U.S. flag

An official website of the United States government

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Links from GEO Profiles

Items: 1 to 20 of 136

1.
Antagonistic roles of canonical and alternative-RPA in disease-associated tandem CAG repeat instability
Terence Gall-Duncan, Jennifer Luo, Carla-Marie Jurkovic, Laura A. Fischer, Kyota Fujita, Amit L. Deshmukh, Rachel J. Harding, Stephanie Tran, Mustafa Mehkary, Vanessa Li, David E. Leib, Ran Chen, Hikari Tanaka, Amanda G. Mason, Dominique Lévesque, Mahreen Khan, Mortezaali Razzaghi, Tanya Prasolava, Stella Lanni, Nozomu Sato, Marie-Christine Caron, Gagan B. Panigrahi, Peixiang Wang, Rachel Lau, Arturo López Castel, Jean-Yves Masson, Lynette Tippett, Clinton Turner, Maria Spies, Albert R. La Spada, Eric I. Campos, Maurice A. Curtis, François-Michel Boisvert, Richard L.M. Faull, Beverly L. Davidson, Masayuki Nakamori, Hitoshi Okazawa, Marc S. Wold, Christopher E. Pearson
Cell. Author manuscript; available in PMC 2024 Oct 26.
Published in final edited form as: Cell. 2023 Oct 26; 186(22): 4898–4919.e25. Published online 2023 Oct 11. doi: 10.1016/j.cell.2023.09.008
PMCID:
PMC11209935
AbstractArticlePDF–3.0M
2.
MRE11 and TREX1 control senescence by coordinating replication stress and interferon signaling
Hervé Técher, Diyavarshini Gopaul, Jonathan Heuzé, Nail Bouzalmad, Baptiste Leray, Audrey Vernet, Clément Mettling, Jérôme Moreaux, Philippe Pasero, Yea-Lih Lin
Nat Commun. 2024; 15: 5423. Published online 2024 Jun 26. doi: 10.1038/s41467-024-49740-w
PMCID:
PMC11208572
AbstractArticlePDF–1.6M
3.
TREX1 is required for microglial cholesterol homeostasis and oligodendrocyte terminal differentiation in human neural assembloids
Gabriela Goldberg, Luisa Coelho, Guoya Mo, Laura A. Adang, Meenakshi Patne, Zhoutao Chen, Ivan Garcia-Bassets, Pinar Mesci, Alysson R. Muotri
Mol Psychiatry. 2024; 29(3): 566–579. Published online 2023 Dec 21. doi: 10.1038/s41380-023-02348-w
PMCID:
PMC11153041
AbstractArticlePDF–2.8M
4.
Intratumoral TREX1 Induction Promotes Immune Evasion by Limiting Type I IFN
Eléonore Toufektchan, Alexandra Dananberg, Josefine Striepen, James H. Hickling, Abraham Shim, Yanyang Chen, Ashley Nichols, Mercedes A. Duran Paez, Lisa Mohr, Samuel F. Bakhoum, John Maciejowski
Cancer Immunol Res. 2024 Jun 4; 12(6): 673–686. Published online 2024 Feb 26. doi: 10.1158/2326-6066.CIR-23-1093
PMCID:
PMC11148545
AbstractArticlePDF–1.1M
5.
The Exonuclease TREX1 Constitutes an Innate Immune Checkpoint Limiting cGAS/STING-Mediated Antitumor Immunity
Junghyun Lim, Ryan Rodriguez, Katherine Williams, John Silva, Alan G. Gutierrez, Paul Tyler, Faezzah Baharom, Tao Sun, Eva Lin, Scott Martin, Brandon D. Kayser, Robert J. Johnston, Ira Mellman, Lélia Delamarre, Nathaniel R. West, Sören Müller, Yan Qu, Klaus Heger
Cancer Immunol Res. 2024 Jun 4; 12(6): 663–672. Published online 2024 Mar 15. doi: 10.1158/2326-6066.CIR-23-1078
PMCID:
PMC11148535
AbstractArticlePDF–6.5M
6.
Inherited C-terminal TREX1 variants disrupt homology-directed repair to cause senescence and DNA damage phenotypes in Drosophila, mice, and humans
Samuel D. Chauvin, Shoichiro Ando, Joe A. Holley, Atsushi Sugie, Fang R. Zhao, Subhajit Poddar, Rei Kato, Cathrine A. Miner, Yohei Nitta, Siddharth R. Krishnamurthy, Rie Saito, Yue Ning, Yuya Hatano, Sho Kitahara, Shin Koide, W. Alexander Stinson, Jiayuan Fu, Nehalee Surve, Lindsay Kumble, Wei Qian, Oleksiy Polishchuk, Prabhakar S. Andhey, Cindy Chiang, Guanqun Liu, Ludovic Colombeau, Raphaël Rodriguez, Nicolas Manel, Akiyoshi Kakita, Maxim N. Artyomov, David C. Schultz, P. Toby Coates, Elisha D. O. Roberson, Yasmine Belkaid, Roger A. Greenberg, Sara Cherry, Michaela U. Gack, Tristan Hardy, Osamu Onodera, Taisuke Kato, Jonathan J. Miner
Nat Commun. 2024; 15: 4696. Published online 2024 Jun 1. doi: 10.1038/s41467-024-49066-7
PMCID:
PMC11144269
AbstractArticlePDF–4.7M
7.
The Expression Levels of TREX1 and IFN-α Are Associated with Immune Reconstitution in HIV-1-Infected Individuals
Maria Alice Freitas Queiroz, Allysson Quintino Tenório de Oliveira, Tuane Carolina Ferreira Moura, Wandrey Roberto dos Santos Brito, Emmanuelle Giuliana Mendes Santana, Lorena Leticia Peixoto de Lima, Felipe Teixeira Lopes, Carlos David Araújo Bichara, Ednelza da Silva Graça Amoras, Ricardo Ishak, Izaura Maria Vieira Cayres Vallinoto, Antonio Carlos Rosário Vallinoto
Viruses. 2024 Apr; 16(4): 499. Published online 2024 Mar 25. doi: 10.3390/v16040499
PMCID:
PMC11054413
AbstractArticlePDF–4.1M
8.
TREX1 531C/T Polymorphism and Autoantibodies Associated with the Immune Status of HIV-1-Infected Individuals
Maria Alice Freitas Queiroz, Tuane Carolina Ferreira Moura, Carlos David Araújo Bichara, Lorena Leticia Peixoto de Lima, Allysson Quintino Tenório de Oliveira, Ranilda Gama de Souza, Samara Tatielle Monteiro Gomes, Ednelza da Silva Graça Amoras, Antonio Carlos Rosário Vallinoto
Int J Mol Sci. 2023 Jun; 24(11): 9660. Published online 2023 Jun 2. doi: 10.3390/ijms24119660
PMCID:
PMC10253649
AbstractArticlePDF–2.6M
9.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
10.
Cross-linking mass spectrometry discovers, evaluates, and corroborates structures and protein–protein interactions in the human cell
Tara K. Bartolec, Xabier Vázquez-Campos, Alexander Norman, Clement Luong, Marcus Johnson, Richard J. Payne, Marc R. Wilkins, Joel P. Mackay, Jason K. K. Low
Proc Natl Acad Sci U S A. 2023 Apr 25; 120(17): e2219418120. Published online 2023 Apr 18. doi: 10.1073/pnas.2219418120
PMCID:
PMC10151615
AbstractArticlePDF–2.9M
11.
Variants in ATRIP are associated with breast cancer susceptibility in the Polish population and UK Biobank
Cezary Cybulski, Neda Zamani, Wojciech Kluźniak, Larissa Milano, Dominika Wokołorczyk, Klaudia Stempa, Helena Rudnicka, Shiyu Zhang, Maryam Zadeh, Tomasz Huzarski, Anna Jakubowska, Tadeusz Dębniak, Marcin Lener, Marek Szwiec, Paweł Domagała, Amir Abbas Samani, Steven Narod, Jacek Gronwald, Jean-Yves Masson, Jan Lubiński, Mohammad R. Akbari
Am J Hum Genet. 2023 Apr 6; 110(4): 648–662. Published online 2023 Mar 27. doi: 10.1016/j.ajhg.2023.03.002
PMCID:
PMC10119148
AbstractArticlePDF–3.6M
12.
Assessment of community efforts to advance network-based prediction of protein–protein interactions
Xu-Wen Wang, Lorenzo Madeddu, Kerstin Spirohn, Leonardo Martini, Adriano Fazzone, Luca Becchetti, Thomas P. Wytock, István A. Kovács, Olivér M. Balogh, Bettina Benczik, Mátyás Pétervári, Bence Ágg, Péter Ferdinandy, Loan Vulliard, Jörg Menche, Stefania Colonnese, Manuela Petti, Gaetano Scarano, Francesca Cuomo, Tong Hao, Florent Laval, Luc Willems, Jean-Claude Twizere, Marc Vidal, Michael A. Calderwood, Enrico Petrillo, Albert-László Barabási, Edwin K. Silverman, Joseph Loscalzo, Paola Velardi, Yang-Yu Liu
Nat Commun. 2023; 14: 1582. Published online 2023 Mar 22. doi: 10.1038/s41467-023-37079-7
PMCID:
PMC10033937
AbstractArticlePDF–1.5M
13.
Structural basis of human TREX1 DNA degradation and autoimmune disease
Wen Zhou, Desmond Richmond-Buccola, Qiannan Wang, Philip J. Kranzusch
Nat Commun. 2022; 13: 4277. Published online 2022 Jul 25. doi: 10.1038/s41467-022-32055-z
PMCID:
PMC9314330
AbstractArticlePDF–1.8M
14.
ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1
Boris Simonetti, James L. Daly, Lorena Simón-Gracia, Katja Klein, Saroja Weeratunga, Carlos Antón-Plágaro, Allan Tobi, Lorna Hodgson, Philip A. Lewis, Kate J. Heesom, Deborah K. Shoemark, Andrew D. Davidson, Brett M. Collins, Tambet Teesalu, Yohei Yamauchi, Peter J. Cullen
Proc Natl Acad Sci U S A. 2022 Jun 21; 119(25): e2201980119. Published online 2022 Jun 13. doi: 10.1073/pnas.2201980119
PMCID:
PMC9231623
AbstractArticlePDF–6.0M
15.
Human TDP1, APE1 and TREX1 repair 3′-DNA–peptide/protein cross-links arising from abasic sites in vitro
Xiaoying Wei, Zhishuo Wang, Caroline Hinson, Kun Yang
Nucleic Acids Res. 2022 Apr 22; 50(7): 3638–3657. Published online 2022 Mar 29. doi: 10.1093/nar/gkac185
PMCID:
PMC9023300
AbstractArticlePDF–4.6M
16.
TREX1 degrades the 3′ end of the small DNA oligonucleotide products of nucleotide excision repair in human cells
Seon Hee Kim, Geun Hoe Kim, Michael G Kemp, Jun-Hyuk Choi
Nucleic Acids Res. 2022 Apr 22; 50(7): 3974–3984. Published online 2022 Mar 31. doi: 10.1093/nar/gkac214
PMCID:
PMC9023299
AbstractArticlePDF–3.8M
17.
Hepatitis B virus nucleocapsid uncoating: biological consequences and regulation by cellular nucleases
Jin Hu, Liudi Tang, Junjun Cheng, Tianlun Zhou, Yuhuan Li, Jinhong Chang, Qiong Zhao, Ju-Tao Guo
Emerg Microbes Infect. 2021; 10(1): 852–864. Published online 2021 May 1. doi: 10.1080/22221751.2021.1919034
PMCID:
PMC8812769
AbstractArticlePDF–1.7M
18.
Carboplatin activates the cGAS-STING pathway by upregulating the TREX-1 (three prime repair exonuclease 1) expression in human melanoma
Zhourui Ma, Qianwei Xiong, Hongliang Xia, Wei Liu, Shu Dai, Shizhong Cai, Zhenhong Zhu, Xiangming Yan
Bioengineered. 2021; 12(1): 6448–6458. Published online 2021 Sep 14. doi: 10.1080/21655979.2021.1972198
PMCID:
PMC8806763
AbstractArticlePDF–2.5M
19.
Differential roles of ATR and ATM in p53, Chk1, and histone H2AX phosphorylation in response to hyperoxia: ATR-dependent ATM activation
Amit Kulkarni, Kumuda C. Das
Am J Physiol Lung Cell Mol Physiol. Author manuscript; available in PMC 2022 Jan 24.
Published in final edited form as: Am J Physiol Lung Cell Mol Physiol. 2008 May; 294(5): L998–L1006. Published online 2008 Mar 14. doi: 10.1152/ajplung.00004.2008
PMCID:
PMC8786037
AbstractArticlePDF–1.8M
20.
BioID reveals an ATG9A interaction with ATG13‐ATG101 in the degradation of p62/SQSTM1‐ubiquitin clusters
Ashari R Kannangara, Daniel M Poole, Colten M McEwan, Joshua C Youngs, Vajira K Weerasekara, Alex M Thornock, Misael T Lazaro, Eranga R Balasooriya, Laura M Oh, Erik J Soderblom, Jonathan J Lee, Daniel L Simmons, Joshua L Andersen
EMBO Rep. 2021 Oct 5; 22(10): e51136. Published online 2021 Aug 9. doi: 10.15252/embr.202051136
PMCID:
PMC8490997
AbstractArticlePDF–4.5M

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Filter your results:

Find related data

Recent activity

You are here: NCBI > Literature > PubMed Central (PMC)
Support Center