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Items: 1 to 20 of 68

1.
Prognostic significance of L‐type amino acid transporter 1 (LAT1) and 4F2 heavy chain (CD98) expression in early stage squamous cell carcinoma of the lung
Kyoichi Kaira, Noboru Oriuchi, Hisao Imai, Kimihiro Shimizu, Noriko Yanagitani, Noriaki Sunaga, Takeshi Hisada, Tamotsu Ishizuka, Yoshikatsu Kanai, Hitoshi Endou, Takashi Nakajima, Masatomo Mori
Cancer Sci. 2009 Feb; 100(2): 249–254. Published online 2008 Dec 5. doi: 10.1111/j.1349-7006.2008.01029.x
PMCID:
PMC11159214
AbstractArticlePDF–323K
2.
Assessment of community efforts to advance network-based prediction of protein–protein interactions
Xu-Wen Wang, Lorenzo Madeddu, Kerstin Spirohn, Leonardo Martini, Adriano Fazzone, Luca Becchetti, Thomas P. Wytock, István A. Kovács, Olivér M. Balogh, Bettina Benczik, Mátyás Pétervári, Bence Ágg, Péter Ferdinandy, Loan Vulliard, Jörg Menche, Stefania Colonnese, Manuela Petti, Gaetano Scarano, Francesca Cuomo, Tong Hao, Florent Laval, Luc Willems, Jean-Claude Twizere, Marc Vidal, Michael A. Calderwood, Enrico Petrillo, Albert-László Barabási, Edwin K. Silverman, Joseph Loscalzo, Paola Velardi, Yang-Yu Liu
Nat Commun. 2023; 14: 1582. Published online 2023 Mar 22. doi: 10.1038/s41467-023-37079-7
PMCID:
PMC10033937
AbstractArticlePDF–1.5M
3.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
4.
The IMiD target CRBN determines HSP90 activity toward transmembrane proteins essential in multiple myeloma
Michael Heider, Ruth Eichner, Jacob Stroh, Volker Morath, Anna Kuisl, Jana Zecha, Jannis Lawatscheck, Kheewoong Baek, Anne-Kathrin Garz, Martina Rudelius, Friedrich-Christian Deuschle, Ulrich Keller, Simone Lemeer, Mareike Verbeek, Katharina S. Götze, Arne Skerra, Wolfgang A. Weber, Johannes Buchner, Brenda A. Schulman, Bernhard Kuster, Vanesa Fernández-Sáiz, Florian Bassermann
Mol Cell. 2021 Mar 18; 81(6): 1170–1186.e10. doi: 10.1016/j.molcel.2020.12.046
PMCID:
PMC7980223
AbstractArticle
5.
Retrograde and Anterograde Transport of Lat-Vesicles during the Immunological Synapse Formation: Defining the Finely-Tuned Mechanism
Juan José Saez, Stephanie Dogniaux, Massiullah Shafaq-Zadah, Ludger Johannes, Claire Hivroz, Andrés Ernesto Zucchetti
Cells. 2021 Feb; 10(2): 359. Published online 2021 Feb 9. doi: 10.3390/cells10020359
PMCID:
PMC7916135
AbstractArticlePDF–3.3M
6.
A Novel, LAT/Lck Double Deficient T Cell Subline J.CaM1.7 for Combined Analysis of Early TCR Signaling
Inmaculada Vico-Barranco, Mikel M. Arbulo-Echevarria, Isabel Serrano-García, Alba Pérez-Linaza, José M. Miranda-Sayago, Arkadiusz Miazek, Isaac Narbona-Sánchez, Enrique Aguado
Cells. 2021 Feb; 10(2): 343. Published online 2021 Feb 6. doi: 10.3390/cells10020343
PMCID:
PMC7915312
AbstractArticlePDF–2.3M
7.
The Membrane Proximal Proline-Rich Region and Correct Order of C-Terminal Tyrosines on the Adaptor Protein LAT Are Required For TCR-Mediated Signaling and Downstream Functions
Mikaela M. Tremblay, Tomye Ollinger, Jon C.D. Houtman
Cell Signal. Author manuscript; available in PMC 2021 Dec 1.
Published in final edited form as: Cell Signal. 2020 Dec; 76: 109790. Published online 2020 Sep 23. doi: 10.1016/j.cellsig.2020.109790
PMCID:
PMC7669716
AbstractArticlePDF–1.0M
8.
LRCH1 deficiency enhances LAT signalosome formation and CD8+ T cell responses against tumors and pathogens
Chang Liu, Xiaoyan Xu, Lei Han, Xiaopeng Wan, Lingming Zheng, Chunyang Li, Zhaohui Liao, Jun Xiao, Ruiyue Zhong, Xin Zheng, Qiong Wang, Zonghai Li, Hualan Chen, Bin Wei, Hongyan Wang
Proc Natl Acad Sci U S A. 2020 Aug 11; 117(32): 19388–19398. Published online 2020 Jul 29. doi: 10.1073/pnas.2000970117
PMCID:
PMC7431024
AbstractArticlePDF–2.4M
9.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
10.
Extensive rewiring of the EGFR network in colorectal cancer cells expressing transforming levels of KRASG13D
Susan A. Kennedy, Mohamed-Ali Jarboui, Sriganesh Srihari, Cinzia Raso, Kenneth Bryan, Layal Dernayka, Theodosia Charitou, Manuel Bernal-Llinares, Carlos Herrera-Montavez, Aleksandar Krstic, David Matallanas, Max Kotlyar, Igor Jurisica, Jasna Curak, Victoria Wong, Igor Stagljar, Thierry LeBihan, Lisa Imrie, Priyanka Pillai, Miriam A. Lynn, Erik Fasterius, Cristina Al-Khalili Szigyarto, James Breen, Christina Kiel, Luis Serrano, Nora Rauch, Oleksii Rukhlenko, Boris N. Kholodenko, Luis F. Iglesias-Martinez, Colm J. Ryan, Ruth Pilkington, Patrizia Cammareri, Owen Sansom, Steven Shave, Manfred Auer, Nicola Horn, Franziska Klose, Marius Ueffing, Karsten Boldt, David J. Lynn, Walter Kolch
Nat Commun. 2020; 11: 499. Published online 2020 Jan 24. doi: 10.1038/s41467-019-14224-9
PMCID:
PMC6981206
AbstractArticlePDF–3.7M
11.
Comparative gene expression profiling of in vitro differentiated megakaryocytes and erythroblasts identifies novel activatory and inhibitory platelet membrane proteins
Iain C. Macaulay, Marloes R. Tijssen, Daphne C. Thijssen-Timmer, Arief Gusnanto, Michael Steward, Philippa Burns, Cordelia F. Langford, Peter D. Ellis, Frank Dudbridge, Jaap-Jan Zwaginga, Nicholas A. Watkins, C. Ellen van der Schoot, Willem H. Ouwehand
Blood. Author manuscript; available in PMC 2019 Apr 26.
Published in final edited form as: Blood. 2007 Apr 15; 109(8): 3260–3269. Published online 2006 Dec 27. doi: 10.1182/blood-2006-07-036269
PMCID:
PMC6485507
AbstractArticlePDF–4.4M
12.
Lck promotes Zap70-dependent LAT phosphorylation by bridging Zap70 to LAT
Wan-Lin Lo, Neel H. Shah, Nagib Ahsan, Veronika Horkova, Ondrej Stepanek, Arthur R. Salomon, John Kuriyan, Arthur Weiss
Nat Immunol. Author manuscript; available in PMC 2018 Dec 18.
Published in final edited form as: Nat Immunol. 2018 Jul; 19(7): 733–741. Published online 2018 Jun 18. doi: 10.1038/s41590-018-0131-1
PMCID:
PMC6202249
AbstractArticlePDF–1.0M
13.
Plasma membrane LAT activation precedes vesicular recruitment defining two phases of early T-cell activation
Lakshmi Balagopalan, Jason Yi, Tiffany Nguyen, Katherine M. McIntire, Adam S. Harned, Kedar Narayan, Lawrence E. Samelson
Nat Commun. 2018; 9: 2013. Published online 2018 May 22. doi: 10.1038/s41467-018-04419-x
PMCID:
PMC5964120
AbstractArticlePDF–7.9M
14.
Rab6-dependent retrograde traffic of LAT controls immune synapse formation and T cell activation
Jean-Marie Carpier, Andres E. Zucchetti, Laurence Bataille, Stéphanie Dogniaux, Massiullah Shafaq-Zadah, Sabine Bardin, Marco Lucchino, Mathieu Maurin, Leonel D. Joannas, Joao Gamelas Magalhaes, Ludger Johannes, Thierry Galli, Bruno Goud, Claire Hivroz
J Exp Med. 2018 Apr 2; 215(4): 1245–1265. doi: 10.1084/jem.20162042
PMCID:
PMC5881459
AbstractArticlePDF–2.9M
15.
Dynamic Scaling Analysis of Molecular Motion within the LAT:Grb2:SOS Protein Network on Membranes
William Y.C. Huang, Han-Kuei Chiang, Jay T. Groves
Biophys J. 2017 Oct 17; 113(8): 1807–1813. Published online 2017 Oct 17. doi: 10.1016/j.bpj.2017.08.024
PMCID:
PMC5647511
AbstractArticlePDF–1.1M
16.
The Immune Signaling Adaptor LAT Contributes to the Neuroanatomical Phenotype of 16p11.2 BP2-BP3 CNVs
Maria Nicla Loviglio, Thomas Arbogast, Aia Elise Jønch, Stephan C. Collins, Konstantin Popadin, Camille S. Bonnet, Giuliana Giannuzzi, Anne M. Maillard, Sébastien Jacquemont, 16p11.2 Consortium, Binnaz Yalcin, Nicholas Katsanis, Christelle Golzio, Alexandre Reymond
Am J Hum Genet. 2017 Oct 5; 101(4): 564–577. Published online 2017 Sep 28. doi: 10.1016/j.ajhg.2017.08.016
PMCID:
PMC5630231
AbstractArticlePDF–2.1M
17.
Tonic LAT-HDAC7 signals sustain Nur77 and Irf4 expression to tune naïve CD4 T cells
Darienne R. Myers, Tannia Lau, Evan Markegard, Hyung W. Lim, Herbert Kasler, Minghua Zhu, Andrea Barczak, John P. Huizar, Julie Zikherman, David J. Erle, Weiguo Zhang, Eric Verdin, Jeroen P. Roose
Cell Rep. Author manuscript; available in PMC 2017 Sep 6.
Published in final edited form as: Cell Rep. 2017 May 23; 19(8): 1558–1571. doi: 10.1016/j.celrep.2017.04.076
PMCID:
PMC5587137
AbstractArticlePDF–979K
18.
Development of nanoscale structure in LAT-based signaling complexes
Valarie A. Barr, Eilon Sherman, Jason Yi, Itoro Akpan, Alexandre K. Rouquette-Jazdanian, Lawrence E. Samelson
J Cell Sci. 2016 Dec 15; 129(24): 4548–4562. doi: 10.1242/jcs.194886
PMCID:
PMC5201021
AbstractArticle
19.
Phosphotyrosine-mediated LAT assembly on membranes drives kinetic bifurcation in recruitment dynamics of the Ras activator SOS
William Y. C. Huang, Qingrong Yan, Wan-Chen Lin, Jean K. Chung, Scott D. Hansen, Sune M. Christensen, Hsiung-Lin Tu, John Kuriyan, Jay T. Groves
Proc Natl Acad Sci U S A. 2016 Jul 19; 113(29): 8218–8223. Published online 2016 Jul 1. doi: 10.1073/pnas.1602602113
PMCID:
PMC4961118
AbstractArticlePDF–2.1M
20.
Early onset combined immunodeficiency and autoimmunity in patients with loss-of-function mutation in LAT
Baerbel Keller, Irina Zaidman, O. Sascha Yousefi, Dov Hershkovitz, Jerry Stein, Susanne Unger, Kristina Schachtrup, Mikael Sigvardsson, Amir A. Kuperman, Avraham Shaag, Wolfgang W. Schamel, Orly Elpeleg, Klaus Warnatz, Polina Stepensky
J Exp Med. 2016 Jun 27; 213(7): 1185–1199. doi: 10.1084/jem.20151110
Correction in:
J Exp Med. 2017 Jul 3; 214(7): 2165.
PMCID:
PMC4925012
AbstractArticlePDF–2.2M

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