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Select item 115190171.

SIRT1, a target of miR-708-3p, alleviates fluoride-induced neuronal damage via remodeling mitochondrial network dynamics

Qian Zhao, Guo-yu Zhou, Qiang Niu, Jing-wen Chen, Pei Li, Zhi-yuan Tian, Dong-jie Li, Tao Xia, Shun Zhang, Ai-guo Wang

J Adv Res. 2024 Nov; 65: 197–210. Published online 2023 Nov 28. doi: 10.1016/j.jare.2023.11.032

PMCID:: PMC11519017

Abstract Article PDF–4.6M

Select item 114058702.

Dynamics and necessity of SIRT1 for maternal–zygotic transition

Jan Nevoral, David Drutovic, Michaela Vaskovicova, Michal Benc, Frantisek Liska, Iveta Valentova, Sara Stachovicova, Jan Kubovciak, Jirina Havrankova, Miki Shavit, Ladan Monsef, Maria Iniesta-Cuerda, Tereza Zalmanova, Petr Hosek, Frantisek Strejcek, Milena Kralickova, Jaroslav Petr

Sci Rep. 2024; 14: 21598. Published online 2024 Sep 16. doi: 10.1038/s41598-024-72595-6

PMCID:: PMC11405870

Abstract Article PDF–6.9M

Select item 113584803.

SIRT1 silencing ameliorates malignancy of non-small cell lung cancer via activating FOXO1

Jiawei Chen, Kebin Chen, Shuai Zhang, Xiaopeng Huang

Sci Rep. 2024; 14: 19948. Published online 2024 Aug 28. doi: 10.1038/s41598-024-70970-x

PMCID:: PMC11358480

Abstract Article PDF–7.1M

Select item 113345504.

活性氧簇/沉默信息调节因子1在高氧致支气管上皮细胞损伤中的作用

杨坤, 吴越, 章容, 雷小平, 康兰, 董文斌

Zhongguo Dang Dai Er Ke Za Zhi. 2024 Aug 15; 26(8): 852–860. Chinese. doi: 10.7499/j.issn.1008-8830.2404120

PMCID:: PMC11334550

Abstract Article PDF–3.8M

Select item 112892465.

ZMIZ1 Regulates Proliferation, Autophagy and Apoptosis of Colon Cancer Cells by Mediating Ubiquitin–Proteasome Degradation of SIRT1

Min Huang, Junfeng Wang, Zhengrong Zhang, Xueliang Zuo

Biochem Genet. 2024; 62(4): 3245–3259. Published online 2024 Jan 12. doi: 10.1007/s10528-023-10573-9

PMCID:: PMC11289246

Abstract Article PDF–2.4M

Select item 112501456.

miR‐485‐3p targets SIRT1 in vascular smooth muscle cells mediating the occurrence of aortic dissection

Yuling Xie, Linfeng Xie, Zhihuang Qiu, Jian He, Fei Jiang, Meiling Cai, Yanjuan Lin, Liangwan Chen

J Cell Mol Med. 2024 Jul; 28(13): e18454. Published online 2024 Jul 15. doi: 10.1111/jcmm.18454

PMCID:: PMC11250145

Abstract Article PDF–17M

Select item 111782967.

Clock genes regulate skeletal muscle energy metabolism through NAMPT/NAD⁺/SIRT1 following heavy-load exercise

Yu Xia, Binyu Yao, Zeting Fu, Lunyu Li, Songlin Jin, Bo Qu, Ying Huang, Haili Ding

Am J Physiol Regul Integr Comp Physiol. 2023 Nov 1; 325(5): R490–R503. Published online 2023 Aug 7. doi: 10.1152/ajpregu.00261.2022

PMCID:: PMC11178296

Abstract Article

Select item 111740538.

Sirtuin1 (sirt1) regulates the glycolysis pathway and decreases cisplatin chemotherapeutic sensitivity to esophageal squamous cell carcinoma

Xuewen Yang, Shisen Li, Chunsheng Xu, Shushang Liu, Xiang Zhang, Bo Lian, Mengbin Li

Cancer Biol Ther. 2024; 25(1): 2365449. Published online 2024 Jun 12. doi: 10.1080/15384047.2024.2365449

PMCID:: PMC11174053

Abstract Article PDF–7.5M

Select item 111694839.

The mitochondrial protease ClpP is a druggable target that controls VSMC phenotype by a SIRT1-dependent mechanism

Felipe Paredes, Holly C. Williams, Xuesong Liu, Claire Holden, Bethany Bogan, Yu Wang, Kathryn M. Crotty, Samantha M. Yeligar, Alvaro A. Elorza, Zhiyong Lin, Amir Rezvan, Alejandra San Martin

Redox Biol. 2024 Jul; 73: 103203. Published online 2024 May 21. doi: 10.1016/j.redox.2024.103203

PMCID:: PMC11169483

Abstract Article PDF–7.3M

Select item 1115996510.

Balance between SIRT1 and DBC1 expression is lost in breast cancer

Ji‐Youn Sung, Ranah Kim, Ja‐Eun Kim, Juhie Lee

Cancer Sci. 2010 Jul; 101(7): 1738–1744. Published online 2010 Mar 24. doi: 10.1111/j.1349-7006.2010.01573.x

PMCID:: PMC11159965

Abstract Article PDF–415K

Select item 1115013911.

SIRT1 activation promotes bone repair by enhancing the coupling of type H vessel formation and osteogenesis

Zhikai Liu, Hanghang Liu, Shibo Liu, Bolun Li, Yao Liu, En Luo

Cell Prolif. 2024 Jun; 57(6): e13596. Published online 2024 Jan 11. doi: 10.1111/cpr.13596

PMCID:: PMC11150139

Abstract Article PDF–21M

Select item 1114818412.

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability

YiQing Lü, Tiffany Cho, Saptaparna Mukherjee, Carmen Florencia Suarez, Nicolas S Gonzalez-Foutel, Ahmad Malik, Sebastien Martinez, Dzana Dervovic, Robin Hyunseo Oh, Ellen Langille, Khalid N Al-Zahrani, Lisa Hoeg, Zhen Yuan Lin, Ricky Tsai, Geraldine Mbamalu, Varda Rotter, Patricia Ashton-Prolla, Jason Moffat, Lucia Beatriz Chemes, Anne-Claude Gingras, Moshe Oren, Daniel Durocher, Daniel Schramek

Mol Syst Biol. 2024 Jun; 20(6): 719–740. Published online 2024 Apr 5. doi: 10.1038/s44320-024-00032-x

PMCID:: PMC11148184

Abstract Article PDF–8.1M

Select item 1109664513.

miRNA-142-3p aggravates hydrogen peroxide-induced human umbilical vein endothelial cell premature senescence by targeting SIRT1

Pengfei Tong, Jingke Zhang, Shuang Liu, Jiyang An, Gehan Jing, Laifeng Ma, Ruihua Wang, Zhengfeng Wang

Biosci Rep. 2024 May 29; 44(5): BSR20231511. Published online 2024 May 15. doi: 10.1042/BSR20231511

PMCID:: PMC11096645

Abstract Article PDF–3.9M

Select item 1109359914.

The alanyl-tRNA synthetase AARS1 moonlights as a lactyltransferase to promote YAP signaling in gastric cancer

Junyi Ju, Hui Zhang, Moubin Lin, Zifeng Yan, Liwei An, Zhifa Cao, Dandan Geng, Jingwu Yue, Yang Tang, Luyang Tian, Fan Chen, Yi Han, Wenjia Wang, Shimin Zhao, Shi Jiao, Zhaocai Zhou

J Clin Invest. 2024 May 15; 134(10): e174587. Published online 2024 Mar 21. doi: 10.1172/JCI174587

PMCID:: PMC11093599

Abstract Article PDF–13M

Select item 1105035215.

Neutrophil Elastase Degrades Histone Deacetylases and Sirtuin 1 in Primary Human Monocyte Derived Macrophages

Shuo Zheng, Gamze B. Bulut, Apparao B. Kummarapurugu, Jonathan Ma, Judith A. Voynow

Int J Mol Sci. 2024 Apr; 25(8): 4265. Published online 2024 Apr 12. doi: 10.3390/ijms25084265

PMCID:: PMC11050352

Abstract Article PDF–3.7M

Select item 1101124816.

Analysis of SIRT1 Gene SNPs and Clinical Characteristics in Medication-Related Osteonecrosis of the Jaw

Bence Bojtor, Mihaly Vaszilko, Richard Armos, Balint Tobias, Janos Podani, Szofia Szentpeteri, Bernadett Balla, Balazs Lengyel, Henriett Piko, Anett Illes, Andras Kiss, Zsuzsanna Putz, Istvan Takacs, Janos P. Kosa, Peter Lakatos

Int J Mol Sci. 2024 Apr; 25(7): 3646. Published online 2024 Mar 25. doi: 10.3390/ijms25073646

PMCID:: PMC11011248

Abstract Article PDF–1.5M

Select item 1100841817.

Silent information regulator sirtuin 1 ameliorates acute liver failure via the p53/glutathione peroxidase 4/gasdermin D axis

Xing-Nian Zhou, Quan Zhang, Hong Peng, Yu-Jie Qin, Yu-Hong Liu, Lu Wang, Ming-Liang Cheng, Xin-Hua Luo, Hong Li

World J Gastroenterol. 2024 Mar 21; 30(11): 1588–1608. Published online 2024 Mar 21. doi: 10.3748/wjg.v30.i11.1588

PMCID:: PMC11008418

Abstract Article PDF–18M

Select item 1100677418.

A MiR181/Sirtuin1 regulatory circuit modulates drug response in biliary cancers

Anna Barbato, Fabiola Piscopo, Massimiliano Salati, Carla Pollastro, Lorenzo Evangelista, Luigi Ferrante, Davide Limongello, Simona Brillante, Antonella Iuliano, Luca Reggiani-Bonetti, Maria Salatiello, Antonino Iaccarino, Pasquale Pisapia, Umberto Malapelle, Giancarlo Troncone, Alessia Indrieri, Massimo Dominici, Brunella Franco, Pietro Carotenuto

Clin Exp Med. 2024; 24(1): 74. Published online 2024 Apr 10. doi: 10.1007/s10238-024-01332-0

PMCID:: PMC11006774

Abstract Article PDF–7.2M

Select item 1099190319.

miR-34a induces immunosuppression in colorectal carcinoma through modulating a SIRT1/NF-κB/B7-H3/TNF-α axis

Fanyi Meng, Man Yang, Yinshuang Chen, Weichang Chen, Weipeng Wang

Cancer Immunol Immunother. 2021 Aug; 70(8): 2247–2259. Published online 2021 Jan 25. doi: 10.1007/s00262-021-02862-2

PMCID:: PMC10991903

Abstract Article PDF–4.0M

Select item 1098509520.

SIRT1 ISGylation accelerates tumor progression by unleashing SIRT1 from the inactive state to promote its deacetylase activity

Ji An Kang, Yoon Jung Kim, Kyu Yun Jang, Hye Won Moon, Haeseung Lee, Seonjeong Lee, Hyun Kyu Song, Sang Woo Cho, Yoon Sun Yoo, Hye Gyeong Han, Min-Ju Kim, Myoung Ja Chung, Cheol Yong Choi, Cheolju Lee, Chaeuk Chung, Gang Min Hur, You-Sun Kim, Young Joo Jeon

Exp Mol Med. 2024 Mar; 56(3): 656–673. Published online 2024 Mar 5. doi: 10.1038/s12276-024-01194-2

PMCID:: PMC10985095

Abstract Article PDF–3.2M

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