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Select item 110351111.

Angiotension II directly bind P2X7 receptor to induce myocardial ferroptosis and remodeling by activating human antigen R

Xin Zhong, Kangwei Wang, Yonghua Wang, Luya Wang, Sudan Wang, Weijian Huang, Zhuyin Jia, Shan-Shan Dai, Zhouqing Huang

Redox Biol. 2024 Jun; 72: 103154. Published online 2024 Apr 9. doi: 10.1016/j.redox.2024.103154

PMCID:: PMC11035111

Abstract Article PDF–19M

Select item 110253162.

SUMOylation controls Hu antigen R posttranscriptional activity in liver cancer

Sofia Lachiondo-Ortega, Claudia M. Rejano-Gordillo, Jorge Simon, Fernando Lopitz-Otsoa, Teresa C. Delgado, Krystyna Mazan-Mamczarz, Naroa Goikoetxea-Usandizaga, L. Estefanía Zapata-Pavas, Ana Garcıía-del Río, Pietro Guerra, Patricia Peña-Sanfélix, Natalia Hermán-Sánchez, Ruba Al-Abdulla, Carmen Fernandez-Rodríguez, Mikel Azkargorta, Alejandro Velázquez-Cruz, Joris Guyon, César Martín, Juan Diego Zalamea, Leire Egia-Mendikute, Arantza Sanz-Parra, Marina Serrano-Maciá, Irene González-Recio, Monika Gonzalez-Lopez, Luis Alfonso Martínez-Cruz, Patrizia Pontisso, Ana M. Aransay, Rosa Barrio, James D. Sutherland, Nicola G.A. Abrescia, Félix Elortza, Amaia Lujambio, Jesus M. Banales, Raúl M. Luque, Manuel D. Gahete, Asıś Palazón, Matias A. Avila, Jose J. G. Marin, Supriyo De, Thomas Daubon, Antonio Díaz-Quintana, Irene Díaz-Moreno, Myriam Gorospe, Manuel S. Rodríguez, María Luz Martínez-Chantar

Cell Rep. Author manuscript; available in PMC 2024 Apr 18.

Published in final edited form as: Cell Rep. 2024 Mar 26; 43(3): 113924. Published online 2024 Mar 18. doi: 10.1016/j.celrep.2024.113924

PMCID:: PMC11025316

Abstract Article PDF–3.2M

Select item 109176603.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 108745814.

HuR promotes castration-resistant prostate cancer progression by altering ERK5 activation via posttranscriptional regulation of BCAT1

Hang You, Guojing Song, Zhizhen Xu, Saipeng Chen, Wenhao Shen, Heting Liu, Bingqian Deng, Jun Li, Gang Huang

J Transl Med. 2024; 22: 178. Published online 2024 Feb 18. doi: 10.1186/s12967-024-04970-w

PMCID:: PMC10874581

Abstract Article PDF–7.9M

Select item 106721665.

Mature mRNA processing that deletes 3′ end sequences directs translational activation and embryonic development

Yuki Takada, Ludivine Fierro, Keisuke Sato, Takahiro Sanada, Anna Ishii, Takehiro Yamamoto, Tomoya Kotani

Sci Adv. 2023 Nov 24; 9(47): eadg6532. Published online 2023 Nov 24. doi: 10.1126/sciadv.adg6532

PMCID:: PMC10672166

Abstract Article PDF–2.2M

Select item 106028776.

Srsf1 and Elavl1 act antagonistically on neuronal fate choice in the developing neocortex by controlling TrkC receptor isoform expression

A Ioana Weber, Srinivas Parthasarathy, Ekaterina Borisova, Ekaterina Epifanova, Marco Preußner, Alexandra Rusanova, Mateusz C Ambrozkiewicz, Paraskevi Bessa, Andrew G Newman, Lisa Müller, Heiner Schaal, Florian Heyd, Victor Tarabykin

Nucleic Acids Res. 2023 Oct 27; 51(19): 10218–10237. Published online 2023 Sep 11. doi: 10.1093/nar/gkad703

Correction in:: Nucleic Acids Res. 2024 Feb 9; 52(3): 1522.

PMCID:: PMC10602877

Abstract Article PDF–2.5M

Select item 105937847.

HuR-mediated nucleocytoplasmic translocation of HOTAIR relieves its inhibition of osteogenic differentiation and promotes bone formation

Yuheng Li, Weijia Sun, Jianwei Li, Ruikai Du, Wenjuan Xing, Xinxin Yuan, Guohui Zhong, Dingsheng Zhao, Zizhong Liu, Xiaoyan Jin, Junjie Pan, Youyou Li, Qi Li, Guanghan Kan, Xuan Han, Shukuan Ling, Xiqing Sun, Yingxian Li

Bone Res. 2023; 11: 53. Published online 2023 Oct 23. doi: 10.1038/s41413-023-00289-2

PMCID:: PMC10593784

Abstract Article PDF–4.7M

Select item 105906898.

Long noncoding RNA 1392 regulates MDA5 by interaction with ELAVL1 to inhibit coxsackievirus B5 infection

Jing Li, Jinwei Li, Peiying Teng, Fan Yang, Jihong Zhang, Bo Sun, Wei Chen

Virol Sin. 2023 Oct; 38(5): 699–708. Published online 2023 Aug 3. doi: 10.1016/j.virs.2023.08.001

PMCID:: PMC10590689

Abstract Article PDF–1.8M

Select item 101104019.

HuR modulation counteracts lipopolysaccharide response in murine macrophages

Isabelle Bonomo, Giulia Assoni, Valeria La Pietra, Giulia Canarutto, Elisa Facen, Greta Donati, Chiara Zucal, Silvia Genovese, Mariachiara Micaelli, Anna Pérez-Ràfols, Sergio Robbiati, Dimitris L. Kontoyannis, Marilenia De Matteo, Marco Fragai, Pierfausto Seneci, Luciana Marinelli, Daniela Arosio, Silvano Piazza, Alessandro Provenzani

Dis Model Mech. 2023 Mar 1; 16(3): dmm050120. Published online 2023 Mar 29. doi: 10.1242/dmm.050120

PMCID:: PMC10110401

Abstract Article

Select item 994366510.

The formation of HuR/YB1 complex is required for the stabilization of target mRNA to promote myogenesis

Brenda Janice Sánchez, Souad Mubaid, Sandrine Busque, Yossef Lopez de los Santos, Kholoud Ashour, Jason Sadek, Xian Jin Lian, Shahryar Khattak, Sergio Di Marco, Imed-Eddine Gallouzi

Nucleic Acids Res. 2023 Feb 22; 51(3): 1375–1392. Published online 2023 Jan 11. doi: 10.1093/nar/gkac1245

PMCID:: PMC9943665

Abstract Article PDF–5.4M

Select item 990032911.

Small noncoding vault RNA2‐1 disrupts gut epithelial barrier function via interaction with HuR

Xiang‐Xue Ma, Lan Xiao, Susan J Wen, Ting‐Xi Yu, Shweta Sharma, Hee K Chung, Bridgette Warner, Caroline G Mallard, Jaladanki N Rao, Myriam Gorospe, Jian‐Ying Wang

EMBO Rep. 2023 Feb; 24(2): e54925. Published online 2022 Nov 28. doi: 10.15252/embr.202254925

PMCID:: PMC9900329

Abstract Article PDF–4.1M

Select item 986807612.

HuR-dependent expression of Wisp1 is necessary for TGFβ-induced cardiac myofibroblast activity

Lisa C Green, Samuel Slone, Sarah R Anthony, Adrienne R Guarnieri, Sharon Parkins, Shannon M Shearer, Michelle L Nieman, Sudeshna Roy, Jeffrey Aube, Xiaoqing Wu, Liang Xu, Onur Kanisicak, Michael Tranter

J Mol Cell Cardiol. Author manuscript; available in PMC 2024 Jan 1.

Published in final edited form as: J Mol Cell Cardiol. 2023 Jan; 174: 38–46. Published online 2022 Nov 11. doi: 10.1016/j.yjmcc.2022.10.007

PMCID:: PMC9868076

Abstract Article PDF–1.3M

Select item 976168313.

The RNA-Binding Protein HuR Is Integral to the Function of Nociceptors in Mice and Humans

Nikesh Kunder, June Bryan de la Peña, Tzu-Fang Lou, Rebecca Chase, Prarthana Suresh, Jennifer Lawson, Tarjani Shukla, Bryan Black, Zachary T. Campbell

J Neurosci. 2022 Dec 7; 42(49): 9129–9141. doi: 10.1523/JNEUROSCI.1630-22.2022

PMCID:: PMC9761683

Abstract Article PDF–2.6M

Select item 969136914.

circHIPK3 prevents cardiac senescence by acting as a scaffold to recruit ubiquitin ligase to degrade HuR

Fengzhi Ding, Lin Lu, Chengjie Wu, Xiangbin Pan, Bin Liu, Yu Zhang, Yanli Wang, Weiliang Wu, Bing Yan, Yuqing Zhang, Xi-Yong Yu, Yangxin Li

Theranostics. 2022; 12(17): 7550–7566. Published online 2022 Oct 31. doi: 10.7150/thno.77630

PMCID:: PMC9691369

Abstract Article PDF–2.7M

Select item 967557515.

Long noncoding RNA uc.230/CUG-binding protein 1 axis sustains intestinal epithelial homeostasis and response to tissue injury

Ting-Xi Yu, Sudhakar Kalakonda, Xiangzheng Liu, Naomi Han, Hee K. Chung, Lan Xiao, Jaladanki N. Rao, Tong-Chuan He, Jean-Pierre Raufman, Jian-Ying Wang

JCI Insight. 2022 Oct 10; 7(19): e156612. Published online 2022 Oct 10. doi: 10.1172/jci.insight.156612

PMCID:: PMC9675575

Abstract Article PDF–14M

Select item 960386016.

The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3

Laura Sánchez-Bellver, Andrea Férriz-Gordillo, Marc Carrillo-Pz, Laura Rabanal, Francesc R. Garcia-Gonzalo, Gemma Marfany

Int J Mol Sci. 2022 Oct; 23(20): 12527. Published online 2022 Oct 19. doi: 10.3390/ijms232012527

PMCID:: PMC9603860

Abstract Article PDF–3.4M

Select item 942500517.

lncRNA MEG3 restrained the M1 polarization of microglia in acute spinal cord injury through the HuR/A20/NF‐κB axis

Heng‐Jun Zhou, Li‐Qing Wang, Ren‐Ya Zhan, Xiu‐Jue Zheng, Jie‐Sheng Zheng

Brain Pathol. 2022 Sep; 32(5): e13070. Published online 2022 Mar 25. doi: 10.1111/bpa.13070

PMCID:: PMC9425005

Abstract Article PDF–9.9M

Select item 931879518.

An interplay between the p38 MAPK pathway and AUBPs regulates c-fos mRNA stability during mitogenic stimulation

Maria Sol Degese, Tamara Tanos, Julian Naipauer, Tim Gingerich, Diego Chiappe, Pablo Echeverria, Jonathan LaMarre, J. Silvio Gutkind, Omar A. Coso

Biochem J. Author manuscript; available in PMC 2022 Jul 26.

Published in final edited form as: Biochem J. 2015 Apr 1; 467(1): 77–90. doi: 10.1042/BJ20141100

PMCID:: PMC9318795

Abstract Article PDF–4.3M

Select item 880294119.

Loss of RNA-Binding Protein HuR Leads to Defective Ependymal Cells and Hydrocephalus

Xiu Han, Xuning Shen, Min Wang, Xin Wang, Youli Jian, Chonglin Yang, Weixiang Guo

J Neurosci. 2022 Jan 12; 42(2): 202–219. doi: 10.1523/JNEUROSCI.1317-21.2021

PMCID:: PMC8802941

Abstract Article PDF–10M

Select item 866356120.

HuR/Cx40 downregulation causes coronary microvascular dysfunction in type 2 diabetes

Rui Si, Jody Tori O. Cabrera, Atsumi Tsuji-Hosokawa, Rui Guo, Makiko Watanabe, Lei Gao, Yun Sok Lee, Jae-Su Moon, Brian T. Scott, Jian Wang, Anthony W. Ashton, Jaladanki N. Rao, Jian-Ying Wang, Jason X.-J. Yuan, Ayako Makino

JCI Insight. 2021 Nov 8; 6(21): e147982. Published online 2021 Nov 8. doi: 10.1172/jci.insight.147982

PMCID:: PMC8663561

Abstract Article PDF–1.6M

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