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Select item 108227771.

Proteolytic activation of fatty acid synthase signals pan-stress resolution

Hai Wei, Yi M. Weaver, Chendong Yang, Yuan Zhang, Guoli Hu, Courtney M. Karner, Matthew Sieber, Ralph J. DeBerardinis, Benjamin P. Weaver

Nat Metab. 2024; 6(1): 113–126. Published online 2024 Jan 2. doi: 10.1038/s42255-023-00939-z

PMCID:: PMC10822777

Abstract Article PDF–22M

Select item 102799132.

AdipoR2 recruits protein interactors to promote fatty acid elongation and membrane fluidity

Mario Ruiz, Ranjan Devkota, Delaney Kaper, Hanna Ruhanen, Kiran Busayavalasa, Uroš Radović, Marcus Henricsson, Reijo Käkelä, Jan Borén, Marc Pilon

J Biol Chem. 2023 Jun; 299(6): 104799. Published online 2023 May 8. doi: 10.1016/j.jbc.2023.104799

PMCID:: PMC10279913

Abstract Article PDF–4.1M

Select item 101591683.

Transcriptomics of ivermectin response in Caenorhabditis elegans: Integrating abamectin quantitative trait loci and comparison to the Ivermectin-exposed DA1316 strain

Faruk Dube, Andrea Hinas, Nicolas Delhomme, Magnus Åbrink, Staffan Svärd, Eva Tydén

PLoS One. 2023; 18(5): e0285262. Published online 2023 May 4. doi: 10.1371/journal.pone.0285262

PMCID:: PMC10159168

Abstract Article PDF–1.9M

Select item 99104034.

Early-life starvation alters lipid metabolism in adults to cause developmental pathology in Caenorhabditis elegans

James M Jordan, Amy K Webster, Jingxian Chen, Rojin Chitrakar, L Ryan Baugh

Genetics. 2023 Feb; 223(2): iyac172. Published online 2022 Nov 30. doi: 10.1093/genetics/iyac172

PMCID:: PMC9910403

Abstract Article PDF–6.6M

Select item 98854405.

Intracellular lipid surveillance by small G protein geranylgeranylation

Abigail Watterson, Lexus Tatge, Naureen Wajahat, Sonja L. B. Arneaud, Rene Solano Fonseca, Shaghayegh T. Beheshti, Patrick Metang, Melina Mihelakis, Kielen R. Zuurbier, Chase D. Corley, Ishmael Dehghan, Jeffrey G. McDonald, Peter M. Douglas

Nature. Author manuscript; available in PMC 2023 Jan 30.

Published in final edited form as: Nature. 2022 May; 605(7911): 736–740. Published online 2022 May 18. doi: 10.1038/s41586-022-04729-7

PMCID:: PMC9885440

Abstract Article PDF–4.2M

Select item 97499066.

2-hydroxyisobutyric acid (2-HIBA) modulates ageing and fat deposition in Caenorhabditis elegans

Emily Schifano, Giorgia Conta, Adele Preziosi, Carino Ferrante, Giovanni Batignani, Patrizia Mancini, Alberta Tomassini, Fabio Sciubba, Tullio Scopigno, Daniela Uccelletti, Alfredo Miccheli

Front Mol Biosci. 2022; 9: 986022. Published online 2022 Nov 23. doi: 10.3389/fmolb.2022.986022

PMCID:: PMC9749906

Abstract Article PDF–3.1M

Select item 95083367.

Bacterial diet modulates tamoxifen-induced death via host fatty acid metabolism

Cédric Diot, Aurian P. García-González, Andre F. Vieira, Melissa Walker, Megan Honeywell, Hailey Doyle, Olga Ponomarova, Yomari Rivera, Huimin Na, Hefei Zhang, Michael Lee, Carissa P. Olsen, Albertha J. M. Walhout

Nat Commun. 2022; 13: 5595. Published online 2022 Sep 23. doi: 10.1038/s41467-022-33299-5

PMCID:: PMC9508336

Abstract Article PDF–1.4M

Select item 94378488.

Depletion of endogenously biotinylated carboxylases enhances the sensitivity of TurboID-mediated proximity labeling in Caenorhabditis elegans

Murat Artan, Markus Hartl, Weiqiang Chen, Mario de Bono

J Biol Chem. 2022 Sep; 298(9): 102343. Published online 2022 Aug 3. doi: 10.1016/j.jbc.2022.102343

PMCID:: PMC9437848

Abstract Article PDF–2.0M

Select item 92149729.

Caenorhabditis elegans DAF-16 regulates lifespan and immune responses to Cryptococcus neoformans and Cryptococcus gattii infections

Thitinan Kitisin, Watcharamat Muangkaew, Passanesh Sukphopetch

BMC Microbiol. 2022; 22: 162. Published online 2022 Jun 22. doi: 10.1186/s12866-022-02579-x

PMCID:: PMC9214972

Abstract Article PDF–2.5M

Select item 912776910.

Meta-Analysis of Caenorhabditis elegans Transcriptomics Implicates Hedgehog-Like Signaling in Host-Microbe Interactions

Alejandra Zárate-Potes, Irtiqa Ali, Margarida Ribeiro Camacho, Hayley Brownless, Alexandre Benedetto

Front Microbiol. 2022; 13: 853629. Published online 2022 May 10. doi: 10.3389/fmicb.2022.853629

PMCID:: PMC9127769

Abstract Article PDF–4.6M

Select item 902071611.

A modified TurboID approach identifies tissue-specific centriolar components in C. elegans

Elisabeth Holzer, Cornelia Rumpf-Kienzl, Sebastian Falk, Alexander Dammermann

PLoS Genet. 2022 Apr; 18(4): e1010150. Published online 2022 Apr 20. doi: 10.1371/journal.pgen.1010150

Correction in:: PLoS Genet. 2023 Feb; 19(2): e1010645.

PMCID:: PMC9020716

Abstract Article PDF–2.0M

Select item 844679312.

Interactome analysis of Caenorhabditis elegans synapses by TurboID-based proximity labeling

Murat Artan, Stephen Barratt, Sean M. Flynn, Farida Begum, Mark Skehel, Armel Nicolas, Mario de Bono

J Biol Chem. 2021 Sep; 297(3): 101094. Published online 2021 Aug 18. doi: 10.1016/j.jbc.2021.101094

Correction in:: J Biol Chem. 2022 Jun; 298(6): 102081.

PMCID:: PMC8446793

Abstract Article PDF–1.6M

Select item 843352313.

Stress increases in exopher-mediated neuronal extrusion require lipid biosynthesis, FGF, and EGF RAS/MAPK signaling

Jason F. Cooper, Ryan J. Guasp, Meghan Lee Arnold, Barth D. Grant, Monica Driscoll

Proc Natl Acad Sci U S A. 2021 Sep 7; 118(36): e2101410118. Published online 2021 Sep 2. doi: 10.1073/pnas.2101410118

PMCID:: PMC8433523

Abstract Article PDF–1.4M

Select item 840453014.

Fatty acids impact sarcomere integrity through myristoylation and ER homeostasis

Hongyun Tang, Mingxue Cui, Min Han

Cell Rep. Author manuscript; available in PMC 2021 Aug 30.

Published in final edited form as: Cell Rep. 2021 Aug 17; 36(7): 109539. doi: 10.1016/j.celrep.2021.109539

PMCID:: PMC8404530

Abstract Article PDF–2.2M

Select item 833118315.

Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules

Patricia Giselle Cipriani, Olivia Bay, John Zinno, Michelle Gutwein, Hin Hark Gan, Vinay K Mayya, George Chung, Jia-Xuan Chen, Hala Fahs, Yu Guan, Thomas F Duchaine, Matthias Selbach, Fabio Piano, Kristin C Gunsalus

eLife. 2021; 10: e60833. Published online 2021 Jul 5. doi: 10.7554/eLife.60833

PMCID:: PMC8331183

Abstract Article PDF–8.5M

Select item 799517616.

EPIC: Software Toolkit for Elution Profile-Based Inference of Protein Complexes

Lucas ZhongMing Hu, Florian Goebels, June H. Tan, Eric Wolf, Uros Kuzmanov, Cuihong Wan, Sadhna Phanse, Changjiang Xu, Mike Schertzberg, Andrew G. Fraser, Gary D. Bader, Andrew Emili

Nat Methods. Author manuscript; available in PMC 2021 Mar 26.

Published in final edited form as: Nat Methods. 2019 Aug; 16(8): 737–742. Published online 2019 Jul 15. doi: 10.1038/s41592-019-0461-4