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Items: 1 to 20 of 147

1.
Functional characterization of the CRY2 circadian clock component variant p.Ser420Phe revealed a new degradation pathway for CRY2
Gizem Cagla Parlak, Ibrahim Baris, Seref Gul, Ibrahim Halil Kavakli
J Biol Chem. 2023 Dec; 299(12): 105451. Published online 2023 Nov 10. doi: 10.1016/j.jbc.2023.105451
PMCID:
PMC10731238
AbstractArticlePDF–2.6M
2.
The central clock controls the daily rhythm of Aqp5 expression in salivary glands
Hitoshi Uchida, Takahiro J. Nakamura, Nana N. Takasu, Aya Obana-Koshino, Hitomi Ono, Takeshi Todo, Takayoshi Sakai, Wataru Nakamura
J Physiol Sci. 2018 Jul; 68(4): 377–385. Published online 2017 May 8. doi: 10.1007/s12576-017-0540-1
PMCID:
PMC10717580
AbstractArticlePDF–2.1M
3.
CircZNF367 promotes osteoclast differentiation and osteoporosis by interacting with FUS to maintain CRY2 mRNA stability
Mingsi Deng, Zhengguang Wang, Jia Luo, Heng Cao, Yong Li, Liangjian Chen, Gengyan Liu
J Orthop Surg Res. 2023; 18: 492. Published online 2023 Jul 11. doi: 10.1186/s13018-023-03955-7
PMCID:
PMC10334599
AbstractArticlePDF–9.2M
4.
Timed exercise stabilizes behavioral rhythms but not molecular programs in the brain’s suprachiasmatic clock
Timna Hitrec, Cheryl Petit, Emily Cryer, Charlotte Muir, Natalie Tal, Jean-Michel Fustin, Alun T.L. Hughes, Hugh D. Piggins
iScience. 2023 Feb 17; 26(2): 106002. Published online 2023 Jan 18. doi: 10.1016/j.isci.2023.106002
PMCID:
PMC9971895
AbstractArticlePDF–5.1M
5.
Distinct phosphorylation states of mammalian CaMKIIβ control the induction and maintenance of sleep
Daisuke Tone, Koji L. Ode, Qianhui Zhang, Hiroshi Fujishima, Rikuhiro G. Yamada, Yoshiki Nagashima, Katsuhiko Matsumoto, Zhiqing Wen, Shota Y. Yoshida, Tomoki T. Mitani, Yuki Arisato, Rei-ichiro Ohno, Maki Ukai-Tadenuma, Junko Yoshida Garçon, Mari Kaneko, Shoi Shi, Hideki Ukai, Kazunari Miyamichi, Takashi Okada, Kenta Sumiyama, Hiroshi Kiyonari, Hiroki R. Ueda
PLoS Biol. 2022 Oct; 20(10): e3001813. Published online 2022 Oct 4. doi: 10.1371/journal.pbio.3001813
PMCID:
PMC9531794
AbstractArticlePDF–3.4M
6.
The secondary pocket of cryptochrome 2 is important for the regulation of its stability and localization
Gizem Cagla Parlak, Bilge Bahar Camur, Seref Gul, Onur Ozcan, Ibrahim Baris, Ibrahim Halil Kavakli
J Biol Chem. 2022 Sep; 298(9): 102334. Published online 2022 Aug 3. doi: 10.1016/j.jbc.2022.102334
PMCID:
PMC9442382
AbstractArticlePDF–2.7M
7.
Heart neurons use clock genes to control myocyte proliferation
Emmanouil Tampakakis, Harshi Gangrade, Stephanie Glavaris, Myo Htet, Sean Murphy, Brian Leei Lin, Ting Liu, Amir Saberi, Matthew Miyamoto, William Kowalski, Yoh-Suke Mukouyama, Gabsang Lee, Liliana Minichiello, Chulan Kwon
Sci Adv. 2021 Dec; 7(49): eabh4181. Published online 2021 Dec 1. doi: 10.1126/sciadv.abh4181
PMCID:
PMC8635446
AbstractArticlePDF–6.2M
8.
Restoring the Molecular Clockwork within the Suprachiasmatic Hypothalamus of an Otherwise Clockless Mouse Enables Circadian Phasing and Stabilization of Sleep-Wake Cycles and Reverses Memory Deficits
Elizabeth S. Maywood, Johanna E. Chesham, Raphaelle Winsky-Sommerer, Michael H. Hastings
J Neurosci. 2021 Oct 13; 41(41): 8562–8576. doi: 10.1523/JNEUROSCI.3141-20.2021
PMCID:
PMC8513698
AbstractArticlePDF–2.0M
9.
CHRONO and DEC1/DEC2 compensate for lack of CRY1/CRY2 in expression of coherent circadian rhythm but not in generation of circadian oscillation in the neonatal mouse SCN
Daisuke Ono, Ken-ichi Honma, Christoph Schmal, Toru Takumi, Takeshi Kawamoto, Katsumi Fujimoto, Yukio Kato, Sato Honma
Sci Rep. 2021; 11: 19240. Published online 2021 Sep 28. doi: 10.1038/s41598-021-98532-5
PMCID:
PMC8479135
AbstractArticlePDF–2.2M
10.
CRY2 missense mutations suppress P53 and enhance cell growth
Alanna B. Chan, Gian Carlo G. Parico, Jennifer L. Fribourgh, Lara H. Ibrahim, Michael J. Bollong, Carrie L. Partch, Katja A. Lamia
Proc Natl Acad Sci U S A. 2021 Jul 6; 118(27): e2101416118. Published online 2021 Jun 28. doi: 10.1073/pnas.2101416118
PMCID:
PMC8271769
AbstractArticlePDF–2.2M
11.
Structural differences in the FAD-binding pockets and lid loops of mammalian CRY1 and CRY2 for isoform-selective regulation
Simon Miller, Ashutosh Srivastava, Yoshiko Nagai, Yoshiki Aikawa, Florence Tama, Tsuyoshi Hirota
Proc Natl Acad Sci U S A. 2021 Jun 29; 118(26): e2026191118. Published online 2021 Jun 25. doi: 10.1073/pnas.2026191118
PMCID:
PMC8255803
AbstractArticlePDF–1.7M
12.
CRYPTOCHROMES confer robustness, not rhythmicity, to circadian timekeeping
Marrit Putker, David C S Wong, Estere Seinkmane, Nina M Rzechorzek, Aiwei Zeng, Nathaniel P Hoyle, Johanna E Chesham, Mathew D Edwards, Kevin A Feeney, Robin Fischer, Nicolai Peschel, Ko‐Fan Chen, Michael Vanden Oever, Rachel S Edgar, Christopher P Selby, Aziz Sancar, John S O’Neill
EMBO J. 2021 Apr 1; 40(7): e106745. Published online 2021 Jan 25. doi: 10.15252/embj.2020106745
PMCID:
PMC8013833
AbstractArticlePDF–1.4M
13.
A circadian clock regulates efflux by the blood-brain barrier in mice and human cells
Shirley L. Zhang, Nicholas F. Lahens, Zhifeng Yue, Denice M. Arnold, Peter P. Pakstis, Jessica E. Schwarz, Amita Sehgal
Nat Commun. 2021; 12: 617. Published online 2021 Jan 27. doi: 10.1038/s41467-020-20795-9
PMCID:
PMC7841146
AbstractArticlePDF–2.2M
14.
Systematic analysis of differential rhythmic liver gene expression mediated by the circadian clock and feeding rhythms
Benjamin D. Weger, Cédric Gobet, Fabrice P. A. David, Florian Atger, Eva Martin, Nicholas E. Phillips, Aline Charpagne, Meltem Weger, Felix Naef, Frédéric Gachon
Proc Natl Acad Sci U S A. 2021 Jan 19; 118(3): e2015803118. Published online 2021 Jan 15. doi: 10.1073/pnas.2015803118
PMCID:
PMC7826335
AbstractArticlePDF–5.8M
15.
Molecular mechanism of the repressive phase of the mammalian circadian clock
Xuemei Cao, Yanyan Yang, Christopher P. Selby, Zhenxing Liu, Aziz Sancar
Proc Natl Acad Sci U S A. 2021 Jan 12; 118(2): e2021174118. Published online 2020 Dec 28. doi: 10.1073/pnas.2021174118
PMCID:
PMC7812753
AbstractArticlePDF–1.6M
16.
Time-restricted feeding prevents obesity and metabolic syndrome in mice lacking a circadian clock
Amandine Chaix, Terry Lin, Hiep D Le, Max W Chang, Satchidananda Panda
Cell Metab. Author manuscript; available in PMC 2020 Dec 21.
Published in final edited form as: Cell Metab. 2019 Feb 5; 29(2): 303–319.e4. Published online 2018 Aug 30. doi: 10.1016/j.cmet.2018.08.004
PMCID:
PMC7751278
AbstractArticlePDF–3.3M
17.
CRY1-CBS binding regulates circadian clock function and metabolism
Sibel Cal-Kayitmazbatir, Eylem Kulkoyluoglu-Cotul, Jacqueline Growe, Christopher P. Selby, Seth D. Rhoades, Dania Malik, Hasimcan Oner, Hande Asimgil, Lauren J. Francey, Aziz Sancar, Warren D. Kruger, John B. Hogenesch, Aalim Weljie, Ron C. Anafi, Ibrahim Halil Kavakli
FEBS J. Author manuscript; available in PMC 2022 Jan 1.
Published in final edited form as: FEBS J. 2021 Jan; 288(2): 614–639. Published online 2020 Jun 9. doi: 10.1111/febs.15360
PMCID:
PMC7648728
AbstractArticlePDF–1.8M
18.
Suppression of Circadian Clock Protein Cryptochrome 2 Promotes Osteoarthritis
Hirofumi Bekki, Tomas Duffy, Naoki Okubo, Merissa Olmer, Oscar Alvarez-Garcia, Katja Lamia, Steve Kay, Martin Lotz
Osteoarthritis Cartilage. Author manuscript; available in PMC 2021 Jul 1.
Published in final edited form as: Osteoarthritis Cartilage. 2020 Jul; 28(7): 966–976. Published online 2020 Apr 24. doi: 10.1016/j.joca.2020.04.004
PMCID:
PMC7476803
AbstractArticlePDF–1.7M
19.
Circadian regulation of c-MYC in mice
Zhenxing Liu, Christopher P. Selby, Yanyan Yang, Laura A. Lindsey-Boltz, Xuemei Cao, Khagani Eynullazada, Aziz Sancar
Proc Natl Acad Sci U S A. 2020 Sep 1; 117(35): 21609–21617. Published online 2020 Aug 19. doi: 10.1073/pnas.2011225117
PMCID:
PMC7474601
AbstractArticlePDF–2.0M
20.
The VIP-VPAC2 neuropeptidergic axis is a cellular pacemaking hub of the suprachiasmatic nucleus circadian circuit
Andrew P. Patton, Mathew D. Edwards, Nicola J. Smyllie, Ryan Hamnett, Johanna E. Chesham, Marco Brancaccio, Elizabeth S. Maywood, Michael H. Hastings
Nat Commun. 2020; 11: 3394. Published online 2020 Jul 7. doi: 10.1038/s41467-020-17110-x
PMCID:
PMC7341843
AbstractArticlePDF–5.3M

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