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Select item 103078521.

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility

Juan Gu, Pingyang Ke, Haokun Guo, Jing Liu, Yan Liu, Xin Tian, Zhuo Huang, Xin Xu, Demei Xu, Yuanlin Ma, Xuefeng Wang, Fei Xiao

Cell Death Differ. 2023 Jul; 30(7): 1726–1741. Published online 2023 May 4. doi: 10.1038/s41418-023-01174-5

PMCID:: PMC10307852

Abstract Article PDF–8.8M

Select item 102089582.

Impaired OTUD7A-dependent Ankyrin regulation mediates neuronal dysfunction in mouse and human models of the 15q13.3 microdeletion syndrome

Brianna K. Unda, Leon Chalil, Sehyoun Yoon, Savannah Kilpatrick, Courtney Irwin, Sansi Xing, Nadeem Murtaza, Anran Cheng, Chad Brown, Alexandria Afonso, Elizabeth McCready, Gabriel M. Ronen, Jennifer Howe, Aurélie Caye-Eude, Alain Verloes, Brad W. Doble, Laurence Faivre, Antonio Vitobello, Stephen W. Scherer, Yu Lu, Peter Penzes, Karun K. Singh

Mol Psychiatry. 2023; 28(4): 1747–1769. Published online 2023 Jan 6. doi: 10.1038/s41380-022-01937-5

PMCID:: PMC10208958

Abstract Article PDF–7.0M

Select item 99927373.

Dlg1 deletion in microglia ameliorates chronic restraint stress induced mice depression-like behavior

Xiaoheng Li, Zhixin Peng, Lingling Jiang, Ping Zhang, Pin Yang, Zengqiang Yuan, Jinbo Cheng

Front Pharmacol. 2023; 14: 1124845. Published online 2023 Feb 22. doi: 10.3389/fphar.2023.1124845

PMCID:: PMC9992737

Abstract Article PDF–2.7M

Select item 99382164.

Rescue of neuropsychiatric phenotypes in a mouse model of 16p11.2 duplication syndrome by genetic correction of an epilepsy network hub

Marc P. Forrest, Marc Dos Santos, Nicolas H. Piguel, Yi-Zhi Wang, Nicole A. Hawkins, Vikram A. Bagchi, Leonardo E. Dionisio, Sehyoun Yoon, Dina Simkin, Maria Dolores Martin-de-Saavedra, Ruoqi Gao, Katherine E. Horan, Alfred L. George, Jr., Mark S. LeDoux, Jennifer A. Kearney, Jeffrey N. Savas, Peter Penzes

Nat Commun. 2023; 14: 825. Published online 2023 Feb 17. doi: 10.1038/s41467-023-36087-x

PMCID:: PMC9938216

Abstract Article PDF–5.3M

Select item 99225445.

A DLG1-ARHGAP31-CDC42 axis is essential for the intestinal stem cell response to fluctuating niche Wnt signaling

David Castillo-Azofeifa, Tomas Wald, Efren A. Reyes, Aaron Gallagher, Julia Schanin, Stephanie Vlachos, Nathalie Lamarche-Vane, Carolyn Bomidi, Sarah Blutt, Mary K. Estes, Todd Nystul, Ophir D. Klein

Cell Stem Cell. Author manuscript; available in PMC 2024 Feb 2.

Published in final edited form as: Cell Stem Cell. 2023 Feb 2; 30(2): 188–206.e6. Published online 2023 Jan 13. doi: 10.1016/j.stem.2022.12.008

PMCID:: PMC9922544

Abstract Article PDF–2.8M

Select item 93485766.

Chr21 protein–protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer’s disease

Julia Viard, Yann Loe-Mie, Rachel Daudin, Malik Khelfaoui, Christine Plancon, Anne Boland, Francisco Tejedor, Richard L Huganir, Eunjoon Kim, Makoto Kinoshita, Guofa Liu, Volker Haucke, Thomas Moncion, Eugene Yu, Valérie Hindie, Henri Bléhaut, Clotilde Mircher, Yann Herault, Jean-François Deleuze, Jean-Christophe Rain, Michel Simonneau, Aude-Marie Lepagnol-Bestel

Life Sci Alliance. 2022 Dec; 5(12): e202101205. Published online 2022 Aug 1. doi: 10.26508/lsa.202101205

PMCID:: PMC9348576

Abstract Article PDF–3.0M

Select item 91173337.

Novel role of the synaptic scaffold protein Dlgap4 in ventricular surface integrity and neuronal migration during cortical development

Delfina M. Romero, Karine Poirier, Richard Belvindrah, Imane Moutkine, Anne Houllier, Anne-Gaëlle LeMoing, Florence Petit, Anne Boland, Stephan C. Collins, Mariano Soiza-Reilly, Binnaz Yalcin, Jamel Chelly, Jean-François Deleuze, Nadia Bahi-Buisson, Fiona Francis

Nat Commun. 2022; 13: 2746. Published online 2022 May 18. doi: 10.1038/s41467-022-30443-z

PMCID:: PMC9117333

Abstract Article PDF–16M

Select item 86433778.

Dlg1 Knockout Inhibits Microglial Activation and Alleviates Lipopolysaccharide-Induced Depression-Like Behavior in Mice

Zhixin Peng, Xiaoheng Li, Jun Li, Yuan Dong, Yuhao Gao, Yajin Liao, Meichen Yan, Zengqiang Yuan, Jinbo Cheng

Neurosci Bull. 2021 Dec; 37(12): 1671–1682. Published online 2021 Sep 6. doi: 10.1007/s12264-021-00765-x

PMCID:: PMC8643377

Abstract Article PDF–2.3M

Select item 83235929.

Dlg1 Maintains Dendritic Cell Function by Securing Voltage-Gated K⁺ Channel Integrity

Xuejiao Dong, Lisi Wei, Xueheng Guo, Zhiyong Yang, Chuan Wu, Peiyu Li, Lu Lu, Hai Qi, Yan Shi, Xiaoyu Hu, Li Wu, Liangyi Chen, Wanli Liu

J Immunol. Author manuscript; available in PMC 2021 Jul 30.

Published in final edited form as: J Immunol. 2019 Jun 1; 202(11): 3187–3197. Published online 2019 Apr 26. doi: 10.4049/jimmunol.1900089

PMCID:: PMC8323592

Abstract Article PDF–1.8M

Select item 831323910.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 793877011.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 782639312.

LGI1–ADAM22–MAGUK configures transsynaptic nanoalignment for synaptic transmission and epilepsy prevention

Yuko Fukata, Xiumin Chen, Satomi Chiken, Yoko Hirano, Atsushi Yamagata, Hiroki Inahashi, Makoto Sanbo, Hiromi Sano, Teppei Goto, Masumi Hirabayashi, Hans-Christian Kornau, Harald Prüss, Atsushi Nambu, Shuya Fukai, Roger A. Nicoll, Masaki Fukata

Proc Natl Acad Sci U S A. 2021 Jan 19; 118(3): e2022580118. Published online 2021 Jan 4. doi: 10.1073/pnas.2022580118

PMCID:: PMC7826393

Abstract Article PDF–2.6M

Select item 748440313.

GRK5 Controls SAP97-Dependent Cardiotoxic β₁ Adrenergic Receptor-CaMKII Signaling in Heart Failure

Bing Xu, Minghui Li, Ying Wang, Meimi Zhao, Stefano Morotti, Qian Shi, Qingtong Wang, Federica Barbagallo, Jian-Peng Teoh, Gopireddy R. Reddy, Elizabeth F. Bayne, Yongming Liu, Ao Shen, Jose L. Puglisi, Ying Ge, Ji Li, Eleonora Grandi, Madeline Nieves-Cintron, Yang K. Xiang

Circ Res. Author manuscript; available in PMC 2021 Aug 28.

Published in final edited form as: Circ Res. 2020 Aug 28; 127(6): 796–810. Published online 2020 Jun 8. doi: 10.1161/CIRCRESAHA.119.316319

PMCID:: PMC7484403

Abstract Article PDF–2.7M

Select item 731169514.

Abnormal myocardial expression of SAP97 is associated with arrhythmogenic risk

Hassan Musa, Cherisse A. Marcou, Todd J. Herron, Michael A. Makara, David J. Tester, Ryan P. O’Connell, Brad Rosinski, Guadalupe Guerrero-Serna, Michelle L Milstein, André Monteiro da Rocha, Dan Ye, Lia Crotti, Vladislav V. Nesterenko, Silvia Castelletti, Margherita Torchio, Maria-Christina Kotta, Federica Dagradi, Charles Antzelevitch, Peter J. Mohler, Peter J. Schwartz, Michael J. Ackerman, Justus M. Anumonwo

Am J Physiol Heart Circ Physiol. 2020 Jun 1; 318(6): H1357–H1370. Published online 2020 Mar 20. doi: 10.1152/ajpheart.00481.2019

PMCID:: PMC7311695

Abstract Article

Select item 729503315.

Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant

Meagan A. Quinlan, Matthew J. Robson, Ran Ye, Kristie L. Rose, Kevin L. Schey, Randy D. Blakely

Front Mol Neurosci. 2020; 13: 89. Published online 2020 Jun 8. doi: 10.3389/fnmol.2020.00089

PMCID:: PMC7295033

Abstract Article PDF–2.7M

Select item 685149416.

Joslyn Mills, Toshihiko Hanada, Yoichi Hase, Laura Liscum, Athar H. Chishti

Biochim Biophys Acta Mol Cell Res. Author manuscript; available in PMC 2020 Dec 1.

Published in final edited form as: Biochim Biophys Acta Mol Cell Res. 2019 Dec; 1866(12): 118552. Published online 2019 Sep 2. doi: 10.1016/j.bbamcr.2019.118552

PMCID:: PMC6851494

Abstract Article PDF–2.0M

Select item 682238917.

Dnmt1 is required for proximal-distal patterning of the lung endoderm and for restraining alveolar type 2 cell fate

Derek C. Liberti, Jarod A. Zepp, Christina A. Bartoni, Kyle H. Liberti, Su Zhou, Minmin Lu, Michael P. Morley, Edward E. Morrisey

Dev Biol. Author manuscript; available in PMC 2020 Oct 15.

Published in final edited form as: Dev Biol. 2019 Oct 15; 454(2): 108–117. Published online 2019 Jun 23. doi: 10.1016/j.ydbio.2019.06.019

PMCID:: PMC6822389

Abstract Article PDF–4.9M

Select item 678896218.

Behavioral changes and growth deficits in a CRISPR engineered mouse model of the schizophrenia-associated 3q29 deletion

Timothy P. Rutkowski, Ryan H. Purcell, Rebecca M. Pollak, Stephanie M. Grewenow, Georgette M. Gafford, Tamika Malone, Uswa A. Khan, Jason P. Schroeder, Michael P. Epstein, Gary J. Bassell, Stephen T. Warren, David Weinshenker, Tamara Caspary, Jennifer Gladys Mulle

Mol Psychiatry. 2021; 26(3): 772–783. Published online 2019 Apr 11. doi: 10.1038/s41380-019-0413-5

PMCID:: PMC6788962

Abstract Article PDF–1.8M

Select item 675822919.

Association of the Kinesin Superfamily Motor Protein KIF1Bα with Postsynaptic Density-95 (PSD-95), Synapse-Associated Protein-97, and Synaptic Scaffolding Molecule PSD-95/Discs Large/Zona Occludens-1 Proteins

Hyejung Mok, Hyewon Shin, Seho Kim, Jae-Ran Lee, Jiyoung Yoon, Eunjoon Kim

J Neurosci. 2002 Jul 1; 22(13): 5253–5258. doi: 10.1523/JNEUROSCI.22-13-05253.2002

PMCID:: PMC6758229

Abstract Article PDF–478K

Select item 667481820.

A Novel Family of Adhesion-Like Molecules That Interacts with the NMDA Receptor

Chang-Yu Wang, Kai Chang, Ronald S. Petralia, Ya-Xian Wang, Gail K. Seabold, Robert J. Wenthold

J Neurosci. 2006 Feb 22; 26(8): 2174–2183. doi: 10.1523/JNEUROSCI.3799-05.2006

PMCID:: PMC6674818

Abstract Article PDF–601K

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