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Select item 108548341.

Pro-Fibrotic Effects of CCL18 on Human Lung Fibroblasts Are Mediated via CCR6

Kerstin Höhne, Annett Wagenknecht, Corinna Maier, Peggy Engelhard, Torsten Goldmann, Stephan J. Schließmann, Till Plönes, Martin Trepel, Hermann Eibel, Joachim Müller-Quernheim, Gernot Zissel

Cells. 2024 Feb; 13(3): 238. Published online 2024 Jan 26. doi: 10.3390/cells13030238

PMCID:: PMC10854834

Abstract Article PDF–1.7M

Select item 106988212.

Increased gene expression of CCR6 and RORγt in peripheral blood cells of rheumatoid arthritis patients and their correlation with anti‐cyclic citrullinated peptide and disease activity

Seyed Askar Roghani, Ramin Lotfi, Masood Ghasemzade Soroush, Ali Khorasanizadeh, Parisa Feizollahi, Shirin Assar, Parviz Soufivand, Mehran Pournazari, Zahra Mohammadi Kish, Mahdi Taghadosi

Immun Inflamm Dis. 2023 Dec; 11(12): e1112. Published online 2023 Dec 6. doi: 10.1002/iid3.1112

PMCID:: PMC10698821

Abstract Article PDF–757K

Select item 96135093.

SMAD4 suppresses colitis-associated carcinoma through inhibition of CCL20/CCR6-mediated inflammation

David N. Hanna, Paula Marincola Smith, Sergey V. Novitskiy, M. Kay Washington, Jinghuan Zi, Connie J. Weaver, Jalal A. Hamaamen, Keeli B. Lewis, Jing Zhu, Jing Yang, Qi Liu, R. Daniel Beauchamp, Anna L. Means

Gastroenterology. Author manuscript; available in PMC 2023 Nov 1.

Published in final edited form as: Gastroenterology. 2022 Nov; 163(5): 1334–1350.e14. Published online 2022 Jul 19. doi: 10.1053/j.gastro.2022.07.016

PMCID:: PMC9613509

Abstract Article PDF–3.4M

Select item 91529624.

CCR6 activation links innate immune responses to mucosa-associated lymphoid tissue lymphoma development

Boguslawa Korona, Dagmara Korona, Wanfeng Zhao, Andrew C. Wotherspoon, Ming-Qing Du

Haematologica. 2022 Jun 1; 107(6): 1384–1396. Published online 2022 Feb 10. doi: 10.3324/haematol.2021.280067

PMCID:: PMC9152962

Abstract Article PDF–4.9M

Select item 85902335.

Endothelial CCR6 expression due to FLI1 deficiency contributes to vasculopathy associated with systemic sclerosis

Tetsuya Ikawa, Takuya Miyagawa, Yuki Fukui, Satoshi Toyama, Jun Omatsu, Kentaro Awaji, Yuta Norimatsu, Yusuke Watanabe, Ayumi Yoshizaki, Shinichi Sato, Yoshihide Asano

Arthritis Res Ther. 2021; 23: 283. Published online 2021 Nov 13. doi: 10.1186/s13075-021-02667-9

PMCID:: PMC8590233

Abstract Article PDF–1.8M

Select item 85784706.

Human prostate cancer bone metastases have an actionable immunosuppressive microenvironment

Youmna Kfoury, Ninib Baryawno, Nicolas Severe, Shenglin Mei, Karin Gustafsson, Taghreed Hirz, Thomas Brouse, Elizabeth W. Scadden, Anna A. Igolkina, Konstantinos Kokkaliaris, Bryan D. Choi, Nikolas Barkas, Mark A Randolph, John H. Shin, Philip J. Saylor, David T. Scadden, David B. Sykes, Peter V. Kharchenko, Boston Bone Metastases Consortium

Cancer Cell. Author manuscript; available in PMC 2022 Nov 8.

Published in final edited form as: Cancer Cell. 2021 Nov 8; 39(11): 1464–1478.e8. Published online 2021 Oct 15. doi: 10.1016/j.ccell.2021.09.005

PMCID:: PMC8578470

Abstract Article PDF–4.3M

Select item 84192357.

Reduced CCR6⁺IL-17A⁺Treg Cells in Blood and CCR6-Dependent Accumulation of IL-17A⁺Treg Cells in Lungs of Patients With Allergic Asthma

Xiaokun Shen, Huiyun Zhang, Hua Xie, Liping Chen, Shinan Li, Junjuan Zheng, Ruonan Chai, Zhao Wang, Yanyan Zang, Shaoheng He

Front Immunol. 2021; 12: 710750. Published online 2021 Aug 23. doi: 10.3389/fimmu.2021.710750

PMCID:: PMC8419235

Abstract Article PDF–2.8M

Select item 82594368.

Amino terminal recognition by a CCR6 chemokine receptor antibody blocks CCL20 signaling and IL-17 expression via β-arrestin

Sara Gómez-Melero, Fé Isabel García-Maceira, Tania García-Maceira, Verónica Luna-Guerrero, Gracia Montero-Peñalvo, Isaac Túnez-Fiñana, Elier Paz-Rojas

BMC Biotechnol. 2021; 21: 41. Published online 2021 Jul 5. doi: 10.1186/s12896-021-00699-2

PMCID:: PMC8259436

Abstract Article PDF–2.3M

Select item 82502599.

Enrichment of CCR6⁺CD8⁺ T cells and CCL20 in the lungs of mechanically ventilated patients with COVID‐19

Anno Saris, Tom D.Y. Reijnders, Martine Reijm, Jolien C. Hollander, Kim de Buck, Alex R. Schuurman, JanWillem Duitman, Leo Heunks, Jurjan Aman, Harm Jan Bogaard, Esther J. Nossent, Tom van der Poll, Hetty J. Bontkes, Amsterdam UMC COVID study group

Eur J Immunol. 2021 Jun; 51(6): 1535–1538. Published online 2021 May 11. doi: 10.1002/eji.202049046

PMCID:: PMC8250259

Abstract Article PDF–566K

Select item 816503010.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 794697311.

A Functional Variant rs3093023 in CCR6 Is Associated With IgA Nephropathy by Regulating Th17 Cells in a North Han Chinese Population

Yue-miao Zhang, Xing-zi Liu, Xu-jie Zhou, Li-jun Liu, Su-fang Shi, Ping Hou, Ji-cheng Lv, Hong Zhang

Front Immunol. 2021; 12: 600598. Published online 2021 Feb 25. doi: 10.3389/fimmu.2021.600598

PMCID:: PMC7946973

Abstract Article PDF–9.4M

Select item 788924712.

Epigenetic regulation of miR-518a-5p-CCR6 feedback loop promotes both proliferation and invasion in diffuse large B cell lymphoma

Qian Huang, Feng Zhang, Haiying Fu, Jianzhen Shen

Epigenetics. 2021; 16(1): 28–44. Published online 2020 Jun 30. doi: 10.1080/15592294.2020.1786317

PMCID:: PMC7889247

Abstract Article PDF–4.8M

Select item 778000613.

Eomes promotes esophageal carcinoma progression by recruiting Treg cells through the CCL20‐CCR6 pathway

Jingyao Lian, Saisai Liu, Ying Yue, Qingshan Yang, Zhen Zhang, Shengli Yang, Yi Zhang

Cancer Sci. 2021 Jan; 112(1): 144–154. Published online 2020 Nov 17. doi: 10.1111/cas.14712

PMCID:: PMC7780006

Abstract Article PDF–1.5M

Select item 775547014.

Association of RASSF1A, DCR2, and CASP8 Methylation with Survival in Neuroblastoma: A Pooled Analysis Using Reconstructed Individual Patient Data

Waleed M. Hassan, Mohamed S. Bakry, Timo Siepmann, Ben Illigens

Biomed Res Int. 2020; 2020: 7390473. Published online 2020 Dec 15. doi: 10.1155/2020/7390473

PMCID:: PMC7755470

Abstract Article PDF–571K

Select item 729599615.

Structural basis for chemokine receptor CCR6 activation by the endogenous protein ligand CCL20

David Jonathan Wasilko, Zachary Lee Johnson, Mark Ammirati, Ye Che, Matthew C. Griffor, Seungil Han, Huixian Wu

Nat Commun. 2020; 11: 3031. Published online 2020 Jun 15. doi: 10.1038/s41467-020-16820-6

PMCID:: PMC7295996

Abstract Article PDF–1.8M

Select item 713228816.

Evidence for a pathogenic role of extrafollicular, IL-10–producing CCR6⁺B helper T cells in systemic lupus erythematosus

F. Facciotti, P. Larghi, R. Bosotti, C. Vasco, N. Gagliani, C. Cordiglieri, S. Mazzara, V. Ranzani, E. Rottoli, S. Curti, A. Penatti, B. Karnani, Y. Kobayashi, M. Crosti, M. Bombaci, J. P. van Hamburg, G. Rossetti, R. Gualtierotti, M. Gerosa, S. Gatti, S. Torretta, L. Pignataro, S. W. Tas, S. Abrignani, M. Pagani, F. Grassi, P. L. Meroni, R. A. Flavell, J. Geginat

Proc Natl Acad Sci U S A. 2020 Mar 31; 117(13): 7305–7316. Published online 2020 Mar 17. doi: 10.1073/pnas.1917834117

PMCID:: PMC7132288

Abstract Article PDF–2.2M

Select item 677580517.

Clinical significance and prospective molecular mechanism of C-C motif chemokine receptors in patients with early-stage pancreatic ductal adenocarcinoma after pancreaticoduodenectomy

Xin Zhou, Xiwen Liao, Xiangkun Wang, Ketuan Huang, Chengkun Yang, Tingdong Yu, Junqi Liu, Chuangye Han, Guangzhi Zhu, Hao Su, Wei Qin, Quanfa Han, Zhengqian Liu, Jianlv Huang, Yizhen Gong, Xinping Ye, Tao Peng

Oncol Rep. 2019 Nov; 42(5): 1856–1868. Published online 2019 Aug 13. doi: 10.3892/or.2019.7277

PMCID:: PMC6775805

Abstract Article PDF–2.5M

Select item 666787118.

DEPDC1 drives hepatocellular carcinoma cell proliferation, invasion and angiogenesis by regulating the CCL20/CCR6 signaling pathway

Wubin Guo, Hui Li, Huan Liu, Xin Ma, Sijin Yang, Ziwei Wang

Oncol Rep. 2019 Sep; 42(3): 1075–1089. Published online 2019 Jul 5. doi: 10.3892/or.2019.7221

PMCID:: PMC6667871

Abstract Article PDF–3.2M

Select item 636557619.

Differential expression of CXCR3 and CCR6 on CD4⁺ T-lymphocytes with distinct memory phenotypes characterizes tuberculosis-associated immune reconstitution inflammatory syndrome

Paulo S. Silveira-Mattos, Gopalan Narendran, Kevan Akrami, Kiyoshi F. Fukutani, Selvaraj Anbalagan, Kaustuv Nayak, Sudha Subramanyam, Rajasekaran Subramani, Caian L. Vinhaes, Deivide Oliveira-de Souza, Lis R. Antonelli, Kumar Satagopan, Brian O. Porter, Alan Sher, Soumya Swaminathan, Irini Sereti, Bruno B. Andrade

Sci Rep. 2019; 9: 1502. Published online 2019 Feb 6. doi: 10.1038/s41598-018-37846-3

Correction in:: Sci Rep. 2019; 9: 8036.

PMCID:: PMC6365576

Abstract Article PDF–2.7M

Select item 630998820.

Human β-Defensin 2 and 3 and Their Mouse Orthologs Induce Chemotaxis through Interaction with CCR2

Johann Röhrl, De Yang, Joost J. Oppenheim, Thomas Hehlgans

J Immunol. Author manuscript; available in PMC 2018 Dec 28.

Published in final edited form as: J Immunol. 2010 Jun 15; 184(12): 6688–6694. Published online 2010 May 17. doi: 10.4049/jimmunol.0903984

PMCID:: PMC6309988

Abstract Article PDF–1.0M

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