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Items: 1 to 20 of 26

1.
Protein kinase R is an innate immune sensor of proteotoxic stress via accumulation of cytoplasmic IL-24
Sophia Davidson, Chien-Hsiung Yu, Annemarie Steiner, Frédéric Ebstein, Paul J. Baker, Valentina Jarur-Chamy, Katja Hrovat Schaale, Pawat Laohamonthonkul, Klara Kong, Dale J. Calleja, Cassandra R. Harapas, Katherine R. Balka, Jacob Mitchell, Jacob T. Jackson, Niall D. Geoghegan, Fiona Moghaddas, Kelly L. Rogers, Katrin D. Mayer-Barber, Adriana A. De Jesus, Dominic De Nardo, Benjamin T. Kile, Anthony J. Sadler, M. Cecilia Poli, Elke Krüger, Raphaela Goldbach Mansky, Seth L. Masters
Sci Immunol. Author manuscript; available in PMC 2024 Apr 23.
Published in final edited form as: Sci Immunol. 2022 Feb 11; 7(68): eabi6763. Published online 2022 Feb 11. doi: 10.1126/sciimmunol.abi6763
PMCID:
PMC11036408
AbstractArticlePDF–1.6M
2.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
3.
IL-24 is the key effector of Th9 cell-mediated tumor immunotherapy
Jintong Chen, Yunwei Zhang, Hua Zhang, Mingyue Zhang, He Dong, Tianxue Qin, Sujun Gao, Siqing Wang
iScience. 2023 Sep 15; 26(9): 107531. Published online 2023 Aug 3. doi: 10.1016/j.isci.2023.107531
PMCID:
PMC10480301
AbstractArticlePDF–4.9M
4.
A tissue injury sensing and repair pathway distinct from host pathogen defense
Siqi Liu, Yun Ha Hur, Xin Cai, Qian Cong, Yihao Yang, Chiwei Xu, Angelina M. Bilate, Kevin Andrew Uy Gonzales, S. Martina Parigi, Christopher J. Cowley, Brian Hurwitz, Ji-Dung Luo, Tiffany Tseng, Shiri Gur-Cohen, Megan Sribour, Tatiana Omelchenko, John Levorse, Hilda Amalia Pasolli, Craig B. Thompson, Daniel Mucida, Elaine Fuchs
Cell. Author manuscript; available in PMC 2023 Jul 5.
Published in final edited form as: Cell. 2023 May 11; 186(10): 2127–2143.e22. Published online 2023 Apr 24. doi: 10.1016/j.cell.2023.03.031
PMCID:
PMC10321318
AbstractArticlePDF–2.7M
5.
IL-24 intrinsically regulates Th17 cell pathogenicity in mice
Christopher Sie, Ravi Kant, Christian Peter, Andreas Muschaweckh, Monika Pfaller, Lucy Nirschl, Helena Domínguez Moreno, Tereza Chadimová, Gildas Lepennetier, Tanja Kuhlmann, Rupert Öllinger, Thomas Engleitner, Roland Rad, Thomas Korn
J Exp Med. 2022 Aug 1; 219(8): e20212443. Published online 2022 Jul 12. doi: 10.1084/jem.20212443
PMCID:
PMC9280194
AbstractArticlePDF–5.5M
6.
Interleukin-24 regulates mucosal remodeling in inflammatory bowel diseases
Anna Ónody, Apor Veres-Székely, Domonkos Pap, Réka Rokonay, Beáta Szebeni, Erna Sziksz, Franz Oswald, Gábor Veres, Áron Cseh, Attila J. Szabó, Ádám Vannay
J Transl Med. 2021; 19: 237. Published online 2021 Jun 2. doi: 10.1186/s12967-021-02890-7
PMCID:
PMC8173892
AbstractArticlePDF–8.1M
7.
IL-24 deficiency protects mice against bleomycin-induced pulmonary fibrosis by repressing IL-4-induced M2 program in macrophages
Li-Zong Rao, Yi Wang, Lei Zhang, Guorao Wu, Lu Zhang, Fa-Xi Wang, Long-Min Chen, Fei Sun, Song Jia, Shu Zhang, Qilin Yu, Jiang-Hong Wei, Hui-Ren Lei, Ting Yuan, Jinxiu Li, Xingxu Huang, Bin Cheng, Jianping Zhao, Yongjian Xu, Bi-Wen Mo, Cong-Yi Wang, Huilan Zhang
Cell Death Differ. 2021 Apr; 28(4): 1270–1283. Published online 2020 Nov 3. doi: 10.1038/s41418-020-00650-6
Correction in:
Cell Death Differ. 2021 Oct; 28(10): 2989.
PMCID:
PMC8027679
AbstractArticlePDF–3.6M
8.
Interleukin-24 protects against liver injury in mouse models
Hsiao-Hsuan Wang, Jian-Hao Huang, Min-Hao Sue, Wei-Chih Ho, Yu-Hsiang Hsu, Kung-Chao Chang, Ming-Shi Chang
EBioMedicine. 2021 Feb; 64: 103213. Published online 2021 Jan 25. doi: 10.1016/j.ebiom.2021.103213
PMCID:
PMC7841303
AbstractArticlePDF–5.2M
9.
The Cytokine IL-17A Limits Th17 Pathogenicity via a Negative Feedback Loop Driven by Autocrine Induction of IL-24
Wai Po Chong, Mary J. Mattapallil, Kumarkrishna Raychaudhuri, So Jin Bing, Sihan Wu, Yajie Zhong, WeiWei Wang, Zilin Chen, Phyllis B. Silver, Yingyos Jittayasothorn, Chi-Chao Chan, Jun Chen, Reiko Horai, Rachel R. Caspi
Immunity. 2020 Aug 18; 53(2): 384–397.e5. Published online 2020 Jul 15. doi: 10.1016/j.immuni.2020.06.022
PMCID:
PMC7362799
AbstractArticlePDF–3.8M
10.
Intracellular XBP1-IL-24 axis dismantles cytotoxic unfolded protein response in the liver
Jianye Wang, Bian Hu, Zhicong Zhao, Haiyan Zhang, He Zhang, Zhenjun Zhao, Xiong Ma, Bin Shen, Beicheng Sun, Xingxu Huang, Jiajie Hou, Qiang Xia
Cell Death Dis. 2020 Jan; 11(1): 17. Published online 2020 Jan 6. doi: 10.1038/s41419-019-2209-6
PMCID:
PMC6944701
AbstractArticlePDF–5.4M
11.
Murine astrocytes produce IL-24 and are susceptible to the immunosuppressive effects of this cytokine
Amanda R. Burmeister, M. Brittany Johnson, Jessica J. Yaemmongkol, Ian Marriott
J Neuroinflammation. 2019; 16: 55. Published online 2019 Mar 2. doi: 10.1186/s12974-019-1444-1
PMCID:
PMC6397747
AbstractArticlePDF–1.2M
12.
Cell-specific requirements for STAT proteins and type I IFN receptor signaling discretely regulate IL-24 and IL-10 expression in NK cells and macrophages
Djeneba Dabitao, Christian M. Hedrich, Fengying Wang, Vimvara Vacharathit, Jay H. Bream
J Immunol. Author manuscript; available in PMC 2019 Mar 15.
Published in final edited form as: J Immunol. 2018 Mar 15; 200(6): 2154–2164. Published online 2018 Feb 7. doi: 10.4049/jimmunol.1701340
PMCID:
PMC5840025
AbstractArticlePDF–1.9M
13.
Systematic screening for skin, hair, and nail abnormalities in a large-scale knockout mouse program
John P. Sundberg, Soheil S. Dadras, Kathleen A. Silva, Victoria E. Kennedy, Gaven Garland, Stephen A. Murray, Beth A. Sundberg, Paul N. Schofield, C. Herbert Pratt
PLoS One. 2017; 12(7): e0180682. Published online 2017 Jul 10. doi: 10.1371/journal.pone.0180682
PMCID:
PMC5503261
AbstractArticlePDF–31M
14.
Interleukin-24 Promotes Pseudomonas Aeruginosa Keratitis in C57BL/6 Mouse Corneas
Bing X. Ross, Nan Gao, Xinhan Cui, Theodore J. Standiford, Jianjiang Xu, Fu-shin X. Yu
J Immunol. Author manuscript; available in PMC 2018 May 1.
Published in final edited form as: J Immunol. 2017 May 1; 198(9): 3536–3547. Published online 2017 Mar 22. doi: 10.4049/jimmunol.1602087
PMCID:
PMC5440843
AbstractArticlePDF–826K
15.
High-throughput discovery of novel developmental phenotypes
Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray
Nature. Author manuscript; available in PMC 2017 Mar 14.
Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356
Correction in:
Nature. 2017 Nov 16; 551(7680): 398.
PMCID:
PMC5295821
AbstractArticlePDF–3.0M
16.
IL-22R Ligands IL-20, IL-22, and IL-24 Promote Wound Healing in Diabetic db/db Mice
Ganesh Kolumam, Xiumin Wu, Wyne P. Lee, Jason A. Hackney, Jose Zavala-Solorio, Vineela Gandham, Dimitry M. Danilenko, Puneet Arora, Xiaoting Wang, Wenjun Ouyang
PLoS One. 2017; 12(1): e0170639. Published online 2017 Jan 26. doi: 10.1371/journal.pone.0170639
PMCID:
PMC5268431
AbstractArticlePDF–11M
17.
Suppression of Her2/Neu mammary tumor development in mda-7/IL-24 transgenic mice
You-Jun Li, Guodong Liu, Lei Xia, Xiao Xiao, Jeff C. Liu, Mitchell E. Menezes, Swadesh K. Das, Luni Emdad, Devanand Sarkar, Paul B. Fisher, Michael C. Archer, Eldad Zacksenhaus, Yaacov Ben-David
Oncotarget. 2015 Nov 10; 6(35): 36943–36954. Published online 2015 Oct 9. doi: 10.18632/oncotarget.6046
PMCID:
PMC4741907
AbstractArticlePDF–1.4M
18.
MDA-7/IL-24 functions as a tumor suppressor gene in vivo in transgenic mouse models of breast cancer
Mitchell E. Menezes, Xue-Ning Shen, Swadesh K. Das, Luni Emdad, Chunqing Guo, Fang Yuan, You-Jun Li, Michael C. Archer, Eldad Zacksenhaus, Jolene J. Windle, Mark A. Subler, Yaacov Ben-David, Devanand Sarkar, Xiang-Yang Wang, Paul B. Fisher
Oncotarget. 2015 Nov 10; 6(35): 36928–36942. Published online 2015 Oct 12. doi: 10.18632/oncotarget.6047
PMCID:
PMC4741906
AbstractArticlePDF–16M
19.
The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data
Gautier Koscielny, Gagarine Yaikhom, Vivek Iyer, Terrence F. Meehan, Hugh Morgan, Julian Atienza-Herrero, Andrew Blake, Chao-Kung Chen, Richard Easty, Armida Di Fenza, Tanja Fiegel, Mark Grifiths, Alan Horne, Natasha A. Karp, Natalja Kurbatova, Jeremy C. Mason, Peter Matthews, Darren J. Oakley, Asfand Qazi, Jack Regnart, Ahmad Retha, Luis A. Santos, Duncan J. Sneddon, Jonathan Warren, Henrik Westerberg, Robert J. Wilson, David G. Melvin, Damian Smedley, Steve D. M. Brown, Paul Flicek, William C. Skarnes, Ann-Marie Mallon, Helen Parkinson
Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D802–D809. Published online 2013 Nov 3. doi: 10.1093/nar/gkt977
PMCID:
PMC3964955
AbstractArticlePDF–5.7M
20.
Apogossypol derivative BI-97C1 (Sabutoclax) targeting Mcl-1 sensitizes prostate cancer cells to mda-7/IL-24–mediated toxicity
Rupesh Dash, Belal Azab, Bridget A. Quinn, Xuening Shen, Xiang-Yang Wang, Swadesh K. Das, Mohamed Rahmani, Jun Wei, Michael Hedvat, Paul Dent, Igor P. Dmitriev, David T. Curiel, Steven Grant, Bainan Wu, John L. Stebbins, Maurizio Pellecchia, John C. Reed, Devanand Sarkar, Paul B. Fisher
Proc Natl Acad Sci U S A. 2011 May 24; 108(21): 8785–8790. Published online 2011 May 9. doi: 10.1073/pnas.1100769108
Correction in:
Proc Natl Acad Sci U S A. 2017 May 30; 114(22): E4522–E4523.
PMCID:
PMC3102401
AbstractArticlePDF–1.0M

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