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Items: 1 to 20 of 70

1.
Human mitochondrial Fis1 links to cell cycle regulators at G2/M transition
Seungmin Lee, Yong-Yea Park, Song-Hee Kim, Oanh T. Kim Nguyen, Young-Suk Yoo, Gordon K. Chan, Xuejun Sun, Hyeseong Cho
Cell Mol Life Sci. 2014 Feb; 71(4): 711–725. Published online 2013 Aug 2. doi: 10.1007/s00018-013-1428-8
PMCID:
PMC11113609
AbstractArticlePDF–1.8M
2.
NOTCH localizes to mitochondria through the TBC1D15-FIS1 interaction and is stabilized via blockade of E3 ligase and CDK8 recruitment to reprogram tumor-initiating cells
Hye Yeon Choi, Yicheng Zhu, Xuyao Zhao, Simran Mehta, Juan Carlos Hernandez, Jae-Jin Lee, Yi Kou, Risa Machida, Mauro Giacca, Giannino Del Sal, Ratna Ray, Hyungjin Eoh, Stanley M. Tahara, Lin Chen, Hidekazu Tsukamoto, Keigo Machida
Exp Mol Med. 2024 Feb; 56(2): 461–477. Published online 2024 Feb 27. doi: 10.1038/s12276-024-01174-6
Correction in:
Exp Mol Med. 2024 Oct; 56(10): 2323.
PMCID:
PMC10907578
AbstractArticlePDF–9.4M
3.
Human Fis1 directly interacts with Drp1 in an evolutionarily conserved manner to promote mitochondrial fission
Kelsey A. Nolden, Megan C. Harwig, R. Blake Hill
J Biol Chem. 2023 Dec; 299(12): 105380. Published online 2023 Oct 20. doi: 10.1016/j.jbc.2023.105380
PMCID:
PMC10694664
AbstractArticlePDF–4.1M
4.
A conserved, noncanonical insert in FIS1 mediates TBC1D15 and DRP1 recruitment for mitochondrial fission
Ugochukwu K. Ihenacho, Rafael Toro, Rana H. Mansour, R. Blake Hill
J Biol Chem. 2023 Nov; 299(11): 105303. Published online 2023 Sep 28. doi: 10.1016/j.jbc.2023.105303
PMCID:
PMC10641528
AbstractArticlePDF–7.7M
5.
PDHA1 hyperacetylation-mediated lactate overproduction promotes sepsis-induced acute kidney injury via Fis1 lactylation
Sheng An, Yi Yao, Hongbin Hu, Junjie Wu, Jiaxin Li, Lulan Li, Jie Wu, Maomao Sun, Zhiya Deng, Yaoyuan Zhang, Shenhai Gong, Qiaobing Huang, Zhongqing Chen, Zhenhua Zeng
Cell Death Dis. 2023 Jul; 14(7): 457. Published online 2023 Jul 21. doi: 10.1038/s41419-023-05952-4
PMCID:
PMC10362039
AbstractArticlePDF–7.7M
6.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
7.
Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity
Martin Golkowski, Andrea Lius, Tanmay Sapre, Ho-Tak Lau, Taylor Moreno, Dustin J. Maly, Shao-En Ong
Mol Cell. Author manuscript; available in PMC 2023 Apr 4.
Published in final edited form as: Mol Cell. 2023 Mar 2; 83(5): 803–818.e8. Published online 2023 Feb 2. doi: 10.1016/j.molcel.2023.01.015
PMCID:
PMC10072906
AbstractArticlePDF–4.2M
8.
Assessment of community efforts to advance network-based prediction of protein–protein interactions
Xu-Wen Wang, Lorenzo Madeddu, Kerstin Spirohn, Leonardo Martini, Adriano Fazzone, Luca Becchetti, Thomas P. Wytock, István A. Kovács, Olivér M. Balogh, Bettina Benczik, Mátyás Pétervári, Bence Ágg, Péter Ferdinandy, Loan Vulliard, Jörg Menche, Stefania Colonnese, Manuela Petti, Gaetano Scarano, Francesca Cuomo, Tong Hao, Florent Laval, Luc Willems, Jean-Claude Twizere, Marc Vidal, Michael A. Calderwood, Enrico Petrillo, Albert-László Barabási, Edwin K. Silverman, Joseph Loscalzo, Paola Velardi, Yang-Yu Liu
Nat Commun. 2023; 14: 1582. Published online 2023 Mar 22. doi: 10.1038/s41467-023-37079-7
PMCID:
PMC10033937
AbstractArticlePDF–1.5M
9.
Structural studies of human fission protein FIS1 reveal a dynamic region important for GTPase DRP1 recruitment and mitochondrial fission
John M. Egner, Kelsey A. Nolden, Megan Cleland Harwig, Ryan P. Bonate, Jaime De Anda, Maxx H. Tessmer, Elizabeth L. Noey, Ugochukwu K. Ihenacho, Ziwen Liu, Francis C. Peterson, Gerard C.L. Wong, Michael E. Widlansky, R. Blake Hill
J Biol Chem. 2022 Dec; 298(12): 102620. Published online 2022 Oct 20. doi: 10.1016/j.jbc.2022.102620
PMCID:
PMC9747602
AbstractArticlePDF–4.1M
10.
The N6-methyladenosine-mediated lncRNA WEE2-AS1 promotes glioblastoma progression by stabilizing RPN2
Boyan Li, Rongrong Zhao, Wei Qiu, Ziwen Pan, Shulin Zhao, Yanhua Qi, Jiawei Qiu, Shouji Zhang, Qindong Guo, Yang Fan, Hao Xu, Ming Li, Gang Li, Hao Xue
Theranostics. 2022; 12(14): 6363–6379. Published online 2022 Aug 29. doi: 10.7150/thno.74600
PMCID:
PMC9475453
AbstractArticlePDF–4.4M
11.
Mid51/Fis1 mitochondrial oligomerization complex drives lysosomal untethering and network dynamics
Yvette C. Wong, Soojin Kim, Jasmine Cisneros, Catherine G. Molakal, Pingping Song, Steven J. Lubbe, Dimitri Krainc
J Cell Biol. 2022 Oct 3; 221(10): e202206140. Published online 2022 Aug 31. doi: 10.1083/jcb.202206140
PMCID:
PMC9437119
AbstractArticlePDF–9.9M
12.
PEX11β and FIS1 cooperate in peroxisome division independently of mitochondrial fission factor
Tina A. Schrader, Ruth E. Carmichael, Markus Islinger, Joseph L. Costello, Christian Hacker, Nina A. Bonekamp, Jochen H. Weishaupt, Peter M. Andersen, Michael Schrader
J Cell Sci. 2022 Jul 1; 135(13): jcs259924. Published online 2022 Jul 8. doi: 10.1242/jcs.259924
PMCID:
PMC9377713
AbstractArticle
13.
Iron chelation promotes mitophagy through SENP3-mediated deSUMOylation of FIS1
Kevin A. Wilkinson, Chun Guo
Autophagy. 2022; 18(7): 1743–1745. Published online 2022 Mar 11. doi: 10.1080/15548627.2022.2046898
PMCID:
PMC9298444
AbstractArticlePDF–357K
14.
Cullin 3 Exon 9 Deletion in Familial Hyperkalemic Hypertension Impairs Cullin3-Ring-E3 Ligase (CRL3) Dynamic Regulation and Cycling
Ilektra Kouranti, Waed Abdel Khalek, Stephani Mazurkiewicz, Irmine Loisel-Ferreira, Alexis M. Gautreau, Lionel Pintard, Xavier Jeunemaitre, Eric Clauser
Int J Mol Sci. 2022 May; 23(9): 5151. Published online 2022 May 5. doi: 10.3390/ijms23095151
PMCID:
PMC9105235
AbstractArticlePDF–5.8M
15.
Fis1 phosphorylation by Met promotes mitochondrial fission and hepatocellular carcinoma metastasis
Yan Yu, Xiao-Dan Peng, Xiao-Jun Qian, Kai-Ming Zhang, Xiang Huang, Yu-Hong Chen, Yun-Tian Li, Gong-Kan Feng, Hai-Liang Zhang, Xue-Lian Xu, Shun Li, Xuan Li, Jia Mai, Zhi-Ling Li, Yun Huang, Dong Yang, Li-Huan Zhou, Zhuo-Yan Zhong, Jun-Dong Li, Rong Deng, Xiao-Feng Zhu
Signal Transduct Target Ther. 2021; 6: 401. Published online 2021 Dec 1. doi: 10.1038/s41392-021-00790-2
PMCID:
PMC8632923
AbstractArticlePDF–7.0M
16.
Protein interaction landscapes revealed by advanced in vivo cross-linking–mass spectrometry
Andrew Wheat, Clinton Yu, Xiaorong Wang, Anthony M. Burke, Ilan E. Chemmama, Robyn M. Kaake, Peter Baker, Scott D. Rychnovsky, Jing Yang, Lan Huang
Proc Natl Acad Sci U S A. 2021 Aug 10; 118(32): e2023360118. Published online 2021 Aug 4. doi: 10.1073/pnas.2023360118
PMCID:
PMC8364181
AbstractArticlePDF–3.0M
17.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
18.
Mitochondrial Fission Protein 1: Emerging Roles in Organellar Form and Function in Health and Disease
Ugochukwu Kelvin Ihenacho, Kelsey A. Meacham, Megan Cleland Harwig, Michael E. Widlansky, R. Blake Hill
Front Endocrinol (Lausanne) 2021; 12: 660095. Published online 2021 Mar 25. doi: 10.3389/fendo.2021.660095
PMCID:
PMC8027123
AbstractArticlePDF–2.0M
19.
Human skeletal muscle mitochondrial dynamics in relation to oxidative capacity and insulin sensitivity
Alexandre Houzelle, Johanna A. Jörgensen, Gert Schaart, Sabine Daemen, Nynke van Polanen, Ciarán E. Fealy, Matthijs K. C. Hesselink, Patrick Schrauwen, Joris Hoeks
Diabetologia. 2021; 64(2): 424–436. Published online 2020 Nov 30. doi: 10.1007/s00125-020-05335-w
PMCID:
PMC7801361
AbstractArticlePDF–2.7M
20.
Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism
Michael Aregger, Keith A. Lawson, Maximillian Billmann, Michael Costanzo, Amy H. Y. Tong, Katherine Chan, Mahfuzur Rahman, Kevin R. Brown, Catherine Ross, Matej Usaj, Lucy Nedyalkova, Olga Sizova, Andrea Habsid, Judy Pawling, Zhen-Yuan Lin, Hala Abdouni, Cassandra J. Wong, Alexander Weiss, Patricia Mero, James W. Dennis, Anne-Claude Gingras, Chad L. Myers, Brenda J. Andrews, Charles Boone, Jason Moffat
Nat Metab. Author manuscript; available in PMC 2020 Dec 1.
Published in final edited form as: Nat Metab. 2020 Jun; 2(6): 499–513. Published online 2020 Jun 1. doi: 10.1038/s42255-020-0211-z
PMCID:
PMC7566881
AbstractArticlePDF–4.8M

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