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Items: 1 to 20 of 46

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Hindbrain REV-ERB nuclear receptors regulate sensitivity to diet-induced obesity and brown adipose tissue pathophysiology
Lauren N. Woodie, Lily C. Melink, Ahren J. Alberto, Michelle Burrows, Samantha M. Fortin, Calvin C. Chan, Matthew R. Hayes, Mitchell A. Lazar
Mol Metab. 2024 Jan; 79: 101861. Published online 2023 Dec 23. doi: 10.1016/j.molmet.2023.101861
PMCID:
PMC10792761
AbstractArticlePDF–1.5M
3.
Hepatocyte SREBP signaling mediates clock communication within the liver
Dongyin Guan, Hosung Bae, Dishu Zhou, Ying Chen, Chunjie Jiang, Cam Mong La, Yang Xiao, Kun Zhu, Wenxiang Hu, Trang Minh Trinh, Panpan Liu, Ying Xiong, Bishuang Cai, Cholsoon Jang, Mitchell A. Lazar
J Clin Invest. 2023 Apr 17; 133(8): e163018. Published online 2023 Apr 17. doi: 10.1172/JCI163018
PMCID:
PMC10104893
AbstractArticlePDF–1.6M
4.
SR9009 improves heart function after pressure overload independent of cardiac REV-ERB
Hui Li, Shiyang Song, Chih-liang Tien, Lei Qi, Andrea Graves, Eleni Nasiotis, Thomas P. Burris, Yuanbiao Zhao, Zheng Sun, Lilei Zhang
Front Cardiovasc Med. 2022; 9: 952114. Published online 2022 Jul 14. doi: 10.3389/fcvm.2022.952114
PMCID:
PMC9329699
AbstractArticlePDF–3.0M
5.
Myocardial Rev-erb–Mediated Diurnal Metabolic Rhythm and Obesity Paradox
Shiyang Song, Chih-Liang Tien, Hao Cui, Paul Basil, Ningxia Zhu, Yingyun Gong, Wenbo Li, Hui Li, Qiying Fan, Jong Min Choi, Weijia Luo, Yanfeng Xue, Rui Cao, Wenjun Zhou, Andrea R. Ortiz, Brittany Stork, Vatsala Mundra, Nagireddy Putluri, Brian York, Maoping Chu, Jiang Chang, Sung Yun Jung, Liang Xie, Jiangping Song, Lilei Zhang, Zheng Sun
Circulation. 2022 Feb 8; 145(6): 448–464. Published online 2022 Jan 17. doi: 10.1161/CIRCULATIONAHA.121.056076
PMCID:
PMC8812427
AbstractArticlePDF–6.8M
6.
REV-ERB nuclear receptors in the suprachiasmatic nucleus control circadian period and restrict diet-induced obesity
Marine Adlanmerini, Brianna M. Krusen, Hoang C. B. Nguyen, Clare W. Teng, Lauren N. Woodie, Michael C. Tackenberg, Caroline E. Geisler, Jane Gaisinsky, Lindsey C. Peed, Bryce J. Carpenter, Matthew R. Hayes, Mitchell A. Lazar
Sci Adv. 2021 Oct; 7(44): eabh2007. Published online 2021 Oct 27. doi: 10.1126/sciadv.abh2007
PMCID:
PMC8550249
AbstractArticlePDF–3.6M
7.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
8.
Dysregulation of REV-ERBα impairs GABAergic function and promotes epileptic seizures in preclinical models
Tianpeng Zhang, Fangjun Yu, Haiman Xu, Min Chen, Xun Chen, Lianxia Guo, Cui Zhou, Yuting Xu, Fei Wang, Jiandong Yu, Baojian Wu
Nat Commun. 2021; 12: 1216. Published online 2021 Feb 22. doi: 10.1038/s41467-021-21477-w
PMCID:
PMC7900242
AbstractArticlePDF–2.6M
9.
The Hepatocyte Clock and Feeding Control Chronophysiology of Multiple Liver Cell Types
Dongyin Guan, Ying Xiong, Trang Minh Trinh, Yang Xiao, Wenxiang Hu, Chunjie Jiang, Pieterjan Dierickx, Cholsoon Jang, Joshua D. Rabinowitz, Mitchell A. Lazar
Science. Author manuscript; available in PMC 2021 Mar 11.
Published in final edited form as: Science. 2020 Sep 11; 369(6509): 1388–1394. Published online 2020 Jul 30. doi: 10.1126/science.aba8984
PMCID:
PMC7849028
AbstractArticlePDF–1.6M
10.
Hypothalamic REV-ERB nuclear receptors control diurnal food intake and leptin sensitivity in diet-induced obese mice
Marine Adlanmerini, Hoang C.B. Nguyen, Brianna M. Krusen, Clare W. Teng, Caroline E. Geisler, Lindsey C. Peed, Bryce J. Carpenter, Matthew R. Hayes, Mitchell A. Lazar
J Clin Invest. 2021 Jan 4; 131(1): e140424. Published online 2021 Jan 4. doi: 10.1172/JCI140424
PMCID:
PMC7773391
AbstractArticlePDF–5.7M
11.
Time-restricted feeding prevents obesity and metabolic syndrome in mice lacking a circadian clock
Amandine Chaix, Terry Lin, Hiep D Le, Max W Chang, Satchidananda Panda
Cell Metab. Author manuscript; available in PMC 2020 Dec 21.
Published in final edited form as: Cell Metab. 2019 Feb 5; 29(2): 303–319.e4. Published online 2018 Aug 30. doi: 10.1016/j.cmet.2018.08.004
PMCID:
PMC7751278
AbstractArticlePDF–3.3M
12.
Pharmacological modulation and genetic deletion of REV-ERBα and REV-ERBβ regulates dendritic cell development
Mohammed Amir, Sean Campbell, Theodore M. Kamenecka, Laura A. Solt
Biochem Biophys Res Commun. Author manuscript; available in PMC 2021 Jul 5.
Published in final edited form as: Biochem Biophys Res Commun. 2020 Jul 5; 527(4): 1000–1007. Published online 2020 May 18. doi: 10.1016/j.bbrc.2020.05.012
PMCID:
PMC7339779
AbstractArticlePDF–1.3M
13.
Rev-erbα Negatively Regulates Osteoclast and Osteoblast Differentiation through p38 MAPK Signaling Pathway
Kabsun Kim, Jung Ha Kim, Inyoung Kim, Semun Seong, Nacksung Kim
Mol Cells. 2020 Jan; 43(1): 34–47. Published online 2020 Jan 3. doi: 10.14348/molcells.2019.0232
PMCID:
PMC6999712
AbstractArticlePDF–7.9M
14.
Inhibition of REV‐ERBs stimulates microglial amyloid‐beta clearance and reduces amyloid plaque deposition in the 5XFAD mouse model of Alzheimer’s disease
Jiyeon Lee, Do Eon Kim, Percy Griffin, Patrick W. Sheehan, Dong‐Hou Kim, Erik S Musiek, Seung‐Yong Yoon
Aging Cell. 2020 Feb; 19(2): e13078. Published online 2019 Dec 4. doi: 10.1111/acel.13078
PMCID:
PMC6996949
AbstractArticlePDF–1.8M
15.
The circadian clock protein REVERBα inhibits pulmonary fibrosis development
Peter S. Cunningham, Peter Meijer, Alicja Nazgiewicz, Simon G. Anderson, Lee A. Borthwick, James Bagnall, Gareth B. Kitchen, Monika Lodyga, Nicola Begley, Rajamiyer V. Venkateswaran, Rajesh Shah, Paul F. Mercer, Hannah J. Durrington, Neil C. Henderson, Karen Piper-Hanley, Andrew J. Fisher, Rachel C. Chambers, David A. Bechtold, Julie E. Gibbs, Andrew S. Loudon, Martin K. Rutter, Boris Hinz, David W. Ray, John F. Blaikley
Proc Natl Acad Sci U S A. 2020 Jan 14; 117(2): 1139–1147. Published online 2019 Dec 26. doi: 10.1073/pnas.1912109117
PMCID:
PMC6969503
AbstractArticlePDF–2.0M
16.
Circadian rhythm-dependent and circadian rhythm-independent impacts of the molecular clock on type 3 innate lymphoid cells
Qianli Wang, Michelle L. Robinette, Cyrielle Billon, Patrick L. Collins, Jennifer K. Bando, José Luís Fachi, Cristiane Sécca, Sofia I. Porter, Ankita Saini, Susan Gilfillan, Laura A. Solt, Erik S. Musiek, Eugene M. Oltz, Thomas P. Burris, Marco Colonna
Sci Immunol. Author manuscript; available in PMC 2020 Apr 4.
Published in final edited form as: Sci Immunol. 2019 Oct 4; 4(40): eaay7501. doi: 10.1126/sciimmunol.aay7501
PMCID:
PMC6911370
AbstractArticlePDF–1.1M
17.
Circadian lipid synthesis in brown fat maintains murine body temperature during chronic cold
Marine Adlanmerini, Bryce J. Carpenter, Jarrett R. Remsberg, Yann Aubert, Lindsey C. Peed, Hannah J. Richter, Mitchell A. Lazar
Proc Natl Acad Sci U S A. 2019 Sep 10; 116(37): 18691–18699. Published online 2019 Aug 26. doi: 10.1073/pnas.1909883116
PMCID:
PMC6744860
AbstractArticlePDF–1.3M
18.
The nuclear receptor REV-ERBα modulates Th17 cell-mediated autoimmune disease
Christina Chang, Chin-San Loo, Xuan Zhao, Laura A. Solt, Yuqiong Liang, Sagar P. Bapat, Han Cho, Theodore M. Kamenecka, Mathias Leblanc, Annette R. Atkins, Ruth T. Yu, Michael Downes, Thomas P. Burris, Ronald M. Evans, Ye Zheng
Proc Natl Acad Sci U S A. 2019 Sep 10; 116(37): 18528–18536. Published online 2019 Aug 27. doi: 10.1073/pnas.1907563116
PMCID:
PMC6744854
AbstractArticlePDF–1.3M
19.
REV-ERBα and REV-ERBβ function as key factors regulating Mammalian Circadian Output
Ryosuke Ikeda, Yoshiki Tsuchiya, Nobuya Koike, Yasuhiro Umemura, Hitoshi Inokawa, Ryutaro Ono, Maho Inoue, Yuh Sasawaki, Tess Grieten, Naoki Okubo, Kazuya Ikoma, Hiroyoshi Fujiwara, Toshikazu Kubo, Kazuhiro Yagita
Sci Rep. 2019; 9: 10171. Published online 2019 Jul 15. doi: 10.1038/s41598-019-46656-0
PMCID:
PMC6629614
AbstractArticlePDF–1.5M
20.
SR9009 has REV-ERB–independent effects on cell proliferation and metabolism
Pieterjan Dierickx, Matthew J. Emmett, Chunjie Jiang, Kahealani Uehara, Manlu Liu, Marine Adlanmerini, Mitchell A. Lazar
Proc Natl Acad Sci U S A. 2019 Jun 18; 116(25): 12147–12152. Published online 2019 May 24. doi: 10.1073/pnas.1904226116
PMCID:
PMC6589768
AbstractArticlePDF–1.2M

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