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Select item 116173781.

The role of the tricellular junction protein ILDR2 in glomerulopathies: Expression patterns and functional insights

Florian Siegerist, Felix Kliewe, Elke Hammer, Paul Schakau, Joanne Ern Chi Soh, Claudia Weber, Maja Lindenmeyer, Simone Reichelt-Wurm, Vedran Drenic, Christos Chatziantoniou, Christos E. Chadjichristos, Yiying Zhang, Stefan Simm, Miriam C. Banas, Matthias Nauck, Uwe Völker, Nicole Endlich

iScience. 2024 Dec 20; 27(12): 111329. Published online 2024 Nov 7. doi: 10.1016/j.isci.2024.111329

PMCID:: PMC11617378

Article PDF–6.6M

Select item 112460622.

Hepatic ketogenesis is not required for starvation adaptation in mice

Kyle Feola, Andrea H. Venable, Tatyana Broomfield, Morgan Villegas, Xiaorong Fu, Shawn Burgess, Sarah C. Huen

Mol Metab. 2024 Aug; 86: 101967. Published online 2024 Jun 12. doi: 10.1016/j.molmet.2024.101967

PMCID:: PMC11246062

Article PDF–3.8M

Select item 110963823.

Hepatocytes differentiate into intestinal epithelial cells through a hybrid epithelial/mesenchymal cell state in culture

Shizuka Miura, Kenichi Horisawa, Tokuko Iwamori, Satoshi Tsujino, Kazuya Inoue, Satsuki Karasawa, Junpei Yamamoto, Yasuyuki Ohkawa, Sayaka Sekiya, Atsushi Suzuki

Nat Commun. 2024; 15: 3940. Published online 2024 May 15. doi: 10.1038/s41467-024-47869-2

PMCID:: PMC11096382

Article PDF–11M

Select item 110871134.

Hepatocyte-specific METTL3 ablation by Alb-iCre mice (GPT), but not by Alb-Cre mice (JAX), resulted in acute liver failure (ALF) and postnatal lethality

Shihao Huang, Yingchun Li, Bingjie Wang, Zhihao Zhou, Yonglong Li, Lingjun Shen, Jinge Cong, Liuxin Han, Xudong Xiang, Jiawei Xia, Danhua He, Zhanlin Zhao, Ying Zhou, Qiwen Li, Guanqi Dai, Hanzhang Shen, Taoyan Lin, Aibing Wu, Junshuang Jia, Dong Xiao, Jing Li, Wentao Zhao, Xiaolin Lin

Aging (Albany NY) 2024 Apr 30; 16(8): 7217–7248. Published online 2024 Apr 22. doi: 10.18632/aging.205753

PMCID:: PMC11087113

Article PDF–3.9M

Select item 109608175.

Maternal RNA transcription in Dlk1-Dio3 domain is critical for proper development of the mouse placental vasculature

Ximeijia Zhang, Hongjuan He, Haoran Yu, Xiangqi Teng, Ziwen Wang, Chenghao Li, Jiahang Li, Haopeng Yang, Jiwei Shen, Tong Wu, Fengwei Zhang, Yan Zhang, Qiong Wu

Commun Biol. 2024; 7: 363. Published online 2024 Mar 23. doi: 10.1038/s42003-024-06038-3

PMCID:: PMC10960817

Article PDF–3.1M

Select item 109430856.

TANGO6 regulates cell proliferation via COPI vesicle-mediated RPB2 nuclear entry

Zhi Feng, Shengnan Liu, Ming Su, Chunyu Song, Chenyu Lin, Fangying Zhao, Yang Li, Xianyan Zeng, Yong Zhu, Yu Hou, Chunguang Ren, Huan Zhang, Ping Yi, Yong Ji, Chao Wang, Hongtao Li, Ming Ma, Lingfei Luo, Li Li

Nat Commun. 2024; 15: 2371. Published online 2024 Mar 15. doi: 10.1038/s41467-024-46720-y

PMCID:: PMC10943085

Article PDF–6.1M

Select item 109421087.

Increased genomic instability and reshaping of tissue microenvironment underlie oncogenic properties of Arid1a mutations

Alessandro D’Ambrosio, Davide Bressan, Elisa Ferracci, Francesco Carbone, Patrizia Mulè, Federico Rossi, Caterina Barbieri, Elisa Sorrenti, Gaia Fiaccadori, Thomas Detone, Elena Vezzoli, Salvatore Bianchi, Chiara Sartori, Simona Corso, Akihisa Fukuda, Giovanni Bertalot, Andrea Falqui, Mattia Barbareschi, Alessandro Romanel, Diego Pasini, Fulvio Chiacchiera

Sci Adv. 2024 Mar 15; 10(11): eadh4435. Published online 2024 Mar 15. doi: 10.1126/sciadv.adh4435

PMCID:: PMC10942108

Article PDF–9.8M

Select item 109172738.

Performance evaluation of different albumin assays for the detection of analbuminemia

Yi Zhang, Afsoun Abdollahi, Chaylen Andolino, Keigo Tomoo, Bailey M. Foster, Uma K. Aryal, Gregory C. Henderson

PLoS One. 2024; 19(3): e0300130. Published online 2024 Mar 6. doi: 10.1371/journal.pone.0300130

PMCID:: PMC10917273

Article PDF–987K

Select item 109075789.

NOTCH localizes to mitochondria through the TBC1D15-FIS1 interaction and is stabilized via blockade of E3 ligase and CDK8 recruitment to reprogram tumor-initiating cells

Hye Yeon Choi, Yicheng Zhu, Xuyao Zhao, Simran Mehta, Juan Carlos Hernandez, Jae-Jin Lee, Yi Kou, Risa Machida, Mauro Giacca, Giannino Del Sal, Ratna Ray, Hyungjin Eoh, Stanley M. Tahara, Lin Chen, Hidekazu Tsukamoto, Keigo Machida

Exp Mol Med. 2024 Feb; 56(2): 461–477. Published online 2024 Feb 27. doi: 10.1038/s12276-024-01174-6

Correction in:: Exp Mol Med. 2024 Oct; 56(10): 2323.

PMCID:: PMC10907578

Article PDF–9.4M

Select item 1083048310.

HNF4A guides the MLL4 complex to establish and maintain H3K4me1 at gene regulatory elements

Avinash Thakur, Kwangjin Park, Rebecca Cullum, Bettina M. Fuglerud, Mina Khoshnoodi, Sibyl Drissler, Tabea L. Stephan, Jeremy Lotto, Donghwan Kim, Frank J. Gonzalez, Pamela A. Hoodless

Commun Biol. 2024; 7: 144. Published online 2024 Jan 31. doi: 10.1038/s42003-024-05835-0

PMCID:: PMC10830483

Article PDF–13M

Select item 1080892711.

Salvianolic acid B attenuates liver fibrosis by targeting Ecm1 and inhibiting hepatocyte ferroptosis

Yadong Fu, Xiaoxi Zhou, Lin Wang, Weiguo Fan, Siqi Gao, Danyan Zhang, Zhiyang Ling, Yaguang Zhang, Liyan Ma, Fang Bai, Jiamei Chen, Bing Sun, Ping Liu

Redox Biol. 2024 Feb; 69: 103029. Published online 2024 Jan 3. doi: 10.1016/j.redox.2024.103029

PMCID:: PMC10808927

Article PDF–18M

Select item 1078974212.

ZBTB7B is a permissive regulator of hepatocellular carcinoma initiation by repressing c-Jun expression and function

Yue Zhu, Qinqin Wang, Xinyu Xie, Cuihong Ma, Yuemei Qiao, Yu Zhang, Yanjun Wu, Yuan Gao, Jing Jiang, Xin Liu, Jianfeng Chen, Chen Li, Gaoxiang Ge

Cell Death Dis. 2024 Jan; 15(1): 55. Published online 2024 Jan 15. doi: 10.1038/s41419-024-06441-y

PMCID:: PMC10789742

Article PDF–8.7M

Select item 1065189613.

BRISC is required for optimal activation of NF-κB in Kupffer cells induced by LPS and contributes to acute liver injury

Wen Zhang, Kai Liu, Guang-Ming Ren, Yu Wang, Ting Wang, Xian Liu, Dong-Xu Li, Yang Xiao, Xu Chen, Ya-Ting Li, Yi-Qun Zhan, Shen-Si Xiang, Hui Chen, Hui-Ying Gao, Ke Zhao, Miao Yu, Chang-Hui Ge, Chang-Yan Li, Zhi-Qiang Ge, Xiao-Ming Yang, Rong-Hua Yin

Cell Death Dis. 2023 Nov; 14(11): 743. Published online 2023 Nov 15. doi: 10.1038/s41419-023-06268-z

PMCID:: PMC10651896

Article PDF–6.5M

Select item 1056926214.

Specific Temporal Requirement of Prox1 Activity During Pancreatic Acinar Cell Development

Angelica S. Martinez-Ramirez, Thomas L. Borders, Leena Paul, Matthew Schipma, Xinkun Wang, Farida Korobova, Christopher V. Wright, Beatriz Sosa-Pineda

Gastro Hep Adv. 2022; 1(5): 807–823. Published online 2022 May 26. doi: 10.1016/j.gastha.2022.05.013

PMCID:: PMC10569262

Article PDF–6.7M

Select item 1030789515.

UHRF1 inhibition epigenetically reprograms cancer stem cells to suppress the tumorigenic phenotype of hepatocellular carcinoma

Yanchen Wang, Pengchao Hu, Fenfen Wang, Shaoyan Xi, Shasha Wu, Liangzhan Sun, Yuyang Du, Jingyi Zheng, Hui Yang, Mao Tang, Han Gao, Hao Luo, Yue Lv, Jingsong Yan, Xijun Ou, Yan Li

Cell Death Dis. 2023 Jun; 14(6): 381. Published online 2023 Jun 28. doi: 10.1038/s41419-023-05895-w

PMCID:: PMC10307895

Article PDF–6.9M

Select item 1030785216.

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility

Juan Gu, Pingyang Ke, Haokun Guo, Jing Liu, Yan Liu, Xin Tian, Zhuo Huang, Xin Xu, Demei Xu, Yuanlin Ma, Xuefeng Wang, Fei Xiao

Cell Death Differ. 2023 Jul; 30(7): 1726–1741. Published online 2023 May 4. doi: 10.1038/s41418-023-01174-5

PMCID:: PMC10307852

Article PDF–8.8M

Select item 1030762417.

Defining blood-induced microglia functions in neurodegeneration through multiomic profiling

Andrew S. Mendiola, Zhaoqi Yan, Karuna Dixit, Jeffrey R. Johnson, Mehdi Bouhaddou, Anke Meyer-Franke, Min-Gyoung Shin, Yu Yong, Ayushi Agrawal, Eilidh MacDonald, Gayathri Muthukumar, Clairice Pearce, Nikhita Arun, Belinda Cabriga, Rosa Meza-Acevedo, Maria del Pilar S. Alzamora, Scott S. Zamvil, Alexander R. Pico, Jae Kyu Ryu, Nevan J. Krogan, Katerina Akassoglou

Nat Immunol. 2023; 24(7): 1173–1187. Published online 2023 Jun 8. doi: 10.1038/s41590-023-01522-0

PMCID:: PMC10307624

Article PDF–18M

Select item 1027216618.

Albumosomes formed by cytoplasmic pre-folding albumin maintain mitochondrial homeostasis and inhibit nonalcoholic fatty liver disease

Boyuan Ma, Anji Ju, Shaosen Zhang, Qi An, Siran Xu, Jie Liu, Li Yu, Yan Fu, Yongzhang Luo

Signal Transduct Target Ther. 2023; 8: 229. Published online 2023 Jun 16. doi: 10.1038/s41392-023-01437-0

PMCID:: PMC10272166

Article PDF–8.8M

Select item 997447419.

The circadian demethylation of a unique intronic deoxymethylCpG-rich island boosts the transcription of its cognate circadian clock output gene

Nisha Misra, Manohar Damara, Tao Ye, Pierre Chambon

Proc Natl Acad Sci U S A. 2023 Feb 21; 120(8): e2214062120. Published online 2023 Feb 15. doi: 10.1073/pnas.2214062120

PMCID:: PMC9974474

Article PDF–1.1M

Select item 983932920.

A conditional Smg6 mutant mouse model reveals circadian clock regulation through the nonsense-mediated mRNA decay pathway

Georgia Katsioudi, René Dreos, Enes S. Arpa, Sevasti Gaspari, Angelica Liechti, Miho Sato, Christian H. Gabriel, Achim Kramer, Steven A. Brown, David Gatfield

Sci Adv. 2023 Jan; 9(2): eade2828. Published online 2023 Jan 13. doi: 10.1126/sciadv.ade2828

PMCID:: PMC9839329

Article PDF–2.3M

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