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Items: 1 to 20 of 39

1.
Inhibition of CERS1 in skeletal muscle exacerbates age-related muscle dysfunction
Martin Wohlwend, Pirkka-Pekka Laurila, Ludger JE Goeminne, Tanes Lima, Ioanna Daskalaki, Xiaoxu Li, Giacomo von Alvensleben, Barbara Crisol, Renata Mangione, Hector Gallart-Ayala, Amélia Lalou, Olivier Burri, Stephen Butler, Jonathan Morris, Nigel Turner, Julijana Ivanisevic, Johan Auwerx
eLife. 2024; 12: RP90522. Published online 2024 Mar 20. doi: 10.7554/eLife.90522
Correction in:
eLife. 2024; 13: e99846.
PMCID:
PMC10954306
AbstractArticlePDF–3.8M
2.
Regulation of meiotic telomere dynamics through membrane fluidity promoted by AdipoR2-ELOVL2
Jingjing Zhang, Mario Ruiz, Per-Olof Bergh, Marcus Henricsson, Nena Stojanović, Ranjan Devkota, Marius Henn, Mohammad Bohlooly-Y, Abrahan Hernández-Hernández, Manfred Alsheimer, Jan Borén, Marc Pilon, Hiroki Shibuya
Nat Commun. 2024; 15: 2315. Published online 2024 Mar 14. doi: 10.1038/s41467-024-46718-6
PMCID:
PMC10940294
AbstractArticlePDF–6.0M
3.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
4.
CerS1 but Not CerS5 Gene Silencing, Improves Insulin Sensitivity and Glucose Uptake in Skeletal Muscle
Agnieszka U. Błachnio-Zabielska, Kamila Roszczyc-Owsiejczuk, Monika Imierska, Karolina Pogodzińska, Paweł Rogalski, Jarosław Daniluk, Piotr Zabielski
Cells. 2022 Jan; 11(2): 206. Published online 2022 Jan 8. doi: 10.3390/cells11020206
PMCID:
PMC8773817
AbstractArticlePDF–3.5M
5.
Growth differentiation factor 1-induced tumour plasticity provides a therapeutic window for immunotherapy in hepatocellular carcinoma
Wei Cheng, Hao-Long Li, Shao-Yan Xi, Xiao-Feng Zhang, Yun Zhu, Le Xing, Yan-Xuan Mo, Mei-Mei Li, Fan-En Kong, Wen-Jie Zhu, Xiao-Gang Chen, Hui-Qing Cui, Zhi-Ming Cao, Yuan-Feng Gong, Yun-Qiang Tang, Yan Zhang, Xin-Yuan Guan, Ning-Fang Ma, Ming Liu
Nat Commun. 2021; 12: 7142. Published online 2021 Dec 8. doi: 10.1038/s41467-021-27525-9
PMCID:
PMC8654996
AbstractArticlePDF–12M
6.
Downregulation of ceramide synthase 1 promotes oral cancer through endoplasmic reticulum stress
Wen Chen, Chenzhou Wu, Yafei Chen, Yuhao Guo, Ling Qiu, Zhe Liu, Haibin Sun, Siyu Chen, Zijian An, Zhuoyuan Zhang, Yi Li, Longjiang Li
Int J Oral Sci. 2021; 13: 10. Published online 2021 Mar 22. doi: 10.1038/s41368-021-00118-4
PMCID:
PMC7985500
AbstractArticlePDF–2.3M
7.
ALK4 coordinates extracellular and intrinsic signals to regulate development of cortical somatostatin interneurons
Christina Göngrich, Favio A. Krapacher, Hermany Munguba, Diana Fernández-Suárez, Annika Andersson, Jens Hjerling-Leffler, Carlos F. Ibáñez
J Cell Biol. 2020 Jan 6; 219(1): e201905002. Published online 2019 Nov 1. doi: 10.1083/jcb.201905002
PMCID:
PMC7039195
AbstractArticlePDF–5.9M
8.
Tbx6 controls left-right asymmetry through regulation of Gdf1
Daniel Concepcion, Hiroshi Hamada, Virginia E. Papaioannou
Biol Open. 2018 May 15; 7(5): bio032565. Published online 2018 Apr 12. doi: 10.1242/bio.032565
PMCID:
PMC5992533
AbstractArticlePDF–6.1M
9.
Ectopic expression of ceramide synthase 2 in neurons suppresses neurodegeneration induced by ceramide synthase 1 deficiency
Stefka D. Spassieva, Xiaojie Ji, Ye Liu, Kenneth Gable, Jacek Bielawski, Teresa M. Dunn, Erhard Bieberich, Lihong Zhao
Proc Natl Acad Sci U S A. 2016 May 24; 113(21): 5928–5933. Published online 2016 May 9. doi: 10.1073/pnas.1522071113
PMCID:
PMC4889366
AbstractArticlePDF–1.6M
10.
SIRT3 Deacetylates Ceramide Synthases: IMPLICATIONS FOR MITOCHONDRIAL DYSFUNCTION AND BRAIN INJURY
Sergei A. Novgorodov, Christopher L. Riley, Jarryd A. Keffler, Jin Yu, Mark S. Kindy, Wendy B. Macklin, David B. Lombard, Tatyana I. Gudz
J Biol Chem. 2016 Jan 22; 291(4): 1957–1973. Published online 2015 Nov 30. doi: 10.1074/jbc.M115.668228
PMCID:
PMC4722471
AbstractArticlePDF–2.0M
11.
A high resolution spatiotemporal atlas of gene expression of the developing mouse brain
Carol L. Thompson, Lydia Ng, Vilas Menon, Salvador Martinez, Chang-Kyu Lee, Katie Glattfelder, Susan M. Sunkin, Alex Henry, Christopher Lau, Chinh Dang, Raquel Garcia-Lopez, Almudena Martinez-Ferre, Ana Pombero, John L.R. Rubenstein, Wayne B. Wakeman, John Hohmann, Nick Dee, Andrew J. Sodt, Rob Young, Kimberly Smith, Thuc-Nghi Nguyen, Jolene Kidney, Leonard Kuan, Andreas Jeromin, Ajamete Kaykas, Jeremy Miller, Damon Page, Geri Orta, Amy Bernard, Zackery Riley, Simon Smith, Paul Wohnoutka, Mike Hawrylycz, Luis Puelles, Allan R. Jones
Neuron. Author manuscript; available in PMC 2015 Jul 16.
Published in final edited form as: Neuron. 2014 Jul 16; 83(2): 309–323. Published online 2014 Jun 19. doi: 10.1016/j.neuron.2014.05.033
PMCID:
PMC4319559
AbstractArticlePDF–3.0M
12.
Nature and extent of left/right axis defects in TWis/TWis mutant mouse embryos
Daniel Concepcion, Virginia E. Papaioannou
Dev Dyn. Author manuscript; available in PMC 2015 Aug 1.
Published in final edited form as: Dev Dyn. 2014 Aug; 243(8): 1046–1053. Published online 2014 May 26. doi: 10.1002/dvdy.24144
PMCID:
PMC4238287
AbstractArticlePDF–1.8M
13.
Nodal·Gdf1 Heterodimers with Bound Prodomains Enable Serum-independent Nodal Signaling and Endoderm Differentiation
Christophe Fuerer, M. Cristina Nostro, Daniel B. Constam
J Biol Chem. 2014 Jun 20; 289(25): 17854–17871. Published online 2014 May 5. doi: 10.1074/jbc.M114.550301
PMCID:
PMC4067217
AbstractArticlePDF–5.9M
14.
The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data
Gautier Koscielny, Gagarine Yaikhom, Vivek Iyer, Terrence F. Meehan, Hugh Morgan, Julian Atienza-Herrero, Andrew Blake, Chao-Kung Chen, Richard Easty, Armida Di Fenza, Tanja Fiegel, Mark Grifiths, Alan Horne, Natasha A. Karp, Natalja Kurbatova, Jeremy C. Mason, Peter Matthews, Darren J. Oakley, Asfand Qazi, Jack Regnart, Ahmad Retha, Luis A. Santos, Duncan J. Sneddon, Jonathan Warren, Henrik Westerberg, Robert J. Wilson, David G. Melvin, Damian Smedley, Steve D. M. Brown, Paul Flicek, William C. Skarnes, Ann-Marie Mallon, Helen Parkinson
Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D802–D809. Published online 2013 Nov 3. doi: 10.1093/nar/gkt977
PMCID:
PMC3964955
AbstractArticlePDF–5.7M
15.
Oxidized Phospholipids Induce Ceramide Accumulation in RAW 264.7 Macrophages: Role of Ceramide Synthases
Lingaraju M. Halasiddappa, Harald Koefeler, Anthony H. Futerman, Albin Hermetter
PLoS One. 2013; 8(7): e70002. Published online 2013 Jul 31. doi: 10.1371/journal.pone.0070002
PMCID:
PMC3729465
AbstractArticlePDF–729K
16.
Cilia at the node of mouse embryos sense fluid flow for left-right determination via Pkd2
Satoko Yoshiba, Hidetaka Shiratori, Ivana Y. Kuo, Aiko Kawasumi, Kyosuke Shinohara, Shigenori Nonaka, Yasuko Asai, Genta Sasaki, Jose Antonio Belo, Hiroshi Sasaki, Junichi Nakai, Bernd Dworniczak, Barbara E. Ehrlich, Petra Pennekamp, Hiroshi Hamada
Science. Author manuscript; available in PMC 2013 Jul 15.
Published in final edited form as: Science. 2012 Oct 12; 338(6104): 226–231. Published online 2012 Sep 13. doi: 10.1126/science.1222538
PMCID:
PMC3711115
AbstractArticlePDF–2.0M
17.
Transcription factor Ctip2 controls epidermal lipid metabolism and regulates expression of genes involved in sphingolipid biosynthesis during skin development
Zhixing Wang, Jay S. Kirkwood, Alan W. Taylor, Jan F. Stevens, Mark Leid, Gitali Ganguli-Indra, Arup K. Indra
J Invest Dermatol. Author manuscript; available in PMC 2013 Sep 1.
Published in final edited form as: J Invest Dermatol. 2013 Mar; 133(3): 668–676. Published online 2012 Oct 25. doi: 10.1038/jid.2012.358
PMCID:
PMC3556343
AbstractArticlePDF–608K
18.
Ablation of Neuronal Ceramide Synthase 1 in Mice Decreases Ganglioside Levels and Expression of Myelin-associated Glycoprotein in Oligodendrocytes
Christina Ginkel, Dieter Hartmann, Katharina vom Dorp, Armin Zlomuzica, Hany Farwanah, Matthias Eckhardt, Roger Sandhoff, Joachim Degen, Mariona Rabionet, Ekrem Dere, Peter Dörmann, Konrad Sandhoff, Klaus Willecke
J Biol Chem. 2012 Dec 7; 287(50): 41888–41902. Published online 2012 Oct 16. doi: 10.1074/jbc.M112.413500
PMCID:
PMC3516736
AbstractArticlePDF–2.1M
19.
Gut endoderm is involved in the transfer of left-right asymmetry from the node to the lateral plate mesoderm in the mouse embryo
Ranajeet S. Saund, Masami Kanai-Azuma, Yoshiakira Kanai, Injune Kim, Mary T. Lucero, Yukio Saijoh
Development. 2012 Jul 1; 139(13): 2426–2435. doi: 10.1242/dev.079921
PMCID:
PMC3367449
AbstractArticle
20.
Congenital Asplenia in Mice and Humans with Mutations in a Pbx/Nkx2-5/p15 Module
Matthew Koss, Alexandre Bolze, Andrea Brendolan, Matilde Saggese, Terence D. Capellini, Ekaterina Bojilova, Bertrand Boisson, Owen W.J. Prall, David Elliott, Mark Solloway, Elisa Lenti, Chisa Hidaka, Ching-Pin Chang, Nizar Mahlaoui, Richard P. Harvey, Jean-Laurent Casanova, Licia Selleri
Dev Cell. Author manuscript; available in PMC 2013 May 15.
Published in final edited form as: Dev Cell. 2012 May 15; 22(5): 913–926. Published online 2012 May 3. doi: 10.1016/j.devcel.2012.02.009
PMCID:
PMC3356505
AbstractArticlePDF–6.8M

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