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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 96635212.

Protein tyrosine kinase 6 regulates activation of SRC kinase

Wanian M. Alwanian, Katarina Vlajic, Wenjun Bie, Andre Kajdacsy-Balla, Angela L. Tyner

J Biol Chem. 2022 Nov; 298(11): 102584. Published online 2022 Oct 10. doi: 10.1016/j.jbc.2022.102584

PMCID:: PMC9663521

Abstract Article PDF–3.9M

Select item 79387703.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 56881484.

PTEN is a protein phosphatase that targets active PTK6 and inhibits PTK6 oncogenic signaling in prostate cancer

Darren J. Wozniak, Andre Kajdacsy-Balla, Virgilia Macias, Susan Ball-Kell, Morgan L. Zenner, Wenjun Bie, Angela L. Tyner

Nat Commun. 2017; 8: 1508. Published online 2017 Nov 15. doi: 10.1038/s41467-017-01574-5

PMCID:: PMC5688148

Abstract Article PDF–5.5M

Select item 48479195.

TNFα/IFNγ Mediated Intestinal Epithelial Barrier Dysfunction Is Attenuated by MicroRNA-93 Downregulation of PTK6 in Mouse Colonic Epithelial Cells

Ricci J. Haines, Richard S. Beard, Jr., Rebecca A. Eitner, Liwei Chen, Mack H. Wu

PLoS One. 2016; 11(4): e0154351. Published online 2016 Apr 27. doi: 10.1371/journal.pone.0154351

PMCID:: PMC4847919

Abstract Article PDF–6.0M

Select item 45679526.

Protein Tyrosine Kinase 6 Regulates UVB Induced Signaling and Tumorigenesis in Mouse Skin

Michael Chastkofsky, Wenjun Bie, Susan M. Ball-Kell, Yu-Ying He, Angela L. Tyner

J Invest Dermatol. Author manuscript; available in PMC 2016 Apr 1.

Published in final edited form as: J Invest Dermatol. 2015 Oct; 135(10): 2492–2501. Published online 2015 Apr 30. doi: 10.1038/jid.2015.166

PMCID:: PMC4567952

Abstract Article PDF–2.2M

Select item 45585037.

Protein tyrosine kinase 6 promotes ERBB2-induced mammary gland tumorigenesis in the mouse

M Peng, S M Ball-Kell, A L Tyner

Cell Death Dis. 2015 Aug; 6(8): e1848. Published online 2015 Aug 6. doi: 10.1038/cddis.2015.210

PMCID:: PMC4558503

Abstract Article PDF–3.2M

Select item 42765288.

Protein tyrosine kinase 6 mediates TNFα-induced endothelial barrier dysfunction

RJ Haines, RS Beard, MH Wu

Biochem Biophys Res Commun. Author manuscript; available in PMC 2016 Jan 2.

Published in final edited form as: Biochem Biophys Res Commun. 2015 Jan 2; 456(1): 190–196. Published online 2014 Nov 22. doi: 10.1016/j.bbrc.2014.11.057

PMCID:: PMC4276528

Abstract Article PDF–2.0M

Select item 39402649.

Protein Tyrosine Kinase 6 Protects Cells from Anoikis by Directly Phosphorylating Focal Adhesion Kinase and Activating AKT

Yu Zheng, Jessica Gierut, Zebin Wang, Jianjun Miao, John M. Asara, Angela L. Tyner

Oncogene. Author manuscript; available in PMC 2014 Mar 5.

Published in final edited form as: Oncogene. 2013 Sep 5; 32(36): 4304–4312. Published online 2012 Oct 1. doi: 10.1038/onc.2012.427

PMCID:: PMC3940264

Abstract Article PDF–1.6M

Select item 357241010.

A conditional knockout resource for the genome–wide study of mouse gene function

William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley

Nature. Author manuscript; available in PMC 2013 Feb 14.

Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163

PMCID:: PMC3572410

Abstract Article PDF–1.1M

Select item 344894411.

Disruption of the Mouse Protein Tyrosine Kinase 6 Gene Prevents STAT3 Activation and Confers Resistance to Azoxymethane

Jessica Gierut, Yu Zheng, Wenjun Bie, Robert E. Carroll, Susan Ball-Kell, Andrea Haegebarth, Angela L. Tyner

Gastroenterology. Author manuscript; available in PMC 2012 Oct 1.

Published in final edited form as: Gastroenterology. 2011 Oct; 141(4): 1371–1380.e2. Published online 2011 Jul 8. doi: 10.1053/j.gastro.2011.06.071

PMCID:: PMC3448944

Abstract Article PDF–3.8M

Select item 326220112.

Mammary gland specific expression of Brk/PTK6 promotes delayed involution and tumor formation associated with activation of p38 MAPK

Kristopher A Lofgren, Julie H Ostrander, Daniel Housa, Gregory K Hubbard, Alessia Locatelli, Robin L Bliss, Kathryn L Schwertfeger, Carol A Lange

Breast Cancer Res. 2011; 13(5): R89. Published online 2011 Sep 17. doi: 10.1186/bcr2946

PMCID:: PMC3262201

Abstract Article PDF–3.4M

Select item 324906613.

Protein-tyrosine Kinase 6 Promotes Peripheral Adhesion Complex Formation and Cell Migration by Phosphorylating p130 CRK-associated Substrate

Yu Zheng, John M. Asara, Angela L. Tyner

J Biol Chem. 2012 Jan 2; 287(1): 148–158. Published online 2011 Nov 14. doi: 10.1074/jbc.M111.298117

PMCID:: PMC3249066

Abstract Article PDF–2.6M

Select item 317805914.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 302253415.

A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo

Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio

PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582

PMCID:: PMC3022534

Abstract Article PDF–3.8M

Select item 300520016.

A Conditionally Immortalized Colonic Epithelial Cell Line From A Ptk6 Null Mouse That Polarizes And Differentiates In Vitro

Robert H. Whitehead, Pamela. S. Robinson, Janice A. Williams, Wenjun Bie, Angela. L. Tyner, Jeffrey L. Franklin

J Gastroenterol Hepatol. Author manuscript; available in PMC 2010 Dec 21.

Published in final edited form as: J Gastroenterol Hepatol. 2008 Jul; 23(7 Pt 1): 1119–1124. Published online 2008 Jan 19. doi: 10.1111/j.1440-1746.2008.05308.x