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Items: 1 to 20 of 139

1.
IFI16 Is Indispensable for Promoting HIF-1α-Mediated APOL1 Expression in Human Podocytes under Hypoxic Conditions
Richaundra K. Randle, Venkateswara Rao Amara, Waldemar Popik
Int J Mol Sci. 2024 Mar; 25(6): 3324. Published online 2024 Mar 15. doi: 10.3390/ijms25063324
PMCID:
PMC10970439
AbstractArticlePDF–3.3M
2.
IFI16 Induced by Direct Interaction between Esophageal Squamous Cell Carcinomas and Macrophages Promotes Tumor Progression via Secretion of IL-1α
Yuki Azumi, Yu-ichiro Koma, Shuichi Tsukamoto, Yu Kitamura, Nobuaki Ishihara, Keitaro Yamanaka, Takashi Nakanishi, Shoji Miyako, Satoshi Urakami, Kohei Tanigawa, Takayuki Kodama, Mari Nishio, Manabu Shigeoka, Yoshihiro Kakeji, Hiroshi Yokozaki
Cells. 2023 Nov; 12(22): 2603. Published online 2023 Nov 10. doi: 10.3390/cells12222603
PMCID:
PMC10670642
AbstractArticlePDF–3.6M
3.
IFI16 phase separation via multi-phosphorylation drives innate immune signaling
Dawei Liu, Krystal K Lum, Nicholas Treen, Corazón T Núñez, Jinhang Yang, Timothy R Howard, Michael Levine, Ileana M Cristea
Nucleic Acids Res. 2023 Jul 21; 51(13): 6819–6840. Published online 2023 Jun 7. doi: 10.1093/nar/gkad449
PMCID:
PMC10359621
AbstractArticlePDF–3.4M
4.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
5.
Filament assembly underpins the double-stranded DNA specificity of AIM2-like receptors
Archit Garg, Christina M Stallings, Jungsan Sohn
Nucleic Acids Res. 2023 Apr 11; 51(6): 2574–2585. Published online 2023 Mar 2. doi: 10.1093/nar/gkad090
PMCID:
PMC10085679
AbstractArticlePDF–2.5M
6.
Inflammasome genes polymorphisms are associated with progression to mechanical ventilation and death in a cohort of hospitalized COVID-19 patients in a reference hospital in Rio de Janeiro, Brazil
Milena Neira-Goulart, Nathalia Beatriz Ramos de Sá, Marcelo Ribeiro-Alves, Hugo Perazzo, Kim Mattos Geraldo, Maria Pia Diniz Ribeiro, Sandra Wagner Cardoso, Beatriz Grinsztejn, Valdiléa G. Veloso, Larissa Rodrigues Gomes, Andressa da Silva Cazote, Dalziza Victalina de Almeida, Carmem Beatriz Wagner Giacoia-Gripp, Fernanda Heloise Côrtes, Mariza Gonçalves Morgado
Gene. 2023 May 20; 865: 147325. Published online 2023 Mar 2. doi: 10.1016/j.gene.2023.147325
PMCID:
PMC9979696
AbstractArticlePDF–588K
7.
Sirt1 Negatively Regulates Cellular Antiviral Responses by Preventing the Cytoplasmic Translocation of Interferon-Inducible Protein 16 in Human Cells
Jie Wang, Xiao Qin, Yulu Huang, Ge Zhang, Yue Liu, Yuhan Cui, Yi Wang, Jinyong Pei, Shujun Ma, Zhishan Song, Xiaofei Zhu, Hui Wang, Bo Yang
J Virol. 2023 Feb; 97(2): e01975-22. Published online 2023 Feb 7. doi: 10.1128/jvi.01975-22
PMCID:
PMC9973000
AbstractArticlePDF–5.9M
8.
Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma
Yu-Fei Cao, Lei Xie, Bei-Bei Tong, Man-Yu Chu, Wen-Qi Shi, Xiang Li, Jian-Zhong He, Shao-Hong Wang, Zhi-Yong Wu, Dan-Xia Deng, Ya-Qi Zheng, Zhi-Mao Li, Xiu-E Xu, Lian-Di Liao, Yin-Wei Cheng, Li-Yan Li, Li-Yan Xu, En-Min Li
Cell Death Differ. 2023 Feb; 30(2): 527–543. Published online 2022 Dec 16. doi: 10.1038/s41418-022-01104-x
PMCID:
PMC9950447
AbstractArticlePDF–8.4M
9.
TBK1 posphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1
Jianwen Zhou, Nikoline Lander Rasmussen, Hallvard Lauritz Olsvik, Vyacheslav Akimov, Zehan Hu, Gry Evjen, Stéphanie Kaeser-Pebernard, Devanarayanan Siva Sankar, Carole Roubaty, Pauline Verlhac, Nicole van de Beek, Fulvio Reggiori, Yakubu Princely Abudu, Blagoy Blagoev, Trond Lamark, Terje Johansen, Jörn Dengjel
J Cell Biol. 2023 Feb 6; 222(2): e202108144. Published online 2022 Dec 27. doi: 10.1083/jcb.202108144
PMCID:
PMC9797988
AbstractArticlePDF–6.9M
10.
A whole genome CRISPR screen identifies AHR loss as a mechanism of resistance to a PARP7 inhibitor
Huadong Chen, Morgan E. Diolaiti, Patrick C. O’Leary, Ajda Rojc, Nevan J. Krogan, Minkyu Kim, Alan Ashworth
Mol Cancer Ther. Author manuscript; available in PMC 2023 Jan 5.
Published in final edited form as: Mol Cancer Ther. 2022 Jul 5; 21(7): 1076–1089. doi: 10.1158/1535-7163.MCT-21-0841
PMCID:
PMC9769698
AbstractArticlePDF–2.7M
11.
ARPC1B promotes mesenchymal phenotype maintenance and radiotherapy resistance by blocking TRIM21-mediated degradation of IFI16 and HuR in glioma stem cells
Zijie Gao, Jianye Xu, Yang Fan, Zongpu Zhang, Huizhi Wang, Mingyu Qian, Ping Zhang, Lin Deng, Jie Shen, Hao Xue, Rongrong Zhao, Teng Zhou, Xing Guo, Gang Li
J Exp Clin Cancer Res. 2022; 41: 323. Published online 2022 Nov 16. doi: 10.1186/s13046-022-02526-8
PMCID:
PMC9667586
AbstractArticlePDF–11M
12.
Interferon activated gene 204 (Ifi204) protects against bone loss in experimental periodontitis
Karen V Swanson, Mustafa Girnary, Tomaz Alves, Jenny PY Ting, Kimon Divaris, Jim Beck, Carolina Maschietto Pucinelli, Raquel Assed Bezerra da Silva, Dilek Uyan, Justin Wilson, William T. Seaman, Jennifer Webster-Cyriaque, Nishma Vias, Yizu Jiao, Lloyd Cantley, Arnaud Marlier, Roland R. Arnold, Julie T. Marchesan
J Periodontol. Author manuscript; available in PMC 2023 Sep 1.
Published in final edited form as: J Periodontol. 2022 Apr 11 : 10.1002/JPER.21-0668. Published online 2022 Apr 11. doi: 10.1002/JPER.21-0668
PMCID:
PMC9489626
AbstractArticlePDF–2.2M
13.
IFI16 Partners with KAP1 to Maintain Epstein-Barr Virus Latency
Huanzhou Xu, Xiaofan Li, Beth A. Rousseau, Ibukun A. Akinyemi, Tiffany R. Frey, Kevin Zhou, Lauren E. Droske, Jennifer A. Mitchell, Michael T. McIntosh, Sumita Bhaduri-McIntosh
J Virol. 2022 Sep; 96(17): e01028-22. Published online 2022 Aug 15. doi: 10.1128/jvi.01028-22
PMCID:
PMC9472614
AbstractArticlePDF–1.2M
14.
IFI16-dependent STING signaling is a crucial regulator of anti-HER2 immune response in HER2+ breast cancer
Li-Teng Ong, Wee Chyan Lee, Shijun Ma, Gokce Oguz, Zhitong Niu, Yi Bao, Mubaraka Yusuf, Puay Leng Lee, Jian Yuan Goh, Panpan Wang, Kylie Su Mei Yong, Qingfeng Chen, Wenyu Wang, Adaikalavan Ramasamy, Dave S. B. Hoon, Henrik J. Ditzel, Ern Yu Tan, Soo Chin Lee, Qiang Yu
Proc Natl Acad Sci U S A. 2022 Aug 2; 119(31): e2201376119. Published online 2022 Jul 25. doi: 10.1073/pnas.2201376119
PMCID:
PMC9351446
AbstractArticlePDF–2.4M
15.
Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer
Annamaria Salvati, Viola Melone, Assunta Sellitto, Francesca Rizzo, Roberta Tarallo, Tuula A. Nyman, Giorgio Giurato, Giovanni Nassa, Alessandro Weisz
Breast Cancer Res. 2022; 24: 52. Published online 2022 Jul 18. doi: 10.1186/s13058-022-01547-7
PMCID:
PMC9290241
AbstractArticlePDF–8.2M
16.
IFI16 Impacts Metabolic Reprogramming during Human Cytomegalovirus Infection
Gloria Griffante, Weronika Hewelt-Belka, Camilla Albano, Francesca Gugliesi, Selina Pasquero, Sergio Fernando Castillo Pacheco, Greta Bajetto, Paolo Ettore Porporato, Erica Mina, Marta Vallino, Christian Krapp, Martin Roelsgaard Jakobsen, John Purdy, Jens von Einem, Santo Landolfo, Valentina Dell’Oste, Matteo Biolatti
mBio. 2022 May-Jun; 13(3): e00435-22. Published online 2022 Apr 14. doi: 10.1128/mbio.00435-22
PMCID:
PMC9239058
AbstractArticlePDF–3.3M
17.
KSHV episome tethering sites on host chromosomes and regulation of latency-lytic switch by CHD4
Ashish Kumar, Yuanzhi Lyu, Yuichi Yanagihashi, Chanikarn Chantarasrivong, Vladimir Majerciak, Michelle Salemi, Kang-Hsin Wang, Tomoki Inagaki, Frank Chuang, Ryan R. Davis, Clifford G. Tepper, Kazushi Nakano, Chie Izumiya, Michiko Shimoda, Ken-ichi Nakajima, Alexander Merleev, Zhi-Ming Zheng, Mel Campbell, Yoshihiro Izumiya
Cell Rep. Author manuscript; available in PMC 2022 May 31.
Published in final edited form as: Cell Rep. 2022 May 10; 39(6): 110788. doi: 10.1016/j.celrep.2022.110788
PMCID:
PMC9153692
AbstractArticlePDF–3.0M
18.
The DNA sensors AIM2 and IFI16 are SLE autoantigens that bind neutrophil extracellular traps
Brendan Antiochos, Daniela Trejo-Zambrano, Paride Fenaroli, Avi Rosenberg, Alan Baer, Archit Garg, Jungsan Sohn, Jessica Li, Michelle Petri, Daniel W Goldman, Christopher Mecoli, Livia Casciola-Rosen, Antony Rosen
eLife. 2022; 11: e72103. Published online 2022 May 24. doi: 10.7554/eLife.72103
PMCID:
PMC9129876
AbstractArticlePDF–5.0M
19.
Type I IFN stimulates IFI16-mediated aromatase expression in adipocytes that promotes E2-dependent growth of ER-positive breast cancer
Na-Lee Ka, Ga Young Lim, Seung‑Su Kim, Sewon Hwang, Juhyeong Han, Yun-Hee Lee, Mi-Ock Lee
Cell Mol Life Sci. 2022 Jun; 79(6): 306. Published online 2022 May 20. doi: 10.1007/s00018-022-04333-y
PMCID:
PMC9122892
AbstractArticlePDF–11M
20.
IFI16 induces inflammation in hepatitis B virus-associated glomerulonephritis by regulating the Caspase-1/ IL-1 ß pathway
Li Liu, Shuangshuang Xie, Cheng Li, Yue Guo, Xiaoyan Liu, Xiuhua Zhao, Qiang Li, Wenjun Du
Diagn Pathol. 2022; 17: 39. Published online 2022 Apr 23. doi: 10.1186/s13000-022-01220-9
PMCID:
PMC9034479
AbstractArticlePDF–1.7M

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