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Items: 1 to 20 of 42

1.
Disruption of proteostasis causes IRE1 mediated reprogramming of alveolar epithelial cells
Jeremy Katzen, Luis Rodriguez, Yaniv Tomer, Apoorva Babu, Ming Zhao, Aditi Murthy, Paige Carson, Matthew Barrett, Maria C. Basil, Justine Carl, John P. Leach, Michael Morley, Matthew D. McGraw, Surafel Mulugeta, Timothy Pelura, Glenn Rosen, Edward E. Morrisey, Michael F. Beers
Proc Natl Acad Sci U S A. 2022 Oct 25; 119(43): e2123187119. Published online 2022 Oct 17. doi: 10.1073/pnas.2123187119
PMCID:
PMC9618079
AbstractArticlePDF–3.2M
2.
O-fucosylation of thrombospondin type 1 repeats is essential for ECM remodeling and signaling during bone development
Sanjiv Neupane, Steven J. Berardinelli, Daniel C. Cameron, Richard C. Grady, David E. Komatsu, Christopher J. Percival, Megumi Takeuchi, Atsuko Ito, Ta-Wei Liu, Alison V. Nairn, Kelley W. Moremen, Robert S. Haltiwanger, Bernadette C. Holdener
Matrix Biol. Author manuscript; available in PMC 2022 Oct 27.
Published in final edited form as: Matrix Biol. 2022 Mar; 107: 77–96. Published online 2022 Feb 12. doi: 10.1016/j.matbio.2022.02.002
PMCID:
PMC9606722
AbstractArticlePDF–6.7M
3.
The epithelial-specific ER stress sensor ERN2/IRE1β enables host-microbiota crosstalk to affect colon goblet cell development
Michael J. Grey, Heidi De Luca, Doyle V. Ward, Irini A.M. Kreulen, Katlynn Bugda Gwilt, Sage E. Foley, Jay R. Thiagarajah, Beth A. McCormick, Jerrold R. Turner, Wayne I. Lencer
J Clin Invest. 2022 Sep 1; 132(17): e153519. Published online 2022 Sep 1. doi: 10.1172/JCI153519
PMCID:
PMC9435652
AbstractArticlePDF–8.6M
4.
Pharmacologic IRE1/XBP1s activation promotes systemic adaptive remodeling in obesity
Aparajita Madhavan, Bernard P. Kok, Bibiana Rius, Julia M. D. Grandjean, Adekunle Alabi, Verena Albert, Ara Sukiasyan, Evan T. Powers, Andrea Galmozzi, Enrique Saez, R. Luke Wiseman
Nat Commun. 2022; 13: 608. Published online 2022 Feb 1. doi: 10.1038/s41467-022-28271-2
PMCID:
PMC8807832
AbstractArticlePDF–1.3M
5.
Mouse Hepatitis Virus Infection Activates the IRE1/XBP1 Pathway of the Unfolded Protein Response
John Bechill, Zhongbin Chen, Joseph W. Brewer, Susan C. Baker
The Nidoviruses. 2006; 581: 139–144. doi: 10.1007/978-0-387-33012-9_24
PMCID:
PMC7123145
ArticlePDF–997K
6.
IRE1-XBP1 Pathway of the Unfolded Protein Response Is Required during Early Differentiation of C2C12 Myoblasts
Yukako Tokutake, Keita Yamada, Satoko Hayashi, Wataru Arai, Takafumi Watanabe, Shinichi Yonekura
Int J Mol Sci. 2020 Jan; 21(1): 182. Published online 2019 Dec 26. doi: 10.3390/ijms21010182
PMCID:
PMC6981822
AbstractArticlePDF–2.5M
7.
Modulation of the Sigma-1 Receptor-IRE1 pathway is beneficial in preclinical models of inflammation and sepsis.
Dorian A Rosen, Scott M. Seki, Anthony Fernández-Castañeda, Rebecca M. Beiter, Jacob D. Eccles, Judith A. Woodfolk, Alban Gaultier
Sci Transl Med. Author manuscript; available in PMC 2019 Dec 30.
Published in final edited form as: Sci Transl Med. 2019 Feb 6; 11(478): eaau5266. doi: 10.1126/scitranslmed.aau5266
Correction in:
Sci Transl Med. 2019 Mar 27; 11(485)
PMCID:
PMC6936250
AbstractArticlePDF–983K
8.
Reactive oxygen species‐mediated endoplasmic reticulum stress response induces apoptosis of Mycobacterium avium‐infected macrophages by activating regulated IRE1‐dependent decay pathway
Dam Go, Junghwan Lee, Ji‐Ae Choi, Soo‐Na Cho, Seon‐Hwa Kim, Sang‐Hun Son, Chang‐Hwa Song
Cell Microbiol. 2019 Dec; 21(12): e13094. Published online 2019 Aug 16. doi: 10.1111/cmi.13094
PMCID:
PMC6899680
AbstractArticlePDF–1.7M
9.
XBP1S Regulates MUC5B in a Promoter Variant–Dependent Pathway in Idiopathic Pulmonary Fibrosis Airway Epithelia
Gang Chen, Carla M. P. Ribeiro, Ling Sun, Kenichi Okuda, Takafumi Kato, Rodney C. Gilmore, Mary B. Martino, Hong Dang, Aiman Abzhanova, Jennifer M. Lin, Emily A. Hull-Ryde, Allison S. Volmer, Scott H. Randell, Alessandra Livraghi-Butrico, Yingfeng Deng, Philipp E. Scherer, Barry R. Stripp, Wanda K. O’Neal, Richard C. Boucher
Am J Respir Crit Care Med. 2019 Jul 15; 200(2): 220–234. Published online 2019 Jul 15. doi: 10.1164/rccm.201810-1972OC
Correction in:
Am J Respir Crit Care Med. 2019 Oct 15; 200(8): 1074.
PMCID:
PMC6635783
AbstractArticlePDF–2.6M
10.
Degradation of Blos1 mRNA by IRE1 repositions lysosomes and protects cells from stress
Donghwi Bae, Kristin A. Moore, Jessica M. Mella, Samantha Y. Hayashi, Julie Hollien
J Cell Biol. 2019 Apr 1; 218(4): 1118–1127. Published online 2019 Feb 20. doi: 10.1083/jcb.201809027
PMCID:
PMC6446841
AbstractArticlePDF–2.4M
11.
Phosphorylation of IRE1 at S729 regulates RIDD in B cells and antibody production after immunization
Chih-Hang Anthony Tang, Shiun Chang, Adrienne W. Paton, James C. Paton, Dmitry I. Gabrilovich, Hidde L. Ploegh, Juan R. Del Valle, Chih-Chi Andrew Hu
J Cell Biol. 2018 May 7; 217(5): 1739–1755. doi: 10.1083/jcb.201709137
PMCID:
PMC5940306
AbstractArticlePDF–3.2M
12.
Regulated Inositol-Requiring Enzyme 1 dependent mRNA decay sets the threshold for dendritic cell survival
Simon J. Tavernier, Fabiola Osorio, Lana Vandersarren, Jessica Vetters, Nele Vanlangenakker, Gert Van Isterdael, Karl Vergote, Eef Parthoens, Lianne van de Laar, Takao Iwawaki, Juan R. Del Valle, Andrew Hu, Bart N. Lambrecht, Sophie Janssens
Nat Cell Biol. Author manuscript; available in PMC 2017 Dec 1.
Published in final edited form as: Nat Cell Biol. 2017 Jun; 19(6): 698–710. Published online 2017 May 1. doi: 10.1038/ncb3518
PMCID:
PMC5563826
AbstractArticlePDF–1.5M
13.
Endotoxemia-mediated activation of acetyltransferase P300 impairs insulin signaling in obesity
Jia Cao, Jinghua Peng, Hongying An, Qiyi He, Tatiana Boronina, Shaodong Guo, Morris F. White, Philip A. Cole, Ling He
Nat Commun. 2017; 8: 131. Published online 2017 Jul 25. doi: 10.1038/s41467-017-00163-w
PMCID:
PMC5526866
AbstractArticlePDF–2.9M
14.
Defective ATG16L1-mediated removal of IRE1α drives Crohn’s disease–like ileitis
Markus Tschurtschenthaler, Timon E. Adolph, Jonathan W. Ashcroft, Lukas Niederreiter, Richa Bharti, Svetlana Saveljeva, Joya Bhattacharyya, Magdalena B. Flak, David Q. Shih, Gwenny M. Fuhler, Miles Parkes, Kenji Kohno, Takao Iwawaki, C. Janneke van der Woude, Heather P. Harding, Andrew M. Smith, Maikel P. Peppelenbosch, Stephan R. Targan, David Ron, Philip Rosenstiel, Richard S. Blumberg, Arthur Kaser
J Exp Med. 2017 Feb; 214(2): 401–422. doi: 10.1084/jem.20160791
PMCID:
PMC5294857
AbstractArticlePDF–4.3M
15.
PERK regulated miR-424(322)-503 cluster fine-tunes activation of IRE1 and ATF6 during Unfolded Protein Response
Ananya Gupta, Muhammad Mosaraf Hossain, Danielle E. Read, Claudio Hetz, Afshin Samali, Sanjeev Gupta
Sci Rep. 2015; 5: 18304. Published online 2015 Dec 17. doi: 10.1038/srep18304
PMCID:
PMC4682135
AbstractArticlePDF–2.1M
16.
IRE1 prevents endoplasmic reticulum membrane permeabilization and cell death under pathological conditions
Kohsuke Kanekura, Xiucui Ma, John T. Murphy, Lihua J. Zhu, Abhinav Diwan, Fumihiko Urano
Sci Signal. Author manuscript; available in PMC 2015 Jul 6.
Published in final edited form as: Sci Signal. 2015; 8(382): ra62. Published online 2015 Jun 23. doi: 10.1126/scisignal.aaa0341
PMCID:
PMC4492519
AbstractArticlePDF–2.1M
17.
IRE1 Phosphatase PP2Ce Regulates Adaptive ER Stress Response in the Postpartum Mammary Gland
Shuxun Ren, Gang Lu, Asuka Ota, Z. Hong Zhou, Thomas M. Vondriska, Timothy F. Lane, Yibin Wang
PLoS One. 2014; 9(11): e111606. Published online 2014 Nov 4. doi: 10.1371/journal.pone.0111606
PMCID:
PMC4219728
AbstractArticlePDF–1.3M
18.
Lack of XBP-1 Impedes Murine Cytomegalovirus Gene Expression
Adi Drori, Martin Messerle, Wolfram Brune, Boaz Tirosh
PLoS One. 2014; 9(10): e110942. Published online 2014 Oct 21. doi: 10.1371/journal.pone.0110942
PMCID:
PMC4205010
AbstractArticlePDF–2.9M
19.
The ER stress transducer IRE1β is required for airway epithelial mucin production
MB Martino, L Jones, B Brighton, C Ehre, L Abdulah, CW Davis, D Ron, WK O’Neal, CMP Ribeiro
Mucosal Immunol. Author manuscript; available in PMC 2014 May 23.
Published in final edited form as: Mucosal Immunol. 2013 May; 6(3): 639–654. Published online 2012 Nov 21. doi: 10.1038/mi.2012.105
PMCID:
PMC4031691
AbstractArticlePDF–6.0M
20.
Toll-like receptor-mediated IRE1α activation as a therapeutic target for inflammatory arthritis
Quan Qiu, Ze Zheng, Lin Chang, Yuan-Si Zhao, Can Tan, Aditya Dandekar, Zheng Zhang, Zhenghong Lin, Ming Gui, Xiu Li, Tongshuai Zhang, Qingfei Kong, Hulun Li, Sha Chen, An Chen, Randal J Kaufman, Wei-Lei Yang, Hui-Kuan Lin, Donna Zhang, Harris Perlman, Edward Thorp, Kezhong Zhang, Deyu Fang
EMBO J. 2013 Sep 11; 32(18): 2477–2490. Published online 2013 Aug 13. doi: 10.1038/emboj.2013.183
PMCID:
PMC3770952
AbstractArticlePDF–1.8M

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