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Select item 103817141.

Aligning Cross-Species Interactomes for Studying Complex and Chronic Diseases

Marianna Milano, Pietro Cinaglia, Pietro Hiram Guzzi, Mario Cannataro

Life (Basel) 2023 Jul; 13(7): 1520. Published online 2023 Jul 6. doi: 10.3390/life13071520

PMCID:: PMC10381714

Abstract Article PDF–333K

Select item 102957782.

Targeted Central Nervous System Irradiation with Proton Microbeam Induces Mitochondrial Changes in Caenorhabditis elegans

Ahmad Sleiman, Kévin Lalanne, François Vianna, Yann Perrot, Myriam Richaud, Tanima SenGupta, Mikaël Cardot-Martin, Pascal Pedini, Christophe Picard, Hilde Nilsen, Simon Galas, Christelle Adam-Guillermin

Biology (Basel) 2023 Jun; 12(6): 839. Published online 2023 Jun 9. doi: 10.3390/biology12060839

PMCID:: PMC10295778

Abstract Article PDF–2.0M

Select item 98494023.

A new AMPK isoform mediates glucose-restriction induced longevity non-cell autonomously by promoting membrane fluidity

Jin-Hyuck Jeong, Jun-Seok Han, Youngae Jung, Seung-Min Lee, So-Hyun Park, Mooncheol Park, Min-Gi Shin, Nami Kim, Mi Sun Kang, Seokho Kim, Kwang-Pyo Lee, Ki-Sun Kwon, Chun-A. Kim, Yong Ryoul Yang, Geum-Sook Hwang, Eun-Soo Kwon

Nat Commun. 2023; 14: 288. Published online 2023 Jan 18. doi: 10.1038/s41467-023-35952-z

PMCID:: PMC9849402

Abstract Article PDF–2.5M

Select item 95368384.

Independent regulation of mitochondrial DNA quantity and quality in Caenorhabditis elegans primordial germ cells

Aaron ZA Schwartz, Nikita Tsyba, Yusuff Abdu, Maulik R Patel, Jeremy Nance

eLife. 2022; 11: e80396. Published online 2022 Oct 6. doi: 10.7554/eLife.80396

Correction in:: eLife. 2023; 12: e93941.

PMCID:: PMC9536838

Abstract Article PDF–3.7M

Select item 88299885.

Mutant C. elegans mitofusin leads to selective removal of mtDNA heteroplasmic deletions across generations to maintain fitness

Lana Meshnik, Dan Bar-Yaacov, Dana Kasztan, Tali Neiger, Tal Cohen, Mor Kishner, Itay Valenci, Sara Dadon, Christopher J. Klein, Jeffery M. Vance, Yoram Nevo, Stephan Züchner, Ofer Ovadia, Dan Mishmar, Anat Ben-Zvi

BMC Biol. 2022; 20: 40. Published online 2022 Feb 9. doi: 10.1186/s12915-022-01241-2

PMCID:: PMC8829988

Abstract Article PDF–1.9M

Select item 80179866.

The conserved autoimmune-disease risk gene TMEM39A regulates lysosome dynamics

Shuo Luo, Xin Wang, Meirong Bai, Wei Jiang, Zhe Zhang, Yifan Chen, Dengke K. Ma

Proc Natl Acad Sci U S A. 2021 Feb 9; 118(6): e2011379118. Published online 2021 Feb 2. doi: 10.1073/pnas.2011379118

Correction in:: Proc Natl Acad Sci U S A. 2021 Apr 20; 118(16): e2102857118.

PMCID:: PMC8017986

Abstract Article PDF–2.0M

Select item 80040217.

Molecular Basis of Neuronal Autophagy in Ageing: Insights from Caenorhabditis elegans

Georgios Konstantinidis, Nektarios Tavernarakis

Cells. 2021 Mar; 10(3): 694. Published online 2021 Mar 21. doi: 10.3390/cells10030694

PMCID:: PMC8004021

Abstract Article PDF–1.0M

Select item 79003528.

Conserved nicotine-activated neuroprotective pathways involve mitochondrial stress

J. Brucker Nourse, Jr., Gilad Harshefi, Adi Marom, Abdelrahaman Karmi, Hagit Cohen Ben-Ami, Kim A. Caldwell, Guy A. Caldwell, Millet Treinin

iScience. 2021 Mar 19; 24(3): 102140. Published online 2021 Feb 4. doi: 10.1016/j.isci.2021.102140

PMCID:: PMC7900352

Abstract Article PDF–3.3M

Select item 78161229.

NAD⁺ boosting reduces age-associated amyloidosis and restores mitochondrial homeostasis in muscle

Mario Romani, Vincenzo Sorrentino, Chang-Myung Oh, Hao Li, Tanes Imamura de Lima, Hongbo Zhang, Minho Shong, Johan Auwerx

Cell Rep. 2021 Jan 19; 34(3): 108660. Published online 2021 Jan 19. doi: 10.1016/j.celrep.2020.108660

PMCID:: PMC7816122

Abstract Article

Select item 669362510.

Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer’s disease

Evandro F. Fang, Yujun Hou, Konstantinos Palikaras, Bryan A. Adriaanse, Jesse S. Kerr, Beimeng Yang, Sofie Lautrup, Md Mahdi Hasan-Olive, Domenica Caponio, Xiuli Dan, Paula Rocktäschel, Deborah L. Croteau, Mansour Akbari, Nigel H. Greig, Tormod Fladby, Hilde Nilsen, M. Zameel Cader, Mark P. Mattson, Nektarios Tavernarakis, Vilhelm A. Bohr

Nat Neurosci. Author manuscript; available in PMC 2019 Sep 1.

Published in final edited form as: Nat Neurosci. 2019 Mar; 22(3): 401–412. Published online 2019 Feb 11. doi: 10.1038/s41593-018-0332-9

PMCID:: PMC6693625

Abstract Article PDF–1.3M

Select item 667689111.

Zn homeostasis in genetic models of Parkinson’s disease in Caenorhabditis elegans

Jessica Baesler, Johannes F. Kopp, Gabriele Pohl, Michael Aschner, Hajo Haase, Tanja Schwerdtle, Julia Bornhorst

J Trace Elem Med Biol. Author manuscript; available in PMC 2019 Sep 1.

Published in final edited form as: J Trace Elem Med Biol. 2019 Sep; 55: 44–49. Published online 2019 May 29. doi: 10.1016/j.jtemb.2019.05.005

PMCID:: PMC6676891

Abstract Article PDF–540K

Select item 665146112.

Genetic Defects in Mitochondrial Dynamics in Caenorhabditis elegans Impact Ultraviolet C Radiation- and 6-hydroxydopamine-Induced Neurodegeneration

Jessica H. Hartman, Claudia Gonzalez-Hunt, Samantha M. Hall, Ian T. Ryde, Kim A. Caldwell, Guy A. Caldwell, Joel N. Meyer

Int J Mol Sci. 2019 Jul; 20(13): 3202. Published online 2019 Jun 29. doi: 10.3390/ijms20133202

PMCID:: PMC6651461

Abstract Article PDF–5.0M

Select item 621659013.

OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes

Woojin Kim, Ryan S. Underwood, Iva Greenwald, Daniel D. Shaye

Genetics. 2018 Oct; 210(2): 445–461. Published online 2018 Aug 17. doi: 10.1534/genetics.118.301307

PMCID:: PMC6216590

Abstract Article PDF–1.4M

Select item 579271514.

Autophagy and Longevity

Shuhei Nakamura, Tamotsu Yoshimori

Mol Cells. 2018 Jan 31; 41(1): 65–72. Published online 2018 Jan 23. doi: 10.14348/molcells.2018.2333

PMCID:: PMC5792715

Abstract Article PDF–741K

Select item 570389115.

Activation of the mitochondrial unfolded protein response promotes longevity and dopamine neuron survival in Parkinson’s disease models

Jason F. Cooper, Emily Machiela, Dylan J. Dues, Katie K. Spielbauer, Megan M. Senchuk, Jeremy M. Van Raamsdonk

Sci Rep. 2017; 7: 16441. Published online 2017 Nov 27. doi: 10.1038/s41598-017-16637-2

PMCID:: PMC5703891

Abstract Article PDF–11M

Select item 553574116.

Deficiencies in mitochondrial dynamics sensitize Caenorhabditis elegans to arsenite and other mitochondrial toxicants by reducing mitochondrial adaptability

Anthony L. Luz, Tewodros R. Godebo, Latasha L. Smith, Tess C. Leuthner, Laura L. Maurer, Joel N. Meyer

Toxicology. Author manuscript; available in PMC 2018 Jul 15.

Published in final edited form as: Toxicology. 2017 Jul 15; 387: 81–94. Published online 2017 Jun 8. doi: 10.1016/j.tox.2017.05.018

PMCID:: PMC5535741

Abstract Article PDF–1.1M

Select item 549447417.

Molecular definitions of autophagy and related processes

Lorenzo Galluzzi, Eric H Baehrecke, Andrea Ballabio, Patricia Boya, José Manuel Bravo‐San Pedro, Francesco Cecconi, Augustine M Choi, Charleen T Chu, Patrice Codogno, Maria Isabel Colombo, Ana Maria Cuervo, Jayanta Debnath, Vojo Deretic, Ivan Dikic, Eeva‐Liisa Eskelinen, Gian Maria Fimia, Simone Fulda, David A Gewirtz, Douglas R Green, Malene Hansen, J Wade Harper, Marja Jäättelä, Terje Johansen, Gabor Juhasz, Alec C Kimmelman, Claudine Kraft, Nicholas T Ktistakis, Sharad Kumar, Beth Levine, Carlos Lopez‐Otin, Frank Madeo, Sascha Martens, Jennifer Martinez, Alicia Melendez, Noboru Mizushima, Christian Münz, Leon O Murphy, Josef M Penninger, Mauro Piacentini, Fulvio Reggiori, David C Rubinsztein, Kevin M Ryan, Laura Santambrogio, Luca Scorrano, Anna Katharina Simon, Hans‐Uwe Simon, Anne Simonsen, Nektarios Tavernarakis, Sharon A Tooze, Tamotsu Yoshimori, Junying Yuan, Zhenyu Yue, Qing Zhong, Guido Kroemer

EMBO J. 2017 Jul 3; 36(13): 1811–1836. Published online 2017 Jun 8. doi: 10.15252/embj.201796697