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Select item 110961761.

Proteostatic reactivation of the developmental transcription factor TBX3 drives BRAF/MAPK-mediated tumorigenesis

Zhenlei Zhang, Yufan Wu, Jinrong Fu, Xiujie Yu, Yang Su, Shikai Jia, Huili Cheng, Yan Shen, Xianghui He, Kai Ren, Xiangqian Zheng, Haixia Guan, Feng Rao, Li Zhao

Nat Commun. 2024; 15: 4108. Published online 2024 May 15. doi: 10.1038/s41467-024-48173-9

Correction in:: Nat Commun. 2024; 15: 4936.

PMCID:: PMC11096176

Abstract Article PDF–5.7M

Select item 110167582.

A LTB₄/CD11b self-amplifying loop drives pyogranuloma formation in chronic granulomatous disease

Kelsey C. Haist, Sophie L. Gibbings, Jordan Jacobelli, Kara J. Mould, Peter M. Henson, Donna L. Bratton

iScience. 2024 Apr 19; 27(4): 109589. Published online 2024 Mar 27. doi: 10.1016/j.isci.2024.109589

PMCID:: PMC11016758

Abstract Article PDF–5.3M

Select item 107108753.

Androgen receptor inhibition suppresses anti-tumor neutrophil response against bone metastatic prostate cancer via regulation of TβRI expression

Massar Alsamraae, Diane Costanzo-Garvey, Benjamin A. Teply, Shawna Boyle, Gary Sommerville, Zachary T. Herbert, Colm Morrissey, Alicia J. Dafferner, Maher Y. Abdalla, Rachel W. Fallet, Tammy Kielian, Heather Jensen-Smith, Edson I. deOliveira, Keqiang Chen, Ian A. Bettencourt, Ji Ming Wang, Daniel W. McVicar, Tyler Keeley, Fang Yu, Leah M. Cook

Cancer Lett. Author manuscript; available in PMC 2024 Nov 28.

Published in final edited form as: Cancer Lett. 2023 Nov 28; 579: 216468. Published online 2023 Nov 7. doi: 10.1016/j.canlet.2023.216468

PMCID:: PMC10710875

Abstract Article PDF–2.1M

Select item 105976304.

Mitochondrial pannexin1 controls cardiac sensitivity to ischaemia/reperfusion injury

Olga M Rusiecka, Filippo Molica, Morten S Nielsen, Axel Tollance, Sandrine Morel, Maud Frieden, Marc Chanson, Kerstin Boengler, Brenda R Kwak

Cardiovasc Res. 2023 Sep; 119(13): 2342–2354. Published online 2023 Aug 9. doi: 10.1093/cvr/cvad120

PMCID:: PMC10597630

Abstract Article PDF–990K

Select item 105580895.

Neutrophils Resist Ferroptosis and Promote Breast Cancer Metastasis through Aconitate Decarboxylase 1

Yun Zhao, Zhongshun Liu, Guoqiang Liu, Yuting Zhang, Sheng Liu, Dailin Gan, Wennan Chang, Xiaoxia Peng, Eun Suh Sung, Keegan Gilbert, Yini Zhu, Xuechun Wang, Ziyu Zeng, Hope Baldwin, Guanzhu Ren, Jessica Weaver, Anna Huron, Toni Mayberry, Qingfei Wang, Yujue Wang, Maria Elena Diaz-Rubio, Xiaoyang Su, M. Sharon Stack, Siyuan Zhang, Xuemin Lu, Ryan D. Sheldon, Jun Li, Chi Zhang, Jun Wan, Xin Lu

Cell Metab. Author manuscript; available in PMC 2024 Oct 3.

Published in final edited form as: Cell Metab. 2023 Oct 3; 35(10): 1688–1703.e10. doi: 10.1016/j.cmet.2023.09.004

PMCID:: PMC10558089

Abstract Article PDF–2.8M

Select item 104507956.

Trained immunity of alveolar macrophages enhances injury resolution via KLF4-MERTK-mediated efferocytosis

Sreeparna Chakraborty, Abhalaxmi Singh, Li Wang, Xinge Wang, Mark A. Sanborn, Zijing Ye, Mark Maienschein-Cline, Amitabha Mukhopadhyay, Balaji B. Ganesh, Asrar B. Malik, Jalees Rehman

J Exp Med. 2023 Nov 6; 220(11): e20221388. Published online 2023 Aug 24. doi: 10.1084/jem.20221388

PMCID:: PMC10450795

Abstract Article PDF–8.3M

Select item 102262657.

Experimental hepatic encephalopathy causes early but sustained glial transcriptional changes

Wouter Claeys, Lien Van Hoecke, Hannah Lernout, Clint De Nolf, Griet Van Imschoot, Elien Van Wonterghem, Daan Verhaege, Jonas Castelein, Anja Geerts, Christophe Van Steenkiste, Roosmarijn E. Vandenbroucke

J Neuroinflammation. 2023; 20: 130. Published online 2023 May 29. doi: 10.1186/s12974-023-02814-w

PMCID:: PMC10226265

Abstract Article PDF–6.4M

Select item 101786748.

Depletion of Ly6G-Expressing Neutrophilic Cells Leads to Altered Peripheral T-Cell Homeostasis and Thymic Development in Neonatal Mice

Jessica Rühle, Marco Ginzel, Stefanie Dietz, Julian Schwarz, Trim Lajqi, Sandra Beer-Hammer, Christian F. Poets, Christian Gille, Natascha Köstlin-Gille

Int J Mol Sci. 2023 May; 24(9): 7763. Published online 2023 Apr 24. doi: 10.3390/ijms24097763

PMCID:: PMC10178674

Abstract Article PDF–2.4M

Select item 101481669.

Macrophages in the synovial lining niche initiate neutrophil recruitment and articular inflammation

Kristina Zec, Barbora Schonfeldova, Zhichao Ai, Erinke Van Grinsven, Gabriela Pirgova, Hayley L. Eames, Dorothée L. Berthold, Moustafa Attar, Ewoud B. Compeer, Tal I. Arnon, Irina A. Udalova

J Exp Med. 2023 Aug 7; 220(8): e20220595. Published online 2023 Apr 28. doi: 10.1084/jem.20220595

PMCID:: PMC10148166

Abstract Article PDF–8.0M

Select item 1011200810.

Protein kinase D3 promotes neutrophil migration during viral infection

Janelle M Veazey, Gordon S Wong, Sophia I Eliseeva, Timothy R Smyth, Timothy J Chapman, Kihong Lim, Minsoo Kim, Steve N Georas

Immunol Cell Biol. Author manuscript; available in PMC 2023 Apr 18.

Published in final edited form as: Immunol Cell Biol. 2023 Feb; 101(2): 130–141. Published online 2022 Nov 24. doi: 10.1111/imcb.12603

PMCID:: PMC10112008

Abstract Article PDF–1.4M

Select item 1010285011.

Neutrophil Conversion to a Tumor-Killing Phenotype Underpins Effective Microbial Therapy

Andrew O. Yam, Jacqueline Bailey, Francis Lin, Arnolda Jakovija, Scott E. Youlten, Claudio Counoupas, Matthias Gunzer, Tobias Bald, Trent M. Woodruff, James A. Triccas, Leonard D. Goldstein, David Gallego-Ortega, Shane T. Grey, Tatyana Chtanova

Cancer Res. 2023 Apr 14; 83(8): 1315–1328. Published online 2023 Feb 14. doi: 10.1158/0008-5472.CAN-21-4025

PMCID:: PMC10102850

Abstract Article PDF–20M

Select item 1008021412.

More than neutrophils: Lin(+)Ly6G(+)IL-5Rα(+) multipotent myeloid cells (MMCs) are dominant in normal murine bone marrow and retain capacity to differentiate into eosinophils and monocytes

Brian M. Jeong, Matthew T. Walker, Raul Rodriguez, Mackenzie E. Coden, Reina Nagasaka, Ton C. Doan, Yuliya Politanska, Hiam Abdala-Valencia, Sergejs Berdnikovs

J Leukoc Biol. Author manuscript; available in PMC 2023 Apr 7.

Published in final edited form as: J Leukoc Biol. 2022 Jan; 111(1): 113–122. Published online 2021 Apr 15. doi: 10.1002/JLB.1AB0519-170RR

PMCID:: PMC10080214

Abstract Article PDF–1.7M

Select item 1002252713.

Behavioural immune landscapes of Inflammation

Georgiana Crainiciuc, Miguel Palomino-Segura, Miguel Molina-Moreno, Jon Sicilia, David G. Aragones, Jackson Liang Yao Li, Rodrigo Madurga, José M. Adrover, Alejandra Aroca-Crevillén, Sandra Martin-Salamanca, Alfonso Serrano del Valle, Sandra D. Castillo, Heidi C. E. Welch, Oliver Soehnlein, Mariona Graupera, Fátima Sánchez-Cabo, Alexander Zarbock, Thomas E. Smithgall, Mauro Di Pilato, Thorsten R. Mempel, Pierre-Louis Tharaux, Santiago F. González, Angel Ayuso-Sacido, Lai Guan Ng, Gabriel F. Calvo, Iván González-Díaz, Fernando Díaz-de-María, Andrés Hidalgo

Nature. Author manuscript; available in PMC 2023 Mar 17.

Published in final edited form as: Nature. 2022 Jan; 601(7893): 415–421. Published online 2022 Jan 5. doi: 10.1038/s41586-021-04263-y

PMCID:: PMC10022527

Article PDF–9.8M

Select item 976767614.

Neutrophil “plucking” on megakaryocytes drives platelet production and boosts cardiovascular disease

Tobias Petzold, Zhe Zhang, Iván Ballesteros, Inas Saleh, Amin Polzin, Manuela Thienel, Lulu Liu, Qurrat Ul Ain, Vincent Ehreiser, Christian Weber, Badr Kilani, Pontus Mertsch, Jeremias Götschke, Sophie Cremer, Wenwen Fu, Michael Lorenz, Hellen Ishikawa-Ankerhold, Elisabeth Raatz, Shaza El-Nemr, Agnes Görlach, Esther Marhuenda, Konstantin Stark, Joachim Pircher, David Stegner, Christian Gieger, Marc Schmidt-Supprian, Florian Gaertner, Isaac Almendros, Malte Kelm, Christian Schulz, Andrés Hidalgo, Steffen Massberg

Immunity. 2022 Dec 13; 55(12): 2285–2299.e7. doi: 10.1016/j.immuni.2022.10.001

PMCID:: PMC9767676

Abstract Article

Select item 966316615.

Annexin A2/TLR2/MYD88 pathway induces arginase 1 expression in tumor-associated neutrophils

Huajia Zhang, Xiaodong Zhu, Travis J. Friesen, Jeff W. Kwak, Tatyana Pisarenko, Surapat Mekvanich, Mark A. Velasco, Timothy W. Randolph, Julia Kargl, A. McGarry Houghton

J Clin Invest. 2022 Nov 15; 132(22): e153643. Published online 2022 Nov 15. doi: 10.1172/JCI153643

PMCID:: PMC9663166

Abstract Article PDF–20M

Select item 952724416.

The alarmin interleukin-1α triggers secondary degeneration through reactive astrocytes and endothelium after spinal cord injury

Floriane Bretheau, Adrian Castellanos-Molina, Dominic Bélanger, Maxime Kusik, Benoit Mailhot, Ana Boisvert, Nicolas Vallières, Martine Lessard, Matthias Gunzer, Xiaoyu Liu, Éric Boilard, Ning Quan, Steve Lacroix

Nat Commun. 2022; 13: 5786. Published online 2022 Oct 2. doi: 10.1038/s41467-022-33463-x

PMCID:: PMC9527244

Abstract Article PDF–2.7M

Select item 951275717.

The changing landscape of immune cells in the fetal mouse testis

Samira Hosseini, Sarah C. Moody, Daniela Fietz, Sivanjah Indumathy, Hans-Christian Schuppe, Mark P. Hedger, Kate L. Loveland

Histochem Cell Biol. 2022; 158(4): 345–368. Published online 2022 Jul 12. doi: 10.1007/s00418-022-02129-6

PMCID:: PMC9512757

Abstract Article PDF–16M

Select item 941034118.

Neutrophils incite and macrophages avert electrical storm after myocardial infarction

Jana Grune, Andrew J. M. Lewis, Masahiro Yamazoe, Maarten Hulsmans, David Rohde, Ling Xiao, Shuang Zhang, Christiane Ott, David M. Calcagno, Yirong Zhou, Kerstin Timm, Mayooran Shanmuganathan, Fadi E. Pulous, Maximilian J. Schloss, Brody H. Foy, Diane Capen, Claudio Vinegoni, Gregory R. Wojtkiewicz, Yoshiko Iwamoto, Tilman Grune, Dennis Brown, John Higgins, Vanessa M. Ferreira, Neil Herring, Keith M. Channon, Stefan Neubauer, Oxford Acute Myocardial Infarction (OxAMI) Study, David E. Sosnovik, David J. Milan, Filip K. Swirski, Kevin R. King, Aaron D. Aguirre, Patrick T. Ellinor, Matthias Nahrendorf

Nat Cardiovasc Res. Author manuscript; available in PMC 2022 Aug 25.

Published in final edited form as: Nat Cardiovasc Res. 2022 Jul; 1(7): 649–664. Published online 2022 Jul 11. doi: 10.1038/s44161-022-00094-w

PMCID:: PMC9410341

Abstract Article PDF–6.9M

Select item 920750019.

Neutrophil-Specific Knockdown of β2 Integrins Impairs Antifungal Effector Functions and Aggravates the Course of Invasive Pulmonal Aspergillosis

Maximilian Haist, Frederic Ries, Matthias Gunzer, Monika Bednarczyk, Ekkehard Siegel, Michael Kuske, Stephan Grabbe, Markus Radsak, Matthias Bros, Daniel Teschner

Front Immunol. 2022; 13: 823121. Published online 2022 Jun 6. doi: 10.3389/fimmu.2022.823121

PMCID:: PMC9207500

Abstract Article PDF–2.0M

Select item 904395820.

EpCAM Is Essential to Maintaining the Immune Homeostasis of Intestines via Keeping the Expression of pIgR in the Intestinal Epithelium of Mice

Zili Lei, Wanwan Liu, Ya Nie, Yanhong Yang, Guibin Chen, Li Huang, Huijuan Wu, Yuting Lei, Lei Chen, Qing Hu, Hedong Rong, Siping Yu, Qi Song, Fengxue Tong, Jiao Guo

Front Immunol. 2022; 13: 843378. Published online 2022 Apr 13. doi: 10.3389/fimmu.2022.843378

PMCID:: PMC9043958

Abstract Article PDF–8.1M

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