PMC Links for GEO Profiles (Select 108390272) - PMC

Sang Hyun Lim, Jamie Snider, Liron Birimberg‐Schwartz, Wan Ip, Joana C Serralha, Hugo M Botelho, Miquéias Lopes‐Pacheco, Madalena C Pinto, Mohamed Taha Moutaoufik, Mara Zilocchi, Onofrio Laselva, Mohsen Esmaeili, Max Kotlyar, Anna Lyakisheva, Priscilla Tang, Lucía López Vázquez, Indira Akula, Farzaneh Aboualizadeh, Victoria Wong, Ingrid Grozavu, Teuta Opacak‐Bernardi, Zhong Yao, Meg Mendoza, Mohan Babu, Igor Jurisica, Tanja Gonska, Christine E Bear, Margarida D Amaral, Igor Stagljar

Mol Syst Biol. 2022 Feb; 18(2): e10629. Published online 2022 Feb 14. doi: 10.15252/msb.202110629

PMCID:: PMC8842165

Abstract Article PDF–3.0M

Select item 81650304.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 67567225.

Associations of IL-12, IL12R polymorphisms and serum IL-12 levels with high-risk human papillomavirus susceptibility in rural women from Luohe, Henan, China

Jiayu Song, Qingwei Zhang, Rong Wang, Mingzhen Sun, Shaoju Jin

Medicine (Baltimore) 2019 Sep; 98(38): e16991. Published online 2019 Sep 20. doi: 10.1097/MD.0000000000016991

PMCID:: PMC6756722

Abstract Article PDF–279K

Select item 64728846.

Three novel compound heterozygous IL12RB1 mutations in Chinese patients with Mendelian susceptibility to mycobacterial disease

Xiaopei Zhou, Weimin Jia, Zhengyi Ni, Ali Wang, Zhenxing Liu, Meiqi Hou, Mi Zhou, Zhongwen Tang, Dazhi Zhang, Lei Li, Tiantian Han, Yang Tan, Geng Luo, Jiarui Wang, Yanling Wu, Xianqin Zhang

PLoS One. 2019; 14(4): e0215648. Published online 2019 Apr 18. doi: 10.1371/journal.pone.0215648

PMCID:: PMC6472884

Abstract Article PDF–1.4M

Select item 64418687.

POH1 contributes to hyperactivation of TGF-β signaling and facilitates hepatocellular carcinoma metastasis through deubiquitinating TGF-β receptors and caveolin-1

Boshi Wang, Xiaoli Xu, Zhaojuan Yang, Li Zhang, Yun Liu, Aihui Ma, Guiqin Xu, Ming Tang, Tiantian Jing, Lin Wu, Yongzhong Liu

EBioMedicine. 2019 Mar; 41: 320–332. Published online 2019 Feb 7. doi: 10.1016/j.ebiom.2019.01.058

PMCID:: PMC6441868

Abstract Article PDF–7.0M

Select item 63296638.

A variety of Alu-mediated copy number variations can underlie IL-12Rβ1 deficiency

Jérémie Rosain, Carmen Oleaga-Quintas, Caroline Deswarte, Hannah Verdin, Stéphane Marot, Garyfallia Syridou, Mahboubeh Mansouri, Seyed A. Mahdaviani, Edna Venegas-Montoya, Maria Tsolia, Mehrnaz Mesdaghi, Liudmyla Chernyshova, Yuriy Stepanovskiy, Nima Parvaneh, Davood Mansouri, Sigifredo Pedraza-Sánchez, Anastasia Bondarenko, Sara E. Espinosa-Padilla, Marco A. Yamazaki-Nakashimada, Alejandro Nieto-Patlán, Gaspard Kerner, Nathalie Lambert, Corinne Jacques, Emilie Corvilain, Mélanie Migaud, Virginie Grandin, María T. Herrera, Fabienne Jabot-Hanin, Stéphanie Boisson-Dupuis, Capucine Picard, Patrick Nitschke, Anne Puel, Frederic Tores, Laurent Abel, Lizbeth Blancas Galicia, Elfride De Baere, Christine Bole-Feysot, Jean-Laurent Casanova, Jacinta Bustamante

J Clin Immunol. Author manuscript; available in PMC 2019 Jul 11.

Published in final edited form as: J Clin Immunol. 2018 Jul; 38(5): 617–627. Published online 2018 Jul 11. doi: 10.1007/s10875-018-0527-6

PMCID:: PMC6329663

Abstract Article PDF–1.0M

Select item 61657189.

Human IL12RB1 expression is allele-biased and produces a novel IL12 response regulator

Allison E. Reeme, Tiffany A. Claeys, Praful Aggarwal, Amy J. Turner, John M. Routes, Ulrich Broeckel, Richard T. Robinson

Genes Immun. Author manuscript; available in PMC 2018 Sep 30.

Published in final edited form as: Genes Immun. 2019 Mar; 20(3): 181–197. Published online 2018 Mar 30. doi: 10.1038/s41435-018-0023-2

PMCID:: PMC6165718

Abstract Article PDF–1.1M

Select item 594337010.

Susceptibility to mycobacterial disease due to mutations in IL-12Rβ1 in three Iranian patients

Maryam Alinejad Dizaj, Esmaeil Mortaz, Seyed Alireza Mahdaviani, Davood Mansouri, Payam Mehrian, Els M. Verhard, Mohammad Varahram, Delara Babaie, Ian M. Adcock, Johan Garssen, Esther van de Vosse, Aliakbar Velayati

Immunogenetics. 2018; 70(6): 373–379. Published online 2017 Dec 18. doi: 10.1007/s00251-017-1041-3

PMCID:: PMC5943370

Abstract Article PDF–1.5M

Select item 577337811.

Structural activation of pro-inflammatory human cytokine IL-23 by cognate IL-23 receptor enables recruitment of the shared receptor IL-12Rβ1

Yehudi Bloch, Laura Bouchareychas, Romain Merceron, Katarzyna Składanowska, Lien Van den Bossche, Sammy Detry, Srinath Govindarajan, Dirk Elewaut, Filomeen Haerynck, Melissa Dullaers, Iannis E. Adamopoulos, Savvas N. Savvides

Immunity. Author manuscript; available in PMC 2019 Jan 16.

Published in final edited form as: Immunity. 2018 Jan 16; 48(1): 45–58.e6. Published online 2017 Dec 26. doi: 10.1016/j.immuni.2017.12.008

PMCID:: PMC5773378

Abstract Article PDF–2.7M

Select item 553161112.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 538997513.

Microbial Disease Spectrum Linked to a Novel IL-12Rβ1 N-Terminal Signal Peptide Stop-Gain Homozygous Mutation with Paradoxical Receptor Cell-Surface Expression

Thais Louvain de Souza, Regina C. de Souza Campos Fernandes, Juliana Azevedo da Silva, Vladimir Gomes Alves Júnior, Adelia Gomes Coelho, Afonso C. Souza Faria, Nabia M. Moreira Salomão Simão, João T. Souto Filho, Caroline Deswarte, Stéphanie Boisson-Dupuis, Dara Torgerson, Jean-Laurent Casanova, Jacinta Bustamante, Enrique Medina-Acosta

Front Microbiol. 2017; 8: 616. Published online 2017 Apr 13. doi: 10.3389/fmicb.2017.00616

PMCID:: PMC5389975

Abstract Article PDF–4.6M

Select item 474567614.

A novel human truncated IL12rβ1-Fc fusion protein ameliorates experimental autoimmune encephalomyelitis via specific binding of p40 to inhibit Th1 and Th17 cell differentiation

Wei Guo, Chen Wang, Xin Wang, Cheng Luo, Dongmei Yu, Yuheng Wang, Yucong Chen, Wen Lei, Xiangdong Gao, Wenbing Yao

Oncotarget. 2015 Oct 6; 6(30): 28539–28555. Published online 2015 Sep 4. doi: 10.18632/oncotarget.5164

PMCID:: PMC4745676

Abstract Article PDF–6.4M

Select item 468759115.

The introduction of RNA-DNA differences underlies interindividual variation in the human IL12RB1 mRNA repertoire

Amy J. Turner, Praful Aggarwal, Halli E. Miller, Jill Waukau, John M. Routes, Ulrich Broeckel, Richard T. Robinson

Proc Natl Acad Sci U S A. 2015 Dec 15; 112(50): 15414–15419. Published online 2015 Nov 30. doi: 10.1073/pnas.1515978112

PMCID:: PMC4687591

Abstract Article PDF–1.4M

Select item 461721116.

The BioPlex Network: A Systematic Exploration of the Human Interactome

Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2016 Jul 16.

Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043

PMCID:: PMC4617211

Abstract Article PDF–2.2M

Select item 451645317.

Early coupled up-regulation of interleukin-12 receptor beta-1 in CD8⁺ central memory and effector T cells for better clinical outcomes in liver transplant recipients

S Uemoto, K Ozawa, T Kaido, A Mori, Y Fujimoto, K Ogawa

Clin Exp Immunol. 2015 Aug; 181(2): 373–384. Published online 2015 Jul 14. doi: 10.1111/cei.12588

PMCID:: PMC4516453

Abstract Article PDF–640K

Select item 434614118.

IL12Rβ1: The cytokine receptor that we used to know

Richard T. Robinson

Cytokine. Author manuscript; available in PMC 2016 Feb 1.

Published in final edited form as: Cytokine. 2015 Feb; 71(2): 348–359. Published online 2014 Dec 13. doi: 10.1016/j.cyto.2014.11.018

PMCID:: PMC4346141

Abstract Article PDF–1.6M

Select item 428173919.

Non-Canonical Interleukin 23 Receptor Complex Assembly: P40 PROTEIN RECRUITS INTERLEUKIN 12 RECEPTOR β1 VIA SITE II AND INDUCES P19/INTERLEUKIN 23 RECEPTOR INTERACTION VIA SITE III

Jutta Schröder, Jens M. Moll, Paul Baran, Joachim Grötzinger, Jürgen Scheller, Doreen M. Floss

J Biol Chem. 2015 Jan 2; 290(1): 359–370. Published online 2014 Nov 4. doi: 10.1074/jbc.M114.617597

PMCID:: PMC4281739

Abstract Article PDF–3.1M

Select item 424538320.

Identification of IL12RB1 as a novel systemic sclerosis susceptibility locus

Elena López-Isac, Lara Bossini-Castillo, Sandra G Guerra, Shervin Assassi, Xiaodong Zhou, Carmen Pilar Simeón, Norberto Ortego-Centeno, Iván Castellví, Patricia Carreira, the Spanish Scleroderma Group, Olga Gorlova, Lorenzo Beretta, Alessandro Santaniello, Claudio Lunardi, Roger Hesselstrand, Annika Nordin, Gabriela Riemekasten, Torsten Witte, Nicolas Hunzelmann, Alexander Kreuter, Jörg H.W. Distler, Alexandre E. Voskuyl, Jeska de Vries-Bouwstra, Bobby P. Koeleman, Ariane Herrick, Jane Worthington, Christopher Denton, Carmen Fonseca, Timothy RDJ Radstake, Maureen D. Mayes, Javier Martin

Arthritis Rheumatol. Author manuscript; available in PMC 2015 Dec 1.

Published in final edited form as: Arthritis Rheumatol. 2014 Dec; 66(12): 3521–3523. doi: 10.1002/art.38870

PMCID:: PMC4245383

Article PDF–112K

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