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Items: 1 to 20 of 36

1.
Lipid droplets are a metabolic vulnerability in melanoma
Dianne Lumaquin-Yin, Emily Montal, Eleanor Johns, Arianna Baggiolini, Ting-Hsiang Huang, Yilun Ma, Charlotte LaPlante, Shruthy Suresh, Lorenz Studer, Richard M. White
Nat Commun. 2023; 14: 3192. Published online 2023 Jun 2. doi: 10.1038/s41467-023-38831-9
PMCID:
PMC10238408
AbstractArticlePDF–3.8M
2.
Identifying the Transcriptional Drivers of Metastasis Embedded within Localized Melanoma
Shruthy Suresh, Roy Rabbie, Manik Garg, Dianne Lumaquin, Ting-Hsiang Huang, Emily Montal, Yilun Ma, Nelly M Cruz, Xinran Tang, Jérémie Nsengimana, Julia Newton-Bishop, Miranda V. Hunter, Yuxin Zhu, Kevin Chen, Elisa de Stanchina, David J. Adams, Richard M. White
Cancer Discov. 2023 Jan 9; 13(1): 194–215. Published online 2022 Oct 19. doi: 10.1158/2159-8290.CD-22-0427
PMCID:
PMC9827116
AbstractArticlePDF–67M
3.
An evolutionarily conserved PTEN-C/EBPα-CTNNA1 axis controls myeloid development and transformation
Chun-Tang Fu, Kang-Yong Zhu, Jian-Qing Mi, Yuan-Fang Liu, Susan T. Murray, Yan-Fang Fu, Chun-Guang Ren, Zhi-Wei Dong, Yi-Jie Liu, Mei Dong, Yi Jin, Yi Chen, Min Deng, Wu Zhang, Bin Chen, Peter Breslin, Sai-Juan Chen, Zhu Chen, Michael W. Becker, Jiang Zhu, Ji-Wang Zhang, Ting Xi Liu
Blood. 2010 Jun 10; 115(23): 4715–4724. Prepublished online 2010 Apr 6. doi: 10.1182/blood-2009-11-255778
PMCID:
PMC9728059
AbstractArticle
4.
Top2a promotes the development of social behavior via PRC2 and H3K27me3
Yijie Geng, Tejia Zhang, Ivy G. Alonzo, Sean C. Godar, Christopher Yates, Brock R. Pluimer, Devin L. Harrison, Anjali K. Nath, Jing-Ruey Joanna Yeh, Iain A. Drummond, Marco Bortolato, Randall T. Peterson
Sci Adv. 2022 Nov; 8(47): eabm7069. Published online 2022 Nov 23. doi: 10.1126/sciadv.abm7069
PMCID:
PMC9683714
AbstractArticlePDF–2.4M
5.
Developmental chromatin programs determine oncogenic competence in melanoma
Arianna Baggiolini, Scott J. Callahan, Emily Montal, Joshua M. Weiss, Tuan Trieu, Mohita M. Tagore, Sam E. Tischfield, Ryan M. Walsh, Shruthy Suresh, Yujie Fan, Nathaniel R. Campbell, Sarah C. Perlee, Nathalie Saurat, Miranda V. Hunter, Theresa Simon-Vermot, Ting-Hsiang Huang, Yilun Ma, Travis Hollmann, Satish K. Tickoo, Barry S. Taylor, Ekta Khurana, Richard P. Koche, Lorenz Studer, Richard M. White
Science. Author manuscript; available in PMC 2022 Sep 4.
Published in final edited form as: Science. 2021 Sep 3; 373(6559): eabc1048. Published online 2021 Sep 3. doi: 10.1126/science.abc1048
PMCID:
PMC9440978
AbstractArticlePDF–2.7M
6.
Farnesoid X Receptor Activation Impairs Liver Progenitor Cell–Mediated Liver Regeneration via the PTEN-PI3K-AKT-mTOR Axis in Zebrafish
Kyounghwa Jung, Minwook Kim, Juhoon So, Seung-Hoon Lee, Sungjin Ko, Donghun Shin
Hepatology. Author manuscript; available in PMC 2022 Jul 1.
Published in final edited form as: Hepatology. 2021 Jul; 74(1): 397–410. Published online 2021 Jun 15. doi: 10.1002/hep.31679
PMCID:
PMC8605479
AbstractArticlePDF–2.3M
7.
MicroRNA-21 Plays Multiple Oncometabolic Roles in Colitis-Associated Carcinoma and Colorectal Cancer via the PI3K/AKT, STAT3, and PDCD4/TNF-α Signaling Pathways in Zebrafish
Chi-Yu Lai, Kun-Yun Yeh, Bi-Feng Liu, Tzu-Ming Chang, Chuan-Hsun Chang, Yung-Feng Liao, Yi-Wen Liu, Guor Mour Her
Cancers (Basel) 2021 Nov; 13(21): 5565. Published online 2021 Nov 6. doi: 10.3390/cancers13215565
PMCID:
PMC8583575
AbstractArticlePDF–7.0M
8.
Synergistic melanoma cell death mediated by inhibition of both MCL1 and BCL2 in high-risk tumors driven by NF1/PTEN loss
Shuning He, Mark W. Zimmerman, Hillary M. Layden, Alla Berezovskaya, Julia Etchin, Megan W. Martel, Grace Thurston, Chang-Bin Jing, Ellen van Rooijen, Charles K. Kaufman, Scott J. Rodig, Leonard I. Zon, E. Elizabeth Patton, Marc R. Mansour, A. Thomas Look
Oncogene. 2021; 40(38): 5718–5729. Published online 2021 Jul 30. doi: 10.1038/s41388-021-01926-y
PMCID:
PMC8460449
AbstractArticlePDF–5.8M
9.
Cooperation between liver-specific mutations of pten and tp53 genetically induces hepatocarcinogenesis in zebrafish
Juanjuan Luo, Chunjiao Lu, Meilan Feng, Lu Dai, Maya Wang, Yang Qiu, Huilu Zheng, Yao Liu, Li Li, Bo Tang, Chuan Xu, Yajun Wang, Xiaojun Yang
J Exp Clin Cancer Res. 2021; 40: 262. Published online 2021 Aug 20. doi: 10.1186/s13046-021-02061-y
PMCID:
PMC8377946
AbstractArticlePDF–11M
10.
Phosphatidylinositol-3 kinase signaling controls survival and stemness of hematopoietic stem and progenitor cells
Sasja Blokzijl-Franke, Bas Ponsioen, Stefan Schulte-Merker, Philippe Herbomel, Karima Kissa, Suma Choorapoikayil, Jeroen den Hertog
Oncogene. 2021; 40(15): 2741–2755. Published online 2021 Mar 13. doi: 10.1038/s41388-021-01733-5
PMCID:
PMC8049872
AbstractArticlePDF–4.4M
11.
setd2 knockout zebrafish is viable and fertile: differential and developmental stress-related requirements for Setd2 and histone H3K36 trimethylation in different vertebrate animals
Dian-Jia Liu, Fan Zhang, Yi Chen, Yi Jin, Yuan-Liang Zhang, Shu-Bei Chen, Yin-Yin Xie, Qiu-Hua Huang, Wei-Li Zhao, Lan Wang, Peng-Fei Xu, Zhu Chen, Sai-Juan Chen, Bing Li, Aijun Zhang, Xiao-Jian Sun
Cell Discov. 2020; 6: 72. Published online 2020 Oct 20. doi: 10.1038/s41421-020-00203-8
PMCID:
PMC7573620
AbstractArticlePDF–2.7M
12.
Zebrafish pten Genes Play Relevant but Distinct Roles in Antiviral Immunity
Patricia Pereiro, Antonio Figueras, Beatriz Novoa
Vaccines (Basel) 2020 Jun; 8(2): 199. Published online 2020 Apr 26. doi: 10.3390/vaccines8020199
PMCID:
PMC7349019
AbstractArticlePDF–3.9M
13.
Control of Angiogenesis via a VHL/miR-212/132 Axis
Zhiyong Lei, Timothy D. Klasson, Maarten M. Brandt, Glenn van de Hoek, Ive Logister, Caroline Cheng, Pieter A. Doevendans, Joost P. G. Sluijter, Rachel H. Giles
Cells. 2020 Apr; 9(4): 1017. Published online 2020 Apr 19. doi: 10.3390/cells9041017
PMCID:
PMC7226144
AbstractArticlePDF–5.4M
14.
Loss of PINK1 Function Affects Development and Results in Neurodegeneration in Zebrafish
Oleg Anichtchik, Heike Diekmann, Angeleen Fleming, Alan Roach, Paul Goldsmith, David C. Rubinsztein
J Neurosci. 2008 Aug 13; 28(33): 8199–8207. doi: 10.1523/JNEUROSCI.0979-08.2008
PMCID:
PMC6670558
AbstractArticlePDF–484K
15.
Rapamycin reduces mortality in acute-stage paraquat-induced toxicity in zebrafish
Nan Feng, Zhaolian Bian, Xiaobin Zhang, Changsheng Wang, Jie Chen
Singapore Med J. 2019 May; 60(5): 241–246. doi: 10.11622/smedj.2018132
PMCID:
PMC6535450
AbstractArticlePDF–540K
16.
Human tumor genomics and zebrafish modeling identify SPRED1 loss as a driver of mucosal melanoma
Julien Ablain, Mengshu Xu, Harriet Rothschild, Richard C. Jordan, Jeffrey K. Mito, Brianne H. Daniels, Caitlin F. Bell, Nancy M. Joseph, Hong Wu, Boris C. Bastian, Leonard I. Zon, Iwei Yeh
Science. Author manuscript; available in PMC 2019 Apr 22.
Published in final edited form as: Science. 2018 Nov 30; 362(6418): 1055–1060. Published online 2018 Nov 1. doi: 10.1126/science.aau6509
PMCID:
PMC6475924
AbstractArticlePDF–1.2M
17.
Impaired caudal fin‐fold regeneration in zebrafish deficient for the tumor suppressor Pten
Alexander James Hale, Ali Kiai, Jelte Sikkens, Jeroen den Hertog
Regeneration (Oxf) 2017 Aug; 4(4): 217–226. Published online 2017 Nov 10. doi: 10.1002/reg2.88
PMCID:
PMC5743786
AbstractArticlePDF–2.6M
18.
Oncogenic Role of THOR, a Conserved Cancer/Testis Long Noncoding RNA
Yasuyuki Hosono, Yashar S Niknafs, John R Prensner, Matthew K Iyer, Saravana M Dhanasekaran, Rohit Mehra, Sethuramasundaram Pitchiaya, Jean Tien, June Escara-Wilke, Anton Poliakov, Shih-Chun Chu, Sahal Saleh, Keerthana Sankar, Fengyun Su, Shuling Guo, Yuanyuan Qiao, Susan M Freier, Huynh-Hoa Bui, Xuhong Cao, Rohit Malik, Timothy M Johnson, David G Beer, Felix Y Feng, Weibin Zhou, Arul M Chinnaiyan
Cell. Author manuscript; available in PMC 2018 Dec 14.
Published in final edited form as: Cell. 2017 Dec 14; 171(7): 1559–1572.e20. doi: 10.1016/j.cell.2017.11.040
Correction in:
Cell. 2023 Sep 14; 186(19): 4254–4255.
PMCID:
PMC5734106
AbstractArticlePDF–1.4M
19.
Fine-Tuning of Pten Localization and Phosphatase Activity Is Essential for Zebrafish Angiogenesis
Miriam Stumpf, Sasja Blokzijl-Franke, Jeroen den Hertog
PLoS One. 2016; 11(5): e0154771. Published online 2016 May 3. doi: 10.1371/journal.pone.0154771
PMCID:
PMC4854392
AbstractArticlePDF–3.7M
20.
Differential Requirement for Pten Lipid and Protein Phosphatase Activity during Zebrafish Embryonic Development
Miriam Stumpf, Jeroen den Hertog
PLoS One. 2016; 11(2): e0148508. Published online 2016 Feb 5. doi: 10.1371/journal.pone.0148508
PMCID:
PMC4743836
AbstractArticlePDF–6.0M

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