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Items: 1 to 20 of 62

1.
Inhibition of ADORA3 promotes microglial phagocytosis and alleviates chronic ischemic white matter injury
Yuhao Xu, Limoran Tang, Chao Zhou, Liang Sun, Yujie Hu, Zhi Zhang, Shengnan Xia, Xinyu Bao, Haiyan Yang, Yun Xu
CNS Neurosci Ther. 2024 May; 30(5): e14742. Published online 2024 May 7. doi: 10.1111/cns.14742
PMCID:
PMC11076989
AbstractArticlePDF–20M
2.
Targeted deletion of adenosine A3 receptors augments adenosine-induced coronary flow in isolated mouse heart
M. A. HASSAN TALUKDER, R. RAY MORRISON, MARLENE A. JACOBSON, KENNETH A. JACOBSON, CATHERINE LEDENT, S. JAMAL MUSTAFA
Am J Physiol Heart Circ Physiol. Author manuscript; available in PMC 2024 Jan 9.
Published in final edited form as: Am J Physiol Heart Circ Physiol. 2002 Jun; 282(6): H2183–H2189. doi: 10.1152/ajpheart.00964.2001
PMCID:
PMC10775950
AbstractArticlePDF–644K
3.
The Histamine H4 Receptor Participates in the Anti-Neuropathic Effect of the Adenosine A3 Receptor Agonist IB-MECA: Role of CD4+ T Cells
Laura Micheli, Mariaconcetta Durante, Elena Lucarini, Silvia Sgambellone, Laura Lucarini, Lorenzo Di Cesare Mannelli, Carla Ghelardini, Emanuela Masini
Biomolecules. 2021 Oct; 11(10): 1447. Published online 2021 Oct 2. doi: 10.3390/biom11101447
PMCID:
PMC8533073
AbstractArticlePDF–1.7M
4.
Genetic ablation of adenosine receptor A3 results in articular cartilage degeneration
Ruzanna Shkhyan, Siyoung Lee, Francesca Gullo, Lei Li, Maria Peleli, Mattias Carlstrom, Andrei S. Chagin, Nicholas W. Banks, Sean Limfat, Nancy Q. Liu, Denis Evseenko
J Mol Med (Berl) Author manuscript; available in PMC 2021 Oct 6.
Published in final edited form as: J Mol Med (Berl). 2018 Oct; 96(10): 1049–1060. Published online 2018 Aug 7. doi: 10.1007/s00109-018-1680-3
PMCID:
PMC8493638
AbstractArticlePDF–1.7M
5.
Dual Actions of A2A and A3 Adenosine Receptor Ligand Prevents Obstruction-Induced Kidney Fibrosis in Mice
Eun Seon Pak, Lak Shin Jeong, Xiyan Hou, Sushil K. Tripathi, Jiyoun Lee, Hunjoo Ha
Int J Mol Sci. 2021 Jun; 22(11): 5667. Published online 2021 May 26. doi: 10.3390/ijms22115667
PMCID:
PMC8198234
AbstractArticlePDF–3.6M
6.
Adenosine A3 agonists reverse neuropathic pain via T cell–mediated production of IL-10
Mariaconcetta Durante, Silvia Squillace, Filomena Lauro, Luigino Antonio Giancotti, Elisabetta Coppi, Federica Cherchi, Lorenzo Di Cesare Mannelli, Carla Ghelardini, Grant Kolar, Carrie Wahlman, Adeleye Opejin, Cuiying Xiao, Marc L. Reitman, Dilip K. Tosh, Daniel Hawiger, Kenneth A. Jacobson, Daniela Salvemini
J Clin Invest. 2021 Apr 1; 131(7): e139299. Published online 2021 Apr 1. doi: 10.1172/JCI139299
PMCID:
PMC8011899
AbstractArticlePDF–1.9M
7.
Adenosine A2A and A3 Receptors Are Able to Interact with Each Other. A Further Piece in the Puzzle of Adenosine Receptor-Mediated Signaling
Alejandro Lillo, Eva Martínez-Pinilla, Irene Reyes-Resina, Gemma Navarro, Rafael Franco
Int J Mol Sci. 2020 Jul; 21(14): 5070. Published online 2020 Jul 17. doi: 10.3390/ijms21145070
PMCID:
PMC7404137
AbstractArticlePDF–1.5M
8.
Calreticulin haploinsufficiency augments stem cell activity and is required for onset of myeloproliferative neoplasms in mice
Kotaro Shide, Takuro Kameda, Ayako Kamiunten, Yoshinori Ozono, Yuki Tahira, Takako Yokomizo-Nakano, Sho Kubota, Masaya Ono, Kazuhiko Ikeda, Masaaki Sekine, Keiichi Akizuki, Kenichi Nakamura, Tomonori Hidaka, Yoko Kubuki, Hisayoshi Iwakiri, Satoru Hasuike, Kenji Nagata, Goro Sashida, Kazuya Shimoda
Blood. 2020 Jul 2; 136(1): 106–118. Prepublished online 2020 Mar 27. doi: 10.1182/blood.2019003358
PMCID:
PMC7332892
AbstractArticle
9.
The A3 adenosine receptor agonist, namodenoson, ameliorates non-alcoholic steatohepatitis in mice
Pnina Fishman, Shira Cohen, Inbal Itzhak, Johnny Amer, Ahmad Salhab, Faina Barer, Rifaat Safadi
Int J Mol Med. 2019 Dec; 44(6): 2256–2264. Published online 2019 Oct 3. doi: 10.3892/ijmm.2019.4364
PMCID:
PMC6844636
AbstractArticlePDF–753K
10.
CXCL16 Orchestrates Adenosine A3 Receptor and MCP-1/CCL2 Activity to Protect Neurons from Excitotoxic Cell Death in the CNS
Maria Rosito, Cristina Deflorio, Cristina Limatola, Flavia Trettel
J Neurosci. 2012 Feb 29; 32(9): 3154–3163. doi: 10.1523/JNEUROSCI.4046-11.2012
PMCID:
PMC6622038
AbstractArticlePDF–1.7M
11.
Physiology and effects of nucleosides in mice lacking all four adenosine receptors
Cuiying Xiao, Naili Liu, Kenneth A. Jacobson, Oksana Gavrilova, Marc L. Reitman
PLoS Biol. 2019 Mar; 17(3): e3000161. Published online 2019 Mar 1. doi: 10.1371/journal.pbio.3000161
PMCID:
PMC6415873
AbstractArticlePDF–9.2M
12.
Protective roles of adenosine A1, A2A, and A3 receptors in skeletal muscle ischemia and reperfusion injury
Jingang Zheng, Rubio Wang, Edward Zambraski, Dan Wu, Kenneth A. Jacobson, Bruce T. Liang
Am J Physiol Heart Circ Physiol. Author manuscript; available in PMC 2018 Dec 28.
Published in final edited form as: Am J Physiol Heart Circ Physiol. 2007 Dec; 293(6): H3685–H3691. Published online 2007 Oct 5. doi: 10.1152/ajpheart.00819.2007
PMCID:
PMC6309900
AbstractArticlePDF–935K
13.
Beneficial Role of Erythrocyte Adenosine A2B Receptor-Mediated AMPK Activation in High Altitude Hypoxia
Hong Liu, Yujin Zhang, Hongyu Wu, Angelo D’Alessandro, Gennady G. Yegutkin, Anren Song, Kaiqi Sun, Jessica Li, Ning-Yuan Cheng, Aji Huang, Yuan Edward Wen, Ting Ting Weng, Fayong Luo, Travis Nemkov, Hong Sun, Rodney E. Kellems, Harry Karmouty-Quintana, Kirk C. Hansen, Bihong Zhao, Andrew W. Subudhi, Sonja Jameson-Van Houten, Colleen G. Julian, Andrew T. Lovering, Holger K. Eltzschig, Michael R Blackburn, Robert C. Roach, Yang Xia
Circulation. Author manuscript; available in PMC 2018 Oct 2.
Published in final edited form as: Circulation. 2016 Aug 2; 134(5): 405–421. doi: 10.1161/CIRCULATIONAHA.116.021311
PMCID:
PMC6168195
AbstractArticlePDF–1.9M
14.
Adenosine receptors differentially regulate type 2 cytokine production by IL-33–activated bone marrow cells, ILC2s, and macrophages
Balázs Csóka, Zoltán H. Németh, Claudia U. Duerr, Jörg H. Fritz, Pál Pacher, György Haskó
FASEB J. 2018 Feb; 32(2): 829–837. Published online 2017 Oct 5. doi: 10.1096/fj.201700770R
PMCID:
PMC5888397
AbstractArticle
15.
Calreticulin mutant mice develop essential thrombocythemia that is ameliorated by the JAK inhibitor ruxolitinib
K Shide, T Kameda, T Yamaji, M Sekine, N Inada, A Kamiunten, K Akizuki, K Nakamura, T Hidaka, Y Kubuki, H Shimoda, A Kitanaka, A Honda, A Sawaguchi, H Abe, T Miike, H Iwakiri, Y Tahara, M Sueta, S Hasuike, S Yamamoto, K Nagata, K Shimoda
Leukemia. 2017 May; 31(5): 1136–1144. Prepublished online 2016 Nov 3. Published online 2016 Nov 29. doi: 10.1038/leu.2016.308
PMCID:
PMC5420793
AbstractArticlePDF–1.2M
16.
Erythrocytes retain hypoxic adenosine response for faster acclimatization upon re-ascent
Anren Song, Yujin Zhang, Leng Han, Gennady G. Yegutkin, Hong Liu, Kaiqi Sun, Angelo D'Alessandro, Jessica Li, Harry Karmouty-Quintana, Takayuki Iriyama, Tingting Weng, Shushan Zhao, Wei Wang, Hongyu Wu, Travis Nemkov, Andrew W. Subudhi, Sonja Jameson-Van Houten, Colleen G. Julian, Andrew T. Lovering, Kirk C. Hansen, Hong Zhang, Mikhail Bogdanov, William Dowhan, Jianping Jin, Rodney E. Kellems, Holger K. Eltzschig, Michael Blackburn, Robert C. Roach, Yang Xia
Nat Commun. 2017; 8: 14108. Published online 2017 Feb 7. doi: 10.1038/ncomms14108
PMCID:
PMC5309698
AbstractArticlePDF–1.4M
17.
Resetting microbiota by Lactobacillus reuteri inhibits T reg deficiency–induced autoimmunity via adenosine A2A receptors
Baokun He, Thomas K. Hoang, Ting Wang, Michael Ferris, Christopher M. Taylor, Xiangjun Tian, Meng Luo, Dat Q. Tran, Jain Zhou, Nina Tatevian, Fayong Luo, Jose G. Molina, Michael R. Blackburn, Thomas H. Gomez, Stefan Roos, J. Marc Rhoads, Yuying Liu
J Exp Med. 2017 Jan; 214(1): 107–123. doi: 10.1084/jem.20160961
PMCID:
PMC5206500
AbstractArticlePDF–3.2M
18.
Hypothermia in mouse is caused by adenosine A1 and A3 receptor agonists and AMP via three distinct mechanisms
Jesse Lea Carlin, Shalini Jain, Elizabeth Gizewski, Tina C. Wan, Dilip K. Tosh, Cuiying Xiao, John A. Auchampach, Kenneth A. Jacobson, Oksana Gavrilova, Marc L. Reitman
Neuropharmacology. Author manuscript; available in PMC 2018 Mar 1.
Published in final edited form as: Neuropharmacology. 2017 Mar 1; 114: 101–113. Published online 2016 Nov 30. doi: 10.1016/j.neuropharm.2016.11.026
PMCID:
PMC5183552
AbstractArticlePDF–4.3M
19.
Genetic Abrogation of Adenosine A3 Receptor Prevents Uninephrectomy and High Salt–Induced Hypertension
Ting Yang, Christa Zollbrecht, Malin E. Winerdal, Zhengbing Zhuge, Xing‐Mei Zhang, Niccolo Terrando, Antonio Checa, Johan Sällström, Craig E. Wheelock, Ola Winqvist, Robert A. Harris, Erik Larsson, A. Erik G. Persson, Bertil B. Fredholm, Mattias Carlström
J Am Heart Assoc. 2016 Jul; 5(7): e003868. Published online 2016 Jul 18. doi: 10.1161/JAHA.116.003868
PMCID:
PMC5015411
AbstractArticlePDF–4.8M
20.
Detrimental effects of adenosine signaling in sickle cell disease
Yujin Zhang, Yingbo Dai, Jiaming Wen, Weiru Zhang, Almut Grenz, Hong Sun, Lijian Tao, Guangxiu Lu, Danny C Alexander, Michael V Milburn, Louvenia Carter-Dawson, Dorothy E Lewis, Wenzheng Zhang, Holger K Eltzschig, Rodney E Kellems, Michael R Blackburn, Harinder S Juneja, Yang Xia
Nat Med. Author manuscript; available in PMC 2016 Apr 20.
Published in final edited form as: Nat Med. 2011 Jan; 17(1): 79–86. Published online 2010 Dec 19. doi: 10.1038/nm.2280
PMCID:
PMC4838392
AbstractArticlePDF–556K

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