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Select item 106824151.

Cross-species epigenetic regulation of nucleus accumbens KCNN3 transcripts by excessive ethanol drinking

Patrick J. Mulholland, Audrey E. Padula, Larry J. Wilhelm, Byung Park, Kathleen A. Grant, Betsy M. Ferguson, Rita Cervera-Juanes

Transl Psychiatry. 2023; 13: 364. Published online 2023 Nov 27. doi: 10.1038/s41398-023-02676-z

PMCID:: PMC10682415

Abstract Article PDF–2.1M

Select item 99463522.

Asprosin promotes feeding through SK channel–dependent activation of AgRP neurons

Bing Feng, Hesong Liu, Ila Mishra, Clemens Duerrschmid, Peiyu Gao, Pingwen Xu, Chunmei Wang, Yanlin He

Sci Adv. 2023 Feb; 9(8): eabq6718. Published online 2023 Feb 22. doi: 10.1126/sciadv.abq6718

PMCID:: PMC9946352

Abstract Article PDF–1.8M

Select item 83132393.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 76996204.

Bioinformatics identification and pharmacological validation of Kcnn3/K_Ca2 channels as a mediator of negative affective behaviors and excessive alcohol drinking in mice

Audrey E. Padula, Jennifer A. Rinker, Marcelo F. Lopez, Megan K. Mulligan, Robert W. Williams, Howard C. Becker, Patrick J. Mulholland

Transl Psychiatry. 2020; 10: 414. Published online 2020 Nov 27. doi: 10.1038/s41398-020-01099-4

PMCID:: PMC7699620

Abstract Article PDF–1.4M

Select item 72128055.

Conditional Single Vector CRISPR/SaCas9 Viruses for Efficient Mutagenesis in the Adult Mouse Nervous System

Avery C. Hunker, Marta E. Soden, Dasha Krayushkina, Gabriel Heymann, Rajeshwar Awatramani, Larry S. Zweifel

Cell Rep. Author manuscript; available in PMC 2020 May 11.

Published in final edited form as: Cell Rep. 2020 Mar 24; 30(12): 4303–4316.e6. doi: 10.1016/j.celrep.2020.02.092

PMCID:: PMC7212805

Abstract Article PDF–2.6M

Select item 63369976.

Caveolae facilitate TRPV4-mediated Ca²⁺ signaling and the hierarchical activation of Ca²⁺-activated K⁺ channels in K⁺-secreting renal collecting duct cells

Yue Li, Hongxiang Hu, Roger G. O’Neil

Am J Physiol Renal Physiol. 2018 Dec 1; 315(6): F1626–F1636. Published online 2018 Sep 12. doi: 10.1152/ajprenal.00076.2018

PMCID:: PMC6336997

Abstract Article

Select item 62489077.

A Small Potassium Current in AgRP/NPY Neurons Regulates Feeding Behavior and Energy Metabolism

Yanlin He, Gang Shu, Yongjie Yang, Pingwen Xu, Yan Xia, Chunmei Wang, Kenji Saito, Antentor Hinton, Jr., Xiaofeng Yan, Chen Liu, Qi Wu, Qingchun Tong, Yong Xu

Cell Rep. Author manuscript; available in PMC 2018 Nov 21.

Published in final edited form as: Cell Rep. 2016 Nov 8; 17(7): 1807–1818. doi: 10.1016/j.celrep.2016.10.044

PMCID:: PMC6248907

Abstract Article PDF–1.6M

Select item 56130128.

Premature contractions of the bladder are suppressed by interactions between TRPV4 and SK3 channels in murine detrusor PDGFRα⁺ cells

Haeyeong Lee, Byoung H. Koh, Lauren E. Peri, Robert D. Corrigan, Hyun-Tai Lee, Nikita E. George, Bhupal P. Bhetwal, Yeming Xie, Brian A. Perrino, Toby C. Chai, Kenton M. Sanders, Sang Don Koh

Sci Rep. 2017; 7: 12245. Published online 2017 Sep 25. doi: 10.1038/s41598-017-12561-7

PMCID:: PMC5613012

Abstract Article PDF–3.7M

Select item 54958819.

Dynamic coupling between TRPV4 and Ca²⁺-activated SK1/3 and IK1 K⁺ channels plays a critical role in regulating the K⁺-secretory BK channel in kidney collecting duct cells

Yue Li, Hongxiang Hu, Jin-Bin Tian, Michael X. Zhu, Roger G. O’Neil

Am J Physiol Renal Physiol. 2017 Jun 1; 312(6): F1081–F1089. Published online 2017 Mar 8. doi: 10.1152/ajprenal.00037.2017

PMCID:: PMC5495881

Abstract Article

Select item 547658810.

Down-regulation of K_Ca2.3 channels causes erectile dysfunction in mice

Simon Comerma-Steffensen, Attila Kun, Elise R. Hedegaard, Susie Mogensen, Christian Aalkjaer, Ralf Köhler, Birgitte Mønster Christensen, Ulf Simonsen

Sci Rep. 2017; 7: 3839. Published online 2017 Jun 19. doi: 10.1038/s41598-017-04188-5

PMCID:: PMC5476588

Abstract Article PDF–2.7M

Select item 511988511.

Chronic social isolation reduces 5-HT neuronal activity via upregulated SK3 calcium-activated potassium channels

Derya Sargin, David K Oliver, Evelyn K Lambe

eLife. 2016; 5: e21416. Published online 2016 Nov 22. doi: 10.7554/eLife.21416

PMCID:: PMC5119885

Abstract Article PDF–1.6M

Select item 486738812.

Endothelial SK3 channel-associated Ca²⁺ microdomains modulate blood pressure

Fui C. Yap, David S. Weber, Mark S. Taylor, Mary I. Townsley, Brian S. Comer, James Maylie, John P. Adelman, Mike T. Lin

Am J Physiol Heart Circ Physiol. 2016 May 1; 310(9): H1151–H1163. Published online 2016 Mar 4. doi: 10.1152/ajpheart.00787.2015

PMCID:: PMC4867388

Abstract Article

Select item 483951613.

KCNN Genes that Encode Small-Conductance Ca²⁺-Activated K⁺ Channels Influence Alcohol and Drug Addiction

Audrey E Padula, William C Griffin, III, Marcelo F Lopez, Sudarat Nimitvilai, Reginald Cannady, Natalie S McGuier, Elissa J Chesler, Michael F Miles, Robert W Williams, Patrick K Randall, John J Woodward, Howard C Becker, Patrick J Mulholland

Neuropsychopharmacology. 2015 Jul; 40(8): 1928–1939. Prepublished online 2015 Feb 9. Published online 2015 Mar 4. doi: 10.1038/npp.2015.42

PMCID:: PMC4839516

Abstract Article PDF–704K

Select item 437073614.

Ion Channel Expression in the Developing Enteric Nervous System

Caroline S. Hirst, Jaime P. P. Foong, Lincon A. Stamp, Emily Fegan, Stephan Dent, Edward C. Cooper, Alan E. Lomax, Colin R. Anderson, Joel C. Bornstein, Heather M. Young, Sonja J. McKeown

PLoS One. 2015; 10(3): e0123436. Published online 2015 Mar 23. doi: 10.1371/journal.pone.0123436