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Items: 1 to 20 of 65

1.
α-Kleisin subunit of cohesin preserves the genome integrity of embryonic stem cells
Seobin Yoon, Eui-Hwan Choi, Seo Jung Park, Keun Pil Kim
BMB Rep. 2023 Feb 28; 56(2): 108–113. Published online 2023 Feb 1. doi: 10.5483/BMBRep.2022-0106
PMCID:
PMC9978357
AbstractArticlePDF–9.1M
2.
RAD21 amplification epigenetically suppresses interferon signaling to promote immune evasion in ovarian cancer
Peng Deng, Zining Wang, Jinghong Chen, Shini Liu, Xiaosai Yao, Shaoyan Liu, Lizhen Liu, Zhaoliang Yu, Yulin Huang, Zhongtang Xiong, Rong Xiao, Jiuping Gao, Weiting Liang, Jieping Chen, Hui Liu, Jing Han Hong, Jason Yongsheng Chan, Peiyong Guan, Jianfeng Chen, Yali Wang, Jiaxin Yin, Jundong Li, Min Zheng, Chao Zhang, Penghui Zhou, Tiebang Kang, Bin Tean Teh, Qiang Yu, Zhixiang Zuo, Qingping Jiang, Jihong Liu, Ying Xiong, Xiaojun Xia, Jing Tan
J Clin Invest. 2022 Nov 15; 132(22): e159628. Published online 2022 Nov 15. doi: 10.1172/JCI159628
PMCID:
PMC9663158
AbstractArticlePDF–15M
3.
Cohesin couples transcriptional bursting probabilities of inducible enhancers and promoters
Irene Robles-Rebollo, Sergi Cuartero, Adria Canellas-Socias, Sarah Wells, Mohammad M. Karimi, Elisabetta Mereu, Alexandra G. Chivu, Holger Heyn, Chad Whilding, Dirk Dormann, Samuel Marguerat, Inmaculada Rioja, Rab K. Prinjha, Michael P. H. Stumpf, Amanda G. Fisher, Matthias Merkenschlager
Nat Commun. 2022; 13: 4342. Published online 2022 Jul 27. doi: 10.1038/s41467-022-31192-9
PMCID:
PMC9329429
AbstractArticlePDF–4.9M
4.
Cohesin-dependence of neuronal gene expression relates to chromatin loop length
Lesly Calderon, Felix D Weiss, Jonathan A Beagan, Marta S Oliveira, Radina Georgieva, Yi-Fang Wang, Thomas S Carroll, Gopuraja Dharmalingam, Wanfeng Gong, Kyoko Tossell, Vincenzo de Paola, Chad Whilding, Mark A Ungless, Amanda G Fisher, Jennifer E Phillips-Cremins, Matthias Merkenschlager
eLife. 2022; 11: e76539. Published online 2022 Apr 26. doi: 10.7554/eLife.76539
PMCID:
PMC9106336
AbstractArticlePDF–6.3M
5.
Alternative Functions of Cell Cycle-Related and DNA Repair Proteins in Post-mitotic Neurons
Remi Akagawa, Yo-ichi Nabeshima, Takeshi Kawauchi
Front Cell Dev Biol. 2021; 9: 753175. Published online 2021 Oct 20. doi: 10.3389/fcell.2021.753175
PMCID:
PMC8564117
AbstractArticlePDF–2.2M
6.
Clonal selection of stable aneuploidies in progenitor cells drives high-prevalence tumorigenesis
Marianna Trakala, Muskaan Aggarwal, Courtney Sniffen, Lauren Zasadil, Allison Carroll, Duanduan Ma, Xiaofeng A. Su, Darawalee Wangsa, Ashleigh Meyer, Cynthia J. Sieben, Jian Zhong, Pei-hsin Hsu, Glenn Paradis, Thomas Ried, Andrew Holland, Jan Van Deursen, Angelika Amon
Genes Dev. 2021 Aug 1; 35(15-16): 1079–1092. doi: 10.1101/gad.348341.121
PMCID:
PMC8336892
AbstractArticlePDF–6.4M
7.
Neuronal genes deregulated in Cornelia de Lange Syndrome respond to removal and re-expression of cohesin
Felix D. Weiss, Lesly Calderon, Yi-Fang Wang, Radina Georgieva, Ya Guo, Nevena Cvetesic, Maninder Kaur, Gopuraja Dharmalingam, Ian D. Krantz, Boris Lenhard, Amanda G. Fisher, Matthias Merkenschlager
Nat Commun. 2021; 12: 2919. Published online 2021 May 18. doi: 10.1038/s41467-021-23141-9
PMCID:
PMC8131595
AbstractArticlePDF–3.9M
8.
Wapl releases Scc1-cohesin and regulates chromosome structure and segregation in mouse oocytes
Mariana C.C. Silva, Sean Powell, Sabrina Ladstätter, Johanna Gassler, Roman Stocsits, Antonio Tedeschi, Jan-Michael Peters, Kikuë Tachibana
J Cell Biol. 2020 Apr 6; 219(4): e201906100. Published online 2020 Mar 17. doi: 10.1083/jcb.201906100
PMCID:
PMC7147110
AbstractArticlePDF–4.6M
9.
Antisense lncRNA transcription mediates DNA demethylation to drive stochastic Protocadherin α promoter choice
Daniele Canzio, Chiamaka L. Nwakeze, Adan Horta, Sandy M. Rajkumar, Eliot L. Coffey, Erin E. Duffy, Rachel Duffié, Kevin Monahan, Sean o’Keeffe, Matthew D. Simon, Stavros Lomvardas, Tom Maniatis
Cell. Author manuscript; available in PMC 2020 Apr 18.
Published in final edited form as: Cell. 2019 Apr 18; 177(3): 639–653.e15. Published online 2019 Apr 4. doi: 10.1016/j.cell.2019.03.008
PMCID:
PMC6823843
AbstractArticlePDF–2.8M
10.
Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics
Joel D. Federspiel, Todd M. Greco, Krystal K. Lum, Ileana M. Cristea
Mol Cell Proteomics. 2019 Aug 9; 18(8 Suppl 1): S92–S113. Published online 2019 Apr 30. doi: 10.1074/mcp.RA118.001253
PMCID:
PMC6692770
AbstractArticlePDF–7.7M
11.
Control of inducible gene expression links cohesin to hematopoietic progenitor self-renewal and differentiation
Sergi Cuartero, Felix D. Weiss, Gopuraja Dharmalingam, Ya Guo, Elizabeth Ing-Simmons, Silvia Masella, Irene Robles-Rebollo, Xiaolin Xiao, Yi-Fang Wang, Iros Barozzi, Dounia Djeghloul, Mariane T. Amano, Henri Niskanen, Enrico Petretto, Robin D. Dowell, Kikuë Tachibana, Minna U. Kaikkonen, Kim A. Nasmyth, Boris Lenhard, Gioacchino Natoli, Amanda G. Fisher, Matthias Merkenschlager
Nat Immunol. Author manuscript; available in PMC 2019 Feb 20.
Published in final edited form as: Nat Immunol. 2018 Sep; 19(9): 932–941. Published online 2018 Aug 20. doi: 10.1038/s41590-018-0184-1
PMCID:
PMC6195188
AbstractArticlePDF–3.0M
12.
Expression of RAD21 Immunoreactivity in Myenteric Neurons of the Human and Mouse Small Intestine
Francesca Bianco, Seth T. Eisenman, Maria Gabriela Colmenares Aguilar, Elena Bonora, Paolo Clavenzani, David R. Linden, Roberto De Giorgio, Gianrico Farrugia, Simon J. Gibbons
Neurogastroenterol Motil. Author manuscript; available in PMC 2019 Sep 1.
Published in final edited form as: Neurogastroenterol Motil. 2018 Sep; 30(9): e13429. Published online 2018 Aug 1. doi: 10.1111/nmo.13429
PMCID:
PMC6150808
AbstractArticlePDF–1.5M
13.
A mechanism of cohesin‐dependent loop extrusion organizes zygotic genome architecture
Johanna Gassler, Hugo B Brandão, Maxim Imakaev, Ilya M Flyamer, Sabrina Ladstätter, Wendy A Bickmore, Jan‐Michael Peters, Leonid A Mirny, Kikuë Tachibana
EMBO J. 2017 Dec 15; 36(24): 3600–3618. Published online 2017 Dec 7. doi: 10.15252/embj.201798083
PMCID:
PMC5730859
AbstractArticlePDF–3.3M
14.
5C analysis of the Epidermal Differentiation Complex locus reveals distinct chromatin interaction networks between gene-rich and gene-poor TADs in skin epithelial cells
Krzysztof Poterlowicz, Joanne L. Yarker, Igor Malashchuk, Brian R. Lajoie, Andrei N. Mardaryev, Michal R. Gdula, Andrey A. Sharov, Terumi Kohwi-Shigematsu, Vladimir A. Botchkarev, Michael Y. Fessing
PLoS Genet. 2017 Sep; 13(9): e1006966. Published online 2017 Sep 1. doi: 10.1371/journal.pgen.1006966
PMCID:
PMC5599062
AbstractArticlePDF–7.0M
15.
The cohesin subunit Rad21 is a negative regulator of hematopoietic self-renewal through epigenetic repression of HoxA7 and HoxA9
Joseph B. Fisher, Jonathan Peterson, Michael Reimer, Jr., Cary Stelloh, Kirthi Pulakanti, Zachary J. Gerbec, Alex M. Abel, Jennifer Miksanek Strouse, Christopher Strouse, Maureen McNulty, Subramaniam Malarkannan, John D. Crispino, Samuel Milanovich, Sridhar Rao
Leukemia. Author manuscript; available in PMC 2017 Mar 2.
Published in final edited form as: Leukemia. 2017 Mar; 31(3): 712–719. Published online 2016 Aug 24. doi: 10.1038/leu.2016.240
PMCID:
PMC5332284
AbstractArticlePDF–1.5M
16.
A Surveillance Mechanism Ensures Repair of DNA Lesions during Zygotic Reprogramming
Sabrina Ladstätter, Kikuë Tachibana-Konwalski
Cell. 2016 Dec 15; 167(7): 1774–1787.e13. doi: 10.1016/j.cell.2016.11.009
PMCID:
PMC5161750
AbstractArticle
17.
Corticothalamic projection neuron development beyond subtype specification: Fog2 and intersectional controls regulate intra-class neuronal diversity
Maria J. Galazo, Jason G. Emsley, Jeffrey D. Macklis
Neuron. Author manuscript; available in PMC 2017 Jul 6.
Published in final edited form as: Neuron. 2016 Jul 6; 91(1): 90–106. Published online 2016 Jun 16. doi: 10.1016/j.neuron.2016.05.024
PMCID:
PMC5094453
AbstractArticlePDF–1.6M
18.
Conditional mutation of Smc5 in mouse embryonic stem cells perturbs condensin localization and mitotic progression
Marina V. Pryzhkova, Philip W. Jordan
J Cell Sci. 2016 Apr 15; 129(8): 1619–1634. doi: 10.1242/jcs.179036
PMCID:
PMC4852767
AbstractArticle
19.
Pharmacological targeting of the Wdr5-MLL interaction in C/EBPa N-terminal leukemia
Florian Grebien, Masoud Vedadi, Matthäus Getlik, Roberto Giambruno, Amit Grover, Roberto Avellino, Anna Skucha, Sarah Vittori, Ekaterina Kuznetsova, David Smil, Dalia Barsyte-Lovejoy, Fengling Li, Gennadiy Poda, Matthieu Schapira, Hong Wu, Aiping Dong, Guillermo Senisterra, Alexey Stukalov, Kilian V. M. Huber, Andreas Schönegger, Richard Marcellus, Martin Bilban, Christoph Bock, Peter J. Brown, Johannes Zuber, Keiryn L. Bennett, Rima Al-awar, Ruud Delwel, Claus Nerlov, Cheryl H. Arrowsmith, Giulio Superti-Furga
Nat Chem Biol. Author manuscript; available in PMC 2016 Feb 1.
Published in final edited form as: Nat Chem Biol. 2015 Aug; 11(8): 571–578. Published online 2015 Jul 13. doi: 10.1038/nchembio.1859
PMCID:
PMC4511833
AbstractArticlePDF–2.2M
20.
Cohesin-mediated interactions organize chromosomal domain architecture
Sevil Sofueva, Eitan Yaffe, Wen-Ching Chan, Dimitra Georgopoulou, Matteo Vietri Rudan, Hegias Mira-Bontenbal, Steven M Pollard, Gary P Schroth, Amos Tanay, Suzana Hadjur
EMBO J. 2013 Dec 11; 32(24): 3119–3129. Published online 2013 Nov 1. doi: 10.1038/emboj.2013.237
PMCID:
PMC4489921
AbstractArticlePDF–2.1M

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