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Items: 1 to 20 of 60

1.
MLF2 Negatively Regulates P53 and Promotes Colorectal Carcinogenesis
Debao Fang, Hao Hu, Kailiang Zhao, Aman Xu, Changjun Yu, Yong Zhu, Ning Yu, Bo Yao, Suyun Tang, Xianning Wu, Yide Mei
Adv Sci (Weinh) 2023 Sep; 10(26): 2303336. Published online 2023 Jul 12. doi: 10.1002/advs.202303336
PMCID:
PMC10502657
AbstractArticlePDF–3.4M
2.
H2B ubiquitination recruits FACT to maintain a stable altered nucleosome state for transcriptional activation
Anfeng Luo, Jingwei Kong, Jun Chen, Xue Xiao, Jie Lan, Xiaorong Li, Cuifang Liu, Peng-Ye Wang, Guohong Li, Wei Li, Ping Chen
Nat Commun. 2023; 14: 741. Published online 2023 Feb 10. doi: 10.1038/s41467-023-36467-3
PMCID:
PMC9918737
AbstractArticlePDF–4.9M
3.
USP21 promotes self-renewal and tumorigenicity of mesenchymal glioblastoma stem cells by deubiquitinating and stabilizing FOXD1
Qixiang Zhang, Zhengxin Chen, Qikai Tang, Zhangjie Wang, Jiacheng Lu, Yongping You, Huibo Wang
Cell Death Dis. 2022 Aug; 13(8): 712. Published online 2022 Aug 16. doi: 10.1038/s41419-022-05163-3
PMCID:
PMC9381540
AbstractArticlePDF–9.6M
4.
OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization
Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti
Science. Author manuscript; available in PMC 2022 Sep 11.
Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983
PMCID:
PMC9119736
AbstractArticlePDF–3.3M
5.
RBM47/SNHG5/FOXO3 axis activates autophagy and inhibits cell proliferation in papillary thyroid carcinoma
Yuan Qin, Wei Sun, Zhihong Wang, Wenwu Dong, Liang He, Ting Zhang, Chengzhou Lv, Hao Zhang
Cell Death Dis. 2022 Mar; 13(3): 270. Published online 2022 Mar 25. doi: 10.1038/s41419-022-04728-6
PMCID:
PMC8956740
AbstractArticlePDF–6.1M
6.
The deubiquitinase OTUD1 inhibits colonic inflammation by suppressing RIPK1-mediated NF-κB signaling
Bo Wu, Lihua Qiang, Yong Zhang, Yesheng Fu, Mengyuan Zhao, Zehui Lei, Zhe Lu, Yan-Ge Wei, Hongmiao Dai, Yingwei Ge, Mingqiu Liu, Xuemei Zhou, Zhiqiang Peng, Hongchang Li, Chun-Ping Cui, Jing Wang, Hui Zheng, Cui Hua Liu, Lingqiang Zhang
Cell Mol Immunol. 2022 Feb; 19(2): 276–289. Published online 2021 Dec 7. doi: 10.1038/s41423-021-00810-9
PMCID:
PMC8803853
AbstractArticlePDF–4.7M
7.
Ablation of USP21 in skeletal muscle promotes oxidative fibre phenotype, inhibiting obesity and type 2 diabetes
Ayoung Kim, Ja Hyun Koo, Xing Jin, Wondong Kim, Shi‐Young Park, Sunghyouk Park, Eugene P. Rhee, Cheol Soo Choi, Sang Geon Kim
J Cachexia Sarcopenia Muscle. 2021 Dec; 12(6): 1669–1689. Published online 2021 Sep 15. doi: 10.1002/jcsm.12777
PMCID:
PMC8718070
AbstractArticlePDF–10M
8.
USP2 is an SKP2 deubiquitylase that stabilizes both SKP2 and its substrates
Fengwu Zhang, Yongchao Zhao, Yi Sun
J Biol Chem. 2021 Oct; 297(4): 101109. Published online 2021 Aug 21. doi: 10.1016/j.jbc.2021.101109
PMCID:
PMC8446802
AbstractArticlePDF–4.0M
9.
Deubiquitinating Enzyme USP21 Inhibits HIV-1 Replication by Downregulating Tat Expression
Wenying Gao, Guangquan Li, Simin Zhao, Hong Wang, Chen Huan, Baisong Zheng, Chunlai Jiang, Wenyan Zhang
J Virol. 2021 Jul; 95(13): e00460-21. Prepublished online 2021 Apr 7. Published online 2021 Jun 10. doi: 10.1128/JVI.00460-21
PMCID:
PMC8316079
AbstractArticlePDF–2.6M
10.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
11.
De-Ubiquitinating Enzymes USP21 Regulate MAPK1 Expression by Binding to Transcription Factor GATA3 to Regulate Tumor Growth and Cell Stemness of Gastric Cancer
Qingqu Guo, Dike Shi, Lele Lin, Hongbo Li, Yunhai Wei, Baozhong Li, Dan Wu
Front Cell Dev Biol. 2021; 9: 641981. Published online 2021 Mar 15. doi: 10.3389/fcell.2021.641981
PMCID:
PMC8005622
AbstractArticlePDF–4.0M
12.
USP21 promotes cell proliferation by maintaining the EZH2 level in diffuse large B‐cell lymphoma
Huixian Ma, Xiangrui Luo, Peng Zhou, Na He, Jun Zhou, Min Liu, Wei Xie
J Clin Lab Anal. 2021 Mar; 35(3): e23693. Published online 2021 Jan 2. doi: 10.1002/jcla.23693
PMCID:
PMC7957995
AbstractArticlePDF–898K
13.
OTUD6A Is an Aurora Kinase A-Specific Deubiquitinase
Hyo Jin Kim, Jongchan Kim
Int J Mol Sci. 2021 Feb; 22(4): 1936. Published online 2021 Feb 16. doi: 10.3390/ijms22041936
PMCID:
PMC7919836
AbstractArticlePDF–5.0M
14.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
15.
A microarray of ubiquitylated proteins for profiling deubiquitylase activity reveals the critical roles of both chain and substrate
Christian M. Loch, James E. Strickler
Biochim Biophys Acta Mol Cell Res. 2012 Nov; 1823(11): 2069–2078. Published online 2012 May 21. doi: 10.1016/j.bbamcr.2012.05.006
PMCID:
PMC7113913
AbstractArticlePDF–1.5M
16.
Distinct regulatory ribosomal ubiquitylation events are reversible and hierarchically organized
Danielle M Garshott, Elayanambi Sundaramoorthy, Marilyn Leonard, Eric J Bennett
eLife. 2020; 9: e54023. Published online 2020 Feb 3. doi: 10.7554/eLife.54023
PMCID:
PMC7064338
AbstractArticlePDF–4.5M
17.
The USP21/YY1/SNHG16 axis contributes to tumor proliferation, migration, and invasion of non-small-cell lung cancer
Pei Xu, Haibo Xiao, Qi Yang, Rui Hu, Lianyong Jiang, Rui Bi, Xueyan Jiang, Lei Wang, Ju Mei, Fangbao Ding, Jianbing Huang
Exp Mol Med. 2020 Jan; 52(1): 41–55. Published online 2020 Jan 20. doi: 10.1038/s12276-019-0356-6
PMCID:
PMC7000404
AbstractArticlePDF–2.9M
18.
USP37 is a SNAI1 deubiquitinase
Zhenna Xiao, Liang Chang, Jongchan Kim, Peijing Zhang, Qinglei Hang, Shannon Yap, Youming Guo, Zhicheng Zhou, Liyong Zeng, Xiaoyu Hu, Ashley Siverly, Yutong Sun, Li Ma
Am J Cancer Res. 2019; 9(12): 2749–2759. Published online 2019 Dec 1.
PMCID:
PMC6943346
AbstractArticlePDF–1.2M
19.
Dual role of a GTPase conformational switch for membrane fusion by mitofusin ubiquitylation
Ramona Schuster, Vincent Anton, Tânia Simões, Selver Altin, Fabian den Brave, Thomas Hermanns, Manuela Hospenthal, David Komander, Gunnar Dittmar, R Jürgen Dohmen, Mafalda Escobar-Henriques
Life Sci Alliance. 2020 Jan; 3(1): e201900476. Published online 2019 Dec 19. doi: 10.26508/lsa.201900476
PMCID:
PMC6925385
AbstractArticlePDF–2.0M
20.
USP21 deubiquitinase promotes pancreas cancer cell stemness via Wnt pathway activation
Pingping Hou, Xingdi Ma, Qiang Zhang, Chang-Jiun Wu, Wenting Liao, Jun Li, Huamin Wang, Jun Zhao, Xin Zhou, Carolyn Guan, Jeffery Ackroyd, Shan Jiang, Jianhua Zhang, Denise J. Spring, Y. Alan Wang, Ronald A. DePinho
Genes Dev. 2019 Oct 1; 33(19-20): 1361–1366. doi: 10.1101/gad.326314.119
PMCID:
PMC6771391
AbstractArticlePDF–4.0M

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