
PMCID:
PMC4370690
AbstractArticlePDF–1.4M
19.
Prostate tumor OVerexpressed-1 (PTOV1) down-regulates HES1 and HEY1 notch targets genes and promotes prostate cancer progression
Lide Alaña, Marta Sesé, Verónica Cánovas, Yolanda Punyal, Yolanda Fernández, Ibane Abasolo, Inés de Torres, Cristina Ruiz, Lluís Espinosa, Anna Bigas, Santiago Ramón y Cajal, Pedro L Fernández, Florenci Serras, Montserrat Corominas, Timothy M Thomson, Rosanna Paciucci
Mol Cancer. 2014; 13: 74. Published online 2014 Mar 31. doi: 10.1186/1476-4598-13-74
PMCID:
PMC4021398
AbstractArticlePDF–3.2M
20.
Role of HERP and a HERP-related Protein in HRD1-dependent Protein Degradation at the Endoplasmic Reticulum
Chih-Hsiang Huang, Yue-Ru Chu, Yihong Ye, Xin Chen
J Biol Chem. 2014 Feb 14; 289(7): 4444–4454. Published online 2013 Dec 23. doi: 10.1074/jbc.M113.519561
PMCID:
PMC3924306
AbstractArticlePDF–2.0M

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