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Items: 1 to 20 of 64

1.
Targeting postsynaptic glutamate receptor scaffolding proteins PSD-95 and PICK1 for obesity treatment
Nicole Fadahunsi, Jonas Petersen, Sophia Metz, Alexander Jakobsen, Cecilie Vad Mathiesen, Alberte Silke Buch-Rasmussen, Nigel Kurgan, Jeppe Kjærgaard Larsen, Rita C. Andersen, Thomas Topilko, Charlotte Svendsen, Mia Apuschkin, Grethe Skovbjerg, Jan Hendrik Schmidt, Grace Houser, Sara Elgaard Jager, Anders Bach, Atul S. Deshmukh, Tuomas O. Kilpeläinen, Kristian Strømgaard, Kenneth L. Madsen, Christoffer Clemmensen
Sci Adv. 2024 Mar 1; 10(9): eadg2636. Published online 2024 Mar 1. doi: 10.1126/sciadv.adg2636
PMCID:
PMC10906926
AbstractArticlePDF–6.4M
2.
Multi-omics study identifies that PICK1 deficiency causes male infertility by inhibiting vesicle trafficking in Sertoli cells
Jing Jin, Kaiqiang Li, Yaoqiang Du, Fang Gao, Zhen Wang, Weixing Li
Reprod Biol Endocrinol. 2023; 21: 114. Published online 2023 Nov 25. doi: 10.1186/s12958-023-01163-w
PMCID:
PMC10675906
AbstractArticlePDF–9.3M
3.
Btbd11 supports cell-type-specific synaptic function
Alexei M. Bygrave, Ayesha Sengupta, Ella P. Jackert, Mehroz Ahmed, Beloved Adenuga, Erik Nelson, Hana L. Goldschmidt, Richard C. Johnson, Haining Zhong, Felix L. Yeh, Morgan Sheng, Richard L. Huganir
Cell Rep. Author manuscript; available in PMC 2023 Oct 23.
Published in final edited form as: Cell Rep. 2023 Jun 27; 42(6): 112591. Published online 2023 May 31. doi: 10.1016/j.celrep.2023.112591
PMCID:
PMC10592477
AbstractArticlePDF–3.6M
4.
A vital role for PICK1 in the differential regulation of metabotropic glutamate receptor internalization and synaptic AMPA receptor endocytosis
Namrata Ramsakha, Prachi Ojha, Subhajit Pal, Sanjeev Routh, Ami Citri, Samarjit Bhattacharyya
J Biol Chem. 2023 Jun; 299(6): 104837. Published online 2023 May 18. doi: 10.1016/j.jbc.2023.104837
PMCID:
PMC10276164
AbstractArticlePDF–3.8M
5.
Truncating PICK1 Variant Identified in Azoospermia Affected Mitochondrial Dysfunction in Knockout Mice
Yao-qiang Du, Chong-yi Shu, Min Zheng, Wei-de Xu, Yue Sun, Lu Shen, Chen Zhang, Yu-xin Zhang, Qian-ni Wang, Kai-qiang Li, Bing-yu Chen, Ke Hao, Jian-xin Lyu, Zhen Wang
Curr Med Sci. 2023; 43(2): 313–323. Published online 2023 Mar 26. doi: 10.1007/s11596-023-2704-y
PMCID:
PMC10040929
AbstractArticlePDF–1.2M
6.
Arhgap22 Disruption Leads to RAC1 Hyperactivity Affecting Hippocampal Glutamatergic Synapses and Cognition in Mice
Anna Longatti, Luisa Ponzoni, Edoardo Moretto, Giorgia Giansante, Norma Lattuada, Maria Nicol Colombo, Maura Francolini, Mariaelvina Sala, Luca Murru, Maria Passafaro
Mol Neurobiol. 2021; 58(12): 6092–6110. Published online 2021 Aug 28. doi: 10.1007/s12035-021-02502-x
PMCID:
PMC8639580
AbstractArticlePDF–2.8M
7.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
8.
PICK1 Deficiency Exacerbates Sepsis-Associated Acute Kidney Injury
Qian Dou, Hang Tong, Yichun Yang, Han Zhang, Hua Gan
Biomed Res Int. 2021; 2021: 9884297. Published online 2021 Jul 8. doi: 10.1155/2021/9884297
Correction in:
Biomed Res Int. 2022; 2022: 9796317.
PMCID:
PMC8285178
AbstractArticlePDF–2.1M
9.
Membrane-Proximal Region of Glutamate Receptor δ2 Subunit Is Critical for Long-Term Depression and Interaction with Protein Interacting with C Kinase 1 in a Cerebellar Purkinje Neuron
Satoshi Yawata, Hiroshi Tsuchida, Mineko Kengaku, Tomoo Hirano
J Neurosci. 2006 Apr 5; 26(14): 3626–3633. doi: 10.1523/JNEUROSCI.4183-05.2006
Correction in:
J Neurosci. 2006 Apr 19; 26(16): 4451.
PMCID:
PMC6674140
AbstractArticlePDF–1.0M
10.
Protein Interacting with C-Kinase 1/Protein Kinase Cα-Mediated Endocytosis Converts Netrin-1-Mediated Repulsion to Attraction
Joseph L. Bartoe, William L. McKenna, Tiffani K. Quan, Benjamin K. Stafford, Jenna A. Moore, Jun Xia, Kogo Takamiya, Richard L. Huganir, Lindsay Hinck
J Neurosci. 2006 Mar 22; 26(12): 3192–3205. doi: 10.1523/JNEUROSCI.3469-05.2006
PMCID:
PMC6674106
AbstractArticlePDF–2.8M
11.
PICK1 and Phosphorylation of the Glutamate Receptor 2 (GluR2) AMPA Receptor Subunit Regulates GluR2 Recycling after NMDA Receptor-Induced Internalization
Da-Ting Lin, Richard L. Huganir
J Neurosci. 2007 Dec 12; 27(50): 13903–13908. doi: 10.1523/JNEUROSCI.1750-07.2007
PMCID:
PMC6673624
AbstractArticlePDF–382K
12.
PICK1–ICA69 Heteromeric BAR Domain Complex Regulates Synaptic Targeting and Surface Expression of AMPA Receptors
Mian Cao, Junyu Xu, Chong Shen, Chuen Kam, Richard L. Huganir, Jun Xia
J Neurosci. 2007 Nov 21; 27(47): 12945–12956. doi: 10.1523/JNEUROSCI.2040-07.2007
PMCID:
PMC6673288
AbstractArticlePDF–777K
13.
Knock-In Mice Lacking the PDZ-Ligand Motif of mGluR7a Show Impaired PKC-Dependent Autoinhibition of Glutamate Release, Spatial Working Memory Deficits, and Increased Susceptibility to Pentylenetetrazol
Chuan-Sheng Zhang, Federica Bertaso, Volker Eulenburg, Mireille Lerner-Natoli, Greta Ann Herin, Liane Bauer, Joel Bockaert, Laurent Fagni, Heinrich Betz, Astrid Scheschonka
J Neurosci. 2008 Aug 20; 28(34): 8604–8614. doi: 10.1523/JNEUROSCI.0628-08.2008
PMCID:
PMC6671056
AbstractArticlePDF–704K
14.
Protein Interacting with C-Kinase 1 Deficiency Impairs Glutathione Synthesis and Increases Oxidative Stress via Reduction of Surface Excitatory Amino Acid Carrier 1
Ya-Nan Wang, Liang Zhou, Yun-Hong Li, Zhen Wang, Ying-Cong Li, Ya-Wen Zhang, Yin Wang, Gang Liu, Ying Shen
J Neurosci. 2015 Apr 22; 35(16): 6429–6443. doi: 10.1523/JNEUROSCI.3966-14.2015
PMCID:
PMC6605220
AbstractArticlePDF–3.8M
15.
Islet-cell autoantigen 69 mediates the antihyperalgesic effects of electroacupuncture on inflammatory pain by regulating spinal glutamate receptor subunit 2 phosphorylation through protein interacting with C-kinase 1 in mice
Kunyuan Han, Anqi Zhang, Yunchang Mo, Tingting Mao, Binbin Ji, Dan Li, Xiuxiu Zhuang, Meizi Qian, Shuangdong Chen, Zhen Wang, Junlu Wang
Pain. 2019 Mar; 160(3): 712–723. Published online 2018 Dec 3. doi: 10.1097/j.pain.0000000000001450
PMCID:
PMC6407810
AbstractArticlePDF–1.1M
16.
PICK1 Deficiency Induces Autophagy Dysfunction via Lysosomal Impairment and Amplifies Sepsis-Induced Acute Lung Injury
Yunchang Mo, Yingying Lou, Anqi Zhang, Jingjing Zhang, Congying Zhu, Bo Zheng, Dan Li, Mingyuan Zhang, Wenjun Jin, Lei Zhang, Junlu Wang
Mediators Inflamm. 2018; 2018: 6757368. Published online 2018 Oct 3. doi: 10.1155/2018/6757368
PMCID:
PMC6192133
AbstractArticlePDF–5.8M
17.
Arc/Arg3.1 has an activity-regulated interaction with PICK1 that results in altered spatial dynamics
Brandee M. S. S. Goo, Bethany J. Sanstrum, Diana Z. Y. Holden, Yi Yu, Nicholas G. James
Sci Rep. 2018; 8: 14675. Published online 2018 Oct 2. doi: 10.1038/s41598-018-32821-4
PMCID:
PMC6168463
AbstractArticlePDF–2.6M
18.
Potent PDZ-Domain PICK1 Inhibitors that Modulate Amyloid Beta-Mediated Synaptic Dysfunction
Edward Y. S. Lin, Laura F. Silvian, Douglas J. Marcotte, Charles C. Banos, Flora Jow, Timothy R. Chan, Robert M. Arduini, Fang Qian, Darren P. Baker, Chris Bergeron, Catherine A. Hession, Richard L. Huganir, Cassandra F. Borenstein, Istvan Enyedy, Jinming Zou, Ellen Rohde, Marion Wittmann, Gnanasambandam Kumaravel, Kenneth J. Rhodes, Robert H. Scannevin, Anthone W. Dunah, Kevin M. Guckian
Sci Rep. 2018; 8: 13438. Published online 2018 Sep 7. doi: 10.1038/s41598-018-31680-3
PMCID:
PMC6128908
AbstractArticlePDF–2.7M
19.
PICK1 inhibits the E3 ubiquitin ligase activity of Parkin and reduces its neuronal protective effect
Jing He, Mengying Xia, Patrick K. K. Yeung, Jiahua Li, Zhifang Li, Kenny K. Chung, Sookja K. Chung, Jun Xia
Proc Natl Acad Sci U S A. 2018 Jul 24; 115(30): E7193–E7201. Published online 2018 Jul 9. doi: 10.1073/pnas.1716506115
PMCID:
PMC6064985
AbstractArticlePDF–1.5M
20.
PICK1 is essential for insulin production and the maintenance of glucose homeostasis
Jia Li, Zhuo Mao, Jiandong Huang, Jun Xia
Mol Biol Cell. 2018 Mar 1; 29(5): 587–596. doi: 10.1091/mbc.E17-03-0204
PMCID:
PMC6004578
AbstractArticlePDF–2.8M

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