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Select item 90325221.

Cysteine-Rich LIM-Only Protein 4 (CRP4) Promotes Atherogenesis in the ApoE^−/− Mouse Model

Natalie Längst, Julia Adler, Anna Kuret, Andreas Peter, Peter Ruth, Karsten Boldt, Robert Lukowski

Cells. 2022 Apr; 11(8): 1364. Published online 2022 Apr 17. doi: 10.3390/cells11081364

PMCID:: PMC9032522

Abstract Article PDF–5.4M

Select item 88944892.

Changes to gut amino acid transporters and microbiome associated with increased E/I ratio in Chd8^+/− mouse model of ASD-like behavior

You Yu, Bing Zhang, Peifeng Ji, Zhenqiang Zuo, Yongxi Huang, Ning Wang, Chang Liu, Shuang-Jiang Liu, Fangqing Zhao

Nat Commun. 2022; 13: 1151. Published online 2022 Mar 3. doi: 10.1038/s41467-022-28746-2

PMCID:: PMC8894489

Abstract Article PDF–3.1M

Select item 85706913.

IFN-γ mediates Paneth cell death via suppression of mTOR

Alessandra Araujo, Alexandra Safronova, Elise Burger, Américo López-Yglesias, Shilpi Giri, Ellie T Camanzo, Andrew T Martin, Sergei Grivennikov, Felix Yarovinsky

eLife. 2021; 10: e60478. Published online 2021 Oct 11. doi: 10.7554/eLife.60478

PMCID:: PMC8570691

Abstract Article PDF–14M

Select item 81924974.

Western Diet Induces Paneth Cell Defects through Microbiome Alterations and Farnesoid X Receptor and Type I Interferon Activation

Ta-Chiang Liu, Justin T. Kern, Umang Jain, Naomi M. Sonnek, Shanshan Xiong, Katherine F. Simpson, Kelli L. VanDussen, Emma S. Winkler, Talin Haritunians, Atika Malique, Qiuhe Lu, Yo Sasaki, Chad Storer, Michael S. Diamond, Richard D. Head, Dermot P.B. McGovern, Thaddeus S. Stappenbeck

Cell Host Microbe. Author manuscript; available in PMC 2022 Jun 9.

Published in final edited form as: Cell Host Microbe. 2021 Jun 9; 29(6): 988–1001.e6. Published online 2021 May 18. doi: 10.1016/j.chom.2021.04.004

PMCID:: PMC8192497

Abstract Article PDF–1.9M

Select item 77727745.

Paneth cell–derived growth factors support tumorigenesis in the small intestine

Qing Chen, Kohei Suzuki, Luis Sifuentes-Dominguez, Naoteru Miyata, Jie Song, Adam Lopez, Petro Starokadomskyy, Purva Gopal, Igor Dozmorov, Shuai Tan, Bujun Ge, Ezra Burstein

Life Sci Alliance. 2021 Mar; 4(3): e202000934. Published online 2020 Dec 28. doi: 10.26508/lsa.202000934

PMCID:: PMC7772774

Abstract Article PDF–3.1M

Select item 73329816.

LGR5 controls extracellular matrix production by stem cells in the developing intestine

Valeria Fernandez Vallone, Morgane Leprovots, Didac Ribatallada‐Soriano, Romain Gerbier, Anne Lefort, Frédérick Libert, Gilbert Vassart, Marie‐Isabelle Garcia

EMBO Rep. 2020 Jul 3; 21(7): e49224. Published online 2020 May 28. doi: 10.15252/embr.201949224

PMCID:: PMC7332981

Abstract Article PDF–7.1M

Select item 61794457.

Loss of Paneth cell autophagy causes acute susceptibility to Toxoplasma gondii-mediated inflammation

Elise Burger, Alessandra Araujo, Américo López-Yglesias, Michael W. Rajala, Linda Geng, Beth Levine, Lora V. Hooper, Ezra Burstein, Felix Yarovinsky

Cell Host Microbe. Author manuscript; available in PMC 2019 Feb 14.

Published in final edited form as: Cell Host Microbe. 2018 Feb 14; 23(2): 177–190.e4. Published online 2018 Jan 18. doi: 10.1016/j.chom.2018.01.001

PMCID:: PMC6179445

Abstract Article PDF–1.1M

Select item 44837698.

Rab8a vesicles regulate Wnt ligand delivery and Paneth cell maturation at the intestinal stem cell niche

Soumyashree Das, Shiyan Yu, Ryotaro Sakamori, Pavan Vedula, Qiang Feng, Juan Flores, Andrew Hoffman, Jiang Fu, Ewa Stypulkowski, Alexis Rodriguez, Radek Dobrowolski, Akihiro Harada, Wei Hsu, Edward M. Bonder, Michael P. Verzi, Nan Gao

Development. 2015 Jun 15; 142(12): 2147–2162. doi: 10.1242/dev.121046

PMCID:: PMC4483769

Abstract Article

Select item 32368169.

Biosynthesis and antimicrobial evaluation of backbone-cyclized alpha-defensins^#

Angie E. Garcia, Kenneth P. Tai, Shadakshara S. Puttamadappa, Alexander Shekhtman, Andre J. Ouellette, Julio A. Camarero

Biochemistry. Author manuscript; available in PMC 2012 Dec 6.

Published in final edited form as: Biochemistry. 2011 Dec 6; 50(48): 10508–10519. Published online 2011 Nov 9. doi: 10.1021/bi201430f

PMCID:: PMC3236816

Abstract Article PDF–1.9M

Select item 317805910.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 312827311.

Lgr4 is required for Paneth cell differentiation and maintenance of intestinal stem cells ex vivo

Roxana C Mustata, Tom Van Loy, Anne Lefort, Frédérick Libert, Sandra Strollo, Gilbert Vassart, Marie-Isabelle Garcia

EMBO Rep. 2011 Jun; 12(6): 558–564. Published online 2011 Apr 21. doi: 10.1038/embor.2011.52

PMCID:: PMC3128273

Abstract Article PDF–1.5M

Select item 301990612.

Strain-Specific Polymorphisms in Paneth Cell α-Defensins of C57BL/6 Mice and Evidence of Vestigial Myeloid α-Defensin Pseudogenes

Michael T. Shanahan, Hiroki Tanabe, André J. Ouellette

Infect Immun. 2011 Jan; 79(1): 459–473. Published online 2010 Nov 1. doi: 10.1128/IAI.00996-10

PMCID:: PMC3019906

Abstract Article PDF–4.3M

Select item 284419713.

Elevated Expression of Paneth Cell CRS4C in Ileitis-prone SAMP1/YitFc Mice: REGIONAL DISTRIBUTION, SUBCELLULAR LOCALIZATION, AND MECHANISM OF ACTION

Michael T. Shanahan, Alda Vidrich, Yoshinori Shirafuji, Claire L. Dubois, Agnes Henschen-Edman, Susan J. Hagen, Steven M. Cohn, André J. Ouellette

J Biol Chem. 2010 Mar 5; 285(10): 7493–7504. Published online 2010 Jan 7. doi: 10.1074/jbc.M109.083220

PMCID:: PMC2844197

Abstract Article PDF–1.9M

Select item 280744114.

Manual annotation and analysis of the defensin gene cluster in the C57BL/6J mouse reference genome

Clara Amid, Linda M Rehaume, Kelly L Brown, James GR Gilbert, Gordon Dougan, Robert EW Hancock, Jennifer L Harrow

BMC Genomics. 2009; 10: 606. Published online 2009 Dec 15. doi: 10.1186/1471-2164-10-606

PMCID:: PMC2807441

Abstract Article PDF–477K

Select item 279579615.

Enteric defensins are essential regulators of intestinal microbial ecology

Nita H. Salzman, Kuiechun Hung, Dipica Haribhai, Hiutung Chu, Jenny Karlsson-Sjöberg, Elad Amir, Paul Teggatz, Melissa Barman, Michael Hayward, Daniel Eastwood, Maaike Stoel, Yanjiao Zhou, Erica Sodergren, George M. Weinstock, Charles L. Bevins, Calvin B. Williams, Nicolaas A. Bos

Nat Immunol. Author manuscript; available in PMC 2010 Jul 1.

Published in final edited form as: Nat Immunol. 2010 Jan; 11(1): 76–83. Published online 2009 Oct 22. doi: 10.1038/ni.1825