PMC Links for GEO Profiles (Select 108251000) - PMC

Janina Sörmann, Marcus Schewe, Peter Proks, Thibault Jouen-Tachoire, Shanlin Rao, Elena B. Riel, Katherine E. Agre, Amber Begtrup, John Dean, Maria Descartes, Jan Fischer, Alice Gardham, Carrie Lahner, Paul R. Mark, Srikanth Muppidi, Pavel N. Pichurin, Joseph Porrmann, Jens Schallner, Kirstin Smith, Volker Straub, Pradeep Vasudevan, Rebecca Willaert, Elisabeth P. Carpenter, Karin E. J. Rödström, Michael G. Hahn, Thomas Müller, Thomas Baukrowitz, Matthew E. Hurles, Caroline F. Wright, Stephen J. Tucker

Nat Genet. 2022; 54(10): 1534–1543. Published online 2022 Oct 4. doi: 10.1038/s41588-022-01185-x

PMCID:: PMC9534757

Abstract Article PDF–4.4M

Select item 90754204.

MicroRNAs Regulate TASK‐1 and Are Linked to Myocardial Dilatation in Atrial Fibrillation

Felix Wiedmann, Manuel Kraft, Stefan Kallenberger, Antonius Büscher, Amelie Paasche, Pablo L. Blochberger, Timon Seeger, Natasa Jávorszky, Gregor Warnecke, Rawa Arif, Jamila Kremer, Matthias Karck, Norbert Frey, Constanze Schmidt

J Am Heart Assoc. 2022 Apr 5; 11(7): e023472. Published online 2022 Mar 18. doi: 10.1161/JAHA.121.023472

PMCID:: PMC9075420

Abstract Article PDF–2.5M

Select item 87448095.

Expression of Proton-Sensitive GPR31, GPR151, TASK1 and TASK3 in Common Skin Tumors

Antonia Förch, Susanne Wallner, Florian Zeman, Tobias Ettl, Christoph Brochhausen, Stephan Schreml

Cells. 2022 Jan; 11(1): 27. Published online 2021 Dec 23. doi: 10.3390/cells11010027

PMCID:: PMC8744809

Abstract Article PDF–2.5M

Select item 83217926.

Human adrenal glomerulosa cells express K2P and GIRK potassium channels that are inhibited by ANG II and ACTH

John J. Enyeart, Judith A. Enyeart

Am J Physiol Cell Physiol. 2021 Jul 1; 321(1): C158–C175. Published online 2021 May 26. doi: 10.1152/ajpcell.00118.2021

PMCID:: PMC8321792

Abstract Article

Select item 81260117.

KCNK3 Mutation Causes Altered Immune Function in Pulmonary Arterial Hypertension Patients and Mouse Models

James D. West, Eric D. Austin, Elise M. Rizzi, Ling Yan, Harikrishna Tanjore, Amber L. Crabtree, Christy S. Moore, Gladson Muthian, Erica J. Carrier, David A. Jacobson, Rizwan Hamid, Peggy L. Kendall, Susan Majka, Anandharajan Rathinasabapathy

Int J Mol Sci. 2021 May; 22(9): 5014. Published online 2021 May 9. doi: 10.3390/ijms22095014

PMCID:: PMC8126011

Abstract Article PDF–4.7M

Select item 70038468.

Effects of the ventilatory stimulant, doxapram on human TASK‐3 (KCNK9, K2P9.1) channels and TASK‐1 (KCNK3, K2P3.1) channels

Kevin P. Cunningham, D. Euan MacIntyre, Alistair Mathie, Emma L. Veale

Acta Physiol (Oxf) 2020 Feb; 228(2): e13361. Published online 2019 Sep 18. doi: 10.1111/apha.13361

PMCID:: PMC7003846

Abstract Article PDF–1.2M

Select item 67937859.

Genetic variants of rs1275988 and rs2586886 in TWIK-related acid-sensitive K⁺ channel-1 gene may be potential risk factors for obese patients with obstructive sleep apnea

Tian Shi, Xiao-Guang Yao, Mei Li, Mulalibieke Heizhati, Xiu-Fang Li, Lu Wen, Yuan-Yuan He, Ling Yao, Ying-Chun Wang, Jing Hong, Nan-Fang Li

Chin Med J (Engl) 2019 Sep 5; 132(17): 2059–2065. Published online 2019 Sep 5. doi: 10.1097/CM9.0000000000000401

PMCID:: PMC6793785

Abstract Article PDF–185K

Select item 639108010.

The molecular basis for an allosteric inhibition of K⁺-flux gating in K_2P channels

Susanne Rinné, Aytug K Kiper, Kirsty S Vowinkel, David Ramírez, Marcus Schewe, Mauricio Bedoya, Diana Aser, Isabella Gensler, Michael F Netter, Phillip J Stansfeld, Thomas Baukrowitz, Wendy Gonzalez, Niels Decher

eLife. 2019; 8: e39476. Published online 2019 Feb 26. doi: 10.7554/eLife.39476

PMCID:: PMC6391080

Abstract Article PDF–3.3M

Select item 637607411.

Characterization and regulation of wild‐type and mutant TASK‐1 two pore domain potassium channels indicated in pulmonary arterial hypertension

Kevin P. Cunningham, Robyn G. Holden, Pilar M. Escribano‐Subias, Angel Cogolludo, Emma L. Veale, Alistair Mathie

J Physiol. 2019 Feb 15; 597(4): 1087–1101. Published online 2018 Nov 24. doi: 10.1113/JP277275

PMCID:: PMC6376074

Abstract Article PDF–1.8M

Select item 616668212.

Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei

Domenico Fasci, Hugo van Ingen, Richard A. Scheltema, Albert J. R. Heck

Mol Cell Proteomics. 2018 Oct; 17(10): 2018–2033. Published online 2018 Jul 18. doi: 10.1074/mcp.RA118.000924

PMCID:: PMC6166682

Abstract Article PDF–3.8M

Select item 578352213.

MicroRNA-138 promotes proliferation and suppresses mitochondrial depolarization in human pulmonary artery smooth muscle cells through targeting TASK-1

Jin-Jun Liu, Heng Zhang, Fang Xing, Bi Tang, Shi-Li Wu, Ling Xuan, Pin-Fang Kang, Qiong Xu, Hong-Ju Wang, Ning-Ru Zhang, Xiao-Jing Wang

Mol Med Rep. 2018 Feb; 17(2): 3021–3027. Published online 2017 Dec 6. doi: 10.3892/mmr.2017.8200

PMCID:: PMC5783522

Abstract Article PDF–1.1M

Select item 563462914.

Heterodimerization of two pore domain K⁺ channel TASK1 and TALK2 in living heterologous expression systems

Yoshiaki Suzuki, Kanako Tsutsumi, Tatsuya Miyamoto, Hisao Yamamura, Yuji Imaizumi

PLoS One. 2017; 12(10): e0186252. Published online 2017 Oct 10. doi: 10.1371/journal.pone.0186252

PMCID:: PMC5634629

Abstract Article PDF–2.3M

Select item 563429315.

The Impact of Heterozygous KCNK3 Mutations Associated With Pulmonary Arterial Hypertension on Channel Function and Pharmacological Recovery

Michael S. Bohnen, Danilo Roman‐Campos, Cecile Terrenoire, Jack Jnani, Kevin J. Sampson, Wendy K. Chung, Robert S. Kass

J Am Heart Assoc. 2017 Sep; 6(9): e006465. Published online 2017 Sep 9. doi: 10.1161/JAHA.117.006465

PMCID:: PMC5634293

Abstract Article PDF–2.9M

Select item 538397316.

A burden of rare variants in BMPR2 and KCNK3 contributes to a risk of familial pulmonary arterial hypertension

Koichiro Higasa, Aiko Ogawa, Chikashi Terao, Masakazu Shimizu, Shinji Kosugi, Ryo Yamada, Hiroshi Date, Hiromi Matsubara, Fumihiko Matsuda

BMC Pulm Med. 2017; 17: 57. Published online 2017 Apr 7. doi: 10.1186/s12890-017-0400-z

PMCID:: PMC5383973

Abstract Article PDF–507K

Select item 494543017.

KCNK3 VARIANTS ARE ASSOCIATED WITH HYPERALDOSTERONISM AND HYPERTENSION

Ani Manichaikul, Stephen S. Rich, Matthew A. Allison, Nick A. Guagliardo, Douglas A. Bayliss, Robert M. Carey, Paula Q. Barrett

Hypertension. Author manuscript; available in PMC 2017 Aug 1.

Published in final edited form as: Hypertension. 2016 Aug; 68(2): 356–364. Published online 2016 Jun 13. doi: 10.1161/HYPERTENSIONAHA.116.07564

PMCID:: PMC4945430

Abstract Article PDF–307K

Select item 490562618.

TASK-1 Regulates Apoptosis and Proliferation in a Subset of Non-Small Cell Lung Cancers

Katharina Leithner, Birgit Hirschmugl, Yingji Li, Bi Tang, Rita Papp, Chandran Nagaraj, Elvira Stacher, Philipp Stiegler, Jörg Lindenmann, Andrea Olschewski, Horst Olschewski, Andelko Hrzenjak

PLoS One. 2016; 11(6): e0157453. Published online 2016 Jun 13. doi: 10.1371/journal.pone.0157453

PMCID:: PMC4905626

Abstract Article PDF–1.9M

Select item 476037519.

A dual phosphorylation switch controls 14-3-3-dependent cell surface expression of TASK-1

Markus Kilisch, Olga Lytovchenko, Eric C. Arakel, Daniela Bertinetti, Blanche Schwappach

J Cell Sci. 2016 Feb 15; 129(4): 831–842. doi: 10.1242/jcs.180182

PMCID:: PMC4760375

Abstract Article

Select item 472624620.

Functional mutagenesis screens reveal the ‘cap structure’ formation in disulfide-bridge free TASK channels

Matthias Goldstein, Susanne Rinné, Aytug K. Kiper, David Ramírez, Michael F. Netter, Daniel Bustos, Beatriz Ortiz-Bonnin, Wendy González, Niels Decher

Sci Rep. 2016; 6: 19492. Published online 2016 Jan 22. doi: 10.1038/srep19492

PMCID:: PMC4726246

Abstract Article PDF–2.2M

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