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Select item 108242741.

Impaired hemostatic activity of healthy transfused platelets in inherited and acquired platelet disorders: mechanisms and implications

Robert H. Lee, Raymond Piatt, Ankita Dhenge, María L. Lozano, Verónica Palma-Barqueros, José Rivera, Wolfgang Bergmeier

Sci Transl Med. Author manuscript; available in PMC 2024 Jan 29.

Published in final edited form as: Sci Transl Med. 2019 Dec 11; 11(522): eaay0203. doi: 10.1126/scitranslmed.aay0203

PMCID:: PMC10824274

Abstract Article PDF–1.6M

Select item 84860002.

CalDAG-GEFI mediates striatal cholinergic modulation of dendritic excitability, synaptic plasticity and psychomotor behaviors

Jill R. Crittenden, Shenyu Zhai, Magdalena Sauvage, Takashi Kitsukawa, Eric Burguière, Morgane Thomsen, Hui Zhang, Cinzia Costa, Giuseppina Martella, Veronica Ghiglieri, Barbara Picconi, Karen A. Pescatore, Ellen M. Unterwald, Walker S. Jackson, David E. Housman, S. Barak Caine, David Sulzer, Paolo Calabresi, Anne C. Smith, D. James Surmeier, Ann M. Graybiel

Neurobiol Dis. Author manuscript; available in PMC 2021 Oct 1.

Published in final edited form as: Neurobiol Dis. 2021 Oct; 158: 105473. Published online 2021 Aug 8. doi: 10.1016/j.nbd.2021.105473

PMCID:: PMC8486000

Abstract Article PDF–1.2M

Select item 71322563.

Parcellation of the striatal complex into dorsal and ventral districts

Shih-Yun Chen, Kuan-Ming Lu, Hsin-An Ko, Ting-Hao Huang, Janice Hsin-Jou Hao, Yu-Ting Yan, Sunny Li-Yun Chang, Sylvia M. Evans, Fu-Chin Liu

Proc Natl Acad Sci U S A. 2020 Mar 31; 117(13): 7418–7429. Published online 2020 Mar 13. doi: 10.1073/pnas.1921007117

PMCID:: PMC7132256

Abstract Article PDF–4.5M

Select item 60208164.

Protein kinase C signaling dysfunction in von Willebrand disease (p.V1316M) type 2B platelets

Caterina Casari, David S. Paul, Sophie Susen, Cécile Lavenu-Bombled, Annie Harroche, Raymond Piatt, Kathryn O. Poe, Robert H. Lee, Marijke Bryckaert, Olivier D. Christophe, Peter J. Lenting, Cécile V. Denis, Wolfgang Bergmeier

Blood Adv. 2018 Jun 26; 2(12): 1417–1428. Published online 2018 Jun 20. doi: 10.1182/bloodadvances.2017014290

PMCID:: PMC6020816

Abstract Article PDF–1.6M

Select item 52909455.

The Phosphatidylinositol 3,4,5-trisphosphate (PI(3,4,5)P₃) Binder Rasa3 Regulates Phosphoinositide 3-kinase (PI3K)-dependent Integrin α_IIbβ₃ Outside-in Signaling

Anthony M. Battram, Tom N. Durrant, Ejaife O. Agbani, Kate J. Heesom, David S. Paul, Raymond Piatt, Alastair W. Poole, Peter J. Cullen, Wolfgang Bergmeier, Samantha F. Moore, Ingeborg Hers

J Biol Chem. 2017 Feb 3; 292(5): 1691–1704. Published online 2016 Nov 30. doi: 10.1074/jbc.M116.746867

PMCID:: PMC5290945

Abstract Article PDF–3.4M

Select item 48500986.

CalDAG-GEFI deficiency reduces atherosclerotic lesion development in mice

Yacine Boulaftali, A. Phillip Owens, III, Ashley Beale, Raymond Piatt, Caterina Casari, Robert H. Lee, Pamela B. Conley, David S. Paul, Nigel Mackman, Wolfgang Bergmeier

Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2017 May 1.

Published in final edited form as: Arterioscler Thromb Vasc Biol. 2016 May; 36(5): 792–799. Published online 2016 Mar 17. doi: 10.1161/ATVBAHA.115.306347

PMCID:: PMC4850098

Abstract Article PDF–1.5M

Select item 47152647.

Integrins form an expanding diffusional barrier that coordinates phagocytosis

Spencer A. Freeman, Jesse Goyette, Wendy Furuya, Elliot C. Woods, Carolyn R. Bertozzi, Wolfgang Bergmeier, Boris Hinz, P. Anton van der Merwe, Raibatak Das, Sergio Grinstein

Cell. Author manuscript; available in PMC 2017 Jan 14.

Published in final edited form as: Cell. 2016 Jan 14; 164(0): 128–140. doi: 10.1016/j.cell.2015.11.048

PMCID:: PMC4715264

Abstract Article PDF–3.7M

Select item 46180868.

The Interleukin-2-mTORc1 Axis Defines the Reciprocal Signaling, Differentiation, and Metabolism of T Helper 1 and Follicular B Helper T Cells

John P. Ray, Matthew M. Staron, Justin A. Shyer, Ping-Chih Ho, Heather D. Marshall, Simon M. Gray, Brian J. Laidlaw, Koichi Araki, Rafi Ahmed, Susan M. Kaech, Joe Craft

Immunity. Author manuscript; available in PMC 2016 Oct 20.

Published in final edited form as: Immunity. 2015 Oct 20; 43(4): 690–702. Published online 2015 Sep 22. doi: 10.1016/j.immuni.2015.08.017

PMCID:: PMC4618086

Abstract Article PDF–2.2M

Select item 46179749.

FoxP1 orchestration of ASD-relevant signaling pathways in the striatum

Daniel J. Araujo, Ashley G. Anderson, Stefano Berto, Wesley Runnels, Matthew Harper, Simon Ammanuel, Michael A. Rieger, Hung-Chung Huang, Kacey Rajkovich, Kristofer W. Loerwald, Joseph D. Dekker, Haley O. Tucker, Joseph D. Dougherty, Jay R. Gibson, Genevieve Konopka

Genes Dev. 2015 Oct 15; 29(20): 2081–2096. doi: 10.1101/gad.267989.115

PMCID:: PMC4617974

Abstract Article PDF–1.3M

Select item 439646210.

RASA3 is a critical inhibitor of RAP1-dependent platelet activation

Lucia Stefanini, David S. Paul, Raymond F. Robledo, E. Ricky Chan, Todd M. Getz, Robert A. Campbell, Daniel O. Kechele, Caterina Casari, Raymond Piatt, Kathleen M. Caron, Nigel Mackman, Andrew S. Weyrich, Matthew C. Parrott, Yacine Boulaftali, Mark D. Adams, Luanne L. Peters, Wolfgang Bergmeier

J Clin Invest. 2015 Apr 1; 125(4): 1419–1432. Published online 2015 Feb 23. doi: 10.1172/JCI77993

PMCID:: PMC4396462

Abstract Article PDF–3.5M

Select item 411241411.

When integrins fail to integrate

Andrés Hidalgo, Paul S. Frenette

Nat Med. Author manuscript; available in PMC 2014 Jul 28.

Published in final edited form as: Nat Med. 2009 Mar; 15(3): 249–250. doi: 10.1038/nm0309-249

PMCID:: PMC4112414

Article PDF–349K

Select item 399975712.

A talin mutant that impairs talin-integrin binding in platelets decelerates αIIbβ3 activation without pathological bleeding

Lucia Stefanini, Feng Ye, Adam K. Snider, Kasra Sarabakhsh, Raymond Piatt, David S. Paul, Wolfgang Bergmeier, Brian G. Petrich

Blood. 2014 Apr 24; 123(17): 2722–2731. Prepublished online 2014 Feb 28. doi: 10.1182/blood-2013-12-543363

PMCID:: PMC3999757

Abstract Article

Select item 355242413.

NOVA-dependent regulation of cryptic NMD exons controls synaptic protein levels after seizure

Taesun Eom, Chaolin Zhang, Huidong Wang, Kenneth Lay, John Fak, Jeffrey L Noebels, Robert B Darnell

eLife. 2013; 2: e00178. Published online 2013 Jan 22. doi: 10.7554/eLife.00178

PMCID:: PMC3552424

Abstract Article PDF–5.5M

Select item 326208514.

Rap1-Rac1 Circuits Potentiate Platelet Activation

Lucia Stefanini, Yacine Boulaftali, Timothy D. Ouellette, Michael Holinstat, Laurent Désiré, Bertrand Leblond, Patrick Andre, Pamela B. Conley, Wolfgang Bergmeier

Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2012 Feb 1.

Published in final edited form as: Arterioscler Thromb Vasc Biol. 2012 Feb; 32(2): 434–441. Published online 2011 Nov 10. doi: 10.1161/ATVBAHA.111.239194

PMCID:: PMC3262085

Abstract Article PDF–1.8M

Select item 318634215.

Histones induce rapid and profound thrombocytopenia in mice

Tobias A. Fuchs, Ashish A. Bhandari, Denisa D. Wagner

Blood. 2011 Sep 29; 118(13): 3708–3714. Prepublished online 2011 Jun 23. doi: 10.1182/blood-2011-01-332676

PMCID:: PMC3186342

Abstract Article

Select item 318435516.

Relative contribution of STIM1 and CalDAG-GEFI to calcium-dependent platelet activation and thrombosis

F. Ahmad, Y. Boulaftali, T. K. Greene, T. D. Ouellette, M. Poncz, S. Feske, W. Bergmeier

J Thromb Haemost. Author manuscript; available in PMC 2012 Oct 1.

Published in final edited form as: J Thromb Haemost. 2011 Oct; 9(10): 2077–2086. doi: 10.1111/j.1538-7836.2011.04474.x

PMCID:: PMC3184355

Abstract Article PDF–2.2M

Select item 317805917.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 314816118.

CalDAG-GEFI deficiency protects mice in a novel model of FcγRIIA-mediated thrombosis and thrombocytopenia

Moritz Stolla, Lucia Stefanini, Pierrette André, Timothy D. Ouellette, Michael P. Reilly, Steven E. McKenzie, Wolfgang Bergmeier

Blood. 2011 Jul 28; 118(4): 1113–1120. Prepublished online 2011 Jun 7. doi: 10.1182/blood-2011-03-342352

PMCID:: PMC3148161

Abstract Article

Select item 312456819.

Rap1a activation by CalDAG-GEFI and p38 MAPK is involved in E-selectin-dependent slow leukocyte rolling

Anika Stadtmann, Laura Brinkhaus, Helena Mueller, Jan Rossaint, Matteo Bolomini-Vittori, Wolfgang Bergmeier, Hugo Van Aken, Denisa D. Wagner, Carlo Laudanna, Klaus Ley, Alexander Zarbock

Eur J Immunol. Author manuscript; available in PMC 2012 Jul 1.

Published in final edited form as: Eur J Immunol. 2011 Jul; 41(7): 2074–2085. Published online 2011 Jun 7. doi: 10.1002/eji.201041196

PMCID:: PMC3124568

Abstract Article PDF–1.7M

Select item 303506320.

The kinetics of αIIbβ3 activation determines the size and stability of thrombi in mice: implications for antiplatelet therapy

Moritz Stolla, Lucia Stefanini, R. Claire Roden, Massiel Chavez, Jessica Hirsch, Teshell Greene, Timothy D. Ouellette, Sean F. Maloney, Scott L. Diamond, Mortimer Poncz, Donna S. Woulfe, Wolfgang Bergmeier

Blood. 2011 Jan 20; 117(3): 1005–1013. Prepublished online 2010 Oct 22. doi: 10.1182/blood-2010-07-297713

PMCID:: PMC3035063

Abstract Article

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