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Items: 1 to 20 of 31

1.
A comprehensive SARS-CoV-2–human protein–protein interactome reveals COVID-19 pathobiology and potential host therapeutic targets
Yadi Zhou, Yuan Liu, Shagun Gupta, Mauricio I. Paramo, Yuan Hou, Chengsheng Mao, Yuan Luo, Julius Judd, Shayne Wierbowski, Marta Bertolotti, Mriganka Nerkar, Lara Jehi, Nir Drayman, Vlad Nicolaescu, Haley Gula, Savaş Tay, Glenn Randall, Peihui Wang, John T. Lis, Cédric Feschotte, Serpil C. Erzurum, Feixiong Cheng, Haiyuan Yu
Nat Biotechnol. Author manuscript; available in PMC 2023 Jan 20.
Published in final edited form as: Nat Biotechnol. 2023 Jan; 41(1): 128–139. Published online 2022 Oct 10. doi: 10.1038/s41587-022-01474-0
PMCID:
PMC9851973
AbstractArticlePDF–4.0M
2.
Interactions of Severe Acute Respiratory Syndrome Coronavirus 2 Protein E With Cell Junctions and Polarity PSD-95/Dlg/ZO-1-Containing Proteins
Yanlei Zhu, Flavio Alvarez, Nicolas Wolff, Ariel Mechaly, Sébastien Brûlé, Benoit Neitthoffer, Sandrine Etienne-Manneville, Ahmed Haouz, Batiste Boëda, Célia Caillet-Saguy
Front Microbiol. 2022; 13: 829094. Published online 2022 Feb 23. doi: 10.3389/fmicb.2022.829094
PMCID:
PMC8909127
AbstractArticlePDF–3.1M
3.
Host PDZ‐containing proteins targeted by SARS‐CoV‐2
Célia Caillet‐Saguy, Fabien Durbesson, Veronica V. Rezelj, Gergö Gogl, Quang Dinh Tran, Jean‐Claude Twizere, Marco Vignuzzi, Renaud Vincentelli, Nicolas Wolff
FEBS J. 2021 Sep; 288(17): 5148–5162. Published online 2021 May 1. doi: 10.1111/febs.15881
PMCID:
PMC8250131
AbstractArticlePDF–1.4M
4.
E3 ubiquitin ligases LNX1 and LNX2 are major regulators of the presynaptic glycine transporter GlyT2
A. de la Rocha-Muñoz, E. Núñez, E. Arribas-González, B. López-Corcuera, C. Aragón, J. de Juan-Sanz
Sci Rep. 2019; 9: 14944. Published online 2019 Oct 18. doi: 10.1038/s41598-019-51301-x
PMCID:
PMC6802383
AbstractArticlePDF–1.6M
5.
Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations
Robert Fragoza, Jishnu Das, Shayne D. Wierbowski, Jin Liang, Tina N. Tran, Siqi Liang, Juan F. Beltran, Christen A. Rivera-Erick, Kaixiong Ye, Ting-Yi Wang, Li Yao, Matthew Mort, Peter D. Stenson, David N. Cooper, Xiaomu Wei, Alon Keinan, John C. Schimenti, Andrew G. Clark, Haiyuan Yu
Nat Commun. 2019; 10: 4141. Published online 2019 Sep 12. doi: 10.1038/s41467-019-11959-3
PMCID:
PMC6742646
AbstractArticlePDF–1.2M
6.
An interactome perturbation framework prioritizes damaging missense mutations for developmental disorders
Siwei Chen, Robert Fragoza, Lambertus Klei, Yuan Liu, Jiebiao Wang, Kathryn Roeder, Bernie Devlin, Haiyuan Yu
Nat Genet. Author manuscript; available in PMC 2019 Jul 1.
Published in final edited form as: Nat Genet. 2018 Jul; 50(7): 1032–1040. Published online 2018 Jun 11. doi: 10.1038/s41588-018-0130-z
PMCID:
PMC6314957
AbstractArticlePDF–1.3M
7.
A protein-protein interaction map of the TNF-induced NF-κB signal transduction pathway
Emmy Van Quickelberghe, Delphine De Sutter, Geert van Loo, Sven Eyckerman, Kris Gevaert
Sci Data. 2018; 5: 180289. Published online 2018 Dec 18. doi: 10.1038/sdata.2018.289
PMCID:
PMC6298254
AbstractArticlePDF–1.4M
8.
VIRMA mediates preferential m6A mRNA methylation in 3′UTR and near stop codon and associates with alternative polyadenylation
Yanan Yue, Jun Liu, Xiaolong Cui, Jie Cao, Guanzheng Luo, Zezhou Zhang, Tao Cheng, Minsong Gao, Xiao Shu, Honghui Ma, Fengqin Wang, Xinxia Wang, Bin Shen, Yizhen Wang, Xinhua Feng, Chuan He, Jianzhao Liu
Cell Discov. 2018; 4: 10. Published online 2018 Feb 27. doi: 10.1038/s41421-018-0019-0
PMCID:
PMC5826926
AbstractArticlePDF–2.3M
9.
Proteomic analysis reveals novel ligands and substrates for LNX1 E3 ubiquitin ligase
Joan A. Lenihan, Orthis Saha, Paul W. Young
PLoS One. 2017; 12(11): e0187352. Published online 2017 Nov 9. doi: 10.1371/journal.pone.0187352
PMCID:
PMC5679597
AbstractArticlePDF–10M
10.
RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination
Nila Roy Choudhury, Gregory Heikel, Maryia Trubitsyna, Peter Kubik, Jakub Stanislaw Nowak, Shaun Webb, Sander Granneman, Christos Spanos, Juri Rappsilber, Alfredo Castello, Gracjan Michlewski
BMC Biol. 2017; 15: 105. Published online 2017 Nov 8. doi: 10.1186/s12915-017-0444-9
PMCID:
PMC5678581
AbstractArticlePDF–3.2M
11.
Systematic interactome mapping of acute lymphoblastic leukemia cancer gene products reveals EXT-1 tumor suppressor as a Notch1 and FBWX7 common interactor
Sarah Daakour, Leon Juvenal Hajingabo, Despoina Kerselidou, Aurelie Devresse, Richard Kettmann, Nicolas Simonis, Franck Dequiedt, Jean-Claude Twizere
BMC Cancer. 2016; 16: 335. Published online 2016 May 26. doi: 10.1186/s12885-016-2374-2
PMCID:
PMC4882867
AbstractArticlePDF–1.8M
12.
Pooled‐matrix protein interaction screens using Barcode Fusion Genetics
Nozomu Yachie, Evangelia Petsalaki, Joseph C Mellor, Jochen Weile, Yves Jacob, Marta Verby, Sedide B Ozturk, Siyang Li, Atina G Cote, Roberto Mosca, Jennifer J Knapp, Minjeong Ko, Analyn Yu, Marinella Gebbia, Nidhi Sahni, Song Yi, Tanya Tyagi, Dayag Sheykhkarimli, Jonathan F Roth, Cassandra Wong, Louai Musa, Jamie Snider, Yi‐Chun Liu, Haiyuan Yu, Pascal Braun, Igor Stagljar, Tong Hao, Michael A Calderwood, Laurence Pelletier, Patrick Aloy, David E Hill, Marc Vidal, Frederick P Roth
Mol Syst Biol. 2016 Apr; 12(4): 863. Published online 2016 Apr 23. doi: 10.15252/msb.20156660
PMCID:
PMC4848762
AbstractArticlePDF–2.8M
13.
Structural basis for the indispensable role of a unique zinc finger motif in LNX2 ubiquitination
Digant Nayak, J. Sivaraman
Oncotarget. 2015 Oct 27; 6(33): 34342–34357. Published online 2015 Oct 5. doi: 10.18632/oncotarget.5326
PMCID:
PMC4741457
AbstractArticlePDF–5.5M
14.
Genetic amplification of the NOTCH modulator LNX2 upregulates the WNT/β-catenin pathway in colorectal cancer
Jordi Camps, Jason J. Pitt, Georg Emons, Amanda B. Hummon, Chanelle M. Case, Marian Grade, Tamara L. Jones, Quang T. Nguyen, B. Michael Ghadimi, Tim Beissbarth, Michael J. Difilippantonio, Natasha J. Caplen, Thomas Ried
Cancer Res. Author manuscript; available in PMC 2016 Jan 27.
Published in final edited form as: Cancer Res. 2013 Mar 15; 73(6): 2003–2013. Published online 2013 Jan 14. doi: 10.1158/0008-5472.CAN-12-3159
PMCID:
PMC4729305
AbstractArticlePDF–1.7M
15.
Quantifying domain-ligand affinities and specificities by high-throughput holdup assay
Renaud Vincentelli, Katja Luck, Juline Poirson, Jolanta Polanowska, Julie Abdat, Marilyne Blémont, Jeremy Turchetto, François Iv, Kevin Ricquier, Marie-Laure Straub, Anne Forster, Patricia Cassonnet, Jean-Paul Borg, Yves Jacob, Murielle Masson, Yves Nominé, Jérôme Reboul, Nicolas Wolff, Sebastian Charbonnier, Gilles Travé
Nat Methods. Author manuscript; available in PMC 2016 Feb 1.
Published in final edited form as: Nat Methods. 2015 Aug; 12(8): 787–793. Published online 2015 Jun 8. doi: 10.1038/nmeth.3438
PMCID:
PMC4521981
AbstractArticlePDF–1.3M
16.
Phospho-tyrosine dependent protein–protein interaction network
Arndt Grossmann, Nouhad Benlasfer, Petra Birth, Anna Hegele, Franziska Wachsmuth, Luise Apelt, Ulrich Stelzl
Mol Syst Biol. 2015 Mar; 11(3): 0794. Published online 2015 Mar 26. doi: 10.15252/msb.20145968
PMCID:
PMC4380928
AbstractArticlePDF–1.9M
17.
A proteome-scale map of the human interactome network
Thomas Rolland, Murat Taşan, Benoit Charloteaux, Samuel J. Pevzner, Quan Zhong, Nidhi Sahni, Song Yi, Irma Lemmens, Celia Fontanillo, Roberto Mosca, Atanas Kamburov, Susan D. Ghiassian, Xinping Yang, Lila Ghamsari, Dawit Balcha, Bridget E. Begg, Pascal Braun, Marc Brehme, Martin P. Broly, Anne-Ruxandra Carvunis, Dan Convery-Zupan, Roser Corominas, Jasmin Coulombe-Huntington, Elizabeth Dann, Matija Dreze, Amélie Dricot, Changyu Fan, Eric Franzosa, Fana Gebreab, Bryan J. Gutierrez, Madeleine F. Hardy, Mike Jin, Shuli Kang, Ruth Kiros, Guan Ning Lin, Katja Luck, Andrew MacWilliams, Jörg Menche, Ryan R. Murray, Alexandre Palagi, Matthew M. Poulin, Xavier Rambout, John Rasla, Patrick Reichert, Viviana Romero, Elien Ruyssinck, Julie M. Sahalie, Annemarie Scholz, Akash A. Shah, Amitabh Sharma, Yun Shen, Kerstin Spirohn, Stanley Tam, Alexander O. Tejeda, Shelly A. Wanamaker, Jean-Claude Twizere, Kerwin Vega, Jennifer Walsh, Michael E. Cusick, Yu Xia, Albert-László Barabási, Lilia M. Iakoucheva, Patrick Aloy, Javier De Las Rivas, Jan Tavernier, Michael A. Calderwood, David E. Hill, Tong Hao, Frederick P. Roth, Marc Vidal
Cell. Author manuscript; available in PMC 2015 Nov 20.
Published in final edited form as: Cell. 2014 Nov 20; 159(5): 1212–1226. doi: 10.1016/j.cell.2014.10.050
PMCID:
PMC4266588
AbstractArticlePDF–3.1M
18.
Discovery of genetic biomarkers contributing to variation in drug response of cytidine analogues using human lymphoblastoid cell lines
Liang Li, Brooke L Fridley, Krishna Kalari, Nifang Niu, Gregory Jenkins, Anthony Batzler, Ryan P Abo, Daniel Schaid, Liewei Wang
BMC Genomics. 2014; 15: 93. Published online 2014 Feb 1. doi: 10.1186/1471-2164-15-93
PMCID:
PMC3930546
AbstractArticlePDF–2.0M
19.
EVI1 oncoprotein interacts with a large and complex network of proteins and integrates signals through protein phosphorylation
Emilie A. Bard-Chapeau, Jayantha Gunaratne, Pankaj Kumar, Belinda Q. Chua, Julius Muller, Frederic A. Bard, Walter Blackstock, Neal G. Copeland, Nancy A. Jenkins
Proc Natl Acad Sci U S A. 2013 Jul 30; 110(31): E2885–E2894. Published online 2013 Jul 15. doi: 10.1073/pnas.1309310110
PMCID:
PMC3732971
AbstractArticlePDF–1.9M
20.
Direct and Indirect Control of Mitogen-activated Protein Kinase Pathway-associated Components, BRAP/IMP E3 Ubiquitin Ligase and CRAF/RAF1 Kinase, by the Deubiquitylating Enzyme USP15
Sebastian D. Hayes, Han Liu, Ewan MacDonald, Christopher M. Sanderson, Judy M. Coulson, Michael J. Clague, Sylvie Urbé
J Biol Chem. 2012 Dec 14; 287(51): 43007–43018. Published online 2012 Oct 26. doi: 10.1074/jbc.M112.386938
PMCID:
PMC3522295
AbstractArticlePDF–2.6M

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