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Items: 1 to 20 of 59

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Functional genomic landscape of cancer-intrinsic evasion of killing by T cells
Keith A. Lawson, Cristovão M. Sousa, Xiaoyu Zhang, Eiru Kim, Rummy Akthar, Joseph J. Caumanns, Yuxi Yao, Nicholas Mikolajewicz, Catherine Ross, Kevin R. Brown, Abdelrahman Abou Zid, Zi Peng Fan, Shirley Hui, Jordan A. Krall, Donald M. Simons, Chloe J. Slater, Victor De Jesus, Lujia Tang, Richa Singh, Joshua E. Goldford, Sarah Martin, Qian Huang, Elizabeth A. Francis, Andrea Habsid, Ryan Climie, David Tieu, Jiarun Wei, Ren Li, Amy Hin Yan Tong, Michael Aregger, Katherine S. Chan, Hong Han, Xiaowei Wang, Patricia Mero, John H. Brumell, Antonio Finelli, Laurie Ailles, Gary Bader, Gromoslaw A. Smolen, Gillian A. Kingsbury, Traver Hart, Charles Kung, Jason Moffat
Nature. Author manuscript; available in PMC 2022 Apr 18.
Published in final edited form as: Nature. 2020 Oct; 586(7827): 120–126. Published online 2020 Sep 23. doi: 10.1038/s41586-020-2746-2
PMCID:
PMC9014559
AbstractArticlePDF–6.6M
3.
Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System
Fatima Memic, Viktoria Knoflach, Khomgrit Morarach, Rebecca Sadler, Catia Laranjeira, Jens Hjerling-Leffler, Erik Sundström, Vassilis Pachnis, Ulrika Marklund
Gastroenterology. 2018 Feb; 154(3): 624–636. doi: 10.1053/j.gastro.2017.10.005
PMCID:
PMC6381388
AbstractArticle
4.
Transcription factor Sp2 potentiates binding of the TALE homeoproteins Pbx1:Prep1 and the histone-fold domain protein Nf-y to composite genomic sites
Sara Völkel, Bastian Stielow, Florian Finkernagel, Dana Berger, Thorsten Stiewe, Andrea Nist, Guntram Suske
J Biol Chem. 2018 Dec 14; 293(50): 19250–19262. Published online 2018 Oct 18. doi: 10.1074/jbc.RA118.005341
PMCID:
PMC6302174
AbstractArticlePDF–2.9M
5.
Prep1 Deficiency Affects Olfactory Perception and Feeding Behavior by Impairing BDNF-TrkB Mediated Neurotrophic Signaling
Serena Ricci, Davide Viggiano, Ilaria Cimmino, Giuseppe Perruolo, Serena Cabaro, Antonietta Liotti, Francesca Fiory, Rosa Spinelli, Angelina Di Carlo, Francesco Beguinot, Pietro Formisano, Francesco Oriente
Mol Neurobiol. 2018; 55(8): 6801–6815. Published online 2018 Jan 18. doi: 10.1007/s12035-018-0873-7
PMCID:
PMC6061220
AbstractArticlePDF–9.7M
6.
Pbx1/Pbx2 govern axial skeletal development by controlling Polycomb and Hox in mesoderm and Pax1/Pax9 in sclerotome
Terence D. Capellini, Rediet Zewdu, Giuseppina Di Giacomo, Stefania Asciutti, Jamie E. Kugler, Anna Di Gregorio, Licia Selleri
Dev Biol. Author manuscript; available in PMC 2018 Apr 26.
Published in final edited form as: Dev Biol. 2008 Sep 15; 321(2): 500–514. Published online 2008 Apr 16. doi: 10.1016/j.ydbio.2008.04.005
PMCID:
PMC5918304
AbstractArticlePDF–4.0M
7.
Germ cell-intrinsic requirement for the homeodomain transcription factor PKnox1/Prep1 in adult spermatogenesis
Yasuhiro Kawai, Akihisa Oda, Yoshiakira Kanai, Ryo Goitsuka
PLoS One. 2018; 13(1): e0190702. Published online 2018 Jan 2. doi: 10.1371/journal.pone.0190702
PMCID:
PMC5749842
AbstractArticlePDF–20M
8.
Prep1 prevents premature adipogenesis of mesenchymal progenitors
Giorgia Maroni, Vsevolod A. Tkachuk, Alexander Egorov, Marco J. Morelli, Raffaele Luongo, Elena Levantini, Francesco Blasi, Maria Cristina Magli, Dmitry Penkov
Sci Rep. 2017; 7: 15573. Published online 2017 Nov 14. doi: 10.1038/s41598-017-15828-1
PMCID:
PMC5686065
AbstractArticlePDF–2.3M
9.
Prep1 (pKnox1)‐deficiency leads to spontaneous tumor development in mice and accelerates EμMyc lymphomagenesis: A tumor suppressor role for Prep1
E. Longobardi, G. Iotti, P. Di Rosa, S. Mejetta, F. Bianchi, L.C. Fernandez-Diaz, N. Micali, P. Nuciforo, E. Lenti, M. Ponzoni, C. Doglioni, M. Caniatti, P.P. Di Fiore, F. Blasi
Mol Oncol. 2010 Apr; 4(2): 126–134. Published online 2010 Jan 7. doi: 10.1016/j.molonc.2010.01.001
PMCID:
PMC5527898
AbstractArticlePDF–1.0M
10.
Loss of the Homeodomain Transcription Factor Prep1 Perturbs Adult Hematopoiesis in the Bone Marrow
Kentaro Yoshioka, Akihisa Oda, Chihiro Notsu, Takafumi Ohtsuka, Yasuhiro Kawai, Sadafumi Suzuki, Takuro Nakamura, Yo Mabuchi, Yumi Matsuzaki, Ryo Goitsuka
PLoS One. 2015; 10(8): e0136107. Published online 2015 Aug 18. doi: 10.1371/journal.pone.0136107
PMCID:
PMC4540428
AbstractArticlePDF–1.9M
11.
ChIP-Seq and RNA-Seq Analyses Identify Components of the Wnt and Fgf Signaling Pathways as Prep1 Target Genes in Mouse Embryonic Stem Cells
Audrey Laurent, Manuela Calabrese, Hans-Jörg Warnatz, Marie-Laure Yaspo, Vsevolod Tkachuk, Miguel Torres, Francesco Blasi, Dmitry Penkov
PLoS One. 2015; 10(4): e0122518. Published online 2015 Apr 13. doi: 10.1371/journal.pone.0122518
PMCID:
PMC4395233
AbstractArticlePDF–1.2M
12.
A high resolution spatiotemporal atlas of gene expression of the developing mouse brain
Carol L. Thompson, Lydia Ng, Vilas Menon, Salvador Martinez, Chang-Kyu Lee, Katie Glattfelder, Susan M. Sunkin, Alex Henry, Christopher Lau, Chinh Dang, Raquel Garcia-Lopez, Almudena Martinez-Ferre, Ana Pombero, John L.R. Rubenstein, Wayne B. Wakeman, John Hohmann, Nick Dee, Andrew J. Sodt, Rob Young, Kimberly Smith, Thuc-Nghi Nguyen, Jolene Kidney, Leonard Kuan, Andreas Jeromin, Ajamete Kaykas, Jeremy Miller, Damon Page, Geri Orta, Amy Bernard, Zackery Riley, Simon Smith, Paul Wohnoutka, Mike Hawrylycz, Luis Puelles, Allan R. Jones
Neuron. Author manuscript; available in PMC 2015 Jul 16.
Published in final edited form as: Neuron. 2014 Jul 16; 83(2): 309–323. Published online 2014 Jun 19. doi: 10.1016/j.neuron.2014.05.033
PMCID:
PMC4319559
AbstractArticlePDF–3.0M
13.
Transcription factor PREP1 induces EMT and metastasis by controlling the TGF-β–SMAD3 pathway in non-small cell lung adenocarcinoma
Maurizio Risolino, Nadia Mandia, Francescopaolo Iavarone, Leila Dardaei, Elena Longobardi, Serena Fernandez, Francesco Talotta, Fabrizio Bianchi, Federica Pisati, Lorenzo Spaggiari, Patrick N. Harter, Michel Mittelbronn, Dorothea Schulte, Mariarosaria Incoronato, Pier Paolo Di Fiore, Francesco Blasi, Pasquale Verde
Proc Natl Acad Sci U S A. 2014 Sep 9; 111(36): E3775–E3784. Published online 2014 Aug 25. doi: 10.1073/pnas.1407074111
PMCID:
PMC4246949
AbstractArticlePDF–1.9M
14.
Prep1 (pKnox1) Regulates Mouse Embryonic HSC Cycling and Self-Renewal Affecting the Stat1-Sca1 IFN-Dependent Pathway
Livia Modica, Giorgio Iotti, Annalisa D’Avola, Francesco Blasi
PLoS One. 2014; 9(9): e107916. Published online 2014 Sep 18. doi: 10.1371/journal.pone.0107916
PMCID:
PMC4169458
AbstractArticlePDF–5.1M
15.
The Deficiency of Tumor Suppressor Prep1 Accelerates the Onset of Meis1- Hoxa9 Leukemogenesis
Leila Dardaei, Livia Modica, Giorgio Iotti, Francesco Blasi
PLoS One. 2014; 9(5): e96711. Published online 2014 May 8. doi: 10.1371/journal.pone.0096711
PMCID:
PMC4014505
AbstractArticlePDF–1.9M
16.
Prep1 and Meis1 competition for Pbx1 binding regulates protein stability and tumorigenesis
Leila Dardaei, Elena Longobardi, Francesco Blasi
Proc Natl Acad Sci U S A. 2014 Mar 11; 111(10): E896–E905. Published online 2014 Feb 27. doi: 10.1073/pnas.1321200111
PMCID:
PMC3956142
AbstractArticlePDF–1.8M
17.
Pknox1/Prep1 Regulates Mitochondrial Oxidative Phosphorylation Components in Skeletal Muscle
Timo Kanzleiter, Michaela Rath, Dmitry Penkov, Dmytro Puchkov, Nadja Schulz, Francesco Blasi, Annette Schürmann
Mol Cell Biol. 2014 Jan; 34(2): 290–298. doi: 10.1128/MCB.01232-13
PMCID:
PMC3911294
AbstractArticlePDF–1.4M
18.
Reduction of Prep1 Levels Affects Differentiation of Normal and Malignant B Cells and Accelerates Myc Driven Lymphomagenesis
Giorgio Iotti, Stefania Mejetta, Livia Modica, Dmitry Penkov, Maurilio Ponzoni, Francesco Blasi
PLoS One. 2012; 7(10): e48353. Published online 2012 Oct 25. doi: 10.1371/journal.pone.0048353
PMCID:
PMC3485025
AbstractArticlePDF–371K
19.
Cohesin regulates tissue-specific expression by stabilizing highly occupied cis-regulatory modules
Andre J. Faure, Dominic Schmidt, Stephen Watt, Petra C. Schwalie, Michael D. Wilson, Huiling Xu, Robert G. Ramsay, Duncan T. Odom, Paul Flicek
Genome Res. 2012 Nov; 22(11): 2163–2175. doi: 10.1101/gr.136507.111
PMCID:
PMC3483546
AbstractArticlePDF–1.2M
20.
A Genome-Wide Screen to Identify Transcription Factors Expressed in Pelvic Ganglia of the Lower Urinary Tract
Carrie B. Wiese, Sara Ireland, Nicole L. Fleming, Jing Yu, M. Todd Valerius, Kylie Georgas, Han Sheng Chiu, Jane Brennan, Jane Armstrong, Melissa H. Little, Andrew P. McMahon, E. Michelle Southard-Smith
Front Neurosci. 2012; 6: 130. Published online 2012 Sep 12. doi: 10.3389/fnins.2012.00130
PMCID:
PMC3439845
AbstractArticlePDF–1.4M

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