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Select item 111494151.

ANGPTL3 negatively regulates IL-1β-induced NF-κB activation by inhibiting the IL1R1-associated signaling complex assembly

Yu Zhang, Zi-tong Zhang, Shi-yuan Wan, Jing Yang, Yu-juan Wei, Hui-jing Chen, Wan-zhu Zhou, Qiu-yi Song, Shu-xuan Niu, Ling Zheng, Kun Huang

J Mol Cell Biol. 2023 Aug; 15(8): mjad053. Published online 2023 Aug 26. doi: 10.1093/jmcb/mjad053

PMCID:: PMC11149415

Abstract Article PDF–2.2M

Select item 110410152.

IL-1 receptor 1 signaling shapes the development of viral antigen-specific CD4⁺ T cell responses following COVID-19 mRNA vaccination

Hong-Jai Park, Min Sun Shin, Junghee J. Shin, Hyoungsu Kim, Byunghyun Kang, Jennefer Par-Young, Serhan Unlu, Yuliya Afinogenova, Jason Catanzaro, Juan Young, Minhyung Kim, Sang Jin Lee, Sangchoon Jeon, Sungyong You, Michael K. Racke, Richard Bucala, Insoo Kang

eBioMedicine. 2024 May; 103: 105114. Published online 2024 Apr 18. doi: 10.1016/j.ebiom.2024.105114

PMCID:: PMC11041015

Abstract Article PDF–1.8M

Select item 106453953.

A paracrine circuit of IL-1β/IL-1R1 between myeloid and tumor cells drives genotype-dependent glioblastoma progression

Zhihong Chen, Bruno Giotti, Milota Kaluzova, Montse Puigdelloses Vallcorba, Kavita Rawat, Gabrielle Price, Cameron J. Herting, Gonzalo Pinero, Simona Cristea, James L. Ross, James Ackley, Victor Maximov, Frank Szulzewsky, Wes Thomason, Mar Marquez-Ropero, Angelo Angione, Noah Nichols, Nadejda M. Tsankova, Franziska Michor, Dmitry M. Shayakhmetov, David H. Gutmann, Alexander M. Tsankov, Dolores Hambardzumyan

J Clin Invest. 2023 Nov 15; 133(22): e163802. Published online 2023 Nov 15. doi: 10.1172/JCI163802

PMCID:: PMC10645395

Abstract Article PDF–13M

Select item 104994824.

Genotype Frequencies of 50 Polymorphisms for 241 Japanese Non-cancer Patients

Nobuyuki Hamajima, Toshiko Saito, Keitaro Matsuo, Takashi Suzuki, Tsuneya Nakamura, Akio Matsuura, Katashi Okuma, Kazuo Tajima

J Epidemiol. 2002; 12(3): 229–236. Published online 2007 Nov 30. doi: 10.2188/jea.12.229

PMCID:: PMC10499482

Abstract Article PDF–588K

Select item 101923775.

The role of genetic polymorphisms of interleukin-1 (IL-1R1 and IL-1RN) in primary knee osteoarthritis in Indonesia

Nicolaas C. Budhiparama, Imelda Lumban-Gaol, Herawati Sudoyo, Rahadyan Magetsari, Tri Wibawa

Sci Rep. 2023; 13: 7967. Published online 2023 May 17. doi: 10.1038/s41598-023-34824-2

PMCID:: PMC10192377

Abstract Article PDF–1.0M

Select item 93916066.

Expression-based Genome-wide Association Study Links OPN and IL1-RA With Newly Diagnosed Type 1 Diabetes in Children

Xiaofan Jia, Kyoko Toda, Ling He, Dongmei Miao, Satoru Yamada, Liping Yu, Keiichi Kodama

J Clin Endocrinol Metab. 2022 Jul; 107(7): 1825–1832. Published online 2022 Apr 23. doi: 10.1210/clinem/dgac256

PMCID:: PMC9391606

Abstract Article

Select item 86473777.

The association of genetic polymorphisms in interleukin-1 receptors type 1 and type 2 with sudden sensorineural hearing loss in a Taiwanese population: a case control study

Chen-Yu Chien, Shu-Yu Tai, Kuan-Hui Li, Hua-Ling Yang, Leong-Perng Chan, Edward Hsi, Ling-Feng Wang, Kuen-Yao Ho, Ning-Chia Chang

J Otolaryngol Head Neck Surg. 2021; 50: 69. Published online 2021 Dec 5. doi: 10.1186/s40463-021-00550-w

PMCID:: PMC8647377

Abstract Article PDF–846K

Select item 81650308.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 81057259.

MyD88 oligomer size functions as a physical threshold to trigger IL1R Myddosome signaling

Rafael Deliz-Aguirre, Fakun Cao, Fenja H.U. Gerpott, Nichanok Auevechanichkul, Mariam Chupanova, YeVin Mun, Elke Ziska, Marcus J. Taylor

J Cell Biol. 2021 Jul 5; 220(7): e202012071. Published online 2021 May 6. doi: 10.1083/jcb.202012071

PMCID:: PMC8105725

Abstract Article PDF–8.7M

Select item 747873510.

Neuronal interleukin-1 receptors mediate pain in chronic inflammatory diseases

Benoit Mailhot, Marine Christin, Nicolas Tessandier, Chaudy Sotoudeh, Floriane Bretheau, Roxanne Turmel, Ève Pellerin, Feng Wang, Cyril Bories, Charles Joly-Beauparlant, Yves De Koninck, Arnaud Droit, Francesca Cicchetti, Grégory Scherrer, Eric Boilard, Reza Sharif-Naeini, Steve Lacroix

J Exp Med. 2020 Sep 7; 217(9): e20191430. Published online 2020 Jun 23. doi: 10.1084/jem.20191430

PMCID:: PMC7478735

Abstract Article PDF–5.3M

Select item 741971311.

Increased Expression of Interleukin-1 Receptor Characterizes Anti-estrogen-Resistant ALDH⁺ Breast Cancer Stem Cells

Aida Sarmiento-Castro, Eva Caamaño-Gutiérrez, Andrew H. Sims, Nathan J. Hull, Mark I. James, Angélica Santiago-Gómez, Rachel Eyre, Christopher Clark, Martha E. Brown, Michael D. Brooks, Max S. Wicha, Sacha J. Howell, Robert B. Clarke, Bruno M. Simões

Stem Cell Reports. 2020 Aug 11; 15(2): 307–316. Published online 2020 Jul 23. doi: 10.1016/j.stemcr.2020.06.020

PMCID:: PMC7419713

Abstract Article PDF–2.1M

Select item 741819112.

The IL1β-IL1R signaling is involved in the stimulatory effects triggered by hypoxia in breast cancer cells and cancer-associated fibroblasts (CAFs)

Rosamaria Lappano, Marianna Talia, Francesca Cirillo, Damiano Cosimo Rigiracciolo, Domenica Scordamaglia, Rita Guzzi, Anna Maria Miglietta, Ernestina Marianna De Francesco, Antonino Belfiore, Andrew H. Sims, Marcello Maggiolini

J Exp Clin Cancer Res. 2020; 39: 153. Published online 2020 Aug 10. doi: 10.1186/s13046-020-01667-y

PMCID:: PMC7418191

Abstract Article PDF–3.4M

Select item 738998913.

IL1R1基因多态性与儿童哮喘的相关性

刘燕, 刘晟, 吴宏辉, 张翔

Zhongguo Dang Dai Er Ke Za Zhi. 2016 Mar 15; 18(3): 243–246. Chinese. doi: 10.7499/j.issn.1008-8830.2016.03.011

PMCID:: PMC7389989

Abstract Article PDF–1.1M

Select item 713751114.

The association of genetic polymorphisms in interleukin-1 receptors type 1 and type 2 with age-related hearing impairment in a Taiwanese population: a case control study

Ning-Chia Chang, Hua-Ling Yang, Chia-Yen Dai, Wen-Yi Lin, Hsun-Mo Wang, Chen-Yu Chien, Kuen-Yao Ho

J Otolaryngol Head Neck Surg. 2020; 49: 16. Published online 2020 Apr 6. doi: 10.1186/s40463-020-00410-z

PMCID:: PMC7137511

Abstract Article PDF–501K

Select item 654062015.

IL1R1 Polymorphisms are Associated with Lumbar Disc Herniation Risk in the Northwestern Chinese Han Population

Yong Zhu, Shunan Li, Yao Sun, Jiamin Wu, Zichao Xiong, Tianbo Jin, Haiyu Jia, Xuejun Yang

Med Sci Monit. 2019; 25: 3728–3738. Published online 2019 May 19. doi: 10.12659/MSM.913563

PMCID:: PMC6540620

Abstract Article PDF–1.3M

Select item 641837516.

Impact of IL1R1 and IL1R2 gene polymorphisms on risk of osteonecrosis of the femoral head from a case–control study

Feimeng An, Jiaqi Wang, Hongyan Gao, Chang Liu, Ye Tian, Tianbo Jin, Wanlin Liu, Jianzhong Wang

Mol Genet Genomic Med. 2019 Mar; 7(3): e00557. Published online 2019 Jan 8. doi: 10.1002/mgg3.557

PMCID:: PMC6418375

Abstract Article PDF–422K

Select item 639202717.

A Critical Role of the IL-1β-IL-1R Signaling Pathway in Skin Inflammation and Psoriasis Pathogenesis

Yihua Cai, Feng Xue, Chen Quan, Minye Qu, Na Liu, Yuan Zhang, Chris Fleming, Xiaoling Hu, Huang-ge Zhang, Ralph Weichselbaum, Yang-xin Fu, David Tieri, Eric C. Rouchka, Jie Zheng, Jun Yan

J Invest Dermatol. Author manuscript; available in PMC 2020 Jan 1.

Published in final edited form as: J Invest Dermatol. 2019 Jan; 139(1): 146–156. Published online 2018 Aug 16. doi: 10.1016/j.jid.2018.07.025

PMCID:: PMC6392027

Abstract Article PDF–1.2M

Select item 616668218.

Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei

Domenico Fasci, Hugo van Ingen, Richard A. Scheltema, Albert J. R. Heck

Mol Cell Proteomics. 2018 Oct; 17(10): 2018–2033. Published online 2018 Jul 18. doi: 10.1074/mcp.RA118.000924

PMCID:: PMC6166682

Abstract Article PDF–3.8M

Select item 608539319.

T cell-intrinsic IL-1R signaling licenses effector cytokine production by memory CD4 T cells

Aakanksha Jain, Ran Song, Edward K. Wakeland, Chandrashekhar Pasare

Nat Commun. 2018; 9: 3185. Published online 2018 Aug 9. doi: 10.1038/s41467-018-05489-7

PMCID:: PMC6085393

Abstract Article PDF–1.3M

Select item 601963920.

Sputum cell interleukin-1 receptor expression level is a marker of airway neutrophilia and airflow obstruction in asthma

Michael D. Evans, Stephane Esnault, Loren C. Denlinger, Nizar N. Jarjour

J Allergy Clin Immunol. Author manuscript; available in PMC 2019 Aug 1.

Published in final edited form as: J Allergy Clin Immunol. 2018 Aug; 142(2): 415–423. Published online 2017 Dec 26. doi: 10.1016/j.jaci.2017.09.035

PMCID:: PMC6019639

Abstract Article PDF–1.5M

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