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Items: 1 to 20 of 43

1.
NUP98‐BPTF promotes oncogenic transformation through PIM1 upregulation
Mina Noura, Sakura Tomita, Takahiko Yasuda, Shinobu Tsuzuki, Hitoshi Kiyoi, Fumihiko Hayakawa
Cancer Med. 2024 Jul; 13(13): e7445. Published online 2024 Jun 28. doi: 10.1002/cam4.7445
PMCID:
PMC11212001
AbstractArticlePDF–6.4M
2.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
3.
Quantitative Proteomic Analysis Reveals apoE4-Dependent Phosphorylation of the Actin-Regulating Protein VASP
Zeynep Cakir, Samuel J. Lord, Yuan Zhou, Gwendolyn M. Jang, Benjamin J. Polacco, Manon Eckhardt, David Jimenez-Morales, Billy W. Newton, Adam L. Orr, Jeffrey R. Johnson, Alexandre da Cruz, R. Dyche Mullins, Nevan J. Krogan, Robert W. Mahley, Danielle L. Swaney
Mol Cell Proteomics. 2023 May; 22(5): 100541. Published online 2023 Apr 4. doi: 10.1016/j.mcpro.2023.100541
PMCID:
PMC10196575
AbstractArticlePDF–4.5M
4.
The menin-MLL1 interaction is a molecular dependency in NUP98-rearranged AML
Emily B. Heikamp, Jill A. Henrich, Florian Perner, Eric M. Wong, Charles Hatton, Yanhe Wen, Sonali P. Barwe, Anilkumar Gopalakrishnapillai, Haiming Xu, Hannah J. Uckelmann, Sumiko Takao, Yaniv Kazansky, Yana Pikman, Gerard M. McGeehan, Edward A. Kolb, Alex Kentsis, Scott A. Armstrong
Blood. 2022 Feb 10; 139(6): 894–906. doi: 10.1182/blood.2021012806
PMCID:
PMC8832476
AbstractArticle
5.
TLR2/6 signaling promotes the expansion of premalignant hematopoietic stem and progenitor cells in the NUP98-HOXD13 mouse model of MDS
Darlene A. Monlish, Zev J. Greenberg, Sima T. Bhatt, Kathryn M. Leonard, Molly P. Romine, Qian Dong, Lauren Bendesky, Eric J. Duncavage, Jeffrey A. Magee, Laura G. Schuettpelz
Exp Hematol. Author manuscript; available in PMC 2020 Nov 18.
Published in final edited form as: Exp Hematol. 2020 Aug; 88: 42–55. Published online 2020 Jul 8. doi: 10.1016/j.exphem.2020.07.001
PMCID:
PMC7673652
AbstractArticlePDF–2.1M
6.
Brief Report: Loss of p15Ink4b Accelerates Development of Myeloid Neoplasms in Nup98-HoxD13 Transgenic Mice
Rita Humeniuk, Richard Koller, Juraj Bies, Peter Aplan, Linda Wolff
Stem Cells. Author manuscript; available in PMC 2020 Nov 4.
Published in final edited form as: Stem Cells. 2014 May; 32(5): 1361–1366. doi: 10.1002/stem.1635
PMCID:
PMC7640373
AbstractArticlePDF–1.0M
7.
BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)
Kou Motani, Hidetaka Kosako
J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323
PMCID:
PMC7415991
AbstractArticlePDF–2.0M
8.
Interaction of Sox2 with RNA binding proteins in mouse embryonic stem cells
Samudyata, Paulo P. Amaral, Pär G. Engström, Samuel C. Robson, Michael L. Nielsen, Tony Kouzarides, Gonçalo Castelo-Branco
Exp Cell Res. Author manuscript; available in PMC 2020 Aug 1.
Published in final edited form as: Exp Cell Res. 2019 Aug 1; 381(1): 129–138. Published online 2019 May 9. doi: 10.1016/j.yexcr.2019.05.006
PMCID:
PMC6994247
AbstractArticlePDF–1.6M
9.
RAE1 promotes BMAL1 shuttling and regulates degradation and activity of CLOCK: BMAL1 heterodimer
Xulei Zheng, Xu Zhao, Yingying Zhang, Hao Tan, Bojun Qiu, Tengjiao Ma, Jiarong Zeng, Dachang Tao, Yunqiang Liu, Yilu Lu, Yongxin Ma
Cell Death Dis. 2019 Feb; 10(2): 62. Published online 2019 Jan 25. doi: 10.1038/s41419-019-1346-2
PMCID:
PMC6347605
AbstractArticlePDF–3.9M
10.
NUP98-Fusion Proteins Interact With the NSL and MLL1 Complexes To Drive Leukemogenesis
Haiming Xu, Daria G Valerio, Meghan E Eisold, Amit Sinha, Richard P Koche, Wenhuo Hu, Chun-Wei Chen, S Haihua Chu, Gerard L Brien, Christopher Y. Park, James J. Hsieh, Patricia Ernst, Scott A Armstrong
Cancer Cell. Author manuscript; available in PMC 2017 Dec 12.
Published in final edited form as: Cancer Cell. 2016 Dec 12; 30(6): 863–878. Published online 2016 Nov 23. doi: 10.1016/j.ccell.2016.10.019
PMCID:
PMC5501282
AbstractArticlePDF–1.9M
11.
Non-homologous end joining mediated DNA repair is impaired in the NUP98-HOXD13 mouse model for myelodysplastic syndrome
Abdul Gafoor Puthiyaveetil, Christopher M. Reilly, Timothy S. Pardee, David L. Caudell
Leuk Res. Author manuscript; available in PMC 2016 May 26.
Published in final edited form as: Leuk Res. 2013 Jan; 37(1): 112–116. Published online 2012 Nov 4. doi: 10.1016/j.leukres.2012.10.012
PMCID:
PMC4881388
AbstractArticlePDF–289K
12.
Nuclear pore protein NUP88 activates anaphase-promoting complex to promote aneuploidy
Ryan M. Naylor, Karthik B. Jeganathan, Xiuqi Cao, Jan M. van Deursen
J Clin Invest. 2016 Feb 1; 126(2): 543–559. Published online 2016 Jan 5. doi: 10.1172/JCI82277
PMCID:
PMC4731171
AbstractArticlePDF–4.2M
13.
Lamin B1 protein is required for dendrite development in primary mouse cortical neurons
Caterina Giacomini, Sameehan Mahajani, Roberta Ruffilli, Roberto Marotta, Laura Gasparini
Mol Biol Cell. 2016 Jan 1; 27(1): 35–47. doi: 10.1091/mbc.E15-05-0307
PMCID:
PMC4694760
AbstractArticlePDF–7.2M
14.
PKR inhibits the DNA damage response, and is associated with poor survival in AML and accelerated leukemia in NHD13 mice
Xiaodong Cheng, Michael Byrne, Kevin D. Brown, Marina Y. Konopleva, Steven M. Kornblau, Richard L. Bennett, W. Stratford May
Blood. 2015 Sep 24; 126(13): 1585–1594. Prepublished online 2015 Jul 22. doi: 10.1182/blood-2015-03-635227
PMCID:
PMC4582335
AbstractArticle
15.
Control of a neuronal morphology program by an RNA-binding zinc finger protein, Unkempt
Jernej Murn, Kathi Zarnack, Yawei J. Yang, Omer Durak, Elisabeth A. Murphy, Sihem Cheloufi, Dilenny M. Gonzalez, Marianna Teplova, Tomaž Curk, Johannes Zuber, Dinshaw J. Patel, Jernej Ule, Nicholas M. Luscombe, Li-Huei Tsai, Christopher A. Walsh, Yang Shi
Genes Dev. 2015 Mar 1; 29(5): 501–512. doi: 10.1101/gad.258483.115
PMCID:
PMC4358403
AbstractArticlePDF–1.4M
16.
Molecular Basis for the Anchoring of Proto-Oncoprotein Nup98 to the Cytoplasmic Face of the Nuclear Pore Complex
Tobias T. Stuwe, Lennart Schada von Borzyskowski, Andrew M. Davenport, André Hoelz
J Mol Biol. Author manuscript; available in PMC 2014 Nov 10.
Published in final edited form as: J Mol Biol. 2012 Jun 22; 419(5): 330–346. Published online 2012 Apr 2. doi: 10.1016/j.jmb.2012.03.024
PMCID:
PMC4226653
AbstractArticlePDF–3.3M
17.
Nup50 is required for cell differentiation and exhibits transcription-dependent dynamics
Abigail L. Buchwalter, Yun Liang, Martin W. Hetzer
Mol Biol Cell. 2014 Aug 15; 25(16): 2472–2484. doi: 10.1091/mbc.E14-04-0865
PMCID:
PMC4142618
AbstractArticlePDF–6.1M
18.
DELINEATING THE KEY REGIONS AND FUNCTIONS OF NUP98 CONTRIBUTING TO THE LEUKEMOGENIC ACTIVITY OF NUP98-HOX FUSIONS
Eric Yung, Sanja Sekulovic, Bob Argiropoulos, Courteney K. Lai, Malina Leung, Sarah Vollett, Vicky Chi-Dan Chang, Adrian Wan, Sandy Wong, R. Keith Humphries
Leuk Res. Author manuscript; available in PMC 2014 Jun 26.
Published in final edited form as: Leuk Res. 2011 Apr; 35(4): 545–550. Published online 2010 Dec 3. doi: 10.1016/j.leukres.2010.10.006
PMCID:
PMC4072657
AbstractArticlePDF–957K
19.
The fusion partner specifies the oncogenic potential of NUP98 fusion proteins
Jesslyn Saw, David J. Curtis, Damian J. Hussey, Alexander Dobrovic, Peter D. Aplan, Christopher I. Slape
Leuk Res. Author manuscript; available in PMC 2014 Dec 1.
Published in final edited form as: Leuk Res. 2013 Dec; 37(12): 10.1016/j.leukres.2013.09.013. Published online 2013 Sep 21. doi: 10.1016/j.leukres.2013.09.013
PMCID:
PMC3883578
AbstractArticlePDF–951K
20.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M

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