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Select item 109453491.

NPC1 is required for postnatal islet β cell differentiation by maintaining mitochondria turnover

Bei Liu, Duanyi Hua, Linyan Shen, Tingting Li, Zheying Tao, Chenyang Fu, Zhongzheng Tang, Jie Yang, Li Zhang, Aifang Nie, Yiran Jiang, Jiqiu Wang, Yang Li, Yanyun Gu, Guang Ning

Theranostics. 2024; 14(5): 2058–2074. Published online 2024 Feb 24. doi: 10.7150/thno.90946

PMCID:: PMC10945349

Abstract Article PDF–9.7M

Select item 107351892.

Autonomous and non-cell autonomous role of cilia in structural birth defects in mice

Richard J. B. Francis, Jovenal T. San Agustin, Heather L. Szabo Rogers, Cheng Cui, Julie A. Jonassen, Thibaut Eguether, John A. Follit, Cecilia W. Lo, Gregory J. Pazour

PLoS Biol. 2023 Dec; 21(12): e3002425. Published online 2023 Dec 11. doi: 10.1371/journal.pbio.3002425

PMCID:: PMC10735189

Abstract Article PDF–9.1M

Select item 106638203.

Prdm12 represses the expression of the visceral neuron determinants Phox2a/b in developing somatosensory ganglia

Simon Vermeiren, Pauline Cabochette, Maya Dannawi, Simon Desiderio, Alba Sabaté San José, Younes Achouri, Sadia Kricha, Maren Sitte, Gabriela Salinas-Riester, Benoit Vanhollebeke, Jean-François Brunet, Eric J. Bellefroid

iScience. 2023 Dec 15; 26(12): 108364. Published online 2023 Oct 31. doi: 10.1016/j.isci.2023.108364

PMCID:: PMC10663820

Abstract Article PDF–5.8M

Select item 106627144.

Context-dependent ciliary regulation of hedgehog pathway repression in tissue morphogenesis

Sun-Hee Hwang, Kevin Andrew White, Bandarigoda Nipunika Somatilaka, Baolin Wang, Saikat Mukhopadhyay

PLoS Genet. 2023 Nov; 19(11): e1011028. Published online 2023 Nov 9. doi: 10.1371/journal.pgen.1011028

PMCID:: PMC10662714

Abstract Article PDF–5.4M

Select item 106377765.

Transcriptional control of motor pool formation and motor circuit connectivity by the LIM-HD protein Isl2

Yunjeong Lee, In Seo Yeo, Namhee Kim, Dong-Keun Lee, Kyung-Tai Kim, Jiyoung Yoon, Jawoon Yi, Young Bin Hong, Byung-Ok Choi, Yoichi Kosodo, Daesoo Kim, Jihwan Park, Mi-Ryoung Song

eLife. 2023; 12: e84596. Published online 2023 Oct 23. doi: 10.7554/eLife.84596

PMCID:: PMC10637776

Abstract Article PDF–25M

Select item 104824296.

Coordination between ECM and cell-cell adhesion regulates the development of islet aggregation, architecture, and functional maturation

Wilma Tixi, Maricela Maldonado, Ya-Ting Chang, Amy Chiu, Wilson Yeung, Nazia Parveen, Michael S Nelson, Ryan Hart, Shihao Wang, Wu Jih Hsu, Patrick Fueger, Janel L Kopp, Mark O Huising, Sangeeta Dhawan, Hung Ping Shih

eLife. 2023; 12: e90006. Published online 2023 Aug 23. doi: 10.7554/eLife.90006

PMCID:: PMC10482429

Abstract Article PDF–26M

Select item 104484747.

The SSBP3 co-regulator is required for glucose homeostasis, pancreatic islet architecture, and beta-cell identity

Eliana Toren, Jessica D. Kepple, Kristen V. Coutinho, Samuel O. Poole, Iztiba M. Deeba, Tanya H. Pierre, Yanping Liu, Maigen M. Bethea, Chad S. Hunter

Mol Metab. 2023 Oct; 76: 101785. Published online 2023 Aug 1. doi: 10.1016/j.molmet.2023.101785

PMCID:: PMC10448474

Abstract Article PDF–4.8M

Select item 103931938.

Major β cell-specific functions of NKX2.2 are mediated via the NK2-specific domain

Vladimir Abarinov, Joshua A. Levine, Angela J. Churchill, Bryce Hopwood, Cailin S. Deiter, Michelle A. Guney, Kristen L. Wells, Jessica M. Schrunk, Yuchun Guo, Jennifer Hammelman, David K. Gifford, Mark A. Magnuson, Hynek Wichterle, Lori Sussel

Genes Dev. 2023 Jun 1; 37(11-12): 490–504. doi: 10.1101/gad.350569.123

PMCID:: PMC10393193

Abstract Article PDF–22M

Select item 103570369.

TMEM132A regulates mouse hindgut morphogenesis and caudal development

Huiqing Zeng, Aimin Liu

Development. 2023 Jul 15; 150(14): dev201630. Published online 2023 Jul 13. doi: 10.1242/dev.201630

PMCID:: PMC10357036

Abstract Article

Select item 1033593710.

Spatiotemporal transcriptomic maps of whole mouse embryos at the onset of organogenesis

Abhishek Sampath Kumar, Luyi Tian, Adriano Bolondi, Amèlia Aragonés Hernández, Robert Stickels, Helene Kretzmer, Evan Murray, Lars Wittler, Maria Walther, Gabriel Barakat, Leah Haut, Yechiel Elkabetz, Evan Z. Macosko, Léo Guignard, Fei Chen, Alexander Meissner

Nat Genet. 2023; 55(7): 1176–1185. Published online 2023 Jul 6. doi: 10.1038/s41588-023-01435-6

PMCID:: PMC10335937

Abstract Article PDF–25M

Select item 1026673611.

Yap controls notochord formation and neural tube patterning by integrating mechanotransduction with FoxA2 and Shh expression

Caiqi Cheng, Qian Cong, Yuchen Liu, Yizhong Hu, Guoyan Liang, Kevin Marc Manquiquis Dioneda, Yingzi Yang

Sci Adv. 2023 Jun; 9(24): eadf6927. Published online 2023 Jun 14. doi: 10.1126/sciadv.adf6927

PMCID:: PMC10266736

Abstract Article PDF–2.4M

Select item 1020371012.

Deficiency of Wdr60 and Wdr34 cause distinct neural tube malformation phenotypes in early embryos

Lu Yan, Hailing Yin, Yiwei Mi, Yu Wu, Yufang Zheng

Front Cell Dev Biol. 2023; 11: 1084245. Published online 2023 May 9. doi: 10.3389/fcell.2023.1084245

PMCID:: PMC10203710

Abstract Article PDF–4.6M

Select item 1013048713.

DNA Methylation–Dependent Restriction of Tyrosine Hydroxylase Contributes to Pancreatic β-Cell Heterogeneity

Nazia Parveen, Jean Kimi Wang, Supriyo Bhattacharya, Janielle Cuala, Mohan Singh Rajkumar, Alexandra E. Butler, Xiwei Wu, Hung-Ping Shih, Senta K. Georgia, Sangeeta Dhawan

Diabetes. 2023 May; 72(5): 575–589. Published online 2023 Jan 6. doi: 10.2337/db22-0506

Correction in:: Diabetes. 2023 Dec; 72(12): 1882.

PMCID:: PMC10130487

Abstract Article PDF–1.8M

Select item 1007300914.

Dual mechanism underlying failure of neural tube closure in the Zic2 mutant mouse

Sarah Escuin, Saba Rose Raza-Knight, Dawn Savery, Carles Gaston-Massuet, Gabriel L. Galea, Nicholas D. E. Greene, Andrew J. Copp

Dis Model Mech. 2023 Mar 1; 16(3): dmm049858. Published online 2023 Mar 14. doi: 10.1242/dmm.049858

PMCID:: PMC10073009

Abstract Article

Select item 1002919515.

TBX3 is dynamically expressed in pancreatic organogenesis and fine-tunes regeneration

Michael Karl Melzer, Silvia Schirge, Johann Gout, Frank Arnold, Dharini Srinivasan, Ingo Burtscher, Chantal Allgöwer, Medhanie Mulaw, Friedemann Zengerling, Cagatay Günes, Heiko Lickert, Vincent M. Christoffels, Stefan Liebau, Martin Wagner, Thomas Seufferlein, Christian Bolenz, Anne M. Moon, Lukas Perkhofer, Alexander Kleger

BMC Biol. 2023; 21: 55. Published online 2023 Mar 20. doi: 10.1186/s12915-023-01553-x

PMCID:: PMC10029195

Abstract Article PDF–4.1M

Select item 999952816.

ISL1 controls pancreatic alpha cell fate and beta cell maturation

Romana Bohuslavova, Valeria Fabriciova, Laura Lebrón-Mora, Jessica Malfatti, Ondrej Smolik, Lukas Valihrach, Sarka Benesova, Daniel Zucha, Zuzana Berkova, Frantisek Saudek, Sylvia M Evans, Gabriela Pavlinkova

Cell Biosci. 2023; 13: 53. Published online 2023 Mar 10. doi: 10.1186/s13578-023-01003-9

PMCID:: PMC9999528

Abstract Article PDF–7.7M

Select item 994279017.

TMEM161B regulates cerebral cortical gyration, Sonic Hedgehog signaling, and ciliary structure in the developing central nervous system

Shyam K. Akula, Jack H. Marciano, Youngshin Lim, David Exposito-Alonso, Norma K. Hylton, Grace H. Hwang, Jennifer E. Neil, Nicole Dominado, Rosie K. Bunton-Stasyshyn, Janet H. T. Song, Maya Talukdar, Aloisia Schmid, Lydia Teboul, Alisa Mo, Taehwan Shin, Benjamin Finander, Samantha G. Beck, Rebecca C. Yeh, Aoi Otani, Xuyu Qian, Ellen M. DeGennaro, Fowzan S. Alkuraya, Sateesh Maddirevula, Gregory D. Cascino, Caterina Giannini, Undiagnosed Diseases Network, Lindsay C. Burrage, Jill A. Rosenfield, Shamika Ketkar, Gary D. Clark, Carlos Bacino, Richard A. Lewis, Rosalind A. Segal, J. Fernando Bazan, Kelly A. Smith, Jeffrey A. Golden, Ginam Cho, Christopher A. Walsh

Proc Natl Acad Sci U S A. 2023 Jan 24; 120(4): e2209964120. Published online 2023 Jan 20. doi: 10.1073/pnas.2209964120

PMCID:: PMC9942790

Abstract Article PDF–13M

Select item 986777418.

Jag1-Notch cis-interaction determines cell fate segregation in pancreatic development

Xiaochan Xu, Philip Allan Seymour, Kim Sneppen, Ala Trusina, Anuska la Rosa Egeskov-Madsen, Mette Christine Jørgensen, Mogens Høgh Jensen, Palle Serup

Nat Commun. 2023; 14: 348. Published online 2023 Jan 21. doi: 10.1038/s41467-023-35963-w

PMCID:: PMC9867774

Abstract Article PDF–4.4M

Select item 981066419.

Single-cell transcriptomic analysis reveals diversity within mammalian spinal motor neurons

Ee Shan Liau, Suoqin Jin, Yen-Chung Chen, Wei-Szu Liu, Maëliss Calon, Stéphane Nedelec, Qing Nie, Jun-An Chen

Nat Commun. 2023; 14: 46. Published online 2023 Jan 3. doi: 10.1038/s41467-022-35574-x

PMCID:: PMC9810664

Abstract Article PDF–11M

Select item 980121920.

Inhibition of stearoyl-CoA desaturase 1 in the mouse impairs pancreatic islet morphogenesis and promotes loss of β-cell identity and α-cell expansion in the mature pancreas

Aneta M. Dobosz, Justyna Janikiewicz, Ewelina Krogulec, Anna Dziewulska, Anna Ajduk, Marcin Szpila, Hanna Nieznańska, Andrzej A. Szczepankiewicz, Dorota Wypych, Agnieszka Dobrzyn

Mol Metab. 2023 Jan; 67: 101659. Published online 2022 Dec 15. doi: 10.1016/j.molmet.2022.101659

PMCID:: PMC9801219

Abstract Article PDF–3.9M

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