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Select item 114982251.

Acute contact with profibrotic macrophages mechanically activates fibroblasts via αvβ3 integrin–mediated engagement of Piezo1

Maya Ezzo, Katrin Spindler, Jun Bo Wang, Dahea Lee, Gilbert Pecoraro, Justin Cowen, Pardis Pakshir, Boris Hinz

Sci Adv. 2024 Oct 25; 10(43): eadp4726. Published online 2024 Oct 23. doi: 10.1126/sciadv.adp4726

PMCID:: PMC11498225

Abstract Article PDF–16M

Select item 113390322.

Role of TSP-1 and its receptor ITGB3 in the renal tubulointerstitial injury of focal segmental glomerulosclerosis

Yun Fan, Shihui Dong, Yuanyuan Xia, Xue Yang, Qunjuan Lei, Feng Xu, Dandan Liang, Shaoshan Liang, Mingchao Zhang, Fan Yang, Yan Jing, Lijuan Li, Xiaodong Zhu, Hao Bao, Zhaohong Chen, Caihong Zeng

J Biol Chem. 2024 Aug; 300(8): 107516. Published online 2024 Jul 1. doi: 10.1016/j.jbc.2024.107516

PMCID:: PMC11339032

Abstract Article PDF–6.6M

Select item 112172763.

PEX3 promotes regenerative repair after myocardial injury in mice through facilitating plasma membrane localization of ITGB3

Jia-Teng Sun, Zi-Mu Wang, Liu-Hua Zhou, Tong-Tong Yang, Di Zhao, Yu-Lin Bao, Si-Bo Wang, Ling-Feng Gu, Jia-Wen Chen, Tian-Kai Shan, Tian-Wen Wei, Hao Wang, Qi-Ming Wang, Xiang-Qing Kong, Li-Ping Xie, Ai-Hua Gu, Yang Zhao, Feng Chen, Yong Ji, Yi-Qiang Cui, Lian-Sheng Wang

Commun Biol. 2024; 7: 795. Published online 2024 Jul 1. doi: 10.1038/s42003-024-06483-0

PMCID:: PMC11217276

Abstract Article PDF–13M

Select item 109521464.

Integrin β3 regulates apical dendritic morphology of pyramidal neurons throughout hippocampal CA3

Christopher J. Handwerk, Collin J. Denzler, Anna R. Kalinowski, Hollyn N. Cook, Hilda V. Rodriguez, Katherine M. Bland, Cooper A. Brett, Brian D. Swinehart, Elizabeth C. Vinson, George S. Vidal

Hippocampus. 2023 Aug; 33(8): 936–947. Published online 2023 Mar 26. doi: 10.1002/hipo.23530

PMCID:: PMC10952146

Abstract Article PDF–3.0M

Select item 108146885.

Role of Formyl Peptide Receptors and β-Arrestin-1 in suPAR Signal Transduction in Mouse Podocytes: Interactions with αVβ3-Integrin

Eun Young Kim, Stuart E. Dryer

Cells. 2024 Jan; 13(2): 172. Published online 2024 Jan 17. doi: 10.3390/cells13020172

PMCID:: PMC10814688

Abstract Article PDF–3.6M

Select item 107872486.

CD61 identifies a superior population of aged murine HSCs and is required to preserve quiescence and self-renewal

Natalia Skinder, Irene Sanz Fernández, Albertien Dethmers-Ausema, Ellen Weersing, Gerald de Haan

Blood Adv. 2024 Jan 9; 8(1): 99–111. Published online 2023 Nov 10. doi: 10.1182/bloodadvances.2023011585

PMCID:: PMC10787248

Abstract Article PDF–2.0M

Select item 104101377.

Matrix stiffness controls megakaryocyte adhesion, fibronectin fibrillogenesis, and proplatelet formation through Itgβ3

Ines Guinard, Thao Nguyen, Noémie Brassard-Jollive, Josiane Weber, Laurie Ruch, Laura Reininger, Nathalie Brouard, Anita Eckly, Dominique Collin, François Lanza, Catherine Léon

Blood Adv. 2023 Aug 8; 7(15): 4003–4018. Published online 2023 May 15. doi: 10.1182/bloodadvances.2022008680

PMCID:: PMC10410137

Abstract Article PDF–7.2M

Select item 102515418.

Regulation of dendritic spine length in corticopontine layer V pyramidal neurons by autism risk gene β3 integrin

Lucia Celora, Fanny Jaudon, Carmela Vitale, Lorenzo A. Cingolani

Mol Brain. 2023; 16: 49. Published online 2023 Jun 9. doi: 10.1186/s13041-023-01031-z

PMCID:: PMC10251541

Abstract Article PDF–1.8M

Select item 100525359.

Integrin β3-Mediated Cell Senescence Associates with Gut Inflammation and Intestinal Degeneration in Models of Alzheimer’s Disease

Xin Tun, Evan J. Wang, Zhenxiang Gao, Kathleen Lundberg, Rong Xu, Di Hu

Int J Mol Sci. 2023 Mar; 24(6): 5697. Published online 2023 Mar 16. doi: 10.3390/ijms24065697

PMCID:: PMC10052535

Abstract Article PDF–5.7M

Select item 986081810.

SHIP1 Controls Internal Platelet Contraction and α_IIbβ₃ Integrin Dynamics in Early Platelet Activation

Sonia Severin, Alessandra Consonni, Gaëtan Chicanne, Sophie Allart, Bernard Payrastre, Marie-Pierre Gratacap

Int J Mol Sci. 2023 Jan; 24(2): 958. Published online 2023 Jan 4. doi: 10.3390/ijms24020958

PMCID:: PMC9860818

Abstract Article PDF–2.6M

Select item 923616111.

Examining the lineage autonomous role of β3‐integrin in muscle regeneration

Nathalie Gerassimov, Colt Crain, Colin Bilyeu, Andrew Jacob, Chen‐Ming Fan

FASEB J. 2022 Jul; 36(7): e22385. Published online 2022 Jun 23. doi: 10.1096/fj.202200464

PMCID:: PMC9236161

Abstract Article PDF–20M

Select item 921034812.

Periostin Activation of Integrin Receptors on Sensory Neurons Induces Allergic Itch

Santosh K. Mishra, Joshua J. Wheeler, Saumitra Pitake, Huiping Ding, Changyu Jiang, Tomoki Fukuyama, Judy S. Paps, Patrick Ralph, Jacob Coyne, Michelle Parkington, Jennifer DeBrecht, Lauren C. Ehrhardt-Humbert, Glenn P. Cruse, Wolfgang Bäumer, Ru-Rong Ji, Mei-Chuan Ko, Thierry Olivry

Cell Rep. Author manuscript; available in PMC 2022 Jun 21.

Published in final edited form as: Cell Rep. 2020 Apr 7; 31(1): 107472. doi: 10.1016/j.celrep.2020.03.036

PMCID:: PMC9210348

Abstract Article PDF–1.6M

Select item 897209313.

A novel role for endoplasmic reticulum protein 46 (ERp46) in platelet function and arterial thrombosis in mice

Junsong Zhou, Yi Wu, Lubica Rauova, Gavin Koma, Lu Wang, Mortimer Poncz, Hong Li, Tong Liu, Karen P. Fong, Joel S. Bennett, Satya P. Kunapuli, David W. Essex

Blood. 2022 Mar 31; 139(13): 2050–2065. doi: 10.1182/blood.2021012055

PMCID:: PMC8972093

Abstract Article

Select item 889786614.

Integrin β3 in forebrain Emx1-expressing cells regulates repetitive self-grooming and sociability in mice

Andrew J. Lopuch, Brian D. Swinehart, Eden L. Widener, Z. Logan Holley, Katherine M. Bland, Christopher J. Handwerk, Cooper A. Brett, Hollyn N. Cook, Anna R. Kalinowski, Hilda V. Rodriguez, M. Irene Song, George S. Vidal

BMC Neurosci. 2022; 23: 12. Published online 2022 Mar 5. doi: 10.1186/s12868-022-00691-2

PMCID:: PMC8897866

Abstract Article PDF–1.4M

Select item 888491115.

JAGGED1/NOTCH3 activation promotes aortic hypermuscularization and stenosis in elastin deficiency

Jui M. Dave, Raja Chakraborty, Aglaia Ntokou, Junichi Saito, Fatima Z. Saddouk, Zhonghui Feng, Ashish Misra, George Tellides, Robert K. Riemer, Zsolt Urban, Caroline Kinnear, James Ellis, Seema Mital, Robert Mecham, Kathleen A. Martin, Daniel M. Greif

J Clin Invest. 2022 Mar 1; 132(5): e142338. Published online 2022 Mar 1. doi: 10.1172/JCI142338

PMCID:: PMC8884911

Abstract Article PDF–3.3M

Select item 880631416.

Integrin β3 overexpression contributes to podocyte injury through inhibiting RhoA/YAP signaling pathway

Zhuo Li, Zhiwen Lian, Jianchao Ma, Li Zhang, Xingji Lian, Shuangxin Liu, Jianteng Xie, Zhonglin Feng, Ting Lin, Hong Zhang, Xinling Liang

Bioengineered. 2021; 12(1): 1138–1149. Published online 2021 Apr 5. doi: 10.1080/21655979.2021.1906097

PMCID:: PMC8806314

Abstract Article PDF–5.6M

Select item 878017117.

αVβ3 Integrin Expression Is Essential for Replication of Mosquito and Tick-Borne Flaviviruses in Murine Fibroblast Cells

Vinicius Pinho dos Reis, Markus Keller, Katja Schmidt, Rainer Günter Ulrich, Martin Hermann Groschup

Viruses. 2022 Jan; 14(1): 18. Published online 2021 Dec 23. doi: 10.3390/v14010018

PMCID:: PMC8780171

Abstract Article PDF–2.7M

Select item 859481818.

Serotonin transporter-mediated molecular axis regulates regional retinal ganglion cell vulnerability and axon regeneration after nerve injury

Rody Kingston, Dwarkesh Amin, Sneha Misra, Jeffrey M. Gross, Takaaki Kuwajima

PLoS Genet. 2021 Nov; 17(11): e1009885. Published online 2021 Nov 4. doi: 10.1371/journal.pgen.1009885

PMCID:: PMC8594818

Abstract Article PDF–4.6M

Select item 831323919.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 815824920.

Calcium ion chelation preserves platelet function during cold storage

Binggang Xiang, Guoying Zhang, Yan Zhang, Congqing Wu, Smita Joshi, Andrew J. Morris, Jerry Ware, Susan S. Smyth, Sidney W. Whiteheart, Zhenyu Li

Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2022 Jan 1.

Published in final edited form as: Arterioscler Thromb Vasc Biol. 2021 Jan; 41(1): 234–249. Published online 2020 Nov 12. doi: 10.1161/ATVBAHA.120.314879