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Select item 109249201.

ADAMTS4 is a crucial proteolytic enzyme for versican cleavage in the amnion at parturition

Meng-Die Li, Jiang-Wen Lu, Fan Zhang, Wen-Jia Lei, Fan Pan, Yi-Kai Lin, Li-Jun Ling, Leslie Myatt, Wang-Sheng Wang, Kang Sun

Commun Biol. 2024; 7: 301. Published online 2024 Mar 9. doi: 10.1038/s42003-024-06007-w

PMCID:: PMC10924920

Abstract Article PDF–8.3M

Select item 105287032.

ADAMTS proteoglycanases downregulation with impaired oocyte quality in PCOS

Sepide Gohari taban, Iraj Amiri, Massoud Saidijam, Sara Soleimani asl, Mahnaz Yavangi, Elham Khanlarzadeh, Nooshin Mohammadpour, Tayebe Artimani

Arch Endocrinol Metab. 2021 Jan-Feb; 65(1): 60–66. Published online 2021 Jan 14. doi: 10.20945/2359-3997000000321

PMCID:: PMC10528703

Abstract Article PDF–238K

Select item 102089573.

ADAMTS4 is involved in the production of the Alzheimer disease amyloid biomarker APP669-711

Masaya Matsuzaki, Miyabishara Yokoyama, Yota Yoshizawa, Naoki Kaneko, Hiroki Naito, Honoka Kobayashi, Akihito Korenaga, Sadanori Sekiya, Kentaro Ikemura, Gabriel Opoku, Satoshi Hirohata, Shinichi Iwamoto, Koichi Tanaka, Taisuke Tomita

Mol Psychiatry. 2023; 28(4): 1802–1812. Published online 2023 Feb 1. doi: 10.1038/s41380-023-01946-y

PMCID:: PMC10208957

Abstract Article PDF–3.2M

Select item 91978554.

Identification of Adamts4 as a novel adult cardiac injury biomarker with therapeutic implications in patients with cardiac injuries

Riffat Khanam, Arunima Sengupta, Dipankar Mukhopadhyay, Santanu Chakraborty

Sci Rep. 2022; 12: 9898. Published online 2022 Jun 14. doi: 10.1038/s41598-022-13918-3

PMCID:: PMC9197855

Abstract Article PDF–10M

Select item 81650305.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 78836276.

Exuberant fibroblast activity compromises lung function via ADAMTS-4

David F. Boyd, E. Kaitlynn Allen, Adrienne G. Randolph, Xi-zhi J. Guo, Yunceng Weng, Catherine J. Sanders, Resha Bajracharya, Natalie K. Lee, Clifford S. Guy, Peter Vogel, Wenda Guan, Yimin Li, Xiaoqing Liu, Tanya Novak, Margaret M. Newhams, Thomas P. Fabrizio, Nicholas Wohlgemuth, Peter M. Mourani, PALISI Pediatric Intensive Care Influenza (PICFLU) Investigators, Thomas N. Wight, Stacey Schultz-Cherry, Stephania A. Cormier, Kathryn Shaw-Saliba, Andrew Pekosz, Richard E. Rothman, Kuan-Fu Chen, Zifeng Yang, Richard J. Webby, Nanshan Zhong, Jeremy Chase Crawford, Paul G. Thomas

Nature. Author manuscript; available in PMC 2021 May 1.

Published in final edited form as: Nature. 2020 Nov; 587(7834): 466–471. Published online 2020 Oct 28. doi: 10.1038/s41586-020-2877-5

PMCID:: PMC7883627

Abstract Article PDF–5.5M

Select item 77586467.

Interrelationship of Osteopontin, MMP-9 and ADAMTS4 in Patients With Osteoarthritis Undergoing Total Joint Arthroplasty

Hannah Slovacek, Rajan Khanna, Pavel Poredos, Mateja Jezovnik, Debra Hoppensteadt, Jawed Fareed, William Hopkinson

Clin Appl Thromb Hemost. 2020 Jan-Dec; 26: 1076029620964864. Published online 2020 Dec 22. doi: 10.1177/1076029620964864

PMCID:: PMC7758646

Abstract Article PDF–369K

Select item 74912678.

The utility of synovial fluid levels of ADAMTS9 and ADAMTS4 in predicting treatment responses to intraarticular steroid injections in patients with knee osteoarthritis

Kenan ÖZLER

Turk J Med Sci. 2020; 50(5): 1330–1336. Published online 2020 Aug 26. doi: 10.3906/sag-1809-108

PMCID:: PMC7491267

Abstract Article PDF–196K

Select item 70501039.

AMPK Interactome Reveals New Function in Non-homologous End Joining DNA Repair

Zhen Chen, Chao Wang, Antrix Jain, Mrinal Srivastava, Mengfan Tang, Huimin Zhang, Xu Feng, Litong Nie, Dan Su, Yun Xiong, Sung Yun Jung, Jun Qin, Junjie Chen

Mol Cell Proteomics. 2020 Mar; 19(3): 467–477. Published online 2020 Jan 3. doi: 10.1074/mcp.RA119.001794

PMCID:: PMC7050103

Abstract Article PDF–1.8M

Select item 691202010.

Single‐nucleotide polymorphisms in the coding region of a disintegrin and metalloproteinase with thrombospondin motifs 4 and hepatocellular carcinoma: A retrospective case‐control study

Xing‐Zhizi Wang, Wei‐Zhong Tang, Qun‐Ying Su, Jin‐Guang Yao, Xiao‐Ying Huang, Qin‐Qin Long, Xue‐Min Wu, Qiang Xia, Xi‐Dai Long

Cancer Med. 2019 Dec; 8(18): 7869–7880. Published online 2019 Oct 30. doi: 10.1002/cam4.2646

PMCID:: PMC6912020

Abstract Article PDF–568K

Select item 626562211.

Association of ADAMTS4 and ADAMTS5 polymorphisms with musculoskeletal degenerative diseases: a systematic review and meta-analysis

Jian-Zhong Huo, Xing-Hua Ji, Zhong-Yi Su, Peng Shang, Fei Gao

Biosci Rep. 2018 Dec 21; 38(6): BSR20181619. Prepublished online 2018 Oct 28. Published online 2018 Nov 30. doi: 10.1042/BSR20181619

PMCID:: PMC6265622

Abstract Article PDF–987K

Select item 561788712.

Critical Role of ADAMTS-4 in the Development of Sporadic Aortic Aneurysm and Dissection in Mice

Pingping Ren, Michael Hughes, Swapna Krishnamoorthy, Sili Zou, Lin Zhang, Darrell Wu, Chen Zhang, John A. Curci, Joseph S. Coselli, Dianna M. Milewicz, Scott A. LeMaire, Ying H. Shen

Sci Rep. 2017; 7: 12351. Published online 2017 Sep 27. doi: 10.1038/s41598-017-12248-z

PMCID:: PMC5617887

Abstract Article PDF–3.9M

Select item 553161113.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 544332514.

Versican Proteolysis by ADAMTS Proteases and Its Influence on Sex Steroid Receptor Expression in Uterine Leiomyoma

Ndeye-Aicha Gueye, Timothy J. Mead, Christopher D. Koch, Charles V. Biscotti, Tommaso Falcone, Suneel S. Apte

J Clin Endocrinol Metab. 2017 May 1; 102(5): 1631–1641. Published online 2017 Feb 6. doi: 10.1210/jc.2016-3527

PMCID:: PMC5443325

Abstract Article

Select item 535513215.

Cleavage of Fibulin-2 by the aggrecanases ADAMTS-4 and ADAMTS-5 contributes to the tumorigenic potential of breast cancer cells

Tania Fontanil, Saúl Álvarez-Teijeiro, M. Ángeles Villaronga, Yamina Mohamedi, Laura Solares, Angela Moncada-Pazos, José A. Vega, Olivia García-Suárez, Marcos Pérez-Basterrechea, Juana M. García-Pedrero, Alvaro J Obaya, Santiago Cal

Oncotarget. 2017 Feb 21; 8(8): 13716–13729. Published online 2017 Jan 11. doi: 10.18632/oncotarget.14627

PMCID:: PMC5355132

Abstract Article PDF–10M

Select item 533696916.

A novel association between TGFβl and ADAMTS4 in coronary artery disease: A new potential mechanism in the progression of atherosclerosis and diabetes

Safiye Uluçay, Fethi Sırrı Çam, Muhammed Burak Batır, Recep Sütçü, Özgür Bayturan, Kadir Demircan

Anatol J Cardiol. 2015 Oct; 15(10): 823–829. Published online 2014 Oct 31. doi: 10.5152/akd.2014.5762

PMCID:: PMC5336969

Abstract Article PDF–125K

Select item 523126817.

Single Nucleotide Variants of Candidate Genes in Aggrecan Metabolic Pathway Are Associated with Lumbar Disc Degeneration and Modic Changes

Romain Shanil Perera, Poruwalage Harsha Dissanayake, Upul Senarath, Lalith Sirimevan Wijayaratne, Aranjan Lional Karunanayake, Vajira Harshadeva Weerabaddana Dissanayake

PLoS One. 2017; 12(1): e0169835. Published online 2017 Jan 12. doi: 10.1371/journal.pone.0169835

PMCID:: PMC5231268

Abstract Article PDF–1.4M

Select item 503299818.

Semaphorin 4D Contributes to Rheumatoid Arthritis by Inducing Inflammatory Cytokine Production: Pathogenic and Therapeutic Implications

Yuji Yoshida, Atsushi Ogata, Sujin Kang, Kousuke Ebina, Kenrin Shi, Satoshi Nojima, Tetsuya Kimura, Daisuke Ito, Keiko Morimoto, Masayuki Nishide, Takashi Hosokawa, Toru Hirano, Yoshihito Shima, Masashi Narazaki, Hideki Tsuboi, Yukihiko Saeki, Tetsuya Tomita, Toshio Tanaka, Atsushi Kumanogoh

Arthritis Rheumatol. 2015 Jun; 67(6): 1481–1490. Published online 2015 May 25. doi: 10.1002/art.39086

PMCID:: PMC5032998

Abstract Article PDF–468K

Select item 476668119.

Progesterone acts via the progesterone receptor to induce adamts proteases in ovarian cancer cells

Maíra A. Lima, Suély V. da Silva, Vanessa M. Freitas

J Ovarian Res. 2016; 9: 9. Published online 2016 Feb 25. doi: 10.1186/s13048-016-0219-x

PMCID:: PMC4766681

Abstract Article PDF–3.8M

Select item 431297320.

ADAMTS-4_v1 Is a Splice Variant of ADAMTS-4 That Is Expressed as a Protein in Human Synovium and Cleaves Aggrecan at the Interglobular Domain

Shane D Wainwright, Jan Bondeson, Bruce Caterson, Clare E Hughes

Arthritis Rheum. 2013 Nov; 65(11): 2866–2875. Published online 2013 Oct 28. doi: 10.1002/art.38102

PMCID:: PMC4312973

Abstract Article PDF–584K

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