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Select item 79387701.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 75264592.

Loss of MAGEL2 in Prader-Willi syndrome leads to decreased secretory granule and neuropeptide production

Helen Chen, A. Kaitlyn Victor, Jonathon Klein, Klementina Fon Tacer, Derek J.C. Tai, Celine de Esch, Alexander Nuttle, Jamshid Temirov, Lisa C. Burnett, Michael Rosenbaum, Yiying Zhang, Li Ding, James J. Moresco, Jolene K. Diedrich, John R. Yates, III, Heather S. Tillman, Rudolph L. Leibel, Michael E. Talkowski, Daniel D. Billadeau, Lawrence T. Reiter, Patrick Ryan Potts

JCI Insight. 2020 Sep 3; 5(17): e138576. Published online 2020 Sep 3. doi: 10.1172/jci.insight.138576

PMCID:: PMC7526459

Abstract Article PDF–12M

Select item 73153773.

Inactivation of Rho GTPases by Burkholderia cenocepacia Induces a WASH-Mediated Actin Polymerization that Delays Phagosome Maturation

Glenn F.W. Walpole, Jonathan D. Plumb, Daniel Chung, Brandon Tang, Benoit Boulay, Douglas G. Osborne, Joshua T. Piotrowski, Sergio D. Catz, Daniel D. Billadeau, Sergio Grinstein, Valentin Jaumouillé

Cell Rep. Author manuscript; available in PMC 2020 Jun 25.

Published in final edited form as: Cell Rep. 2020 Jun 2; 31(9): 107721. doi: 10.1016/j.celrep.2020.107721

PMCID:: PMC7315377

Abstract Article PDF–2.0M

Select item 66927704.

Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics

Joel D. Federspiel, Todd M. Greco, Krystal K. Lum, Ileana M. Cristea

Mol Cell Proteomics. 2019 Aug 9; 18(8 Suppl 1): S92–S113. Published online 2019 Apr 30. doi: 10.1074/mcp.RA118.001253

PMCID:: PMC6692770

Abstract Article PDF–7.7M

Select item 66291195.

The hepatic WASH complex is required for efficient plasma LDL and HDL cholesterol clearance

Melinde Wijers, Paolo Zanoni, Nalan Liv, Dyonne Y. Vos, Michelle Y. Jäckstein, Marieke Smit, Sanne Wilbrink, Justina C. Wolters, Ydwine T. van der Veen, Nicolette Huijkman, Daphne Dekker, Niels Kloosterhuis, Theo H. van Dijk, Daniel D. Billadeau, Folkert Kuipers, Judith Klumperman, Arnold von Eckardstein, Jan Albert Kuivenhoven, Bart van de Sluis

JCI Insight. 2019 Jun 6; 4(11): e126462. Published online 2019 Jun 6. doi: 10.1172/jci.insight.126462

PMCID:: PMC6629119

Abstract Article PDF–10M

Select item 61211976.

Parkin mediates the ubiquitination of VPS35 and modulates retromer-dependent endosomal sorting

Erin T Williams, Liliane Glauser, Elpida Tsika, Haisong Jiang, Shariful Islam, Darren J Moore

Hum Mol Genet. 2018 Sep 15; 27(18): 3189–3205. Published online 2018 Jun 11. doi: 10.1093/hmg/ddy224

PMCID:: PMC6121197

Abstract Article PDF–2.4M

Select item 54672427.

WASH maintains NKp46⁺ ILC3 cells by promoting AHR expression

Pengyan Xia, Jing Liu, Shuo Wang, Buqing Ye, Ying Du, Zhen Xiong, Ze-Guang Han, Liang Tong, Zusen Fan

Nat Commun. 2017; 8: 15685. Published online 2017 Jun 7. doi: 10.1038/ncomms15685

PMCID:: PMC5467242

Abstract Article PDF–1.8M

Select item 51482288.

The Proteome of BLOC-1 Genetic Defects Identifies the Arp2/3 Actin Polymerization Complex to Function Downstream of the Schizophrenia Susceptibility Factor Dysbindin at the Synapse

Avanti Gokhale, Cortnie Hartwig, Amanda H. Freeman, Ravi Das, Stephanie A. Zlatic, Rachel Vistein, Amelia Burch, Guillemette Carrot, Arielle F. Lewis, Sheldon Nelms, Dion K. Dickman, Manojkumar A. Puthenveedu, Daniel N. Cox, Victor Faundez

J Neurosci. 2016 Dec 7; 36(49): 12393–12411. doi: 10.1523/JNEUROSCI.1321-16.2016

PMCID:: PMC5148228

Abstract Article PDF–5.7M

Select item 50825499.

Loss of strumpellin in the melanocytic lineage impairs the WASH Complex but does not affect coat colour

Benjamin J. Tyrrell, Emma F. Woodham, Heather J. Spence, Douglas Strathdee, Robert H. Insall, Laura M. Machesky

Pigment Cell Melanoma Res. 2016 Sep; 29(5): 559–571. Published online 2016 Sep 12. doi: 10.1111/pcmr.12506

PMCID:: PMC5082549

Abstract Article PDF–2.6M

Select item 479296310.

CCC- and WASH-mediated endosomal sorting of LDLR is required for normal clearance of circulating LDL

Paulina Bartuzi, Daniel D. Billadeau, Robert Favier, Shunxing Rong, Daphne Dekker, Alina Fedoseienko, Hille Fieten, Melinde Wijers, Johannes H. Levels, Nicolette Huijkman, Niels Kloosterhuis, Henk van der Molen, Gemma Brufau, Albert K. Groen, Alison M. Elliott, Jan Albert Kuivenhoven, Barbara Plecko, Gernot Grangl, Julie McGaughran, Jay D. Horton, Ezra Burstein, Marten H. Hofker, Bart van de Sluis

Nat Commun. 2016; 7: 10961. Published online 2016 Mar 11. doi: 10.1038/ncomms10961

PMCID:: PMC4792963

Abstract Article PDF–2.4M

Select item 417222011.

WASH is required for the differentiation commitment of hematopoietic stem cells in a c-Myc–dependent manner

Pengyan Xia, Shuo Wang, Guanling Huang, Pingping Zhu, Man Li, Buqing Ye, Ying Du, Zusen Fan

J Exp Med. 2014 Sep 22; 211(10): 2119–2134. doi: 10.1084/jem.20140169

PMCID:: PMC4172220

Abstract Article PDF–3.6M

Select item 412329712.

RNF2 is recruited by WASH to ubiquitinate AMBRA1 leading to downregulation of autophagy

Pengyan Xia, Shuo Wang, Guanling Huang, Ying Du, Pingping Zhu, Man Li, Zusen Fan

Cell Res. 2014 Aug; 24(8): 943–958. Published online 2014 Jul 1. doi: 10.1038/cr.2014.85

PMCID:: PMC4123297

Abstract Article PDF–2.6M

Select item 408326013.

WASH complex regulates Arp2/3 complex for actin-based polar body extrusion in mouse oocytes

Fei Wang, Liang Zhang, Guang-Li Zhang, Zhen-Bo Wang, Xiang-Shun Cui, Nam-Hyung Kim, Shao-Chen Sun

Sci Rep. 2014; 4: 5596. Published online 2014 Jul 7. doi: 10.1038/srep05596

PMCID:: PMC4083260

Abstract Article PDF–1.3M

Select item 404176314.

Dendritic Cells Utilize the Evolutionarily Conserved WASH and Retromer Complexes to Promote MHCII Recycling and Helper T Cell Priming

Daniel B. Graham, Douglas G. Osborne, Joshua T. Piotrowski, Timothy S. Gomez, Grzegorz B. Gmyrek, Holly M. Akilesh, Adish Dani, Daniel D. Billadeau, Wojciech Swat

PLoS One. 2014; 9(6): e98606. Published online 2014 Jun 2. doi: 10.1371/journal.pone.0098606

PMCID:: PMC4041763

Abstract Article PDF–2.4M

Select item 387143615.

Endosomal WASH and exocyst complexes control exocytosis of MT1-MMP at invadopodia

Pedro Monteiro, Carine Rossé, Antonio Castro-Castro, Marie Irondelle, Emilie Lagoutte, Perrine Paul-Gilloteaux, Claire Desnos, Etienne Formstecher, François Darchen, David Perrais, Alexis Gautreau, Maud Hertzog, Philippe Chavrier

J Cell Biol. 2013 Dec 23; 203(6): 1063–1079. doi: 10.1083/jcb.201306162

PMCID:: PMC3871436

Abstract Article PDF–4.7M

Select item 380143416.

WASH inhibits autophagy through suppression of Beclin 1 ubiquitination

Pengyan Xia, Shuo Wang, Ying Du, Zhenao Zhao, Lei Shi, Lei Sun, Guanling Huang, Buqing Ye, Chong Li, Zhonghua Dai, Ning Hou, Xuan Cheng, Qingyuan Sun, Lei Li, Xiao Yang, Zusen Fan

EMBO J. 2013 Oct 16; 32(20): 2685–2696. Published online 2013 Aug 23. doi: 10.1038/emboj.2013.189

PMCID:: PMC3801434

Abstract Article PDF–2.4M

Select item 364027617.

Regulation of WASH-Dependent Actin Polymerization and Protein Trafficking by Ubiquitination

Yi-Heng Hao, Jennifer M. Doyle, Saumya Ramanathan, Timothy S. Gomez, Da Jia, Ming Xu, Zhijian J. Chen, Daniel D. Billadeau, Michael K. Rosen, Patrick Ryan Potts

Cell. Author manuscript; available in PMC 2013 Aug 28.

Published in final edited form as: Cell. 2013 Feb 28; 152(5): 1051–1064. doi: 10.1016/j.cell.2013.01.051

PMCID:: PMC3640276

Abstract Article PDF–6.0M

Select item 362308718.

WASH Knockout T Cells Demonstrate Defective Receptor Trafficking, Proliferation, and Effector Function

Joshua T. Piotrowski, Timothy S. Gomez, Renee A. Schoon, Ashutosh K. Mangalam, Daniel D. Billadeau

Mol Cell Biol. 2013 Mar; 33(5): 958–973. doi: 10.1128/MCB.01288-12

PMCID:: PMC3623087

Abstract Article PDF–3.0M

Select item 341831519.

Trafficking defects in WASH-knockout fibroblasts originate from collapsed endosomal and lysosomal networks

Timothy S. Gomez, Jacquelyn A. Gorman, Amaia Artal-Martinez de Narvajas, Alexander O. Koenig, Daniel D. Billadeau

Mol Biol Cell. 2012 Aug 15; 23(16): 3215–3228. doi: 10.1091/mbc.E12-02-0101

PMCID:: PMC3418315

Abstract Article PDF–7.6M

Select item 317805920.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

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