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Items: 1 to 20 of 80

1.
Fatty Acids Inhibit LAMP2-Mediated Autophagy Flux via Activating ER Stress Pathway in Alcohol-Related Liver Disease
Wei Guo, Wei Zhong, Liuyi Hao, Haibo Dong, Xinguo Sun, Ruichao Yue, Tianjiao Li, Zhanxiang Zhou
Cell Mol Gastroenterol Hepatol. 2021; 12(5): 1599–1615. Published online 2021 Jul 17. doi: 10.1016/j.jcmgh.2021.07.002
PMCID:
PMC8536789
AbstractArticlePDF–6.3M
2.
Hypoxia-inducible lipid droplet-associated induces DGAT1 and promotes lipid storage in hepatocytes
Montserrat A. de la Rosa Rodriguez, Lei Deng, Anne Gemmink, Michel van Weeghel, Marie Louise Aoun, Christina Warnecke, Rajat Singh, Jan Willem Borst, Sander Kersten
Mol Metab. 2021 May; 47: 101168. Published online 2021 Jan 16. doi: 10.1016/j.molmet.2021.101168
PMCID:
PMC7881268
AbstractArticlePDF–4.4M
3.
Hepatic synthesis of triacylglycerols containing medium-chain fatty acids is dominated by diacylglycerol acyltransferase 1 and efficiently inhibited by etomoxir
Klaus Wunderling, Christina Leopold, Isabell Jamitzky, Mohamed Yaghmour, Fabian Zink, Dagmar Kratky, Christoph Thiele
Mol Metab. 2021 Mar; 45: 101150. Published online 2020 Dec 23. doi: 10.1016/j.molmet.2020.101150
PMCID:
PMC7843514
AbstractArticlePDF–3.1M
4.
Lipid Droplets in Brown Adipose Tissue Are Dispensable for Cold-Induced Thermogenesis
Chandramohan Chitraju, Alexander W. Fischer, Robert V. Farese, Jr., Tobias C. Walther
Cell Rep. Author manuscript; available in PMC 2020 Nov 28.
Published in final edited form as: Cell Rep. 2020 Nov 3; 33(5): 108348. doi: 10.1016/j.celrep.2020.108348
PMCID:
PMC7696656
AbstractArticlePDF–1.6M
5.
BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)
Kou Motani, Hidetaka Kosako
J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323
PMCID:
PMC7415991
AbstractArticlePDF–2.0M
6.
Intestine-specific DGAT1 deficiency improves atherosclerosis in apolipoprotein E knockout mice by reducing systemic cholesterol burden
Nemanja Vujić, Melanie Korbelius, Vinay Sachdev, Silvia Rainer, Andreas Zimmer, Anton Huber, Branislav Radović, Dagmar Kratky
Atherosclerosis. Author manuscript; available in PMC 2020 Oct 27.
Published in final edited form as: Atherosclerosis. 2020 Oct 1; 310: 26–36. Published online 2020 Aug 10. doi: 10.1016/j.atherosclerosis.2020.07.030
PMCID:
PMC7116265
AbstractArticlePDF–1.6M
7.
Glycogen Dynamics Drives Lipid Droplet Biogenesis during Brown Adipocyte Differentiation
Alicia Mayeuf-Louchart, Steve Lancel, Yasmine Sebti, Benoit Pourcet, Anne Loyens, Stéphane Delhaye, Christian Duhem, Justine Beauchamp, Lise Ferri, Quentin Thorel, Alexis Boulinguiez, Mathilde Zecchin, Julie Dubois-Chevalier, Jérôme Eeckhoute, Logan T. Vaughn, Peter J. Roach, Christian Dani, Bartholomew A. Pederson, Stéphane D. Vincent, Bart Staels, Hélène Duez
Cell Rep. 2019 Nov 5; 29(6): 1410–1418.e6. Published online 2019 Nov 5. doi: 10.1016/j.celrep.2019.09.073
PMCID:
PMC7057258
AbstractArticle
8.
DGAT1 DEFICIENCY DISRUPTS LYSOSOME FUNCTION IN ENTEROCYTES DURING DIETARY FAT ABSORPTION
Yu-Han Hung, Kimberly K. Buhman
Biochim Biophys Acta Mol Cell Biol Lipids. Author manuscript; available in PMC 2020 Apr 1.
Published in final edited form as: Biochim Biophys Acta Mol Cell Biol Lipids. 2019 Apr; 1864(4): 587–595. Published online 2018 Oct 17. doi: 10.1016/j.bbalip.2018.10.007
PMCID:
PMC7024568
AbstractArticlePDF–1.8M
9.
WDFY4 is required for cross-presentation in response to viral and tumor antigens
Derek J. Theisen, Jesse T. Davidson, IV, Carlos G. Briseño, Marco Gargaro, Elvin J. Lauron, Qiuling Wang, Pritesh Desai, Vivek Durai, Prachi Bagadia, Joshua R. Brickner, Wandy L. Beatty, Herbert W. Virgin, William E. Gillanders, Nima Mosammaparast, Michael S. Diamond, L. David Sibley, Wayne Yokoyama, Robert D. Schreiber, Theresa L. Murphy, Kenneth M. Murphy
Science. Author manuscript; available in PMC 2019 Jul 24.
Published in final edited form as: Science. 2018 Nov 9; 362(6415): 694–699. doi: 10.1126/science.aat5030
PMCID:
PMC6655551
AbstractArticlePDF–1020K
10.
DGAT1 inhibits retinol-dependent regulatory T cell formation and mediates autoimmune encephalomyelitis
Kareem L. Graham, Bonnie J. Werner, Kimberly M. Moyer, Alycia K. Patton, Charles R. Krois, Hong Sik Yoo, Maria Tverskoy, Melissa LaJevic, Joseph L. Napoli, Raymond A. Sobel, Brian A. Zabel, Eugene C. Butcher
Proc Natl Acad Sci U S A. 2019 Feb 19; 116(8): 3126–3135. Published online 2019 Feb 4. doi: 10.1073/pnas.1817669116
PMCID:
PMC6386656
AbstractArticlePDF–1.4M
11.
Hepatic VLDL secretion: DGAT1 determines particle size but not particle number, which can be supported entirely by DGAT2
Zehra Irshad, Nikola Chmel, Raghu Adya, Victor A. Zammit
J Lipid Res. 2019 Jan; 60(1): 111–120. Published online 2018 Nov 5. doi: 10.1194/jlr.M089300
PMCID:
PMC6314258
AbstractArticlePDF–952K
12.
Triglyceride Synthesis by DGAT1 Protects Adipocytes from Lipid-Induced ER Stress during Lipolysis
Chandramohan Chitraju, Niklas Mejhert, Joel T. Haas, L. Grisell Diaz-Ramirez, Carrie A. Grueter, Jason E. Imbriglio, Shirly Pinto, Suneil K. Koliwad, Tobias C. Walther, Robert V. Farese, Jr
Cell Metab. Author manuscript; available in PMC 2018 Oct 19.
Published in final edited form as: Cell Metab. 2017 Aug 1; 26(2): 407–418.e3. doi: 10.1016/j.cmet.2017.07.012
PMCID:
PMC6195226
AbstractArticlePDF–2.7M
13.
The Role of Diacylglycerol Acyltransferase (DGAT) 1 and 2 in Cardiac Metabolism and Function
Nathan D. Roe, Michal K. Handzlik, Tao Li, Rong Tian
Sci Rep. 2018; 8: 4983. Published online 2018 Mar 21. doi: 10.1038/s41598-018-23223-7
PMCID:
PMC5862879
AbstractArticlePDF–2.0M
14.
DGAT1-dependent lipid droplet biogenesis protects mitochondrial function during starvation-induced autophagy
Truc B. Nguyen, Sharon M. Louie, Joseph R. Daniele, Quan Tran, Andrew Dillin, Roberto Zoncu, Daniel K. Nomura, James A. Olzmann
Dev Cell. Author manuscript; available in PMC 2018 Jul 10.
Published in final edited form as: Dev Cell. 2017 Jul 10; 42(1): 9–21.e5. doi: 10.1016/j.devcel.2017.06.003
PMCID:
PMC5553613
AbstractArticlePDF–2.2M
15.
Dgat1 and Dgat2 regulate enterocyte triacylglycerol distribution and alter proteins associated with cytoplasmic lipid droplets in response to dietary fat
Yu-Han Hung, Alicia L. Carreiro, Kimberly K. Buhman
Biochim Biophys Acta. Author manuscript; available in PMC 2018 Jun 1.
Published in final edited form as: Biochim Biophys Acta. 2017 Jun; 1862(6): 600–614. Published online 2017 Feb 27. doi: 10.1016/j.bbalip.2017.02.014
PMCID:
PMC5503214
AbstractArticlePDF–2.0M
16.
Synthesis of neutral ether lipid monoalkyl-diacylglycerol by lipid acyltransferases
Zhengping Ma, Joelle M. Onorato, Luping Chen, David W. Nelson, Chi-Liang Eric Yen, Dong Cheng
J Lipid Res. 2017 Jun; 58(6): 1091–1099. Published online 2017 Apr 18. doi: 10.1194/jlr.M073445
PMCID:
PMC5454505
AbstractArticlePDF–1.2M
17.
Analysis of Differentially Expressed Genes in Gastrocnemius Muscle between DGAT1 Transgenic Mice and Wild-Type Mice
Fei Ying, Hao Gu, Yuanzhu Xiong, Bo Zuo
Biomed Res Int. 2017; 2017: 5404682. Published online 2017 Mar 13. doi: 10.1155/2017/5404682
PMCID:
PMC5366756
AbstractArticlePDF–957K
18.
Saturated fatty acids engage an IRE1α-dependent pathway to activate the NLRP3 inflammasome in myeloid cells
Megan M. Robblee, Charles C. Kim, Jess Porter Abate, Martin Valdearcos, Karin L.M. Sandlund, Meera Shenoy, Romain Volmer, Takao Iwawaki, Suneil K. Koliwad
Cell Rep. Author manuscript; available in PMC 2017 Jan 18.
Published in final edited form as: Cell Rep. 2016 Mar 22; 14(11): 2611–2623. Published online 2016 Mar 10. doi: 10.1016/j.celrep.2016.02.053
PMCID:
PMC5242525
AbstractArticlePDF–1.1M
19.
Diacylglycerol acyltransferase 2 links glucose utilization to fatty acid oxidation in the brown adipocytes
Zehra Irshad, Federica Dimitri, Mark Christian, Victor A. Zammit
J Lipid Res. 2017 Jan; 58(1): 15–30. Published online 2016 Dec 29. doi: 10.1194/jlr.M068197
PMCID:
PMC5234708
AbstractArticlePDF–1.6M
20.
Hepatic Glucocorticoid Receptor Plays a Greater Role Than Adipose GR in Metabolic Syndrome Despite Renal Compensation
Sandip K. Bose, Irina Hutson, Charles A. Harris
Endocrinology. 2016 Dec; 157(12): 4943–4960. Published online 2016 Oct 18. doi: 10.1210/en.2016-1615
PMCID:
PMC5133352
AbstractArticle

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