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Items: 1 to 20 of 89

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Identification of Oxidative Stress and Toll-like Receptor 4 Signaling as a Key Pathway of Acute Lung Injury
Yumiko Imai, Keiji Kuba, G. Greg Neely, Rubina Yaghubian-Malhami, Thomas Perkmann, Geert van Loo, Maria Ermolaeva, Ruud Veldhuizen, Y.H. Connie Leung, Hongliang Wang, Haolin Liu, Yang Sun, Manolis Pasparakis, Manfred Kopf, Christin Mech, Sina Bavari, J.S. Malik Peiris, Arthur S. Slutsky, Shizuo Akira, Malin Hultqvist, Rikard Holmdahl, John Nicholls, Chengyu Jiang, Christoph J. Binder, Josef M. Penninger
Cell. 2008 Apr 18; 133(2): 235–249. Published online 2008 Apr 17. doi: 10.1016/j.cell.2008.02.043
PMCID:
PMC7112336
AbstractArticlePDF–2.9M
3.
Regulating Bcl2L12 expression in mast cells inhibits food allergy
Peng-Yuan Zheng, Xiao-Rui Geng, Jing-Yi Hong, Gui Yang, Jiang-Qi Liu, Li-Hua Mo, Yan Feng, Yuan-Yi Zhang, Tao Liu, Pixin Ran, Zhi-Gang Liu, Ping-Chang Yang
Theranostics. 2019; 9(17): 4982–4992. Published online 2019 Jul 9. doi: 10.7150/thno.34001
PMCID:
PMC6691383
AbstractArticlePDF–1.9M
4.
Activation of the Innate Signaling Molecule MAVS by Bunyavirus Infection Upregulates the Adaptor Protein SARM1, Leading to Neuronal Death
Piyali Mukherjee, Tyson A. Woods, Roger A. Moore, Karin E. Peterson
Immunity. Author manuscript; available in PMC 2016 Mar 8.
Published in final edited form as: Immunity. 2013 Apr 18; 38(4): 705–716. Published online 2013 Mar 14. doi: 10.1016/j.immuni.2013.02.013
PMCID:
PMC4783152
AbstractArticlePDF–1.5M
5.
Interferon-Regulatory Factor 5-Dependent Signaling Restricts Orthobunyavirus Dissemination to the Central Nervous System
Jose Luiz Proenca-Modena, Jennifer L. Hyde, Renata Sesti-Costa, Tiffany Lucas, Amelia K. Pinto, Justin M. Richner, Matthew J. Gorman, Helen M. Lazear, Michael S. Diamond
J Virol. 2016 Jan 1; 90(1): 189–205. Prepublished online 2015 Oct 14. Published online 2015 Dec 17. doi: 10.1128/JVI.02276-15
PMCID:
PMC4702527
AbstractArticlePDF–6.2M
6.
TLR9 and STING agonists synergistically induce innate and adaptive type-II IFN
Burcu Temizoz, Etsushi Kuroda, Keiichi Ohata, Nao Jounai, Koji Ozasa, Kouji Kobiyama, Taiki Aoshi, Ken J Ishii
Eur J Immunol. 2015 Apr; 45(4): 1159–1169. Published online 2015 Feb 5. doi: 10.1002/eji.201445132
PMCID:
PMC4671267
AbstractArticlePDF–893K
7.
Effective and lesion-free cutaneous influenza vaccination
Ji Wang, Bo Li, Mei X. Wu
Proc Natl Acad Sci U S A. 2015 Apr 21; 112(16): 5005–5010. Published online 2015 Apr 6. doi: 10.1073/pnas.1500408112
PMCID:
PMC4413338
AbstractArticlePDF–1.1M
8.
Suppression of systemic autoimmunity by the innate immune adaptor STING
Shruti Sharma, Allison M. Campbell, Jennie Chan, Stefan A. Schattgen, Gregory M. Orlowski, Ribhu Nayar, Annie H. Huyler, Kerstin Nündel, Chandra Mohan, Leslie J. Berg, Mark J. Shlomchik, Ann Marshak-Rothstein, Katherine A. Fitzgerald
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): E710–E717. Published online 2015 Feb 2. doi: 10.1073/pnas.1420217112
PMCID:
PMC4343138
AbstractArticlePDF–1.2M
9.
Positive feedback regulation of type I interferon by the interferon-stimulated gene STING
Feng Ma, Bing Li, Yongxin Yu, Shankar S Iyer, Mingyu Sun, Genhong Cheng
EMBO Rep. 2015 Feb; 16(2): 202–212. Published online 2015 Jan 8. doi: 10.15252/embr.201439366
PMCID:
PMC4328747
AbstractArticlePDF–1.4M
10.
Innate antiviral host defense attenuates TGF-β function through IRF3-mediated suppression of Smad signaling
Pinglong Xu, Samantha Bailey-Bucktrout, Ying Xi, Daqi Xu, Dan Du, Qian Zhang, Weiwen Xiang, Jianming Liu, Andrew Melton, Dean Sheppard, Harold A. Chapman, Jeffrey A. Bluestone, Rik Derynck
Mol Cell. Author manuscript; available in PMC 2015 Dec 18.
Published in final edited form as: Mol Cell. 2014 Dec 18; 56(6): 723–737. doi: 10.1016/j.molcel.2014.11.027
PMCID:
PMC4273650
AbstractArticlePDF–1.9M
11.
Apoptotic caspases prevent the induction of type I interferons by mitochondrial DNA
Anthony Rongvaux, Ruaidhrí Jackson, Christian C.D. Harman, Tuo Li, A. Phillip West, Marcel R. de Zoete, Youtong Wu, Brian Yordy, Saquib A. Lakhani, Chia-Yi Kuan, Tadatsugu Taniguchi, Gerald S. Shadel, Zhijian J. Chen, Akiko Iwasaki, Richard A. Flavell
Cell. Author manuscript; available in PMC 2015 Dec 18.
Published in final edited form as: Cell. 2014 Dec 18; 159(7): 1563–1577. doi: 10.1016/j.cell.2014.11.037
PMCID:
PMC4272443
AbstractArticlePDF–678K
12.
RAE-1 ligands for the NKG2D receptor are regulated by STING-dependent DNA sensor pathways in lymphoma
Adeline R Lam, Nina Le Bert, Samantha SW Ho, Yu J Shen, Li FM Tang, Gordon M Xiong, John L Croxford, Christine X Koo, Ken J Ishii, Shizuo Akira, David H Raulet, Stephan Gasser
Cancer Res. Author manuscript; available in PMC 2015 Apr 15.
Published in final edited form as: Cancer Res. 2014 Apr 15; 74(8): 2193–2203. Published online 2014 Mar 3. doi: 10.1158/0008-5472.CAN-13-1703
PMCID:
PMC4229084
AbstractArticlePDF–5.2M
13.
Age-Dependent Myeloid Dendritic Cell Responses Mediate Resistance to La Crosse Virus-Induced Neurological Disease
Katherine G. Taylor, Tyson A. Woods, Clayton W. Winkler, Aaron B. Carmody, Karin E. Peterson
J Virol. 2014 Oct; 88(19): 11070–11079. doi: 10.1128/JVI.01866-14
PMCID:
PMC4178824
AbstractArticlePDF–1.8M
14.
Type-I interferon signaling through ISGF3 complex is required for sustained Rip3 activation and necroptosis in macrophages
Scott McComb, Erin Cessford, Norah A. Alturki, Julie Joseph, Bojan Shutinoski, Justyna B. Startek, Ana M. Gamero, Karen L. Mossman, Subash Sad
Proc Natl Acad Sci U S A. 2014 Aug 5; 111(31): E3206–E3213. Published online 2014 Jul 21. doi: 10.1073/pnas.1407068111
PMCID:
PMC4128105
AbstractArticlePDF–1.6M
15.
Host-cell sensors for Plasmodium activate innate immunity against liver-stage infection
Peter Liehl, Vanessa Zuzarte-Luís, Jennie Chan, Thomas Zillinger, Fernanda Baptista, Daniel Carapau, Madlen Konert, Kirsten K Hanson, Céline Carret, Caroline Lassnig, Mathias Müller, Ulrich Kalinke, Mohsan Saeed, Angelo Ferreira Chora, Douglas T Golenbock, Birgit Strobl, Miguel Prudêncio, Luis Pedro Coelho, Stefan H Kappe, Giulio Superti-Furga, Andreas Pichlmair, Ana Margarida Vigário, Charles M Rice, Katherine A Fitzgerald, Winfried Barchet, Maria M Mota
Nat Med. Author manuscript; available in PMC 2014 Jul 15.
Published in final edited form as: Nat Med. 2014 Jan; 20(1): 47–53. Published online 2013 Dec 22. doi: 10.1038/nm.3424
PMCID:
PMC4096771
AbstractArticlePDF–1.5M
16.
IRF7-Dependent Type I Interferon Production Induces Lethal Immune-Mediated Disease in STAT1 Knockout Mice Infected with Lymphocytic Choriomeningitis Virus
Wen Li, Markus J. Hofer, So Ri Jung, Sue-Ling Lim, Iain L. Campbell
J Virol. 2014 Jul; 88(13): 7578–7588. doi: 10.1128/JVI.03117-13
PMCID:
PMC4054449
AbstractArticlePDF–2.9M
17.
Differential ability of surface and endosomal TLRs to induce CD8 T cell responses in vivo
Rajakumar Mandraju, Sean Murray, James Forman, Chandrashekhar Pasare
J Immunol. Author manuscript; available in PMC 2015 May 1.
Published in final edited form as: J Immunol. 2014 May 1; 192(9): 4303–4315. Published online 2014 Mar 31. doi: 10.4049/jimmunol.1302244
PMCID:
PMC4002505
AbstractArticlePDF–1.5M
18.
The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data
Gautier Koscielny, Gagarine Yaikhom, Vivek Iyer, Terrence F. Meehan, Hugh Morgan, Julian Atienza-Herrero, Andrew Blake, Chao-Kung Chen, Richard Easty, Armida Di Fenza, Tanja Fiegel, Mark Grifiths, Alan Horne, Natasha A. Karp, Natalja Kurbatova, Jeremy C. Mason, Peter Matthews, Darren J. Oakley, Asfand Qazi, Jack Regnart, Ahmad Retha, Luis A. Santos, Duncan J. Sneddon, Jonathan Warren, Henrik Westerberg, Robert J. Wilson, David G. Melvin, Damian Smedley, Steve D. M. Brown, Paul Flicek, William C. Skarnes, Ann-Marie Mallon, Helen Parkinson
Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D802–D809. Published online 2013 Nov 3. doi: 10.1093/nar/gkt977
PMCID:
PMC3964955
AbstractArticlePDF–5.7M
19.
Interferon Response Factor 3 is crucial to poly-I:C induced NK cell activity and control of B16 melanoma growth
Tyler C. Moore, Phyllis M. Kumm, Deborah M. Brown, Thomas M. Petro
Cancer Lett. Author manuscript; available in PMC 2015 Apr 28.
Published in final edited form as: Cancer Lett. 2014 Apr 28; 346(1): 122–128. Published online 2013 Dec 22. doi: 10.1016/j.canlet.2013.12.022
PMCID:
PMC3963264
AbstractArticlePDF–1.3M
20.
Blockade of TLR3 protects mice from lethal radiation-induced gastrointestinal syndrome
Naoki Takemura, Takumi Kawasaki, Jun Kunisawa, Shintaro Sato, Aayam Lamichhane, Kouji Kobiyama, Taiki Aoshi, Junichi Ito, Kenji Mizuguchi, Thangaraj Karuppuchamy, Kouta Matsunaga, Shoichiro Miyatake, Nobuko Mori, Tohru Tsujimura, Takashi Satoh, Yutaro Kumagai, Taro Kawai, Daron M. Standley, Ken J. Ishii, Hiroshi Kiyono, Shizuo Akira, Satoshi Uematsu
Nat Commun. 2014 Mar 18; 5: 3492. Published online 2014 Mar 18. doi: 10.1038/ncomms4492
PMCID:
PMC3959210
AbstractArticlePDF–2.9M

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