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Select item 114015081.

SMYD5 is a regulator of the mild hypothermia response

Salvor Rafnsdottir, Kijin Jang, Sara Tholl Halldorsdottir, Meghna Vinod, Arnhildur Tomasdottir, Katrin Möller, Katrin Halldorsdottir, Tinna Reynisdottir, Laufey Halla Atladottir, Kristin Elisabet Allison, Kevin Ostacolo, Jin He, Li Zhang, Frances J. Northington, Erna Magnusdottir, Raul Chavez-Valdez, Kimberley Jade Anderson, Hans Tomas Bjornsson

Cell Rep. Author manuscript; available in PMC 2024 Sep 14.

Published in final edited form as: Cell Rep. 2024 Aug 27; 43(8): 114554. Published online 2024 Jul 30. doi: 10.1016/j.celrep.2024.114554

PMCID:: PMC11401508

Abstract Article PDF–2.7M

Select item 113690922.

SMYD5 is a ribosomal methyltransferase that catalyzes RPL40 lysine methylation to enhance translation output and promote hepatocellular carcinoma

Bisi Miao, Ling Ge, Chenxi He, Xinghao Wang, Jibo Wu, Xiang Li, Kun Chen, Jinkai Wan, Shenghui Xing, Lingnan Ren, Zhennan Shi, Shengnan Liu, Yajun Hu, Jiajia Chen, Yanyan Yu, Lijian Feng, Natasha M. Flores, Zhihui Liang, Xinyi Xu, Ruoxin Wang, Jian Zhou, Jia Fan, Bin Xiang, En Li, Yuanhui Mao, Jingdong Cheng, Kehao Zhao, Pawel K. Mazur, Jiabin Cai, Fei Lan

Cell Res. 2024 Sep; 34(9): 648–660. Published online 2024 Aug 5. doi: 10.1038/s41422-024-01013-3

PMCID:: PMC11369092

Abstract Article PDF–3.7M

Select item 109176603.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 92499194.

Epithelial SMYD5 Exaggerates IBD by Down-regulating Mitochondrial Functions via Post-Translational Control of PGC-1α Stability

Yuning Hou, Xiaonan Sun, Pooneh Tavakoley Gheinani, Xiaoqing Guan, Shaligram Sharma, Yu Zhou, Chengliu Jin, Zhe Yang, Anjaparavanda P. Naren, Jun Yin, Timothy L. Denning, Andrew T. Gewirtz, Yuan Liu, Zhonglin Xie, Chunying Li

Cell Mol Gastroenterol Hepatol. 2022; 14(2): 375–403. Published online 2022 May 25. doi: 10.1016/j.jcmgh.2022.05.006

PMCID:: PMC9249919

Abstract Article PDF–8.3M

Select item 91845755.

SMYD5 catalyzes histone H3 lysine 36 trimethylation at promoters

Yanjun Zhang, Yuan Fang, Yin Tang, Shixun Han, Junqi Jia, Xinyi Wan, Jiaqi Chen, Ying Yuan, Bin Zhao, Dong Fang

Nat Commun. 2022; 13: 3190. Published online 2022 Jun 9. doi: 10.1038/s41467-022-30940-1

PMCID:: PMC9184575

Abstract Article PDF–5.1M

Select item 88966566.

SMYD5 is a histone H3-specific methyltransferase mediating mono-methylation of histone H3 lysine 36 and 37

Mohammad B. Aljazi, Yuen Gao, Yan Wu, Jin He

Biochem Biophys Res Commun. Author manuscript; available in PMC 2023 Apr 9.

Published in final edited form as: Biochem Biophys Res Commun. 2022 Apr 9; 599: 142–147. Published online 2022 Feb 12. doi: 10.1016/j.bbrc.2022.02.043

PMCID:: PMC8896656

Abstract Article PDF–735K

Select item 64595107.

Mouse screen reveals multiple new genes underlying mouse and human hearing loss

Neil J. Ingham, Selina A. Pearson, Valerie E. Vancollie, Victoria Rook, Morag A. Lewis, Jing Chen, Annalisa Buniello, Elisa Martelletti, Lorenzo Preite, Chi Chung Lam, Felix D. Weiss, Zӧe Powis, Pim Suwannarat, Christopher J. Lelliott, Sally J. Dawson, Jacqueline K. White, Karen P. Steel

PLoS Biol. 2019 Apr; 17(4): e3000194. Published online 2019 Apr 11. doi: 10.1371/journal.pbio.3000194

PMCID:: PMC6459510

Abstract Article PDF–5.1M

Select item 58044828.

SMYD5 controls heterochromatin and chromosome integrity during embryonic stem cell differentiation

Benjamin L. Kidder, Runsheng He, Darawalee Wangsa, Hesed M. Padilla-Nash, M. Margarida Bernardo, Shijie Sheng, Thomas Ried, Keji Zhao

Cancer Res. Author manuscript; available in PMC 2018 Dec 1.

Published in final edited form as: Cancer Res. 2017 Dec 1; 77(23): 6729–6745. Published online 2017 Sep 26. doi: 10.1158/0008-5472.CAN-17-0828

PMCID:: PMC5804482

Abstract Article PDF–1.6M

Select item 57161829.

An efficient method for generation of bi-allelic null mutant mouse embryonic stem cells and its application for investigating epigenetic modifiers

Cynthia L. Fisher, Hendrik Marks, Lily Ting-yin Cho, Robert Andrews, Sam Wormald, Thomas Carroll, Vivek Iyer, Peri Tate, Barry Rosen, Hendrik G. Stunnenberg, Amanda G. Fisher, William C. Skarnes

Nucleic Acids Res. 2017 Dec 1; 45(21): e174. Published online 2017 Sep 13. doi: 10.1093/nar/gkx811

PMCID:: PMC5716182

Abstract Article PDF–3.8M

Select item 532430810.

SMYD5 regulates H4K20me3-marked heterochromatin to safeguard ES cell self-renewal and prevent spurious differentiation

Benjamin L. Kidder, Gangqing Hu, Kairong Cui, Keji Zhao

Epigenetics Chromatin. 2017; 10: 8. Published online 2017 Feb 23. doi: 10.1186/s13072-017-0115-7

PMCID:: PMC5324308

Abstract Article PDF–3.1M

Select item 416216811.

Role of the ANKMY2-FKBP38 Axis in Regulation of the Sonic Hedgehog (Shh) Signaling Pathway

Shotaro Saita, Michiko Shirane, Tohru Ishitani, Nobuyuki Shimizu, Keiichi I. Nakayama

J Biol Chem. 2014 Sep 12; 289(37): 25639–25654. Published online 2014 Jul 30. doi: 10.1074/jbc.M114.558635

PMCID:: PMC4162168

Abstract Article PDF–5.4M

Select item 374561012.

Molecular Characterization of Mutant Mouse Strains Generated from the EUCOMM/KOMP-CSD ES Cell Resource

Edward Ryder, Diane Gleeson, Debarati Sethi, Sapna Vyas, Evelina Miklejewska, Priya Dalvi, Bishoy Habib, Ross Cook, Matthew Hardy, Kalpesh Jhaveri, Joanna Bottomley, Hannah Wardle-Jones, James N. Bussell, Richard Houghton, Jennifer Salisbury, William C. Skarnes, Sanger Mouse Genetics Project, Ramiro Ramirez-Solis

Mamm Genome. 2013; 24(7): 286–294. Published online 2013 Aug 4. doi: 10.1007/s00335-013-9467-x

PMCID:: PMC3745610

Abstract Article PDF–353K

Select item 357241013.

A conditional knockout resource for the genome–wide study of mouse gene function

William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley

Nature. Author manuscript; available in PMC 2013 Feb 14.

Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163

PMCID:: PMC3572410

Abstract Article PDF–1.1M

Select item 347235914.

Control of Pro-Inflammatory Gene Programs by Regulated Trimethylation and Demethylation of Histone H4K20

Joshua D. Stender, Gabriel Pascual, Wen Liu, Minna U. Kaikkonen, Kevin Do, Nathanael J Spann, Michael Boutros, Norbert Perrimon, Michael G. Rosenfeld, Christopher K. Glass

Mol Cell. Author manuscript; available in PMC 2013 Oct 12.

Published in final edited form as: Mol Cell. 2012 Oct 12; 48(1): 28–38. Published online 2012 Aug 23. doi: 10.1016/j.molcel.2012.07.020

PMCID:: PMC3472359

Abstract Article PDF–1.5M

Select item 317805915.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 302253416.

A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo

Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio

PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582

PMCID:: PMC3022534

Abstract Article PDF–3.8M

Select item 284003417.

Cardiac Deletion of Smyd2 Is Dispensable for Mouse Heart Development

Florian Diehl, Mark A. Brown, Machteld J. van Amerongen, Tatyana Novoyatleva, Astrid Wietelmann, June Harriss, Fulvia Ferrazzi, Thomas Böttger, Richard P. Harvey, Philip W. Tucker, Felix B. Engel

PLoS One. 2010; 5(3): e9748. Published online 2010 Mar 17. doi: 10.1371/journal.pone.0009748

PMCID:: PMC2840034

Abstract Article PDF–3.7M

Select item 255627018.

Large-scale gene trapping in C57BL/6N mouse embryonic stem cells

Gwenn M. Hansen, Diane C. Markesich, Michael B. Burnett, Qichao Zhu, Karen M. Dionne, Lizabeth J. Richter, Richard H. Finnell, Arthur T. Sands, Brian P. Zambrowicz, Alejandro Abuin

Genome Res. 2008 Oct; 18(10): 1670–1679. doi: 10.1101/gr.078352.108

PMCID:: PMC2556270

Abstract Article PDF–493K

Select item 141356819.

BGEM: An In Situ Hybridization Database of Gene Expression in the Embryonic and Adult Mouse Nervous System

Susan Magdaleno, Patricia Jensen, Craig L Brumwell, Anna Seal, Karen Lehman, Andrew Asbury, Tony Cheung, Tommie Cornelius, Diana M Batten, Christopher Eden, Shannon M Norland, Dennis S Rice, Nilesh Dosooye, Sundeep Shakya, Perdeep Mehta, Tom Curran

PLoS Biol. 2006 Apr; 4(4): e86. Published online 2006 Mar 28. doi: 10.1371/journal.pbio.0040086

PMCID:: PMC1413568

Article PDF–99K

Select item 52892820.

The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)

Genome Res. 2004 Oct; 14(10b): 2121–2127. doi: 10.1101/gr.2596504

Correction in:: Genome Res. 2006 Jun; 16(6): 804.

PMCID:: PMC528928

Abstract Article PDF–140K

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