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Items: 1 to 20 of 391

1.
Proximity labeling reveals dynamic changes in the SQSTM1 protein network
Alejandro N. Rondón-Ortiz, Lushuang Zhang, Peter E.A. Ash, Avik Basu, Sambhavi Puri, Sophie J.F. van der Spek, Zihan Wang, Luke Dorrian, Andrew Emili, Benjamin Wolozin
J Biol Chem. 2024 Sep; 300(9): 107621. Published online 2024 Aug 3. doi: 10.1016/j.jbc.2024.107621
PMCID:
PMC11401034
AbstractArticlePDF–5.4M
2.
DSBSO-Based XL-MS Analysis of Breast Cancer PDX Tissues to Delineate Protein Interaction Network in Clinical Samples
Fenglong Jiao, Clinton Yu, Andrew Wheat, Lijun Chen, Tung-Shing Mamie Lih, Hui Zhang, Lan Huang
J Proteome Res. Author manuscript; available in PMC 2024 Aug 3.
Published in final edited form as: J Proteome Res. 2024 Aug 2; 23(8): 3269–3279. Published online 2024 Feb 9. doi: 10.1021/acs.jproteome.3c00832
PMCID:
PMC11296914
AbstractArticlePDF–1.7M
3.
CRL4DCAF1/VprBP E3 ubiquitin ligase controls ribosome biogenesis, cell proliferation, and development
Xiao-Ran Han, Naoya Sasaki, Sarah C. Jackson, Pu Wang, Zhijun Li, Matthew D. Smith, Ling Xie, Xian Chen, Yanping Zhang, William F. Marzluff, Yue Xiong
Sci Adv. 2020 Dec; 6(51): eabd6078. Published online 2020 Dec 18. doi: 10.1126/sciadv.abd6078
PMCID:
PMC11206221
AbstractArticlePDF–2.7M
4.
BRCA1 contributes to transcription‐coupled repair of DNA damage through polyubiquitination and degradation of Cockayne syndrome B protein
Leizhen Wei, Li Lan, Akira Yasui, Kiyoji Tanaka, Masafumi Saijo, Ayako Matsuzawa, Risa Kashiwagi, Emiko Maseki, Yiheng Hu, Jeffrey D. Parvin, Chikashi Ishioka, Natsuko Chiba
Cancer Sci. 2011 Oct; 102(10): 1840–1847. Published online 2011 Aug 18. doi: 10.1111/j.1349-7006.2011.02037.x
PMCID:
PMC11159811
AbstractArticlePDF–473K
5.
Ribosomal collision is not a prerequisite for ZNF598-mediated ribosome ubiquitination and disassembly of ribosomal complexes by ASCC
Anna Miścicka, Alexander G Bulakhov, Kazushige Kuroha, Alexandra Zinoviev, Christopher U T Hellen, Tatyana V Pestova
Nucleic Acids Res. 2024 May 8; 52(8): 4627–4643. Published online 2024 Feb 15. doi: 10.1093/nar/gkae087
PMCID:
PMC11077048
AbstractArticlePDF–1.7M
6.
The E3 ubiquitin ligase SMURF2 stabilizes RNA editase ADAR1p110 and promotes its adenosine-to-inosine (A-to-I) editing function
Praveen Koganti, Venkata Narasimha Kadali, Dhanoop Manikoth Ayyathan, Andrea Emanuelli, Biagio Paolini, Gal Levy-Cohen, Michael Blank
Cell Mol Life Sci. 2022 May; 79(5): 237. Published online 2022 Apr 11. doi: 10.1007/s00018-022-04272-8
PMCID:
PMC11072456
AbstractArticlePDF–6.5M
7.
Ring domains are essential for GATOR2-dependent mTORC1 activation
Cong Jiang, Xiaoming Dai, Shaohui He, Hongfei Zhou, Lan Fang, Jianping Guo, Songlei Liu, Tao Zhang, Weijuan Pan, Haihong Yu, Tianmin Fu, Dali Li, Hiroyuki Inuzuka, Ping Wang, Jianru Xiao, Wenyi Wei
Mol Cell. Author manuscript; available in PMC 2024 Apr 19.
Published in final edited form as: Mol Cell. 2023 Jan 5; 83(1): 74–89.e9. Published online 2022 Dec 16. doi: 10.1016/j.molcel.2022.11.021
PMCID:
PMC11027793
AbstractArticlePDF–3.0M
8.
Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates
Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert
Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644
PMCID:
PMC10565876
AbstractArticlePDF–3.7M
9.
Repression of TRIM13 by chromatin assembly factor CHAF1B is critical for AML development
Sarai T. Dean, Chiharu Ishikawa, Xiaoqin Zhu, Sean Walulik, Timothy Nixon, Jessica K. Jordan, Samantha Henderson, Michael Wyder, Nathan Salomonis, Mark Wunderlich, Kenneth D. Greis, Daniel T. Starczynowski, Andrew G. Volk
Blood Adv. 2023 Sep 12; 7(17): 4822–4837. Published online 2023 May 22. doi: 10.1182/bloodadvances.2022009438
PMCID:
PMC10469560
AbstractArticlePDF–4.2M
10.
Cryo‐EM structure of the chain‐elongating E3 ubiquitin ligase UBR5
Zuzana Hodáková, Irina Grishkovskaya, Hanna L Brunner, Derek L Bolhuis, Katarina Belačić, Alexander Schleiffer, Harald Kotisch, Nicholas G Brown, David Haselbach
EMBO J. 2023 Aug; 42(16): e113348. Published online 2023 Jul 6. doi: 10.15252/embj.2022113348
PMCID:
PMC10425842
AbstractArticlePDF–3.0M
11.
The E3 Ubiquitin Ligase SCF Cyclin F Promotes Sequestosome-1/p62 Insolubility and Foci Formation and is Dysregulated in ALS and FTD Pathogenesis
Jennilee M. Davidson, Sharlynn S. L. Wu, Stephanie L. Rayner, Flora Cheng, Kimberley Duncan, Carlo Russo, Michelle Newbery, Kunjie Ding, Natalie M. Scherer, Rachelle Balez, Alberto García-Redondo, Alberto Rábano, Livia Rosa-Fernandes, Lezanne Ooi, Kelly L. Williams, Marco Morsch, Ian P. Blair, Antonio Di Ieva, Shu Yang, Roger S. Chung, Albert Lee
Mol Neurobiol. 2023; 60(9): 5034–5054. Published online 2023 May 27. doi: 10.1007/s12035-023-03355-2
PMCID:
PMC10415446
AbstractArticlePDF–4.2M
12.
BRCA1/BARD1 intrinsically disordered regions facilitate chromatin recruitment and ubiquitylation
Samuel R Witus, Lisa M Tuttle, Wenjing Li, Alex Zelter, Meiling Wang, Klaiten E Kermoade, Damien B Wilburn, Trisha N Davis, Peter S Brzovic, Weixing Zhao, Rachel E Klevit
EMBO J. 2023 Aug; 42(15): e113565. Published online 2023 Jun 12. doi: 10.15252/embj.2023113565
PMCID:
PMC10390874
AbstractArticlePDF–2.4M
13.
TSG101 Physically Interacts with Linear Ubiquitin Chain Assembly Complex (LUBAC) and Upregulates the TNFα-Induced NF-κB Activation
Eunju Kim, Hyunchu Cho, Gaeul Lee, Heawon Baek, In Young Lee, Eui-Ju Choi
Mol Cells. 2023 Jul 31; 46(7): 430–440. Published online 2023 Jul 31. doi: 10.14348/molcells.2023.0026
PMCID:
PMC10336271
AbstractArticlePDF–1.9M
14.
Inflammasome activation and metabolic remodelling in p16‐positive aging cells aggravates high‐fat diet‐induced lung fibrosis by inhibiting NEDD4L‐mediated K48‐polyubiquitin‐dependent degradation of SGK1
Xin Gu, Haoyu Meng, Chengyi Peng, Shiyu Lin, Baihong Li, Lin Zhao, Xue Yang, Guangyan Wang, Wenyuan Cai, Jiawen Zhou, Shuiyuan Liu, Peng Wu, Yingqiang Du, Jianliang Jin, Xiaoyan Wang
Clin Transl Med. 2023 Jun; 13(6): e1308. Published online 2023 Jun 21. doi: 10.1002/ctm2.1308
PMCID:
PMC10285269
AbstractArticlePDF–20M
15.
HAPSTR1 localizes HUWE1 to the nucleus to limit stress signaling pathways
Julie K. Monda, Xuezhen Ge, Moritz Hunkeler, Katherine A. Donovan, Michelle W. Ma, Cyrus Y. Jin, Marilyn Leonard, Eric S. Fischer, Eric J. Bennett
Cell Rep. Author manuscript; available in PMC 2023 Jun 19.
Published in final edited form as: Cell Rep. 2023 May 30; 42(5): 112496. Published online 2023 May 9. doi: 10.1016/j.celrep.2023.112496
PMCID:
PMC10279472
AbstractArticlePDF–2.9M
16.
TRIM7/RNF90 promotes autophagy via regulation of ATG7 ubiquitination during L. monocytogenes infection
Jie Wang, Xiao Qin, Yulu Huang, Qunmei Zhang, Jinyong Pei, Yi Wang, Idan Goren, Shujun Ma, Zhishan Song, Yanzi Liu, Hongxia Xing, Hui Wang, Bo Yang
Autophagy. 2023; 19(6): 1844–1862. Published online 2023 Jan 1. doi: 10.1080/15548627.2022.2162706
PMCID:
PMC10262811
AbstractArticlePDF–7.7M
17.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
18.
Ubiquitinome Profiling Reveals in Vivo UBE2D3 Targets and Implicates UBE2D3 in Protein Quality Control
Zeliha Yalçin, Daniëlle Koot, Karel Bezstarosti, Daniel Salas-Lloret, Onno B. Bleijerveld, Vera Boersma, Mattia Falcone, Román González-Prieto, Maarten Altelaar, Jeroen A.A. Demmers, Jacqueline J.L. Jacobs
Mol Cell Proteomics. 2023 Jun; 22(6): 100548. Published online 2023 Apr 13. doi: 10.1016/j.mcpro.2023.100548
PMCID:
PMC10209342
AbstractArticlePDF–2.4M
19.
A ZFYVE21-Rubicon-RNF34 signaling complex promotes endosome-associated inflammasome activity in endothelial cells
Xue Li, Quan Jiang, Guiyu Song, Mahsa Nouri Barkestani, Qianxun Wang, Shaoxun Wang, Matthew Fan, Caodi Fang, Bo Jiang, Justin Johnson, Arnar Geirsson, George Tellides, Jordan S. Pober, Dan Jane-wit
Nat Commun. 2023; 14: 3002. Published online 2023 May 24. doi: 10.1038/s41467-023-38684-2
Correction in:
Nat Commun. 2023; 14: 3336.
Correction in:
Nat Commun. 2023; 14: 8404.
PMCID:
PMC10209169
AbstractArticlePDF–4.2M
20.
TRIB3 promotes pulmonary fibrosis through inhibiting SLUG degradation by physically interacting with MDM2
Xiaoxi Lv, Shanshan Liu, Chang Liu, Yunxuan Li, Tingting Zhang, Jie Qi, Ke Li, Fang Hua, Bing Cui, Xiaowei Zhang, Yuxin Liu, Jiaojiao Yu, Jinmei Yu, Li Li, Xia Li, Zhigang Yao, Bo Huang
Acta Pharm Sin B. 2023 Apr; 13(4): 1631–1647. Published online 2023 Jan 11. doi: 10.1016/j.apsb.2023.01.008
PMCID:
PMC10150180
AbstractArticlePDF–6.7M

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