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Items: 1 to 20 of 77

1.
RECQL4 is not critical for firing of human DNA replication origins
Laura Padayachy, Sotirios G. Ntallis, Thanos D. Halazonetis
Sci Rep. 2024; 14: 7708. Published online 2024 Apr 2. doi: 10.1038/s41598-024-58404-0
PMCID:
PMC10987555
AbstractArticlePDF–1.8M
2.
Recognition and coacervation of G-quadruplexes by a multifunctional disordered region in RECQ4 helicase
Anna C. Papageorgiou, Michaela Pospisilova, Jakub Cibulka, Raghib Ashraf, Christopher A. Waudby, Pavel Kadeřávek, Volha Maroz, Karel Kubicek, Zbynek Prokop, Lumir Krejci, Konstantinos Tripsianes
Nat Commun. 2023; 14: 6751. Published online 2023 Oct 24. doi: 10.1038/s41467-023-42503-z
PMCID:
PMC10598209
AbstractArticlePDF–3.0M
3.
Hyperubiquitylation of DNA helicase RECQL4 by E3 ligase MITOL prevents mitochondrial entry and potentiates mitophagy
Mansoor Hussain, Aftab Mohammed, Shabnam Saifi, Swati Priya, Sagar Sengupta
J Biol Chem. 2023 Sep; 299(9): 105087. Published online 2023 Jul 24. doi: 10.1016/j.jbc.2023.105087
PMCID:
PMC10470078
AbstractArticlePDF–5.1M
4.
TRIM58 functions as a tumor suppressor in colorectal cancer by promoting RECQL4 ubiquitination to inhibit the AKT signaling pathway
Naizhi Sun, Jiacheng Shen, Yuhua Shi, Biao Liu, Shengguo Gao, Yichuan Chen, Jinwei Sun
World J Surg Oncol. 2023; 21: 231. Published online 2023 Jul 29. doi: 10.1186/s12957-023-03124-4
PMCID:
PMC10385910
AbstractArticlePDF–5.2M
5.
A Novel Germline Pathogenic Variant of RECQL4 Gene in an Iranian Pedigree with Familial Squamous Cell Carcinoma: A Brief Report
Mina Amin, Elaheh Mahmoodi-Khaledi, Sina Narrei, Mehrdad Zeinalian
Iran J Med Sci. 2023 Jul; 48(4): 420–424. doi: 10.30476/IJMS.2022.94539.2587
PMCID:
PMC10349162
AbstractArticlePDF–593K
6.
Deubiquitinase USP2 stabilizes the MRE11–RAD50–NBS1 complex at DNA double-strand break sites by counteracting the ubiquitination of NBS1
Hyunsup Kim, Dongmin Kim, Hyemin Choi, Gwangsu Shin, Joon-Kyu Lee
J Biol Chem. 2023 Jan; 299(1): 102752. Published online 2022 Nov 25. doi: 10.1016/j.jbc.2022.102752
PMCID:
PMC9758435
AbstractArticlePDF–2.6M
7.
RecQ-like helicase 4 (RECQL4) exacerbates resistance to oxaliplatin in colon adenocarcinoma via activation of the PI3K/AKT signaling pathway
Fei Zhou, Leiming Wang, Kangpeng Jin, Yang Wu
Bioengineered. 2021; 12(1): 5859–5869. Published online 2021 Sep 3. doi: 10.1080/21655979.2021.1964156
PMCID:
PMC8806715
AbstractArticlePDF–5.1M
8.
RNA binding protein serine/arginine splicing factor 1 promotes the proliferation, migration and invasion of hepatocellular carcinoma by interacting with RecQ protein-like 4 mRNA
Ying Ye, Feng Yu, Zhao Li, Yaping Xie, Xiaohong Yu
Bioengineered. 2021; 12(1): 6144–6154. Published online 2021 Sep 4. doi: 10.1080/21655979.2021.1972785
PMCID:
PMC8806490
AbstractArticlePDF–2.6M
9.
Patient-derived iPSCs link elevated mitochondrial respiratory complex I function to osteosarcoma in Rothmund-Thomson syndrome
Brittany E. Jewell, An Xu, Dandan Zhu, Mo-Fan Huang, Linchao Lu, Mo Liu, Erica L. Underwood, Jun Hyoung Park, Huihui Fan, Julian A. Gingold, Ruoji Zhou, Jian Tu, Zijun Huo, Ying Liu, Weidong Jin, Yi-Hung Chen, Yitian Xu, Shu-Hsia Chen, Nino Rainusso, Nathaniel K. Berg, Danielle A. Bazer, Christopher Vellano, Philip Jones, Holger K. Eltzschig, Zhongming Zhao, Benny Abraham Kaipparettu, Ruiying Zhao, Lisa L. Wang, Dung-Fang Lee
PLoS Genet. 2021 Dec; 17(12): e1009971. Published online 2021 Dec 29. doi: 10.1371/journal.pgen.1009971
PMCID:
PMC8716051
AbstractArticlePDF–3.8M
10.
Role and Regulation of the RECQL4 Family during Genomic Integrity Maintenance
Thong T. Luong, Kara A. Bernstein
Genes (Basel) 2021 Dec; 12(12): 1919. Published online 2021 Nov 29. doi: 10.3390/genes12121919
PMCID:
PMC8701316
AbstractArticlePDF–1.5M
11.
The conserved Tpk1 regulates non-homologous end joining double-strand break repair by phosphorylation of Nej1, a homolog of the human XLF
Matthew Jessulat, Shahreen Amin, Mohsen Hooshyar, Ramy Malty, Mohamed Taha Moutaoufik, Mara Zilocchi, Zoe Istace, Sadhna Phanse, Hiroyuki Aoki, Katayoun Omidi, Daniel Burnside, Bahram Samanfar, Khaled A Aly, Ashkan Golshani, Mohan Babu
Nucleic Acids Res. 2021 Aug 20; 49(14): 8145–8160. Published online 2021 Jul 9. doi: 10.1093/nar/gkab585
PMCID:
PMC8373142
AbstractArticlePDF–2.0M
12.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
13.
DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity
Rajat Gupta, Kumar Somyajit, Takeo Narita, Elina Maskey, Andre Stanlie, Magdalena Kremer, Dimitris Typas, Michael Lammers, Niels Mailand, Andre Nussenzweig, Jiri Lukas, Chunaram Choudhary
Cell. Author manuscript; available in PMC 2021 May 10.
Published in final edited form as: Cell. 2018 May 3; 173(4): 972–988.e23. Published online 2018 Apr 12. doi: 10.1016/j.cell.2018.03.050
PMCID:
PMC8108093
AbstractArticlePDF–3.5M
14.
RNF8 ubiquitinates RecQL4 and promotes its dissociation from DNA double strand breaks
Qunsong Tan, Kaifeng Niu, Yuqi Zhu, Zixiang Chen, Yueyang Li, Mengge Li, Di Wei, Adayabalam S. Balajee, Hongbo Fang, Yongliang Zhao
Oncogenesis. 2021 Mar; 10(3): 24. Published online 2021 Mar 5. doi: 10.1038/s41389-021-00315-0
PMCID:
PMC7935965
AbstractArticlePDF–1.8M
15.
RECQL4 regulates DNA damage response and redox homeostasis in esophageal cancer
Guosheng Lyu, Peng Su, Xiaohe Hao, Shiming Chen, Shuai Ren, Zixiao Zhao, Yaoqin Gong, Qiao Liu, Changshun Shao
Cancer Biol Med. 2021 Feb 15; 18(1): 120–138. Published online 2021 Feb 15. doi: 10.20892/j.issn.2095-3941.2020.0105
PMCID:
PMC7877169
AbstractArticlePDF–1.4M
16.
Pathogenic mutations reveal a role of RECQ4 in mitochondrial RNA:DNA hybrid formation and resolution
Chou-Wei Chang, Xiaohua Xu, Min Li, Di Xin, Lin Ding, Ya-Ting Wang, Yilun Liu
Sci Rep. 2020; 10: 17033. Published online 2020 Oct 12. doi: 10.1038/s41598-020-74095-9
PMCID:
PMC7552406
AbstractArticlePDF–6.9M
17.
Interaction between RECQL4 and OGG1 promotes repair of oxidative base lesion 8-oxoG and is regulated by SIRT1 deacetylase
Shunlei Duan, Xuerui Han, Mansour Akbari, Deborah L Croteau, Lene Juel Rasmussen, Vilhelm A Bohr
Nucleic Acids Res. 2020 Jul 9; 48(12): 6530–6546. Published online 2020 May 20. doi: 10.1093/nar/gkaa392
PMCID:
PMC7337523
AbstractArticlePDF–5.6M
18.
The cooperative action of CSB, CSA, and UVSSA target TFIIH to DNA damage-stalled RNA polymerase II
Yana van der Weegen, Hadar Golan-Berman, Tycho E. T. Mevissen, Katja Apelt, Román González-Prieto, Joachim Goedhart, Elisheva E. Heilbrun, Alfred C. O. Vertegaal, Diana van den Heuvel, Johannes C. Walter, Sheera Adar, Martijn S. Luijsterburg
Nat Commun. 2020; 11: 2104. Published online 2020 Apr 30. doi: 10.1038/s41467-020-15903-8
Correction in:
Nat Commun. 2020; 11: 5734.
PMCID:
PMC7192910
AbstractArticlePDF–4.5M
19.
RecQL4 tethering on the pre-replicative complex induces unscheduled origin activation and replication stress in human cells
Gwangsu Shin, Dongsoo Jeong, Hyunsup Kim, Jun-Sub Im, Joon-Kyu Lee
J Biol Chem. 2019 Nov 1; 294(44): 16255–16265. Published online 2019 Sep 13. doi: 10.1074/jbc.RA119.009996
PMCID:
PMC6827294
AbstractArticlePDF–2.2M
20.
Enrichment of heterozygous germline RECQL4 loss-of-function variants in pediatric osteosarcoma
Jamie L. Maciaszek, Ninad Oak, Wenan Chen, Kayla V. Hamilton, Rose B. McGee, Regina Nuccio, Roya Mostafavi, Stacy Hines-Dowell, Lynn Harrison, Leslie Taylor, Elsie L. Gerhardt, Annastasia Ouma, Michael N. Edmonson, Aman Patel, Joy Nakitandwe, Alberto S. Pappo, Elizabeth M. Azzato, Sheila A. Shurtleff, David W. Ellison, James R. Downing, Melissa M. Hudson, Leslie L. Robison, Victor Santana, Scott Newman, Jinghui Zhang, Zhaoming Wang, Gang Wu, Kim E. Nichols, Chimene A. Kesserwan
Cold Spring Harb Mol Case Stud. 2019 Oct; 5(5): a004218. doi: 10.1101/mcs.a004218
PMCID:
PMC6824257
AbstractArticlePDF–2.3M

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