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Items: 1 to 20 of 142

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Identification of new ciliary signaling pathways in the brain and insights into neurological disorders
Abdelhalim Loukil, Emma Ebright, Akiyoshi Uezu, Yudong Gao, Scott H Soderling, Sarah C. Goetz
Version 1. bioRxiv. Preprint. 2023 Dec 21. doi: 10.1101/2023.12.20.572700
PMCID:
PMC10769350
AbstractArticlePDF–11M
3.
Downregulation of mGluR1-mediated signaling underlying autistic-like core symptoms in Shank1 P1812L-knock-in mice
Yue Qin, Xiao-Yong Zhang, Yanyan Liu, Zehan Ma, Shuo Tao, Ying Li, Rui Peng, Fei Wang, Jiucun Wang, Jianfeng Feng, Zilong Qiu, Li Jin, Hongyan Wang, Xiaohong Gong
Transl Psychiatry. 2023; 13: 329. Published online 2023 Oct 25. doi: 10.1038/s41398-023-02626-9
PMCID:
PMC10600164
AbstractArticlePDF–2.7M
4.
A vital role for PICK1 in the differential regulation of metabotropic glutamate receptor internalization and synaptic AMPA receptor endocytosis
Namrata Ramsakha, Prachi Ojha, Subhajit Pal, Sanjeev Routh, Ami Citri, Samarjit Bhattacharyya
J Biol Chem. 2023 Jun; 299(6): 104837. Published online 2023 May 18. doi: 10.1016/j.jbc.2023.104837
PMCID:
PMC10276164
AbstractArticlePDF–3.8M
5.
Protein Networks Associated with Native Metabotropic Glutamate 1 Receptors (mGlu1) in the Mouse Cerebellum
Mahnaz Mansouri, Leopold Kremser, Thanh-Phuong Nguyen, Yu Kasugai, Laura Caberlotto, Martin Gassmann, Bettina Sarg, Herbert Lindner, Bernhard Bettler, Lucia Carboni, Francesco Ferraguti
Cells. 2023 May; 12(9): 1325. Published online 2023 May 5. doi: 10.3390/cells12091325
PMCID:
PMC10177021
AbstractArticlePDF–2.8M
6.
Glutamate can act as a signaling molecule in mouse preimplantation embryos
Alexandra Špirková, Veronika Kovaříková, Zuzana Šefčíková, Jozef Pisko, Martina Kšiňanová, Juraj Koppel, Dušan Fabian, Štefan Čikoš
Biol Reprod. 2022 Oct; 107(4): 916–927. Published online 2022 Jun 23. doi: 10.1093/biolre/ioac126
PMCID:
PMC9562114
AbstractArticlePDF–1.5M
7.
mGluR5 Is Substitutable for mGluR1 in Cerebellar Purkinje Cells for Motor Coordination, Developmental Synapse Elimination, and Motor Learning
Maria Harbers, Harumi Nakao, Takaki Watanabe, Kyoko Matsuyama, Shoichi Tohyama, Kazuki Nakao, Yasushi Kishimoto, Masanobu Kano, Atsu Aiba
Cells. 2022 Jul; 11(13): 2004. Published online 2022 Jun 23. doi: 10.3390/cells11132004
PMCID:
PMC9265771
AbstractArticlePDF–2.2M
8.
Coordination chemogenetics for activation of GPCR-type glutamate receptors in brain tissue
Kento Ojima, Wataru Kakegawa, Tokiwa Yamasaki, Yuta Miura, Masayuki Itoh, Yukiko Michibata, Ryou Kubota, Tomohiro Doura, Eriko Miura, Hiroshi Nonaka, Seiya Mizuno, Satoru Takahashi, Michisuke Yuzaki, Itaru Hamachi, Shigeki Kiyonaka
Nat Commun. 2022; 13: 3167. Published online 2022 Jun 16. doi: 10.1038/s41467-022-30828-0
PMCID:
PMC9203742
AbstractArticlePDF–5.8M
9.
Stabilization of Spine Synaptopodin by mGluR1 Is Required for mGluR-LTD
Luisa Speranza, Yanis Inglebert, Claudia De Sanctis, Pei You Wu, Magdalena Kalinowska, R. Anne McKinney, Anna Francesconi
J Neurosci. 2022 Mar 2; 42(9): 1666–1678. doi: 10.1523/JNEUROSCI.1466-21.2022
PMCID:
PMC8896548
AbstractArticlePDF–3.0M
10.
Proteasomal degradation of the metabotropic glutamate receptor 1α is mediated by Homer-3 via the proteasomal S8 ATPase
Khosrow Rezvani, Kelli Baalman, Yanfen Teng, Maureen P. Mee, Simon P. Dawson, Hongmin Wang, Mariella De Biasi, R. John Mayer
J Neurochem. Author manuscript; available in PMC 2022 Feb 27.
Published in final edited form as: J Neurochem. 2012 Jul; 122(1): 24–37. Published online 2012 Apr 27. doi: 10.1111/j.1471-4159.2012.07752.x
PMCID:
PMC8882371
AbstractArticlePDF–1.4M
11.
Loss of zinc-finger protein 212 leads to Purkinje cell death and locomotive abnormalities with phospholipase D3 downregulation
Rin Khang, Areum Jo, Hojin Kang, Hanna Kim, Eunsang Kwag, Ji-Yeong Lee, Okjae Koo, Jinsu Park, Hark Kyun Kim, Dong-Gyu Jo, Inwoo Hwang, Jee-Yin Ahn, Yunjong Lee, Jeong-Yun Choi, Yun-Song Lee, Joo-Ho Shin
Sci Rep. 2021; 11: 22745. Published online 2021 Nov 23. doi: 10.1038/s41598-021-02218-x
PMCID:
PMC8610974
AbstractArticlePDF–2.5M
12.
Graded heterogeneity of metabotropic signaling underlies a continuum of cell-intrinsic temporal responses in unipolar brush cells
Chong Guo, Vincent Huson, Evan Z. Macosko, Wade G. Regehr
Nat Commun. 2021; 12: 5491. Published online 2021 Oct 7. doi: 10.1038/s41467-021-22893-8
PMCID:
PMC8497507
AbstractArticlePDF–4.7M
13.
circ-Grm1 promotes pulmonary artery smooth muscle cell proliferation and migration via suppression of GRM1 expression by FUS
Shijing Sun, Qingyu Kong, Zhifeng Cai, Minmin Wang, Haizhao Zhao, Cuifen Zhao
Int J Mol Med. 2021 Nov; 48(5): 202. Published online 2021 Sep 16. doi: 10.3892/ijmm.2021.5035
PMCID:
PMC8480385
AbstractArticlePDF–8.7M
14.
Loss of retinoid X receptor gamma subunit impairs group 1 mGluR mediated electrophysiological responses and group 1 mGluR dependent behaviors
Chirag Upreti, Caitlin M. Woodruff, Xiao-Lei Zhang, Michael J. Yim, Zhen-yu Zhou, Andrew M. Pagano, Dina S. Rehanian, Deqi Yin, Eric R. Kandel, Patric K. Stanton, Russell E. Nicholls
Sci Rep. 2021; 11: 5552. Published online 2021 Mar 10. doi: 10.1038/s41598-021-84943-x
PMCID:
PMC7946894
AbstractArticlePDF–5.1M
15.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
16.
Unipolar (Dendritic) Brush Cells Are Morphologically Complex and Require Tbr2 for Differentiation and Migration
Ashley McDonough, Gina E. Elsen, Ray M. Daza, Amelia R. Bachleda, Donald Pizzo, Olivia M. DelleTorri, Robert F. Hevner
Front Neurosci. 2020; 14: 598548. Published online 2021 Jan 8. doi: 10.3389/fnins.2020.598548
PMCID:
PMC7820753
AbstractArticlePDF–8.2M
17.
Repression of Irs2 by let‐7 miRNAs is essential for homeostasis of the telencephalic neuroepithelium
Virginia Fernández, Maria Ángeles Martínez‐Martínez, Anna Prieto‐Colomina, Adrián Cárdenas, Rafael Soler, Martina Dori, Ugo Tomasello, Yuki Nomura, José P López‐Atalaya, Federico Calegari, Víctor Borrell
EMBO J. 2020 Nov 2; 39(21): e105479. Published online 2020 Sep 28. doi: 10.15252/embj.2020105479
PMCID:
PMC7604626
AbstractArticlePDF–16M
18.
mGlu1 tonically regulates levels of calcium-permeable AMPA receptors in cultured nucleus accumbens neurons through retinoic acid signaling and protein translation
Jessica A. Loweth, Jeremy M. Reimers, Aaron Caccamise, Michael T. Stefanik, Kin-Yan Woo, Nirav M. Chauhan, Craig T. Werner, Marina E. Wolf
Eur J Neurosci. Author manuscript; available in PMC 2020 Oct 14.
Published in final edited form as: Eur J Neurosci. 2019 Aug; 50(3): 2590–2601. Published online 2018 Oct 14. doi: 10.1111/ejn.14151
PMCID:
PMC7556732
AbstractArticlePDF–1.0M
19.
Elevated Type 1 Metabotropic Glutamate Receptor Availability in a Mouse Model of Huntington’s Disease: a Longitudinal PET Study
Daniele Bertoglio, Jeroen Verhaeghe, Špela Korat, Alan Miranda, Klaudia Cybulska, Leonie Wyffels, Sigrid Stroobants, Ladislav Mrzljak, Celia Dominguez, Mette Skinbjerg, Longbin Liu, Ignacio Munoz-Sanjuan, Steven Staelens
Mol Neurobiol. 2020; 57(4): 2038–2047. Published online 2020 Jan 8. doi: 10.1007/s12035-019-01866-5
PMCID:
PMC7118044
AbstractArticlePDF–2.8M
20.
The metabotropic glutamate receptor subtype 1 regulates development and maintenance of lemniscal synaptic connectivity in the somatosensory thalamus
Madoka Narushima, Yuki Yagasaki, Yuichi Takeuchi, Atsu Aiba, Mariko Miyata
PLoS One. 2019; 14(12): e0226820. Published online 2019 Dec 27. doi: 10.1371/journal.pone.0226820
PMCID:
PMC6934304
AbstractArticlePDF–2.5M

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