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Items: 1 to 20 of 76

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Electric field stimulation unmasks a subtle role for T-type calcium channels in regulating lymphatic contraction
Michael J. Davis, Jorge A. Castorena-Gonzalez, Scott D. Zawieja
Sci Rep. 2023; 13: 15862. Published online 2023 Sep 22. doi: 10.1038/s41598-023-42877-6
PMCID:
PMC10516884
AbstractArticlePDF–1.7M
3.
CaV3.1 T-type calcium channels are important for spatial memory processing in the dorsal subiculum
Srdjan M. Joksimovic, Seyed Mohammadreza Ghodsi, Jasper A. Heinsbroek, James E. Orfila, Nicolas Busquet, Vesna Tesic, Robert Valdez, Brier Fine-Raquet, Vesna Jevtovic-Todorovic, Yogendra H. Raol, Paco S. Herson, Slobodan M. Todorovic
Neuropharmacology. Author manuscript; available in PMC 2024 Mar 15.
Published in final edited form as: Neuropharmacology. 2023 Mar 15; 226: 109400. Published online 2022 Dec 29. doi: 10.1016/j.neuropharm.2022.109400
PMCID:
PMC9898223
AbstractArticlePDF–2.1M
4.
Loss of zinc-finger protein 212 leads to Purkinje cell death and locomotive abnormalities with phospholipase D3 downregulation
Rin Khang, Areum Jo, Hojin Kang, Hanna Kim, Eunsang Kwag, Ji-Yeong Lee, Okjae Koo, Jinsu Park, Hark Kyun Kim, Dong-Gyu Jo, Inwoo Hwang, Jee-Yin Ahn, Yunjong Lee, Jeong-Yun Choi, Yun-Song Lee, Joo-Ho Shin
Sci Rep. 2021; 11: 22745. Published online 2021 Nov 23. doi: 10.1038/s41598-021-02218-x
PMCID:
PMC8610974
AbstractArticlePDF–2.5M
5.
Homeostatic plasticity and burst activity are mediated by hyperpolarization-activated cation currents and T-type calcium channels in neuronal cultures
Anikó Rátkai, Krisztián Tárnok, Hajar El Aouad, Brigitta Micska, Katalin Schlett, Attila Szücs
Sci Rep. 2021; 11: 3236. Published online 2021 Feb 5. doi: 10.1038/s41598-021-82775-3
PMCID:
PMC7864958
AbstractArticlePDF–5.4M
6.
QKI is a critical pre-mRNA alternative splicing regulator of cardiac myofibrillogenesis and contractile function
Xinyun Chen, Ying Liu, Chen Xu, Lina Ba, Zhuo Liu, Xiuya Li, Jie Huang, Ed Simpson, Hongyu Gao, Dayan Cao, Wei Sheng, Hanping Qi, Hongrui Ji, Maria Sanderson, Chen-Leng Cai, Xiaohui Li, Lei Yang, Jie Na, Kenichi Yamamura, Yunlong Liu, Guoying Huang, Weinian Shou, Ning Sun
Nat Commun. 2021; 12: 89. Published online 2021 Jan 4. doi: 10.1038/s41467-020-20327-5
PMCID:
PMC7782589
AbstractArticlePDF–8.6M
7.
Global genetic deletion of CaV3.3 channels facilitates anaesthetic induction and enhances isoflurane-sparing effects of T-type calcium channel blockers
Simon Feseha, Tamara Timic Stamenic, Damon Wallace, Caesare Tamag, Lingling Yang, Jen Q. Pan, Slobodan M. Todorovic
Sci Rep. 2020; 10: 21510. Published online 2020 Dec 9. doi: 10.1038/s41598-020-78488-8
PMCID:
PMC7725806
AbstractArticlePDF–4.4M
8.
Concomitant genetic ablation of L-type Cav1.3 (α1D) and T-type Cav3.1 (α1G) Ca2+ channels disrupts heart automaticity
Matthias Baudot, Eleonora Torre, Isabelle Bidaud, Julien Louradour, Angelo G. Torrente, Lucile Fossier, Leïla Talssi, Joël Nargeot, Stéphanie Barrère-Lemaire, Pietro Mesirca, Matteo E. Mangoni
Sci Rep. 2020; 10: 18906. Published online 2020 Nov 3. doi: 10.1038/s41598-020-76049-7
PMCID:
PMC7642305
AbstractArticlePDF–12M
9.
TCF7L2 regulates postmitotic differentiation programmes and excitability patterns in the thalamus
Marcin Andrzej Lipiec, Joanna Bem, Kamil Koziński, Chaitali Chakraborty, Joanna Urban-Ciećko, Tomasz Zajkowski, Michał Dąbrowski, Łukasz Mateusz Szewczyk, Angel Toval, José Luis Ferran, Andrzej Nagalski, Marta Barbara Wiśniewska
Development. 2020 Aug 15; 147(16): dev190181. Published online 2020 Aug 25. doi: 10.1242/dev.190181
PMCID:
PMC7473649
AbstractArticle
10.
T-box transcription factor 3 governs a transcriptional program for the function of the mouse atrioventricular conduction system
Rajiv A. Mohan, Fernanda M. Bosada, Jan H. van Weerd, Karel van Duijvenboden, Jianan Wang, Mathilda T. M. Mommersteeg, Ingeborg B. Hooijkaas, Vincent Wakker, Corrie de Gier-de Vries, Ruben Coronel, Gerard J. J. Boink, Jeroen Bakkers, Phil Barnett, Bas J. Boukens, Vincent M. Christoffels
Proc Natl Acad Sci U S A. 2020 Aug 4; 117(31): 18617–18626. Published online 2020 Jul 16. doi: 10.1073/pnas.1919379117
PMCID:
PMC7414162
AbstractArticlePDF–1.7M
11.
Trait-associated noncoding variant regions affect TBX3 regulation and cardiac conduction
Jan Hendrik van Weerd, Rajiv A Mohan, Karel van Duijvenboden, Ingeborg B Hooijkaas, Vincent Wakker, Bastiaan J Boukens, Phil Barnett, Vincent M Christoffels
eLife. 2020; 9: e56697. Published online 2020 Jul 16. doi: 10.7554/eLife.56697
PMCID:
PMC7365664
AbstractArticlePDF–1.8M
12.
Inhibition of G protein-gated K+ channels by tertiapin-Q rescues sinus node dysfunction and atrioventricular conduction in mouse models of primary bradycardia
Isabelle Bidaud, Antony Chung You Chong, Agnes Carcouet, Stephan De Waard, Flavien Charpentier, Michel Ronjat, Michel De Waard, Dirk Isbrandt, Kevin Wickman, Anne Vincent, Matteo E. Mangoni, Pietro Mesirca
Sci Rep. 2020; 10: 9835. Published online 2020 Jun 17. doi: 10.1038/s41598-020-66673-8
PMCID:
PMC7300035
AbstractArticlePDF–1.8M
13.
A missense mutation of ErbB2 produces a novel mouse model of stillbirth associated with a cardiac abnormality but lacking abnormalities of placental structure
Heba Shawer, Esther Aiyelaagbe, Christopher Clowes, Samantha C. Lean, Yinhui Lu, Karl E. Kadler, Alan Kerby, Mark R. Dilworth, Kathryn E. Hentges, Alexander E. P. Heazell
PLoS One. 2020; 15(6): e0233007. Published online 2020 Jun 3. doi: 10.1371/journal.pone.0233007
PMCID:
PMC7269201
AbstractArticlePDF–3.0M
14.
Ecm29-mediated proteasomal distribution modulates excitatory GABA responses in the developing brain
Min Lee, Yen-Chen Liu, Chen Chen, Chi-Huan Lu, Shao-Tzu Lu, Tzyy-Nan Huang, Meng-Tsung Hsu, Yi-Ping Hsueh, Pei-Lin Cheng
J Cell Biol. 2020 Feb 3; 219(2): e201903033. Published online 2020 Jan 7. doi: 10.1083/jcb.201903033
PMCID:
PMC7041676
AbstractArticlePDF–5.4M
15.
T-type, but not L-type, voltage-gated calcium channels are dispensable for lymphatic pacemaking and spontaneous contractions
Kim H. T. To, Peichun Gui, Min Li, Scott D. Zawieja, Jorge A. Castorena-Gonzalez, Michael J. Davis
Sci Rep. 2020; 10: 70. Published online 2020 Jan 9. doi: 10.1038/s41598-019-56953-3
PMCID:
PMC6952455
AbstractArticlePDF–4.3M
16.
Adult loss of Cacna1a in mice recapitulates childhood absence epilepsy by distinct thalamic bursting mechanisms
Qing-Long Miao, Stefan Herlitze, Melanie D Mark, Jeffrey L Noebels
Brain. 2020 Jan; 143(1): 161–174. Published online 2019 Dec 4. doi: 10.1093/brain/awz365
Correction in:
Brain. 2020 Mar; 143(3): e24.
PMCID:
PMC6935748
AbstractArticlePDF–1.4M
17.
Alterations in Oscillatory Behavior of Central Medial Thalamic Neurons Demonstrate a Key Role of CaV3.1 Isoform of T-Channels During Isoflurane-Induced Anesthesia
Tamara Timic Stamenic, Simon Feseha, Robert Valdez, Wanzhu Zhao, Jost Klawitter, Slobodan M Todorovic
Cereb Cortex. 2019 Dec; 29(11): 4679–4696. Published online 2019 Jan 31. doi: 10.1093/cercor/bhz002
PMCID:
PMC6917523
AbstractArticlePDF–1.7M
18.
Low voltage-activated CaV3.1 calcium channels in T cells: A role in shaping the immune response
Huiyun Wang, Xuexin Zhang, Li Xue, Juan Xing, Marie-Hélène Jouvin, James W. Putney, Matthew P. Anderson, Mohamed Trebak, Jean-Pierre Kinet
Immunity. Author manuscript; available in PMC 2019 Oct 1.
Published in final edited form as: Immunity. 2016 Apr 19; 44(4): 782–794. Published online 2016 Mar 29. doi: 10.1016/j.immuni.2016.01.015
PMCID:
PMC6771933
AbstractArticlePDF–2.3M
19.
Role of the α1G T-Type Calcium Channel in Spontaneous Absence Seizures in Mutant Mice
Inseon Song, Daesoo Kim, Soonwook Choi, Minjeong Sun, Yeongin Kim, Hee-Sup Shin
J Neurosci. 2004 Jun 2; 24(22): 5249–5257. doi: 10.1523/JNEUROSCI.5546-03.2004
PMCID:
PMC6729205
AbstractArticlePDF–462K
20.
Functional Coupling between mGluR1 and Cav3.1 T-Type Calcium Channels Contributes to Parallel Fiber-Induced Fast Calcium Signaling within Purkinje Cell Dendritic Spines
Michael E. Hildebrand, Philippe Isope, Taisuke Miyazaki, Toshitaka Nakaya, Esperanza Garcia, Anne Feltz, Toni Schneider, Jürgen Hescheler, Masanobu Kano, Kenji Sakimura, Masahiko Watanabe, Stéphane Dieudonné, Terrance P. Snutch
J Neurosci. 2009 Aug 5; 29(31): 9668–9682. doi: 10.1523/JNEUROSCI.0362-09.2009
PMCID:
PMC6666586
AbstractArticlePDF–4.3M

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