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Select item 116690681.

Time‐of‐day control of mitochondria regulates NLRP3 inflammasome activation in macrophages

James R. O'Siorain, Shannon L. Cox, Cloé Payet, Frances K. Nally, Yan He, Tabea T. Drewinksi, Oran D. Kennedy, Jennifer K. Dowling, Mark Mellett, James O. Early, Annie M. Curtis

FASEB J. 2024 Dec 31; 38(24): e70235. Published online 2024 Dec 17. doi: 10.1096/fj.202400508RR

PMCID:: PMC11669068

Abstract Article PDF–3.3M

Select item 116318842.

The circadian clock gene BMAL1 modulates autoimmunity features in lupus

Shuichiro Nakabo, Donavon Sandoval-Heglund, Norio Hanata, Stephen Brooks, Victoria Hoffmann, Mingzeng Zhang, William Ambler, Zerai Manna, Elaine Poncio, Sarfaraz Hasni, Shamima Islam, Stefania Dell’Orso, Mariana J. Kaplan

Front Immunol. 2024; 15: 1465185. Published online 2024 Nov 27. doi: 10.3389/fimmu.2024.1465185

PMCID:: PMC11631884

Abstract Article PDF–4.9M

Select item 116010983.

Hepatocyte Period 1 dictates oxidative substrate selection independent of the core circadian clock

Jiameng Sun, Yiming Zhang, Joshua A. Adams, Cassandra B. Higgins, Shannon C. Kelly, Hao Zhang, Kevin Y. Cho, Ulysses G. Johnson, Benjamin M. Swarts, Shun-lchi Wada, Gary J. Patti, Leah P. Shriver, Brian N. Finck, Erik D. Herzog, Brian J. DeBosch

Cell Rep. Author manuscript; available in PMC 2024 Nov 27.

Published in final edited form as: Cell Rep. 2024 Oct 22; 43(10): 114865. Published online 2024 Oct 16. doi: 10.1016/j.celrep.2024.114865

PMCID:: PMC11601098

Abstract Article PDF–2.9M

Select item 115505904.

Core circadian transcription factor Bmal1 mediates β cell response and recovery from pro-inflammatory injury

Kuntol Rakshit, Matthew R. Brown, Naureen Javeed, Jeong-Heon Lee, Tamas Ordog, Aleksey V. Matveyenko

iScience. 2024 Nov 15; 27(11): 111179. Published online 2024 Oct 16. doi: 10.1016/j.isci.2024.111179

PMCID:: PMC11550590

Abstract Article PDF–6.1M

Select item 115494075.

Circadian rhythms of macrophages are altered by the acidic tumor microenvironment

Amelia M Knudsen-Clark, Daniel Mwangi, Juliana Cazarin, Kristina Morris, Cameron Baker, Lauren M Hablitz, Matthew N McCall, Minsoo Kim, Brian J Altman

EMBO Rep. 2024 Nov; 25(11): 5080–5112. Published online 2024 Oct 16. doi: 10.1038/s44319-024-00288-2

PMCID:: PMC11549407

Abstract Article PDF–5.9M

Select item 114461536.

Cell-specific regulation of the circadian clock by BMAL1 in the paraventricular nucleus: Implications for regulation of systemic biological rhythms

Rachel Van Drunen, Yulin Dai, Haichao Wei, Baharan Fekry, Sina Noori, Samay Shivshankar, Rafael Bravo, Zhongming Zhao, Seung-hee Yoo, Nicholas Justice, Jia Qian Wu, Qingchun Tong, Kristin Eckel-Mahan

Cell Rep. Author manuscript; available in PMC 2024 Oct 2.

Published in final edited form as: Cell Rep. 2024 Jul 23; 43(7): 114380. Published online 2024 Jun 26. doi: 10.1016/j.celrep.2024.114380

PMCID:: PMC11446153

Abstract Article PDF–2.5M

Select item 114304767.

Disruption of the intestinal clock drives dysbiosis and impaired barrier function in colorectal cancer

Rachel C. Fellows, Sung Kook Chun, Natalie Larson, Bridget M. Fortin, Alisa L. Mahieu, Wei A. Song, Marcus M. Seldin, Nicholas R. Pannunzio, Selma Masri

Sci Adv. 2024 Sep 27; 10(39): eado1458. Published online 2024 Sep 27. doi: 10.1126/sciadv.ado1458

PMCID:: PMC11430476

Abstract Article PDF–5.1M

Select item 113440808.

Prefrontal cortex molecular clock modulates development of depression-like phenotype and rapid antidepressant response in mice

David H. Sarrazin, Wilf Gardner, Carole Marchese, Martin Balzinger, Chockalingam Ramanathan, Marion Schott, Stanislav Rozov, Maxime Veleanu, Stefan Vestring, Claus Normann, Tomi Rantamäki, Benedicte Antoine, Michel Barrot, Etienne Challet, Patrice Bourgin, Tsvetan Serchov

Nat Commun. 2024; 15: 7257. Published online 2024 Aug 23. doi: 10.1038/s41467-024-51716-9

PMCID:: PMC11344080

Abstract Article PDF–4.4M

Select item 112947289.

Skeletal muscle BMAL1 is necessary for transcriptional adaptation of local and peripheral tissues in response to endurance exercise training

Mark R. Viggars, Hannah E. Berko, Stuart J. Hesketh, Christopher A. Wolff, Miguel A. Gutierrez-Monreal, Ryan A. Martin, Isabel G. Jennings, Zhiguang Huo, Karyn A. Esser

Mol Metab. 2024 Aug; 86: 101980. Published online 2024 Jun 29. doi: 10.1016/j.molmet.2024.101980

PMCID:: PMC11294728

Abstract Article PDF–5.8M

Select item 1129188610.

Targeting the intestinal circadian clock by meal timing ameliorates gastrointestinal inflammation

Yunhui Niu, Marjolein Heddes, Baraa Altaha, Michael Birkner, Karin Kleigrewe, Chen Meng, Dirk Haller, Silke Kiessling

Cell Mol Immunol. 2024 Aug; 21(8): 842–855. Published online 2024 Jun 25. doi: 10.1038/s41423-024-01189-z

PMCID:: PMC11291886

Abstract Article PDF–5.5M

Select item 1128582211.

Fibroblast-like synoviocytes orchestrate daily rhythmic inflammation in arthritis

Polly Downton, Suzanna H. Dickson, David W. Ray, David A. Bechtold, Julie E. Gibbs

Open Biol. 2024 Jul; 14(7): 240089. Published online July 10, 2024. doi: 10.1098/rsob.240089

PMCID:: PMC11285822

Abstract Article PDF–19M

Select item 1126433112.

Circadian-clock-controlled endocrine and cytokine signals regulate multipotential innate lymphoid cell progenitors in the bone marrow

Qingyang Liu, Shams Tabrez, Patrick Niekamp, Chang H. Kim

Cell Rep. Author manuscript; available in PMC 2024 Jul 23.

Published in final edited form as: Cell Rep. 2024 May 28; 43(5): 114200. Published online 2024 May 7. doi: 10.1016/j.celrep.2024.114200

PMCID:: PMC11264331

Abstract Article PDF–2.9M

Select item 1121364613.

BMAL1 sex‐specific effects in the neonatal mouse airway exposed to moderate hyperoxia

Colleen M. Bartman, Lisa Nesbitt, Kenge K. Lee, Latifa Khalfaoui, Yun‐Hua Fang, Christina M. Pabelick, Y. S. Prakash

Physiol Rep. 2024 Jul; 12(13): e16122. Published online 2024 Jun 28. doi: 10.14814/phy2.16122

PMCID:: PMC11213646

Abstract Article PDF–5.9M

Select item 1119127514.

Sleep deprivation induces corneal endothelial dysfunction by downregulating Bmal1

Yani Wang, Qun Wang, Shengqian Dou, Qingjun Zhou, Lixin Xie

BMC Ophthalmol. 2024; 24: 268. Published online 2024 Jun 21. doi: 10.1186/s12886-024-03524-4

Correction in:: BMC Ophthalmol. 2024; 24: 274.

PMCID:: PMC11191275

Abstract Article PDF–7.2M

Select item 1118310415.

Circadian rhythm disruption-mediated downregulation of Bmal1 exacerbates DSS-induced colitis by impairing intestinal barrier

Zhongchao Zhang, Wanneng Li, Xu Han, Dean Tian, Wei Yan, Mei Liu, Li Cao

Front Immunol. 2024; 15: 1402395. Published online 2024 Jun 4. doi: 10.3389/fimmu.2024.1402395

PMCID:: PMC11183104

Abstract Article PDF–12M

Select item 1117255516.

Metabolic Profile and Lipid Metabolism Phenotype in Mice with Conditional Deletion of Hepatic BMAL1

Weijia Gu, Ting Li, Yuxin Huang, Ruiqing Wang, Lu Zhang, Rucheng Chen, Ran Li, Cuiqing Liu

Int J Mol Sci. 2024 Jun; 25(11): 6070. Published online 2024 May 31. doi: 10.3390/ijms25116070

PMCID:: PMC11172555

Abstract Article PDF–2.5M

Select item 1116175617.

Phosphorylation of DNA-binding domains of CLOCK–BMAL1 complex for PER-dependent inhibition in circadian clock of mammalian cells

Yuta Otobe, Eui Min Jeong, Shunsuke Ito, Yuta Shinohara, Nobuhiro Kurabayashi, Atsu Aiba, Yoshitaka Fukada, Jae Kyoung Kim, Hikari Yoshitane

Proc Natl Acad Sci U S A. 2024 Jun 4; 121(23): e2316858121. Published online 2024 May 28. doi: 10.1073/pnas.2316858121

PMCID:: PMC11161756

Abstract Article PDF–4.4M

Select item 1104707818.

Bmal1 integrates circadian function and temperature sensing in the suprachiasmatic nucleus

Marieke M. B. Hoekstra, Natalie Ness, Aina Badia-Soteras, Marco Brancaccio

Proc Natl Acad Sci U S A. 2024 Apr 23; 121(17): e2316646121. Published online 2024 Apr 16. doi: 10.1073/pnas.2316646121

PMCID:: PMC11047078

Abstract Article PDF–2.2M

Select item 1094633219.

High-frequency neural activity dysregulation is associated with sleep and psychiatric disorders in BMAL1-deficient animal models

Yu Sun, Mingzhu Zhong, Niannian Xu, Xueting Zhang, Huanhuan Sun, Yan Wang, Yong Lu, Yanhong Nie, Qing Li, Qiang Sun, Jian Jiang, Yun-Chi Tang, Hung-Chun Chang

iScience. 2024 Apr 19; 27(4): 109381. Published online 2024 Mar 1. doi: 10.1016/j.isci.2024.109381