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Select item 110146571.

A BMP-controlled metabolic/epigenetic signaling cascade directs midfacial morphogenesis

Jingwen Yang, Lingxin Zhu, Haichun Pan, Hiroki Ueharu, Masako Toda, Qian Yang, Shawn A. Hallett, Lorin E. Olson, Yuji Mishina

J Clin Invest. 2024 Apr 15; 134(8): e165787. Published online 2024 Mar 11. doi: 10.1172/JCI165787

PMCID:: PMC11014657

Abstract Article PDF–16M

Select item 109464402.

Sall4 regulates posterior trunk mesoderm development by promoting mesodermal gene expression and repressing neural genes in the mesoderm

Matthew P. Pappas, Hiroko Kawakami, Dylan Corcoran, Katherine Q. Chen, Earl Parker Scott, Julia Wong, Micah D. Gearhart, Ryuichi Nishinakamura, Yasushi Nakagawa, Yasuhiko Kawakami

Development. 2024 Mar 1; 151(5): dev202649. Published online 2024 Mar 4. doi: 10.1242/dev.202649

PMCID:: PMC10946440

Abstract Article

Select item 108179063.

Loss of Pax3 causes reduction of melanocytes in the developing mouse cochlea

Tomokatsu Udagawa, Erisa Takahashi, Norifumi Tatsumi, Hideki Mutai, Hiroki Saijo, Yuko Kondo, Patrick J. Atkinson, Tatsuo Matsunaga, Mamoru Yoshikawa, Hiromi Kojima, Masataka Okabe, Alan G. Cheng

Sci Rep. 2024; 14: 2210. Published online 2024 Jan 26. doi: 10.1038/s41598-024-52629-9

PMCID:: PMC10817906

Abstract Article PDF–7.8M

Select item 107275064.

Age-associated changes in lineage composition of the enteric nervous system regulate gut health and disease

Subhash Kulkarni, Monalee Saha, Jared Slosberg, Alpana Singh, Sushma Nagaraj, Laren Becker, Chengxiu Zhang, Alicia Bukowski, Zhuolun Wang, Guosheng Liu, Jenna M Leser, Mithra Kumar, Shriya Bakhshi, Matthew J Anderson, Mark Lewandoski, Elizabeth Vincent, Loyal A Goff, Pankaj Jay Pasricha

eLife. 2023; 12: RP88051. Published online 2023 Dec 18. doi: 10.7554/eLife.88051

PMCID:: PMC10727506

Abstract Article PDF–13M

Select item 107211865.

Supraclavicular brown adipocytes originate from Tbx1⁺ myoprogenitors

Zan Huang, Chenxin Gu, Zengdi Zhang, Rini Arianti, Aneesh Swaminathan, Kevin Tran, Alex Battist, Endre Kristóf, Hai-Bin Ruan

PLoS Biol. 2023 Dec; 21(12): e3002413. Published online 2023 Dec 4. doi: 10.1371/journal.pbio.3002413

PMCID:: PMC10721186

Abstract Article PDF–3.7M

Select item 106948646.

Pax3 lineage-specific deletion of Gpr161 is associated with spinal neural tube and craniofacial malformations during embryonic development

Sung-Eun Kim, Pooja J. Chothani, Rehana Shaik, Westley Pollard, Richard H. Finnell

Dis Model Mech. 2023 Nov 1; 16(11): dmm050277. Published online 2023 Nov 28. doi: 10.1242/dmm.050277

PMCID:: PMC10694864

Abstract Article

Select item 106518587.

PAX3-FOXO1 dictates myogenic reprogramming and rhabdomyosarcoma identity in endothelial progenitors

Madeline B. Searcy, Randolph K. Larsen, IV, Bradley T. Stevens, Yang Zhang, Hongjian Jin, Catherine J. Drummond, Casey G. Langdon, Katherine E. Gadek, Kyna Vuong, Kristin B. Reed, Matthew R. Garcia, Beisi Xu, Darden W. Kimbrough, Grace E. Adkins, Nadhir Djekidel, Shaina N. Porter, Patrick A. Schreiner, Shondra M. Pruett-Miller, Brian J. Abraham, Jerold E. Rehg, Mark E. Hatley

Nat Commun. 2023; 14: 7291. Published online 2023 Nov 15. doi: 10.1038/s41467-023-43044-1

PMCID:: PMC10651858

Abstract Article PDF–7.8M

Select item 106176258.

Caudal Fgfr1 disruption produces localised spinal mis-patterning and a terminal myelocystocele-like phenotype in mice

Eirini Maniou, Faduma Farah, Abigail R. Marshall, Zoe Crane-Smith, Andrea Krstevski, Athanasia Stathopoulou, Nicholas D. E. Greene, Andrew J. Copp, Gabriel L. Galea

Development. 2023 Oct 1; 150(19): dev202139. Published online 2023 Oct 10. doi: 10.1242/dev.202139

PMCID:: PMC10617625

Abstract Article

Select item 104819469.

The loop-tail mouse model displays open and closed caudal neural tube defects

Beatriz Fernández-Santos, Marta Reyes-Corral, José Manuel Caro-Vega, Miguel Lao-Pérez, Claudia Vallejo-Grijalba, Cristina Mesa-Cruz, Francisco J. Morón, Patricia Ybot-González

Dis Model Mech. 2023 Aug 1; 16(8): dmm050175. Published online 2023 Aug 29. doi: 10.1242/dmm.050175

PMCID:: PMC10481946

Abstract Article

Select item 1033593710.

Spatiotemporal transcriptomic maps of whole mouse embryos at the onset of organogenesis

Abhishek Sampath Kumar, Luyi Tian, Adriano Bolondi, Amèlia Aragonés Hernández, Robert Stickels, Helene Kretzmer, Evan Murray, Lars Wittler, Maria Walther, Gabriel Barakat, Leah Haut, Yechiel Elkabetz, Evan Z. Macosko, Léo Guignard, Fei Chen, Alexander Meissner

Nat Genet. 2023; 55(7): 1176–1185. Published online 2023 Jul 6. doi: 10.1038/s41588-023-01435-6

PMCID:: PMC10335937

Abstract Article PDF–25M

Select item 1026673611.

Yap controls notochord formation and neural tube patterning by integrating mechanotransduction with FoxA2 and Shh expression

Caiqi Cheng, Qian Cong, Yuchen Liu, Yizhong Hu, Guoyan Liang, Kevin Marc Manquiquis Dioneda, Yingzi Yang

Sci Adv. 2023 Jun; 9(24): eadf6927. Published online 2023 Jun 14. doi: 10.1126/sciadv.adf6927

PMCID:: PMC10266736

Abstract Article PDF–2.4M

Select item 1026668112.

Overlapping functions of SIX homeoproteins during embryonic myogenesis

Maud Wurmser, Rouba Madani, Nathalie Chaverot, Stéphanie Backer, Matthew Borok, Matthieu Dos Santos, Glenda Comai, Shahragim Tajbakhsh, Frédéric Relaix, Marc Santolini, Ramkumar Sambasivan, Rulang Jiang, Pascal Maire

PLoS Genet. 2023 Jun; 19(6): e1010781. Published online 2023 Jun 2. doi: 10.1371/journal.pgen.1010781

PMCID:: PMC10266681

Abstract Article PDF–4.6M

Select item 1025366713.

The Midbrain Preisthmus: A Poorly Known Effect of the Isthmic Organizer

Luis Puelles, Matias Hidalgo-Sánchez

Int J Mol Sci. 2023 Jun; 24(11): 9769. Published online 2023 Jun 5. doi: 10.3390/ijms24119769

PMCID:: PMC10253667

Abstract Article PDF–6.8M

Select item 1014872714.

ETS1 loss in mice impairs cardiac outflow tract septation via a cell migration defect autonomous to the neural crest

Lizhu Lin, Antonella Pinto, Lu Wang, Kazumi Fukatsu, Yan Yin, Simon D Bamforth, Marianne E Bronner, Sylvia M Evans, Shuyi Nie, Robert H Anderson, Alexey V Terskikh, Paul D Grossfeld

Hum Mol Genet. 2022 Dec 15; 31(24): 4217–4227. Published online 2022 Jul 28. doi: 10.1093/hmg/ddac174

PMCID:: PMC10148727

Abstract Article PDF–2.2M

Select item 1007300915.

Dual mechanism underlying failure of neural tube closure in the Zic2 mutant mouse

Sarah Escuin, Saba Rose Raza-Knight, Dawn Savery, Carles Gaston-Massuet, Gabriel L. Galea, Nicholas D. E. Greene, Andrew J. Copp

Dis Model Mech. 2023 Mar 1; 16(3): dmm049858. Published online 2023 Mar 14. doi: 10.1242/dmm.049858

PMCID:: PMC10073009

Abstract Article

Select item 998870316.

Single-Cell Characterization of the Frizzled 5 (Fz5) Mutant Mouse and Human Persistent Fetal Vasculature (PFV)

Yuanyuan Chen, Cheng Wu, Shanzhen Peng, Dianlei Guo, Hong Ouyang, Yanhong Wei, Rong Ju, Xiaoyan Ding, Zhi Xie, Chunqiao Liu

Invest Ophthalmol Vis Sci. 2023 Mar; 64(3): 8. Published online 2023 Mar 3. doi: 10.1167/iovs.64.3.8

PMCID:: PMC9988703

Abstract Article PDF–13M

Select item 996398317.

Post-transcriptional regulation in cranial neural crest cells expands developmental potential

Rachel A. Keuls, Young Sun Oh, Ivanshi Patel, Ronald J. Parchem

Proc Natl Acad Sci U S A. 2023 Feb 7; 120(6): e2212578120. Published online 2023 Feb 1. doi: 10.1073/pnas.2212578120

PMCID:: PMC9963983

Abstract Article PDF–6.8M

Select item 967485318.

Biasing the conformation of ELMO2 reveals that myoblast fusion can be exploited to improve muscle regeneration

Viviane Tran, Sarah Nahlé, Amélie Robert, Inès Desanlis, Ryan Killoran, Sophie Ehresmann, Marie-Pier Thibault, David Barford, Kodi S. Ravichandran, Martin Sauvageau, Matthew J. Smith, Marie Kmita, Jean-François Côté

Nat Commun. 2022; 13: 7077. Published online 2022 Nov 18. doi: 10.1038/s41467-022-34806-4

PMCID:: PMC9674853

Abstract Article PDF–3.6M

Select item 962426219.

Endothelial loss of ETS1 impairs coronary vascular development and leads to ventricular non-compaction

Lu Wang, Lizhu Lin, Hui Qi, Ju Chen, Paul Grossfeld

Circ Res. Author manuscript; available in PMC 2023 Aug 19.

Published in final edited form as: Circ Res. 2022 Aug 19; 131(5): 371–387. Published online 2022 Jul 27. doi: 10.1161/CIRCRESAHA.121.319955

PMCID:: PMC9624262

Abstract Article PDF–4.5M

Select item 960130520.

Single Cell Sequencing Reveals Mechanisms of Persistent Truncus Arteriosus Formation after PDGFRα and PDGFRβ Double Knockout in Cardiac Neural Crest Cells

Tianyun Chen, Shen Song, Haobin Jiang, Hong Lian, Shengshou Hu

Genes (Basel) 2022 Oct; 13(10): 1708. Published online 2022 Sep 23. doi: 10.3390/genes13101708

PMCID:: PMC9601305

Abstract Article PDF–8.1M

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